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Illustration of a large monocyte surrounded by smaller red blood cells

News

Not only does our body change with age, but so does our immune system. A recent study led by the Centre for Individualised Infection Medicine (CiiM) shows exactly how immune cells age and how infections and vaccinations can influence this process. The CiiM is a joint initiative of the Helmholtz Centre for Infection Research (HZI) and Hannover Medical School (MHH). Using a big data approach, the researchers have developed a computer model called the “Single-Cell Immune Aging Clock”, which can be used to determine aging processes within individual immune cells. The scientists are making the innovative aging clock freely available for further research. They hope that it will serve as a useful tool to better understand the aging processes of the immune system, particularly with the context of infectious diseases and immune disorders. The study has been published in the journal Nature Aging.

19.03.2025

CiiM

News

Regarding the current reporting on the origin of the coronavirus SARS-CoV-2, Prof. Fabian Leendertz, Director of the Helmholtz Institute for One Health (HIOH), makes the following statement: “Based on the data published to date, it can be assumed that the transmission to humans took place via intermediate hosts (e.g. animal farms), as the contacts and risks are much higher there. This data has been published in various WHO reports and relevant peer-reviewed scientific publications. If there is now other and new data that supports an origin in the laboratory, then that is a different picture. We now have to wait until this data has been examined and reviewed by experts.”

13.03.2025

HIOH

News

In May 2022, alarming headlines emerged: A mysterious and deadly disease was spreading in Central Africa. Was this the beginning of a new pandemic? Today, we know that it was Mpox (formerly known as monkeypox), a viral disease that has once again been declared a public health emergency. In this episode of the HZI podcast Infact, Dr Julia Port, head of the research group “Laboratory of Transmission Immunology” at the Helmholtz Centre for Infection Research (HZI), discusses virus transmission and the role of the immune system. Her research bridges immunology, viral ecology, and global health.

27.02.2025

HZI Campus

Fabian Leendertz with a group of students standing with their backs to the camera

News

Today, the Citizen Science project CiFly will enter its second year. This year, 9th and 10th grade students from the Alexander-von-Humboldt-Gymnasium will again have the opportunity to get to know the Helmholtz Institute for One Health (HIOH), but also the chance to explore the biobank of the University Medical Center and the Greifswald Zoo from the perspective of a researcher.

27.02.2025

HIOH

[Translate to English:] 3D-kontrastierte Oberflächenstruktur von LasB (beige) mit einem Inhibitor der 3. Generation (dunkelblau), der Zink (grau) bindet.

News

Infectious keratitis blinds 1.5 million people worldwide every year. This severe eye disease is often caused by the hospital germ Pseudomonas aeruginosa, which the World Health Organization considers one of the most dangerous bacteria of its kind. Now, scientists at Saarland University and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have found a way to combat this resilient pathogen. Their study has been published in Advanced Science. The HIPS is a site of the Helmholtz Centre for Infection Research (HZI) in collaboration with Saarland University.

24.02.2025

HIPS

HZI Campus

Cryo-electron microscopy image: The anti-CRISPR protein AcrVIB1 (magenta) attaches to the nuclease Cas13b (light gray)

News

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, scientists are searching for mechanisms that can regulate or inhibit the systems’ activity. Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, in collaboration with the Helmholtz Centre for Infection Research (HZI) in Braunschweig, has uncovered the precise way AcrVIB1 works that expands the known means by which Acrs can shut down CRISPR. The results were published today in the journal Molecular Cell.

17.02.2025

HZI Campus

HIRI

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HZI in the media

... Pneumologie an der UMMD sowie dem Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig.

In Folge der ...

30.06.2025

Presseportal Magdeburg

Ernährungsweise zusammen.

Lisa Osbelt-Block

Am Helmholtz-Zentrum für Infektionsforschung in Braunschweig geht sie der Beziehung zwischen

28.06.2025

Der Spiegel

before and we just didn’t notice?” asks Fabian Leendertz, director of the Helmholtz Institute for One Health. He points out that wildlife

25.06.2025

Resurgence

... Samonellen liegen unter Schwarzlicht im Labor des Helmholtz-Zentrums in Braunschweig. Foto: Peter Steffen/dpa ...

23.06.2025

Kurier

Slevogt from the MHH and the Helmholtz Centre for Infection Research (“Helmholtz-Zentrum für Infektionsforschung“; HZI). An application for

23.06.2025

Trading View

... der Universität des Saarlandes , des Helmholtz-Instituts für Pharmazeutische Forschung Saarland (HIPS) und internationalen Teams ...

19.06.2025

CHIP

Forschende am Helmholtz-Zentrum für Infektionsforschung in Braunschweig (Niedersachsen) arbeiten an einer neuer Impfstoff-Technologie, die

18.06.2025

17:30 SAT.1 REGIONAL

... machen

Die Studie der Wissenschaftler des Helmholtz-Zentrums für Infektionsforschung (HZI) in Braunschweig will daher vor ...

18.06.2025

Cityblick 24

including Dr. Max Kellner and Prof.‌ Josef Penninger of the⁢ Helmholtz Center for Infection Research (HZI), explored this ‌resilience.They

17.06.2025

Newsdirectory3

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