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Experts are increasingly turning to machine learning to predict antibiotic resistance in pathogens. With its help, resistance mechanisms can be identified based on a pathogen’s genetics. However, the results should be viewed with caution: Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg have shown that the models are often less reliable than assumed. Their findings were published in the journal PLOS Biology. They contribute to the development of more reliable tools for predicting and combating antibiotic resistance.

17.12.2025

HIRI

Teaser for the podcast with Andreas Keller

News

At first glance, biology and computer science seem like opposites. But wherever enormous amounts of data are generated from research, progress is hardly possible without digital methods. Bioinformatician Prof. Andreas Keller therefore relies on artificial intelligence. He heads the department “Clinical Bioinformatics” at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). In this episode of InFact, he talks about how AI can help us understand how beneficial and harmful bacteria communicate with each other in our bodies, how to predict when infections will cause long-term effects, and how this can be used to develop new drugs against dangerous pathogens.

16.12.2025

HIPS

News

Biphenomycins, natural products derived from bacteria, show excellent antimicrobial activity, but have long remained out of reach for drug development. The main obstacle was the limited understanding of how these compounds are produced by their microbial hosts. A research team led by Tobias Gulder, department head at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), has now deciphered the biosynthetic pathway of the biphenomycins, establishing the foundation for their pharmaceutical advancement. The team published its findings in the journal Angewandte Chemie International Edition.

11.12.2025

HIPS

Maximilian Order awarded to HIRI Director Jörg Vogel by Marcus Söder

News

On December 3, Jörg Vogel, Director of the Helmholtz Institute for RNA-based Infection Research, was honored with the Maximilian Order for Science and Art at a ceremony held in the Antiquarium of the Munich Residence. He received the distinction from Bavarian Minister-President Markus Söder, who referred to the Free State’s highest honor as the ‘Bavarian Nobel Prize’. HIRI is site of the Braunschweig Helmholtz Centre for Infection Research (HZI) in cooperation with the Julius-Maximilians-Universität Würzburg (JMU).

04.12.2025

HIRI

Story

On 18–20 November 2025, the Central African Republic (CAR) celebrated its first-ever Dzanga-Sangha Day (La Journée des Aires Protégées de Dzanga-Sangha). Conceived as a three-day national event, the celebration aimed to shine a spotlight on the country’s unique natural heritage and raise awareness of the Dzanga-Sangha Protected Areas (DSPA)—an extraordinary conservation landscape in CAR’s remote southwest. Held under the theme “Reconciling Nature, Health and Development”, the event underscored how biodiversity protection, community wellbeing, and scientific research intersect in DSPA. It was co-organized by the Government of the Central African Republic in partnership with WWF and the Helmholtz Institute for One Health (HIOH).

03.12.2025

HIOH

Group photo with 11 people behind a 3D lettering “HZI 60”

News

On November 27, 2025, the Helmholtz Centre for Infection Research (HZI) celebrated its 60th anniversary with a ceremony attended by cooperation partners, alumni, and guests from the worlds of science, politics, and industry. The research institution has been located on the Science Campus Braunschweig-Süd since 1965 and underwent several reorientations and renaming in the following decades. Among those offering their congratulations at the ceremony were Lower Saxony's Minister President Olaf Lies, the new President of the Helmholtz Association Prof. Martin Keller, and his predecessor and long-time companion of the HZI, Prof. Otmar D. Wiestler.

27.11.2025

HZI Campus

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HZI in the media

20.04.2026

World Organisation for Animal Health

20.04.2026

Springer

... Helmholtz-Zentrum für Infektionsforschung

02.09.2025 12:36

DLR Projektträger

02.10.2025 07:49 ...

17.04.2026

Informations Dienst Wissenschaft

Wissenschaftler des Max-Delbrück-Centrums und des Helmholtz-Zentrums für Infektionsforschung haben eine umfassende Protein-Karte von

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IT Boltwise

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Bionity.COM

In January 2023, researchers at the Helmholtz Institute for One Health in Germany noticed that an infant monkey known as a sooty mangabey

15.04.2026

New Atlas

at the Helmholtz Institute for RNA-based Infection Research (HIRI), a site of the Braunschweig Helmholtz Center for Infection Research (HZI)

14.04.2026

Phys.org

... der Infektion und Nozizeption“ am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig. Nozizeption ist der Fachbegriff ...

14.04.2026

Verband Deutscher Biologen e.V.

... recht nicht bei Fabian Leendertz, der in Greifswald das „Helmholtz-Institut für One Health“ leitet. Im ...

14.04.2026

FAZ.NET

... sich auch das Helmholtz-Institut für Pharmazeutische Forschung Saarland ( HIPS ), das Helmholtz-Zentrum für Infektionsforschung ( HZI ) ...

09.04.2026

Deutsches Ärzteblatt

... ÖAW in Wien und nun Gruppenleiter am Helmholtz Zentrum für Infektionsforschung in Braunschweig, forscht an ...

08.04.2026

DerStandard.de

... group within the Microstar Program at the Helmholtz Centre for Infection Research (HZI) and a ...

31.03.2026

Informations Dienst Wissenschaft

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