PD Dr. Frank Pessler

Sohail A., Waqas F.H., Braubach P., Czichon L., Samir M., Iqbal A., de Araujo L., Pleschka S., Steinert M., ... , Geffers R., Pessler F. (2024)

Differential transcriptomic host responses in the early phase of viral and bacterial infections in human lung tissue explants ex vivo

Respir.Res., 25 (1)

DOI: 10.1186/s12931-024-02988-8 HZI-Repositorium PubMed

Kumar S., Zoodsma M., Nguyen N., Pedroso R., Trittel S., Riese P., Botey-Bataller J., Zhou L., Alaswad A., Arshad H., Netea M.G., Xu C.J., Pessler F., Guzman C.A., ... , Graca L., Li Y. (2024)

Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population

Sci.Adv., 10 (39)

DOI: 10.1126/sciadv.adq7006 HZI-Repositorium PubMed

Neu F., Nay S., Schuchardt S., Klawonn F., Skripuletz T., ... , Suehs K.W., Pessler F. (2024)

Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens

Journal of Translational Medicine, 22 (1)

DOI: 10.1186/s12967-024-05422-1 HZI-Repositorium PubMed

Waqas F.H., Chen C., Pessler F. (2024)

Aconitate decarboxylase (ACOD1) has found a disease

Trends in Endocrinology and Metabolism, 35 (7)

DOI: 10.1016/j.tem.2024.04.003 PubMed

Al-Mekhlafi A., Waqas F.H., Krueger M., Klawonn F., Akmatov M.K., Müller-Vahl K., Trebst C., Skripuletz T., Stangel M., ... , Sühs K.W., Pessler F. (2023)

Elevated phospholipids and acylcarnitines C4 and C5 in cerebrospinal fluid distinguish viral CNS infections from autoimmune neuroinflammation

J.Transl.Med., 21 (1)

DOI: 10.1186/s12967-023-04637-y HZI-Repositorium PubMed

Akmatov M.K., Beisheeva N.J., Nurmatov A.Z., Gulsunai S.J., Saikal K.N., Derkenbaeva A.A., Abdrahmanova Z.O., Prokein J., Klopp N., Illig T., Kasymov O.T., ... , Nurmatov Z.S., Pessler F. (2023)

The Changing Epidemiology of Viral Hepatitis in a Post-Soviet Country-The Case of Kyrgyzstan

Pathogens., 12 (8)

DOI: 10.3390/pathogens12080989 HZI-Repositorium PubMed

Waqas F.H., Shehata M., Elgaher W.A.M., Lacour A., Kurmasheva N., Begnini F., Kiib A.E., Dahlmann J., Chen C., Pavlou A., Poulsen T.B., Merkert S., Martin U., Olmer R., Olagnier D., Hirsch A.K.H., ... , Pleschka S., Pessler F. (2023)

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

PLoS.Pathog., 19 (7)

DOI: 10.1371/journal.ppat.1011506 HZI-Repositorium PubMed

Chen F., Yalcin I., Zhao M., Chen C., Blankenfeldt W., ... , Pessler F., Büssow K. (2023)

Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1

Sci.Rep., 13 (1)

DOI: 10.1038/s41598-023-37373-w HZI-Repositorium PubMed

Merkert S., Haase A., Dahlmann J., Göhring G., Waqas F.H., Pessler F., ... , Martin U., Olmer R. (2023)

Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing

Stem Cell Research, 69 (June 2023)

DOI: 10.1016/j.scr.2023.103090 HZI-Repositorium PubMed

Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A. (2022)

Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-34487-z HZI-Repositorium PubMed

Arshad H., Siokis A., Franke R., Habib A., Alfonso J.C.L., Poliakova Y., Lücke E., Michaelis K., Brönstrup M., Meyer-Hermann M., Bilitewski U., Vila J., Abel L., Illig T., ... , Schreiber J., Pessler F. (2022)

Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease

Cells, 11 (15)

DOI: 10.3390/cells11152283 HZI-Repositorium PubMed

Waqas S.F., Sohail A., Nguyen A.H.H., Usman A., Ludwig T., Wegner A., Malik M.N.H., Schuchardt S., Geffers R., Winterhoff M., Merkert S., Martin U., Olmer R., ... , Lachmann N., Pessler F. (2022)

ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives

Clin.Transl.Med., 12 (7)

DOI: 10.1002/ctm2.931 HZI-Repositorium PubMed

Gruenwald M., Chen F., Bähre H., Pessler F. (2022)

Itaconate Isomers in Bread

Antioxidants.(Basel), 11 (7)

DOI: 10.3390/antiox11071382 HZI-Repositorium PubMed

Chen F., Elgaher W.A.M., Winterhoff M., Büssow K., Waqas F.H., Graner E., Pires-Afonso Y., Casares Perez L., La Vega L., Sahini N., Czichon L., Zobl W., Zillinger T., Shehata M., Pleschka S., Bähre H., Falk C., Michelucci A., Schuchardt S., Blankenfeldt W., ... , Hirsch A.K.H., Pessler F. (2022)

Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism

Nat.Metab, 4 (5)

