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A hospital is a place where you generally don't like to go, but are glad that it's there when you need it. It's called ‘clinically clean’. But it is precisely here that we also encounter the term “hospital germ” – an ominous reminder that a place of healing can also pose a health risk. These pathogenic germs are often so resilient that only a few drugs are effective against them. Prof. Susanne Häußler, head of the department “Molecular Bacteriology” at the HZI and TWINCORE in Hannover, studies how these multi-resistant bacteria develop. In the HZI podcast InFact, she explains how faster diagnostics can also improve treatment.

16.01.2025

TWINCORE

HZI Campus

News

A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival. By dissecting the molecular interplay between the virus and its host, the researchers identified novel strategies that HIV-1 employs to ensure its replication while suppressing the host’s cellular defenses. The study was published in the journal Nature Structural and Molecular Biology.

16.01.2025

HIRI

News

Antibiotics are a double-edged sword – they should be as toxic as possible to pathogenic bacteria while being harmless to the cells of the human body. An international research team led by the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has now developed drug candidates that achieve precisely that. The new molecules target a metabolic pathway that only occurs in bacterial cells, thus sparing human cells. The team published its results in the journal Angewandte Chemie International Edition.

13.01.2025

HIPS

Atomic model of Bacteroides thetaiotaomicron RbpB protein with individual B. thetaiotaomicron bacteria in the background

News

Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have identified a protein and a group of small ribonucleic acids (sRNAs) in Bacteroides thetaiotaomicron, which regulate sugar metabolism. These discoveries shed light on how this gut microbe adapts to varying nutritional conditions. The findings deepen our understanding of this bacterium's role in the human gut and may pave the way for new therapeutic strategies to promote health through the microbiota. The study was published in the journal Nature Communications.

09.01.2025

HIRI

News

Researchers at the Helmholtz Centre for Infection Research (HZI) have developed a promising new vaccine technology. Their studies to date show that just one dose of vaccine leads to effective and long-lasting immune protection. The basis of this so-called MCMV vaccine vector technology is the mouse cytomegalovirus (MCMV). It acts as a carrier virus that introduces selected antigens of a pathogen to be vaccinated against into the body. In the follow-up project VIVA-VEK-2, which was launched at the HZI at the beginning of January, a proof-of-concept vaccine candidate against respiratory syncytial virus (RSV) is now to be produced and tested for efficacy and tolerability. The researchers believe that with the new vaccine technology, one vaccine dose could possibly even provide lifelong protection. The project is funded by the GO-Bio initial program of the Federal Ministry of Education and Research (BMBF) over two years with a funding volume of one million euros.

07.01.2025

HZI Campus

HIPS

The Horizon Europe project DEFENDER is exploring new targets for antiviral therapies

News

The interdisciplinary project DEFENDER is developing innovative approaches to combat (re-)emerging viruses. The project, coordinated by the Leibniz Institute of Virology (LIV), is being funded with around eight 9.6 million euros as part of Horizon Europe. Almost 700,000 euros of these will go to Prof. Mark Brönstrup, a researcher at the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF).

06.01.2025

HZI Campus

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HZI in the media

... späten 1990ern hob sie der am Saarbrücker Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS) tätige ...

08.03.2026

Saarbrücker Zeitung

European institutions, including Germany’s Helmholtz Institute for RNA-based Infection Research, Helmholtz Center for Infection Research,

06.03.2026

Clinical Lab Products

Die Zellen kontrollieren die Reaktion des Immunsystems und verhindern Schäden durch Selbstangriffe. Forschende arbeiten daran, sie zur Therapie einzusetzen.

05.03.2026

NDR Norddeutscher Rundfunk

Nachwuchsgruppe „Nanoinfektionsbiologie“ am HZI. Diese Lücke soll das Projekt ONEMUC (Respiratorischer Mukus als One Health-Schnittstelle) ...

03.03.2026

DeutschesGesundheitsPortal

Hochschule Hannover (MHH) und des Helmholz-Zentrums für Infektionsforschung (HZI) erforschen im Rahmen des Projektes StopPSC ( ...

03.03.2026

Biermann Medizin

Mdisk, stock.adobe.com

Braunschweig – Das Helmholtz-Zentrum für Infektionsforschung ( HZI ) in Braunschweig erhält für sein ...

03.03.2026

Deutsches Ärzteblatt

Josef Penninger, wissenschaftlicher Geschäftsführer des Helmholtz Zentrums für Infektionsforschung in Braunschweig und Professor für

01.03.2026

EUROPE SAYS

... Körperzellen. Damit tragen wir, wie das Helmholtz-Zentrum für Infektionsforschung (HZI) es treffend beschreibt, unseren „ganz ...

27.02.2026

MSN Deutschland

Eine Impfung bringt das Immunsystem in Stellung, bevor der echte Erreger kommt. Erfahren Sie, wie ...

26.02.2026

Apotheken Umschau

Livia V. Patrono, one of the senior authors at the Helmholtz Institute for One Health (HIOH) in Germany, said in a statement .

The research

25.02.2026

IFL Science

says Livia Patrono, a veterinarian and disease ecologist at Helmholtz Institute for One Health in Greifswald, Germany. In 2012, an infected

24.02.2026

Science News

... Dr. rer. nat. Jakob Wirbel vom Helmholtz-Zentrum für Infektionsforschung (Braunschweig). Das Experiment aus Stanford sei ...

20.02.2026

Deutsches Ärzteblatt

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