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A team led by Prof. Achim Hoerauf, University Hospital Bonn (UKB), in cooperation with the University of Bonn and the Helmholtz Centre for Infection Research (HZI), is developing the antibiotic corallopyronin A (CorA) as a treatment for the neglected tropical diseases river blindness and lymphatic filariasis. They have now succeeded to enter into a partnership with the Japanese pharmaceutical company Eisai and to raise a large amount of funding. The team's aim is to develop a safe and sustainably effective drug against these worm diseases, which are transmitted to humans by mosquitoes. The people affected mainly live in Africa and tropical regions and urgently need active ingredients that kill the long-lived adult worms. The project is now being funded with around €5.6 million by the Japanese Global Health Innovative Technology (GHIT) Fund.

16.05.2024

HZI Campus

HIPS

Arm with erythema due to Borrelia infection

News

Lyme disease is the most common disease transmitted by tick bites in Germany. Whether a particular genetic predisposition plays a role in the development of the disease and which immunological processes in the body are involved is not yet sufficiently understood. A research team from the Centre for Individualised Infection Medicine (CiiM), a joint institution of the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH), has now discovered a responsible gene variant and the immune parameters involved in cooperation with Radboud University Hospital (Radboundumc; Radboud Universitair Medisch Centrum) and Amsterdam UMC (both in the Netherlands). The researchers have published their findings in two studies. These have been published in the journal Nature Communications and BMC Infectious Diseases.

13.05.2024

HZI Campus

CiiM

News

Dr Katarina Barley, Member of the European Parliament, visited the Helmholtz Centre for Infection Research (HZI) in Braunschweig on Tuesday, 30 April 2024. She was accompanied by Braunschweig's Mayor Dr Thorsten Kornblum and other party colleagues. During the visit, the management of the HZI, led by Prof. Josef Penninger and Christian Scherf, presented the current research program and the future strategy of the center. They also provided insights into the management of research data and the use of artificial intelligence.

30.04.2024

HZI Campus

A participant of the Future Day 2024 in a laboratory

News

Today, around 70 students from years 5 to 9 visited the Helmholtz Centre for Infection Research (HZI) in Braunschweig to get an idea of what it is like to work in a modern research facility. They got a taste of the world of science and its administration in ten scientific and two administrative departments.

25.04.2024

HZI Campus

TWINCORE

News

The antimicrobial potential of CRISPR-Cas systems is promising, yet how to best design or implement CRISPR nucleases remains poorly understood. An international team led by the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has now addressed this knowledge gap. The researchers conducted the first systematic interrogation of CRISPR antimicrobials using multidrug-resistant and hypervirulent bacteria as case studies, revealing wide variations in efficacy that could be predicted via high-throughput screening and machine learning. Their findings were published today in the journal Nucleic Acids Research.

25.04.2024

HIRI

HZI Campus

Vero6 cells (renal epithelial cells) infected with SARS-CoV-2

News

The so-called B cells are part of the immune system's memory. Their memories of previous infections or vaccinations provide the template for antibodies that have a protective effect the next time they come into contact with a pathogen. Researchers at TWINCORE, Centre for Clinical and Experimental Infection Research, have now been able to show that the combination of infection and subsequent vaccination in the case of the SARS-CoV-2 coronavirus even protects against future variants of the virus by the memory cells virtually predicting the future. The team describes how this works in the European Journal of Immunology. The TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Hannover Medical School (MHH).

25.04.2024

TWINCORE

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HZI in the media

Hochschule Hannover, die Universitätsmedizin Göttingen, das Helmholtz-Zentrum für Infektionsforschung in Braunschweig sowie die KI-

07.11.2025

Heise online

... , Leiter der Forschungsgruppe Mikrobielle Wirkstoffe am Helmholtz-Zentrum für Infektionsforschung, zu bedenken. Das erste ...

07.11.2025

Leipziger Volkszeitung (LVZ)

Quelle: Pressemitteilung

HZI-Helmholtz Zentrum für Infektionsforschung ...

04.11.2025

LaborPraxis

Forschende des Helmholtz-Zentrums für Infektionsforschung und der Universität Würzburg entwickeln derzeit einen Kaugummi, der Grippeviren

04.11.2025

Arbeitsmedizin-Sozialmedizin-Umweltmedizin

... Vakzinologie und angewandte Mikrobiologie am Helmholtz-Zentrum für Infektionsforschung. Die M2-Membranproteinhemmer verhindern ...

02.11.2025

Augsburger Allgemeine

... etwas dran ist“, erklärt Biologe Marc Stadler vom Helmholtz-Zentrum für Infektionsforschung gegenüber der Barmer-Krankenkasse. „Es ...

30.10.2025

bild der wissenschaft

could be reintroduced at any time. Epidemiologists at the Helmholtz Center for Infection Research (HZI) have now shown that many people do

23.10.2025

MSN.com

... eingeschleppt werden könnte. Epidemiolog:innen des Helmholtz-Zentrums für Infektionsforschung (HZI) haben nun gezeigt, dass ...

23.10.2025

innovations report

this development, a research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in collaboration with the Swiss

22.10.2025

Phys.org

Malaria-Medikamentes ermöglichen könnte. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung in Zusammenarbeit mit ...

22.10.2025

Verband Deutscher Biologen e.V.

(Bild: DOI: 10.1021/jacs.5c08354 / Hips / CC BY 4.0) Wissenschaftler am Hips entwickelten eine Plattform zur Produktion von Furanoliden, die effektiv gegen Bakterien und Krebszellen wirken können und vielversprechende Wirkstoffe darstellen.

21.10.2025

PROCESS

at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in partnership with the Helmholtz Centre for Infection Research (HZI

20.10.2025

Bioengineer.org

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