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Antibacterial drugs are important to treat infections. But increasing bacterial resistance to current drugs — making them ineffective or only partially effective — means that new ones are urgently needed. Building on previous work, researchers from the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), together with an international team of collaborators, have demonstrated a potential antibacterial treatment from a biosynthetic derivative of darobactin, a bacterial natural product. The team reports proof-of-concept animal trials on infections caused by bacteria, including Escherichia coli and Acinetobacter baumannii that are known to develop drug-resistance. This ACS Infectious Diseases study was published during the World Health Organization’s World Antimicrobial Resistance (AMR) Awareness Week from 18 to 24 November 2024. The HIPS is a site of the Helmholtz Centre for Infection Research (HZI) in cooperation with Saarland University.

20.11.2024

HZI Campus

HIPS

Interview, Story

The annual World Antimicrobial Resistance Awareness Week (WAAW) is a global campaign to draw attention to the dangers of antimicrobial resistance (AMR). It also aims to inform people about behaviors that can reduce the occurrence and spread of drug-resistant infections. The WAAW is celebrated every year from November 18 to 24. The motto in 2024 is “Educate. Advocate. Act now.”.

18.11.2024

HIPS

HIOH

HZI Campus

News

Professors Ivo Boneca (Institut Pasteur, Paris), Mark Brönstrup (Helmholtz Centre for Infection Research, Braunschweig), and Christophe Zimmer (University of Würzburg) have jointly been awarded one of the most prestigious European research prizes, an ERC Synergy Grant worth eleven million euros. The trio is pursuing an AI-based approach to make the systematic search for new antibiotics more efficient.

05.11.2024

HZI Campus

[Translate to English:] Dr Martin Keller.

News

The Helmholtz Association has appointed internationally respected US-based scientist Martin Keller as its new president. Following a unanimous vote by the Assembly of Members last Wednesday, the Helmholtz Senate approved the decision today. Keller has lived in the United States for nearly three decades, during which he has held various scientific leadership roles at prominent institutions. Since 2015, he has directed the National Renewable Energy Laboratory (NREL) in Golden, Colorado. His term begins on November 1, 2025.

30.10.2024

News

The Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) is growing: In the past three years, the institute – a site of the Helmholtz Centre for Infection Research (HZI) in collaboration with Saarland University (UdS) – has appointed five professors together with the UdS. To further strengthen the focus on active ingredients at the Saarbrücken campus, the university has filled two additional professorships in this field. To ensure that the researchers have adequate laboratory and office space, several construction projects are planned that will provide space for 330 researchers by 2029. The structural expansion is financed by federal and state development funds totaling 55.7 million euros.

29.10.2024

HIPS

News

Our immune system successfully defends itself against pathogens on a daily basis - often without us realizing it. We notice other encounters with pathogens through cold symptoms, fever or a red, swollen area. Our immune system is then working at full speed. Prof. Kathrin de la Rosa wants to be one step ahead of the pathogens. Since 2024, she has headed the department “Personalized Immunotherapy” at the Centre for Individualized Infection Medicine (CiiM) - a joint institution of Hannover Medical School and the HZI. In the HZI podcast InFact, she reports on how she wants to improve individual defense mechanisms in people whose immune system cannot cope with the pathogen on its own and explains why she is copying tricks from nature.

28.10.2024

CiiM

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HZI in the media

... die klinische Validität. Ein Forschungsteam des Helmholtz-Zentrums für Infektionsforschung (HZI) hat mit „Metax“ nun einen ...

02.10.2026

Analytik.de

Mikrobiologen auch Kolleg*innen vom IST Austria und dem HZI in Braunschweig gehören: Inhibitoren von Aktin unterbinden diese dynamischen

01.10.2026

Science.apa.at

... der Medizinischen Hochschule Hannover sowie am Helmholtz-Zentrum für Infektionsforschung tätig ist. Als Co-Autor ist zudem ...

30.09.2026

Ad Hoc News

also included Japanese microbiologists and collaborators from IST Austria and HZI Braunschweig (Germany), demonstrated that actin inhibitors

30.09.2026

Phys.org

for cell movement. Scientists from the Helmholtz Center for Infection Research (HZI) in Braunschweig have provided evidence that Profilin

29.09.2026

TakeToNews

Biology (BRICS), a joint research center of the Helmholtz Centre for Infection Research (HZI) and Technische Universität Braunschweig.

29.09.2026

Phys.org

... treffsicher .

Das Helmholtz-Zentrum für Infektionsforschung:

Wissenschaftler:innen am Helmholtz-Zentrum für Infektionsforschung (HZI) ...

28.09.2026

DeutschesGesundheitsPortal

... Fluorchinolon-Resistenz aktiv

Forscher des Helmholtz-Zentrums für Infektionsforschung (HZI) um Dr. Jennifer Herrmann haben ...

27.09.2026

scinexx - Das Wissensmagazin

Die WHO nennt Antibiotikaresistenzen (AMR) eine der größten globalen Gesundheitsbedrohungen. Bereits heute töten resistente Keime jährlich mehr als eine Million Menschen direkt und tragen zu fast fünf Millionen Todesfällen bei. Tendenz: steigend. Für ein wirkungsvolles Dagegenha

25.09.2026

Sysmex

... die Resistenzen": HZI-Podcast InFact mit Mark Brönstrup

Quelle: Helmholtz-Zentrum für Infektionsforschung (HZI)

Biodiversität ...

25.09.2026

Analytik NEWS

Quelle: Pressemitteilung

Helmholtz-Zentrum für Infektionsforschung

24.09.2026

LaborPraxis

Lange galt Dopamin als simples Glückshormon. Alena Buyx zeigt in ihrer Sendung, dass der Botenstoff ...

24.09.2026

3sat

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