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Microscopic image of cells infected with RSV. Green: RSV-F protein labelled with GFP in the cytoplasm of the cells, magenta: RSV-F protein, blue: cell nuclei.

News

The respiratory syncytial virus (RSV) causes severe lower respiratory tract infections, particularly in young children. To date, there is neither an antiviral therapy against the virus nor a vaccination for children. This is why researchers led by Thomas Pietschmann at TWINCORE, a joint institution of Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI) in Braunschweig, are looking for new active substances against RSV. In a large-scale study, they have now identified lonafarnib as a promising candidate. They have published their results in the journal Nature Communications.

12.02.2024

HIPS

TWINCORE

HZI Campus

Sarah Reichardt, Alexander Westermann, Gianluca Prezza and Chase Beisel

News

Researchers from the Würzburg Helmholtz Institute for RNA-based Infection Research (HIRI) deployed CRISPR interference for the first time for the functional characterization of the gut mutualist Bacteroides thetaiotaomicron. They identified a small ribonucleic acid (sRNA) that modulates the microorganisms' growth in the presence of bile. The findings should contribute to a better understanding of the bacterium’s lifestyle in its native environment, the human intestine, and to the development of clinical applications. The study was published in the journal PNAS.

06.02.2024

HIRI

News

As Alliance of Science Organisations in Germany, we emphatically condemn all and any anti-democratic and inhumane endeavours. We vehemently reject the racist statements that have circulated in recent weeks. They are in no way compatible with the values of our organisations. United, we oppose them in the clearest possible terms.

05.02.2024

News

On Friday, February 2, 2024, the German Research Foundation (DFG) and the German Council of Science and Humanities (WR) announced which proposals for new Clusters of Excellence will be invited to submit full proposals. Saarland University (UdS) has successfully cleared this first hurdle with its proposal "nextAID³ - Next Generation of Al-driven Drug Discovery and Development".

02.02.2024

HIPS

News

The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the Broad Institute of MIT and Harvard in the US have now developed a breakthrough tool that overcomes this limitation. Their findings were recently published in the journal Nucleic Acids Research.

01.02.2024

HIRI

Two chimpanzees sitting next to each other

News

An important question in modern life science and medical research is how the microorganisms living in and on a body influence the life processes and thus health and disease of the host organism. Scientists at Kiel University and the Helmholtz Institute for One Health (HIOH), a site of the Helmholtz Centre for Infection Research (HZI), assume that there are connections between the entirety of the body's microbial colonization, the so-called microbiome, and the development of diseases. Chronic inflammatory bowel disease (IBD) in particular is apparently closely linked to the composition and disturbance of the microbiome. At the same time, it is difficult to define a healthy normal state of the human microbial colonization, as it is influenced by many factors and the individual composition varies from person to person.

30.01.2024

HIOH

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HZI in the media

... des Leibniz Lungenzentrums Borstel, des Helmholtz-Instituts für Pharmazeutische Forschung Saarland sowie weiterer wissenschaftlicher ...

12.12.2025

Bionity.COM

angewiesen.“

Josef Penninger, Genetiker und wissenschaftlicher Geschäftsführer des Helmholtz-Zentrums für Infektionsforschung (HZI),

12.12.2025

Brandaktuell

Quelle:

Pressemitteilung Helmholtz-Zentrum für Infektionsforschung HZI ...

10.12.2025

LaborPraxis

Medikament Tolcapon identifiziert. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung (HZI) in Kooperation ...

01.12.2025

Homburg

... wissenschaftlicher Ko-Direktor des Helmholtz Zentrums für Infektionsforschung (HZI). Thomas Pietschmann engagiert sich seit 2023 im ...

28.11.2025

juraforum.de

Dr. Alexander Titz, group leader at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). “Finding new ways to disrupt its

28.11.2025

ARCHYDE

... “, sagte die Leiterin der Epidemiologie am Braunschweiger Helmholtz-Zentrum für Infektionsforschung.

Lange betonte, flächendeckende ...

28.11.2025

Evangelische Zeitung

... ein Zentrum für Quantentechnologie entstehen und das Helmholtz-Institut für Pharmazeutische Forschung ausgebaut werden.

Mehr ...

27.11.2025

Tagesschau

Euro werden investiert in die Erweiterung des Helmholtz-Instituts für Pharmazeutische Forschung Saarland (HIPS). Und ...

27.11.2025

ZEIT online

s drug tolcapone. HIPS is a site of the Helmholtz Center for Infection Research (HZI) in collaboration with Saarland University.

The

26.11.2025

Medical Xpress

... erhielt das Projekt „Citrapeutics“ vom Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig eine Förderung in Höhe ...

25.11.2025

Bionity.COM

led by Hannover Medical School (MHH) and the Helmholtz Center for Infection Research (HZI) has now discovered clear molecular signatures for

24.11.2025

Medical Xpress

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