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Decorative image to represent the new databases

News

Modern pharmaceutical research generates large amounts of data faster than ever before. To analyze and evaluate this data, it is collected and structured in extensive databases and thus provides the basis for the development of new active ingredients. Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have now published two such databases. While the "ABC-HuMi" database focuses on genetic data from microorganisms that colonize humans, "ZEBRA" provides a high-resolution cell atlas of the human and mouse brain. Both databases were published in the annual database issue of the journal Nucleic Acids Research.

09.01.2024

HIPS

News

Despite the end of the pandemic, COVID-19 continues to pose a serious health threat. Most individuals have established robust immune protection and do not develop severe disease but the infection can still lead to marked and sometimes long-lasting disease symptoms. In the late summer of 2023 a new SARS-CoV-2 variant emerged, BA.2.86 (Pirola), which, based on genetics, differs markedly from all previously circulating variants.

09.01.2024

HZI Campus

Group Picture of Participants of the ENLIGHT-TEN+ Winter School

News

From 13 to 17 November 2023, 28 young scientists gathered at BAYER in Berlin to take part in the Winter School for Translational Medical Research and Drug Development organized by ENLIGHT-TEN+ and EATRIS. Experts from science and industry provided in-depth insights into the basics of drug production and introduced the young scientists to the processes through interactive exercises and case studies. BAYER is a member of the ENLIGHT-TEN+ consortium and was primarily responsible for organizing the Winter School.

21.12.2023

HZI Campus

Story

Vaccinations do not always live up to what we would want them to do – so far, anyway. But they are still invaluable for our health and life in our communities.

12.12.2023

HZI Campus

[Translate to English:] Endogener ASC-Speck, abgebildet in 3D mit dSTORM. © iScience, CC-BY-4.0

News

A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer’s, Parkinson’s, multiple sclerosis, atherosclerosis, gout, and type II diabetes. The NLRP3 inflammasome occurs primarily in specialized immune cells in the blood and elsewhere. It is a dense complex in which several proteins interact with each other. A key protein in this complex is known by the abbreviation ASC. In non-activated immune cells, it is distributed homogeneously throughout the cell. If the NLRP3 inflammasome is activated, all of the ASC protein present in the cell aggregates in the inflammasome complex. Under an ordinary fluorescence microscope, the ASC protein, once labeled, appears as a single, bright, nearly round spot. Due to the small size and high density of this ASC speck, scientists have been unable to elucidate details of its structure inside cells. Different models were proposed in the scientific literature but a comprehensive understanding was missing.

11.12.2023

HZI Campus

Symbol image; hand turns an equal and an unequal sign between the symbols for male and female gender

Story

Am I more likely to have a mild case of pneumonia or is it more likely to be life-threatening? What is my risk of side effects from COVID-19 vaccination? Do I belong to a group of people who are more likely to contract chronic viral hepatitis than others? The answers to these questions vary – depending on your sex and gender. Hospitalised for pneumonia, males are twice as likely as females to need to be transferred to intensive care (see list of sources). Females, in turn, are more than twice as likely as males to suffer side effects from the COVID-19 vaccine. And chronic hepatitis B is more common among males than among females.

08.12.2023

CiiM

HZI Campus

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HZI in the media

Technische Universität Braunschweig, das HZI – Helmholtz-Zentrum für Infektionsforschung in Braunschweig sowie die Medizinische Hochschule ...

04.10.2026

schleswig-holstein.de

the Institute of Science and Technology Austria and the Helmholtz Centre for Infection Research in Braunschweig, Germany. Their combined

04.10.2026

Scienmag Science Magazine

... die klinische Validität. Ein Forschungsteam des Helmholtz-Zentrums für Infektionsforschung (HZI) hat mit „Metax“ nun einen ...

02.10.2026

Analytik.de

Mikrobiologen auch Kolleg*innen vom IST Austria und dem HZI in Braunschweig gehören: Inhibitoren von Aktin unterbinden diese dynamischen

01.10.2026

Science.apa.at

... der Medizinischen Hochschule Hannover sowie am Helmholtz-Zentrum für Infektionsforschung tätig ist. Als Co-Autor ist zudem ...

30.09.2026

Ad Hoc News

also included Japanese microbiologists and collaborators from IST Austria and HZI Braunschweig (Germany), demonstrated that actin inhibitors

30.09.2026

Phys.org

for cell movement. Scientists from the Helmholtz Center for Infection Research (HZI) in Braunschweig have provided evidence that Profilin

29.09.2026

TakeToNews

Biology (BRICS), a joint research center of the Helmholtz Centre for Infection Research (HZI) and Technische Universität Braunschweig.

29.09.2026

Phys.org

... treffsicher .

Das Helmholtz-Zentrum für Infektionsforschung:

Wissenschaftler:innen am Helmholtz-Zentrum für Infektionsforschung (HZI) ...

28.09.2026

DeutschesGesundheitsPortal

... Fluorchinolon-Resistenz aktiv

Forscher des Helmholtz-Zentrums für Infektionsforschung (HZI) um Dr. Jennifer Herrmann haben ...

27.09.2026

scinexx - Das Wissensmagazin

Die WHO nennt Antibiotikaresistenzen (AMR) eine der größten globalen Gesundheitsbedrohungen. Bereits heute töten resistente Keime jährlich mehr als eine Million Menschen direkt und tragen zu fast fünf Millionen Todesfällen bei. Tendenz: steigend. Für ein wirkungsvolles Dagegenha

25.09.2026

Sysmex

... die Resistenzen": HZI-Podcast InFact mit Mark Brönstrup

Quelle: Helmholtz-Zentrum für Infektionsforschung (HZI)

Biodiversität ...

25.09.2026

Analytik NEWS

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