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In May 2022, alarming headlines emerged: A mysterious and deadly disease was spreading in Central Africa. Was this the beginning of a new pandemic? Today, we know that it was Mpox (formerly known as monkeypox), a viral disease that has once again been declared a public health emergency. In this episode of the HZI podcast Infact, Dr Julia Port, head of the research group “Laboratory of Transmission Immunology” at the Helmholtz Centre for Infection Research (HZI), discusses virus transmission and the role of the immune system. Her research bridges immunology, viral ecology, and global health.

27.02.2025

HZI Campus

Fabian Leendertz with a group of students standing with their backs to the camera

News

Today, the Citizen Science project CiFly will enter its second year. This year, 9th and 10th grade students from the Alexander-von-Humboldt-Gymnasium will again have the opportunity to get to know the Helmholtz Institute for One Health (HIOH), but also the chance to explore the biobank of the University Medical Center and the Greifswald Zoo from the perspective of a researcher.

27.02.2025

HIOH

[Translate to English:] 3D-kontrastierte Oberflächenstruktur von LasB (beige) mit einem Inhibitor der 3. Generation (dunkelblau), der Zink (grau) bindet.

News

Infectious keratitis blinds 1.5 million people worldwide every year. This severe eye disease is often caused by the hospital germ Pseudomonas aeruginosa, which the World Health Organization considers one of the most dangerous bacteria of its kind. Now, scientists at Saarland University and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have found a way to combat this resilient pathogen. Their study has been published in Advanced Science. The HIPS is a site of the Helmholtz Centre for Infection Research (HZI) in collaboration with Saarland University.

24.02.2025

HIPS

HZI Campus

Cryo-electron microscopy image: The anti-CRISPR protein AcrVIB1 (magenta) attaches to the nuclease Cas13b (light gray)

News

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, scientists are searching for mechanisms that can regulate or inhibit the systems’ activity. Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, in collaboration with the Helmholtz Centre for Infection Research (HZI) in Braunschweig, has uncovered the precise way AcrVIB1 works that expands the known means by which Acrs can shut down CRISPR. The results were published today in the journal Molecular Cell.

17.02.2025

HZI Campus

HIRI

News

Construction of a modern new building for the Helmholtz Institute for One Health (HIOH) will begin this year on the University of Greifswald's Berthold-Beitz-Platz campus. Founded in 2021 as a site of the Helmholtz Centre for Infection Research (HZI), the institute works closely with its local founding partners, the University of Greifswald, the University Medical Centre Greifswald and the Friedrich-Loeffler-Institut. In line with the One Health approach, which considers human, animal and environmental health as an inseparable whole, the HIOH combines a variety of scientific disciplines. The common goal is to better understand the emergence of zoonotic diseases, antimicrobial resistance and the evolution of pathogens, and thus reduce the risk of new pandemics. In an increasingly interconnected world, in which pathogens that can be transmitted from animals to humans can travel across the globe in no time and develop resistance to drugs, the HIOH is making a decisive contribution to research into the origin and transmission of such infections – and is thus creating the basis for effective pandemic prevention measures.

06.02.2025

HIOH

Story

The Republic of Côte d'Ivoire is a vibrant country in West Africa with rich cultural traditions and diverse ecosystems. Despite its beauty and vitality, the country faces significant challenges in its health system, particularly with regard to infectious diseases and antimicrobial resistance (AMR). These challenges are exacerbated by limited healthcare expenditure, which remains among the lowest in the world. Infectious diseases, the risk of zoonotic transmission (i.e., infectious diseases that can spread from animals to humans) and the high burden of healthcare-associated infections pose serious public health problems and make Côte d'Ivoire a priority country for international health cooperation.

03.02.2025

HIOH

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HZI in the media

Medikament Tolcapon identifiziert. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung (HZI) in Kooperation ...

01.12.2025

Homburg

... wissenschaftlicher Ko-Direktor des Helmholtz Zentrums für Infektionsforschung (HZI). Thomas Pietschmann engagiert sich seit 2023 im ...

28.11.2025

juraforum.de

Dr. Alexander Titz, group leader at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). “Finding new ways to disrupt its

28.11.2025

ARCHYDE

... “, sagte die Leiterin der Epidemiologie am Braunschweiger Helmholtz-Zentrum für Infektionsforschung.

Lange betonte, flächendeckende ...

28.11.2025

Evangelische Zeitung

... ein Zentrum für Quantentechnologie entstehen und das Helmholtz-Institut für Pharmazeutische Forschung ausgebaut werden.

Mehr ...

27.11.2025

Tagesschau

Euro werden investiert in die Erweiterung des Helmholtz-Instituts für Pharmazeutische Forschung Saarland (HIPS). Und ...

27.11.2025

ZEIT online

s drug tolcapone. HIPS is a site of the Helmholtz Center for Infection Research (HZI) in collaboration with Saarland University.

The

26.11.2025

Medical Xpress

... erhielt das Projekt „Citrapeutics“ vom Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig eine Förderung in Höhe ...

25.11.2025

Bionity.COM

led by Hannover Medical School (MHH) and the Helmholtz Center for Infection Research (HZI) has now discovered clear molecular signatures for

24.11.2025

Medical Xpress

Medizinischen Hochschule Hannover (MHH) und dem Helmholtz-Zentrum für Infektionsforschung (HZI), hat nun eindeutige molekulare Signaturen ...

24.11.2025

DeutschesGesundheitsPortal

Braunschweig. Das Helmholtz-Zentrum für Infektionsforschung (HZI) bringt anlässlich seines 60. Jubiläums seine Forschung vom 3. ...

22.11.2025

Regional Heute

Universität Hannover (LUH), dem Helmholtz Zentrum für Infektionsforschung (HZI) in Braunschweig, der Technischen Universität Braunschweig ...

21.11.2025

Medizinische Hochschule Hannover

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