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The development of effective agents against viral pathogens is of increasing importance for global health. In particular, there is an urgent need for innovative therapeutic options for viral diseases for which no effective vaccine or only inadequate treatment options are available. The Volkswagen Foundation is now funding three projects to research antiviral substances under the leadership of scientists at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Saarland University. The total funding for the three projects amounts to approximately 1.9 million euros.

12.07.2022

HZI Campus

HIPS

News

Although there are many female virologists, microbiologists, and infectious diseases researchers in leadership positions at German universities and research institutes, they are usually not in the public eye. The inaccurate perception of few women being science experts was particularly evident during the first phase of the COVID-19 pandemic, where it was primarily male virologists positioning themselves as advisors to policymakers in the media. HZI virologist Melanie Brinkmann is a founding member of the newly established association Infect-Net.

11.07.2022

HZI Campus

News

The endogenous molecule itaconic acid has antiviral and anti-inflammatory effects, as researchers from TWINCORE have recently shown. In cooperation with scientists from the Helmholtz Centre for Infection Research in Braunschweig and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), they have now investigated the closely related substance citraconic acid. The result: Citraconic acid protects cells through antioxidant and anti-inflammatory properties. It also inhibits the release of flu viruses from human cells. They published these results in the journal Nature Metabolism.

07.07.2022

HZI Campus

TWINCORE

HIPS

News

The LOKI pilot project was launched on 1 July 2022 under the leadership of the Helmholtz Centre for Infection Research (HZI) and in collaboration with the Academy for Public Health Services (AÖGW), the CISPA Helmholtz Center for Information Security, the Forschungszentrum Jülich (FZJ), the German Aerospace Center (DLR) and the Helmholtz Centre for Environmental Research (UFZ). The goal: To provide health authorities with a local early warning system for epidemiologically relevant infection outbreaks in the future - customised and practical.

04.07.2022

HZI Campus

BRICS

News

Hepatitis D is by far the most severe form of chronic viral hepatitis frequently leading to liver failure, hepatocellular carcinoma and death. However, there is very limited knowledge on disease pathophysiology and host-virus interactions explaining the large interindividual variability in the course of hepatitis D. Hannover Medical School (MHH) with its Department of Gastroenterology, Hepatology and Endocrinology and its Centre for Individualised Infection Medicine (CiiM), a joint institution of MHH and the Helmholtz Centre for Infection Research (HZI) in Braunschweig, coordinates an international project for an unbiased screening of a large multicenter cohort of well-defined HDV-infected patients to better understand individual factors determining the outcome of infection and to identify subjects benefitting from currently available treatments. In a highly competitive call for proposals, the D-SOLVE consortium (“Understanding the individual host response against Hepatitis D Virus to develop a personalized approach for the management of hepatitis D”) has received four-year funding of 6.75 million euros from the Horizon 2020 EU Horizon Call „Personalised medicine and infectious diseases: understanding the individual host response to viruses (e.g. SARS-CoV-2)“ of the European Union. In addition to the MHH as project partner and coordinator, institutions from Germany, France, Italy, Sweden and Romania are involved in the project.

22.06.2022

CiiM

News

The coronavirus SARS-CoV-2 can infect various body tissues. While the detection of the virus in the nasopharynx is established as a diagnostic method, the amount of virus found there does not allow a prognosis of the course of the disease. In a recent study, a research team from the Helmholtz Centre for Infection Research (HZI) in cooperation with the University of Rijeka, Croatia, investigated the correlation between the viral load in different tissues and the mortality of patients with a severe course of COVID-19. The researchers show for the first time that viral load can contribute to clinical prognosis, as a higher viral load in the lungs at the time of ventilation correlates with an increased risk of death. In this interview, first author Henrike Maaß and study leader Prof Luka Cicin-Sain, head of the department “Viral Immunology” at HZI, talk about the research results that were published in the journal Viruses MDPI.

20.06.2022

HZI Campus

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HZI in the media

could be reintroduced at any time. Epidemiologists at the Helmholtz Center for Infection Research (HZI) have now shown that many people do

23.10.2025

MSN.com

... eingeschleppt werden könnte. Epidemiolog:innen des Helmholtz-Zentrums für Infektionsforschung (HZI) haben nun gezeigt, dass ...

23.10.2025

innovations report

this development, a research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in collaboration with the Swiss

22.10.2025

Phys.org

Malaria-Medikamentes ermöglichen könnte. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung in Zusammenarbeit mit ...

22.10.2025

Verband Deutscher Biologen e.V.

(Bild: DOI: 10.1021/jacs.5c08354 / Hips / CC BY 4.0) Wissenschaftler am Hips entwickelten eine Plattform zur Produktion von Furanoliden, die effektiv gegen Bakterien und Krebszellen wirken können und vielversprechende Wirkstoffe darstellen.

21.10.2025

PROCESS

at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in partnership with the Helmholtz Centre for Infection Research (HZI

20.10.2025

Bioengineer.org

their biological activity. HIPS is a site of the Helmholtz Center for Infection Research (HZI) in collaboration with Saarland University.

20.10.2025

Phys.org

... die Abteilung „Experimentelle Immunologie“ am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig, lehrt als Professor an ...

17.10.2025

Deutsches Ärzteblatt

Einrichtungen als nationale assoziierte Partner: das Helmholtz-Zentrum für Infektionsforschung Braunschweig, die Universität Bayreuth, das

17.10.2025

AlphaGalileo

... diesem Ergebnis kommt ein Forschungsteam des Helmholtz-Zentrums für Infektionsforschung (HZI) in Zusammenarbeit mit der ...

14.10.2025

Deutsches Ärzteblatt

Individualisierte Infektionsmedizin, einer gemeinsamen Einrichtung des Helmholtz-Zentrums für Infektionsforschung und der MHH. Bis zuletzt

13.10.2025

Springer

Ein Grippe-Test könnte in Zukunft womöglich sehr schnell gehen: einfach ein Kaugummi kauen. Ein deutsches ...

09.10.2025

Apotheken Umschau

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