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Dr. Andreas Pavlou, first author of the study, in the lab

News

Infections in the brain can have serious consequences and are often fatal. The immune defense system works differently here than in the rest of the body. A team of researchers at TWINCORE – Centre for Experimental and Clinical Infection Research in Hanover – has now discovered, in collaboration with partners, which signaling pathways play a central role in communication between immune cells in the brain in their defense against viruses. The results have now been published in the Journal of Neuroinflammation. The TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Hannover Medical School (MHH).

09.07.2025

TWINCORE

[Translate to English:] Empfangsschild des Arabuko-Sokoke-Nationalparks

Story

Natural substances are an important source of active ingredients used in medicine. However, the chemical diversity of fungi in particular has not yet been sufficiently researched. The EU project Mycobiomics, coordinated by Marc Stadler, Head of the Department “Microbial Drugs” at the Helmholtz Centre for Infection Research (HZI), is investigating the biodiversity of fungi in Europe, Asia and Africa in order to identify pharmaceutically valuable secondary metabolites. In May and June 2025, project participants met in Kenya and South Africa for an expedition and a subsequent symposium.

09.07.2025

HZI Campus

The One Health Surveillance team from HIOH receives the award for “Best Research Environment 2024”.

News

Excellent conditions for research, an inspiring atmosphere and fair cooperation: for all this, the research group “One Health Surveillance” (OHS) at the Helmholtz Institute for One Health (HIOH) has been awarded the “Best Research Environment 2024” prize by the Junge Akademie. Under the leadership of Dr. Fee Zimmermann, the OHS group is establishing health and environmental observatories, so-called “One Health Exploratories”, which collect long-term and systematic data on the health of humans, animals and the environment and integrate it into a big picture. The HIOH is a site of the Helmholtz Centre for Infection Research (HZI) in Braunschweig in cooperation with the University of Greifswald, the University Medicine Greifswald and the Friedrich-Loeffler-Institut.

09.07.2025

HIOH

Electron micrograph of coccal bacteria growing in chains

News

Influenza viruses can trigger epigenetic changes in the alveolar epithelium, the cell layer that lines the alveoli, permanent changes in gene activity without changing the DNA itself. These changes have a lasting effect on subsequent immune responses and result in the body no longer being able to react appropriately to the bacterial pathogens in the event of a subsequent infection with pneumococci. A research team at the Helmholtz Centre for Infection Research (HZI) and the University Hospital Magdeburg (UMMD) has published new findings on the long-term consequences of an influenza A infection in a mouse model in the journal Cell Communication and Signaling.

04.07.2025

HZI Campus

Preparing for historical specimen sampling

Story

From 4 to 6 June 2025, the Department “Pathogen Evolution” led by Prof. Dr. Sébastien Calvignac-Spencer at the Helmholtz Institute for One Health (HIOH) conducted a combined retreat and sampling mission at the Institute of Pathology of the University of Veterinary Medicine Vienna — a key collaboration partner for accessing and studying historical pathological specimens in veterinary medicine. HIOH is a site of the Helmholtz Centre for Infection Research (HZI). The visit focused on collecting around 60 historical tissue samples for molecular genetic analyses related to animal disease research, while also offering time for internal discussions on lab optimization, project development, and team building.

03.07.2025

HIOH

News

If an intestinal inhabitant such as the bacterium Escherichia coli (E. coli) becomes resistant to many antibiotics, it can cause serious health problems if it enters the bloodstream. How can such potentially dangerous multi-resistant bacteria be effectively removed from the gut? Researchers from the Helmholtz Centre for Infection Research (HZI), in collaboration with researchers from Hannover Medical School (MHH), explored this question in their latest study.

03.07.2025

HZI Campus

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HZI in the media

... eingeschleppt werden könnte. Epidemiolog:innen des Helmholtz-Zentrums für Infektionsforschung (HZI) haben nun gezeigt, dass ...

23.10.2025

innovations report

this development, a research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in collaboration with the Swiss

22.10.2025

Phys.org

Malaria-Medikamentes ermöglichen könnte. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung in Zusammenarbeit mit ...

22.10.2025

Verband Deutscher Biologen e.V.

(Bild: DOI: 10.1021/jacs.5c08354 / Hips / CC BY 4.0) Wissenschaftler am Hips entwickelten eine Plattform zur Produktion von Furanoliden, die effektiv gegen Bakterien und Krebszellen wirken können und vielversprechende Wirkstoffe darstellen.

21.10.2025

PROCESS

at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in partnership with the Helmholtz Centre for Infection Research (HZI

20.10.2025

Bioengineer.org

their biological activity. HIPS is a site of the Helmholtz Center for Infection Research (HZI) in collaboration with Saarland University.

20.10.2025

Phys.org

... die Abteilung „Experimentelle Immunologie“ am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig, lehrt als Professor an ...

17.10.2025

Deutsches Ärzteblatt

Einrichtungen als nationale assoziierte Partner: das Helmholtz-Zentrum für Infektionsforschung Braunschweig, die Universität Bayreuth, das

17.10.2025

AlphaGalileo

... diesem Ergebnis kommt ein Forschungsteam des Helmholtz-Zentrums für Infektionsforschung (HZI) in Zusammenarbeit mit der ...

14.10.2025

Deutsches Ärzteblatt

Individualisierte Infektionsmedizin, einer gemeinsamen Einrichtung des Helmholtz-Zentrums für Infektionsforschung und der MHH. Bis zuletzt

13.10.2025

Springer

Ein Grippe-Test könnte in Zukunft womöglich sehr schnell gehen: einfach ein Kaugummi kauen. Ein deutsches ...

09.10.2025

Apotheken Umschau

... am 1. Oktober 2025. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung (HZI) in ...

07.10.2025

juraforum.de

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