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New, resistance-breaking drugs are urgently needed to effectively treat infections with antibiotic-resistant germs in the future. Researchers from Saarbrücken and Vienna have now found a possible starting point for the development of such drugs in the natural product Saarvienin A. This novel molecule is capable of killing bacteria even if they are already resistant to clinically used antibiotics. The researchers published their findings in the journal Angewandte Chemie International Edition.
28.05.2025
HZI podcast "InFact" with Theresa Graalmann on the topic autoimmune diseases
News
When our immune system chooses the wrong enemy and turns against our own body, autoimmune diseases can result. Dr. Dr. Theresa Graalmann is a physician and clinician scientist who heads the junior research group “Translational Immunology” at TWINCORE – Center for Experimental and Clinical Infection Research. In this episode of the HZI podcast InFact, she explains how rheumatism, lupus, and vascular inflammation develop and how doctors and scientists work together to incorporate patient data and state-of-the-art cell analyses directly into the development of new therapeutic approaches.
27.05.2025
Study authors Maureen Obara and Dr Matthias Bruhn
News
Monoclonal antibodies against SARS-CoV-2 were considered a promising approach for the prevention and therapy of corona virus infections. However, the ongoing evolution of the virus regularly produces new variants that are no longer neutralized by the antibodies. Researchers from TWINCORE, together with partners from Hanover and Bern, have now been able to clarify the underlying mechanism in more detail. The TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Hannover Medical School (MHH). Instead of using a single antibody, they propose the combination of several antibodies for treatment. They have published their findings in the scientific journal eBioMedicine.
26.05.2025
Group photo
News
Decisions have been made on future Clusters of Excellence in the second round of competition under the Excellence Strategy – the joint initiative of the federal and state governments to further strengthen top-level research at universities in Germany. The Helmholtz Centre for Infection Research (HZI) is part of two of the funded Clusters of Excellence together with university partners: RESIST and NUCLEATE. RESIST at Hannover Medical School (MHH) will receive funding for another seven years. In this cluster, scientists are investigating how people who are susceptible to infection can be better protected. In the newly approved NUCLEATE cluster at the Julius-Maximilians-Universität Würzburg (JMU) with the Technical University of Munich and the Ludwig-Maximilians-Universität München, group leaders from the Helmholtz Institute for RNA-based Infection Research (HIRI), a site of the HZI in cooperation with the JMU, are conducting research into nucleic acid-based therapies. A total of 70 Clusters of Excellence were selected for funding.
26.05.2025
Close-up of bat
News
Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses cause in humans, bats generally do not show obvious signs of viral illness following infection. An international research team led by Dr. Max Kellner and Prof. Josef Penninger, Scientific Director of the Helmholtz Centre for Infection Research (HZI), has developed an innovative organoid research platform that allowed them to closely investigate the cellular antiviral defense mechanisms of mucosal epithelial tissues of bats. The results have now been published in Nature Immunology and could pave the way for the development of new therapies against viral diseases.
21.05.2025
Group photo ENDURIVAC
News
Yesterday, the biomedical project forge of the state of Lower Saxony reviewed the most promising ideas from across the region and selected the winners: At the fourth portfolio conference of the Institute for Biomedical Translation (IBT) Lower Saxony, a high-caliber jury selected projects from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, the University Medical Center Göttingen (UMG) and TWINCORE - Centre for Experimental and Clinical Infection Research, which will receive funding of almost 3 million euros. TWINCORE is a joint institution of the HZI and Hannover Medical School (MHH). A total of 25 million euros will be available to the IBT Lower Saxony until 2028 to accelerate the transfer of cutting-edge research in the life sciences in Lower Saxony and bring it to the world in the form of start-ups and entrepreneurial ideas.
14.05.2025

HZI in the media

before and we just didn’t notice?” asks Fabian Leendertz, director of the Helmholtz Institute for One Health. He points out that wildlife

25.06.2025
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Resurgence

... Samonellen liegen unter Schwarzlicht im Labor des Helmholtz-Zentrums in Braunschweig. Foto: Peter Steffen/dpa ...

23.06.2025
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Kurier

Slevogt from the MHH and the Helmholtz Centre for Infection Research (“Helmholtz-Zentrum für Infektionsforschung“; HZI). An application for

23.06.2025
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Trading View

... der Universität des Saarlandes , des Helmholtz-Instituts für Pharmazeutische Forschung Saarland (HIPS) und internationalen Teams ...

19.06.2025
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CHIP

Forschende am Helmholtz-Zentrum für Infektionsforschung in Braunschweig (Niedersachsen) arbeiten an einer neuer Impfstoff-Technologie, die

18.06.2025
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17:30 SAT.1 REGIONAL

... machen

 

Die Studie der Wissenschaftler des Helmholtz-Zentrums für Infektionsforschung (HZI) in Braunschweig will daher vor ...

18.06.2025
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Cityblick 24

including Dr. Max Kellner and Prof.‌ Josef Penninger of the⁢ Helmholtz Center for Infection Research (HZI), explored this ‌resilience.They

17.06.2025
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Newsdirectory3

the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Chair of Microbiology of the Julius-Maximilians-Universität Würzburg

17.06.2025
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Phys.org

Instituts für RNA-basierte Infektionsforschung (HIRI), einem Standort des Braunschweiger Helmholtz-Zentrums für Infektionsforschung (HZI) ...

17.06.2025
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