Newsroom

Cryo-electron microscopy image: The anti-CRISPR protein AcrVIB1 (magenta) attaches to the nuclease Cas13b (light gray)

News

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, scientists are searching for mechanisms that can regulate or inhibit the systems’ activity. Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, in collaboration with the Helmholtz Centre for Infection Research (HZI) in Braunschweig, has uncovered the precise way AcrVIB1 works that expands the known means by which Acrs can shut down CRISPR. The results were published today in the journal Molecular Cell.

17.02.2025

HZI Campus

HIRI

News

Construction of a modern new building for the Helmholtz Institute for One Health (HIOH) will begin this year on the University of Greifswald's Berthold-Beitz-Platz campus. Founded in 2021 as a site of the Helmholtz Centre for Infection Research (HZI), the institute works closely with its local founding partners, the University of Greifswald, the University Medical Centre Greifswald and the Friedrich-Loeffler-Institut. In line with the One Health approach, which considers human, animal and environmental health as an inseparable whole, the HIOH combines a variety of scientific disciplines. The common goal is to better understand the emergence of zoonotic diseases, antimicrobial resistance and the evolution of pathogens, and thus reduce the risk of new pandemics. In an increasingly interconnected world, in which pathogens that can be transmitted from animals to humans can travel across the globe in no time and develop resistance to drugs, the HIOH is making a decisive contribution to research into the origin and transmission of such infections – and is thus creating the basis for effective pandemic prevention measures.

06.02.2025

HIOH

News

The only natural host of the hepatitis C virus (HCV) is humans. Model organisms for laboratory studies, especially mice, cannot be infected which makes the search for a vaccine against HCV extremely difficult because the protective effect cannot be tested directly. In order to understand why the virus cannot infect mice and to enable the development of new animal models, researchers at TWINCORE in Hannover have generated an adapted virus variant that can infect mouse liver cells in vitro. They have now published their work in the Journal of Hepatology Reports. The TWINCORE is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Hannover Medical School (MHH).

31.01.2025

HZI Campus

TWINCORE

Illustration of coronaviruses such as SARS-CoV-2

News

Viruses are masters at disguise. When they are pushed too far by our immune system, they send new virus variants into play that are no longer recognized by immune cells. They escape our immune system by mutating the virus structures that are recognized by antibodies. In order to adapt vaccines to new circulating virus variants as promptly as possible, it is first necessary to find out which among the numerous mutations are actually responsible for the immune escape of a new virus variant. Researchers at the Helmholtz Centre for Infection Research (HZI), in collaboration with the Hannover Medical School (MHH), have developed a method called reverse mutational scanning that can be used to detect such mutations quickly and reliably. The study has been published in the journal Nature Communications.

30.01.2025

HZI Campus

CiiM

News

The European Research Council (ERC) has announced the results of the latest round of its “Proof of Concept Grant” 2024 competition. Among the researchers selected for funding is Prof. Yang Li, co-director of the Centre for Individualised Infection Medicine (CiiM) and head of the research department “Bioinformatics for Individualised Medicine”, who has thus been awarded one of the coveted ERC grants for the second time. In total, the ERC selected 134 projects for funding of 150,000 euros each. The CiiM is a branch of the Helmholtz Centre for Infection Research (HZI), which is operated jointly with the Hannover Medical School (MHH).

29.01.2025

CiiM

News

The long-standing President of the Thünen Institute, Prof. Dr Folkhard Isermeyer, passed away on 14 January 2025 at the age of 67. With his passing, the Thünen Institute has not only lost its ‘architect’, an excellent scientist and clever strategist, but also a personality who led with trust, an open ear and human warmth.

23.01.2025

Back to the first page
...
23
24
25
26
...
148

HZI in the media

international institutions including Trinity College Dublin, the Helmholtz Institute for One Health, Université Paris 1 Panthéon-Sorbonne,

02.09.2026

EurekAlert!

... die präzise Zerspanung großer Bauteile. Das Helmholtz-Zentrum für Infektionsforschung in Braunschweig und die Medizinische Hochschule ...

01.09.2026

Regionalupdate.de

... zunehmen. Mit der Gründung des HIOH im Jahr 2021 als Standort des Braunschweiger Helmholtz-Zentrums für ...

31.08.2026

Management & Krankenhaus

Wie man sich mit Mpox anstecken kann und warum sich Personen mit häufig wechselnden Sexpartnern impfen lassen sollten.

28.08.2026

Apotheken Umschau

... des neuen Forschungsgebäudes des Helmholtz-Instituts für One Health (HIOH) in Greifswald (Landkreis Vorpommern-Greifswald) gelegt

. ...

28.08.2026

Tagesschau

How Bacteria Develop Resistance to Antisense Antibiotics—and How Future Therapies Can Be Made Less Susceptible to It

28.08.2026

Bionity.COM

Infection Research; the RESIST Cluster of Excellence; and the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has

27.08.2026

Phys.org

... Arbeiten am Universitätsklinikum Köln und am Helmholtz-Zentrum für Infektionsforschung startet nun die Entwicklung und GMP- ...

26.08.2026

healthcare-in-europe.com

Infos: Herpesviren – Eine große Familie Helmholtz Zentrum für Infektionsforschung www.helmholtz-hzi.de/wissen/wissensportal/ ...

25.08.2026

SWR4 Rheinland-Pfalz

An einer weiteren Station veranschaulicht das Helmholtz-Institut für Pharmazeutische Forschung, wie die Entwicklung neuer ...

25.08.2026

MSN Deutschland

Technologien“ im HUMAN-Projekt am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig . Im Mittelpunkt ihrer Arbeit steht ...

23.08.2026

Regional Heute

... Medizinischen Hochschule Hannover (MHH) und des Helmholtz-Zentrums für Infektionsforschung (HZI). Dafür setzten die Forschenden sechs ...

19.08.2026

Pharmazeutische Zeitung

Register now for the HZI newsletter

and stay up to date!

Email address *

We use rapidmail to send our newsletter. I agree that my data entered here will be transmitted to rapidmail. I have taken note of the HZI's privacy policy and have been informed of my rights.