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The bacterium Pseudomonas aeruginosa is among the most common causes of pneumonia and poses a major challenge to hospitals worldwide. The treatment of infections with Pseudomonas aeruginosa is usually challenging because the bacterium forms so-called biofilms, which protect it from drugs. Dr Martin Empting and his team, in collaboration with several groups at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), have now developed an innovative method to disrupt the formation of these biofilms and thus facilitate the treatment of infections with Pseudomonas aeruginosa. The researchers have published their findings in the journal Advanced Science.

19.03.2021

HZI Campus

HIPS

Grafik Myelom-Zellen mit BCMA-Expression

News

Therapeutically modified white blood cells hold great potential in the treatment of multiple myeloma, a malignant cancer of the bone marrow. However, they can lead to serious resistance in treated patients. In close cooperation, medical doctors and scientists from the University Hospital and the Helmholtz Institute for RNA-based Infection Research in Würzburg have now investigated the causes of this previously unexplained phenomenon. In the process, they uncovered a crucial resistance mechanism. The results were just published in the journal Nature Medicine.

11.03.2021

HIRI

News

An international research team of the Technische Universität Braunschweig and the Helmholtz Centre for Infection Research (HZI), led by the Department of Biotechnology of the TU Braunschweig, has reported on the development of special antibodies against SARS-CoV-2 in the journal Nature Communications. These antibodies prevent the viruses from entering host cells and were isolated from an antibody gene library that had already been produced from immune cells of healthy donors before the pandemic. The study shows how, in the future, active substances to previously unknown, emerging viruses can be produced very quickly without patient material.

11.03.2021

HZI Campus

News

The CoVerage tool analyses the lineage dynamics of SARS-CoV-2 strains, i.e. determines how successfully which virus strain spreads. The web resource uses input from the Gisaid genome database. Gisaid is an international initiative that aims to make research data rapidly available to the public. Scientists from all over the world contribute genome sequences of viruses such as H1N1, influenza or SARS-CoV-2 to the database, thus providing a broad overview of mutations and their genetic differences. However, to predict the spread potential of these mutations, a simple count of incidences is not sufficient.

04.03.2021

HZI Campus

News

The NoCovid group’s scientists, including HZI researchers Prof Melanie Brinkmann and Prof Michael Meyer-Hermann, have called for extensive testing, faster contact tracing, and a rapid rollout of vaccinations in Germany, arguing that only then will it be possible to open up the economy again. Any reopening in the immediate future threatens to quickly undo the hard-won successes of recent weeks, the group writes in a new paper. This means testing must become a part of everyday life. “If we want the economy to recover, any reopening has to be backed by an effective testing strategy and must not be permitted to lead to a resurgence of infections,” says Clemens Fuest, ifo President and a member of the group.

02.03.2021

HZI Campus

Dirk Heinz during his welcoming speech to the Federal Minister of Research, Anja Karliczek

Interview

With the outbreak of the COVID-19 pandemic, the HZI quickly moved into the public spotlight. Scientific Director Prof Dirk Heinz talks about one year of pandemic, the fast establishment of corona research and new challenges

01.03.2021

HZI Campus

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HZI in the media

at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Institute of Molecular Infection Biology (IMIB) in Würzburg has

10.09.2025

Phys.org

Leiter der Abteilung Chemische Biologie am Helmholtz-Zentrum für Infektionsforschung in Braunschweig www.helmholtz-hzi.de ...

10.09.2025

BR Bayerischer Rundfunk

... at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg. The institute is a ...

09.09.2025

Analytik NEWS

Julius-Maximilians-Universität Würzburg (JMU) und assoziiertes Mitglied des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI).

08.09.2025

Verband Deutscher Biologen e.V.

and manufactured the investigational product. The Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) contributed through the

07.09.2025

ScienceDaily

and an associate member of the Helmholtz Institute for RNA-based Infection Research (HIRI).

Additional collaborators included Professors

04.09.2025

Phys.org

JMU) Würzburg und ein Forscher vom Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI) mit ihren Bewerbungen ...

04.09.2025

Open PR.de

Studie und Hersteller des Prüfpräparats. Das Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS) war bei ...

03.09.2025

Biermann Medizin

Das undatierte Foto vom Helmholtz-Zentrum für Infektionsforschung (HZI) zeigt die elektronenmikroskopische Aufnahme von EHEC-Bakterien. © ...

02.09.2025

MSN Deutschland

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