DOI: 10.1038/s42255-022-00577-x HZI-Repositorium PubMed

Sohail A., Iqbal A.A., Sahini N., Chen F., Tantawy M., Waqas F., Winterhoff M., Ebensen T., Schultz K., Geffers R., Schughart K., Preusse M., Shehata M., Bähre H., Pils M.C., Guzmán C.A., Mostafa A., Pleschka S., Falk C., ... , Michelucci A., Pessler F. (2022)

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

PLoS Pathog., 18 (1)

DOI: 10.1371/journal.ppat.1010219 HZI-Repositorium PubMed

Malik M.N.H., Waqas S.F.H., Zeitvogel J., Cheng J., Geffers R., Gouda Z.A., Elsaman A.M., Radwan A.R., Schefzyk M., Braubach P., Auber B., Olmer R., Müsken M., Roesner L.M., Gerold G., Schuchardt S., Merkert S., Martin U., Meissner F., ... , Werfel T., Pessler F. (2021)

Congenital deficiency reveals critical role of ISG15 in skin homeostasis

J.Clin.Invest

DOI: 10.1172/JCI141573 HZI-Repositorium PubMed

de Araujo L.S., Ribeiro-Alves M., Wipperman M.F., Vorkas C.K., Pessler F., Saad M.H.F. (2021)

Transcriptomic biomarkers for tuberculosis: Validation of npc2 as a single mrna biomarker to diagnose tb, predict disease progression, and monitor treatment response

Cells, 10 (10)

DOI: 10.3390/cells10102704 HZI-Repositorium PubMed

Luo Y., Möhn N., Skripuletz T., Senel M., Tumani H., Pessler F., ... , Sühs K.W., Stangel M. (2021)

Differentiation of viral and autoimmune central nervous system inflammation by kynurenine pathway

Ann.Clin.Transl.Neurol.

DOI: 10.1002/acn3.51383 HZI-Repositorium PubMed

Ramli S.R., Bunk B., Spröer C., Geffers R., Jarek M., Bhuju S., Goris M., ... , Mustakim S., Pessler F. (2021)

Complete genome sequencing of leptospira interrogans isolates from malaysia reveals massive genome rearrangement but high conservation of virulence-associated genes

Pathogens, 10 (9)

DOI: 10.3390/pathogens10091198 HZI-Repositorium PubMed

Al-Mekhlafi A., Sühs K.W., Schuchardt S., Kuhn M., Müller-Vahl K., Trebst C., Skripuletz T., Klawonn F., ... , Stangel M., Pessler F. (2021)

Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections

Cells, 10 (5)

DOI: 10.3390/cells10051115 HZI-Repositorium PubMed

Franz S., Pott F., Zillinger T., Schüler C., Dapa S., Fischer C., Passos V., Stenzel S., Chen F., Döhner K., Hartmann G., Sodeik B., Pessler F., Simmons G., ... , Drexler J.F., Goffinet C. (2021)

Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction

Life Sci.Alliance., 4 (7)

DOI: 10.26508/lsa.202000909 HZI-Repositorium PubMed

Winterhoff M., Chen F., Sahini N., Ebensen T., Kuhn M., Kaever V., ... , Bähre H., Pessler F. (2021)

Establishment, validation, and initial application of a sensitive lc-ms/ms assay for quantification of the naturally occurring isomers itaconate, mesaconate, and citraconate

Metabolites., 11 (5)

DOI: 10.3390/metabo11050270 HZI-Repositorium PubMed

Merkert S., Jaboreck M.C., Engels L., Malik M.N.H., Göhring G., Pessler F., ... , Martin U., Olmer R. (2020)

Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing

Stem Cell Res., 50 (January 2021)

DOI: 10.1016/j.scr.2020.102135 HZI-Repositorium PubMed

Kreißl S., Hendler S., Akmatov M.K., von Meien M., Range U., ... , Pessler F., Vogelberg C. (2021)

Reduced Exhaled Breath Condensate pH and Severity of Allergic Sensitization Predict School Age Asthma

J.Allergy Clin.Immunol.Pract.

DOI: 10.1016/j.jaip.2020.10.058

Luo Y., Möhn N., Al-Mekhlafi A., Schuchardt S., Skripuletz T., Sühs W., ... , Pessler F., Stangel M. (2020)

Targeted metabolomic profiling of cerebrospinal fluid from patients with progressive multifocal leukoencephalopathy

PLoS.ONE., 15 (11)

DOI: 10.1371/journal.pone.0242321 HZI-Repositorium PubMed

Martin-Fernandez M., Bravo Garcia-Morato M., Gruber C., Murias Loza S., Malik M.N.H., Alsohime F., Alakeel A., Valdez R., Buta S., Buda G., Marti M.A., Larralde M., Boisson B., Feito Rodriguez M., Qiu X., Chrabieh M., Al Ayed M., Al Muhsen S., Desai J.V., Ferre E.M.N., Rosenzweig S.D., Amador-Borrero B., Bravo-Gallego L.Y., Olmer R., Merkert S., Bret M., Sood A.K., Al-Rabiaah A., Temsah M.H., Halwani R., Hernandez M., Pessler F., Casanova J.L., Bustamante J., ... , Lionakis M.S., Bogunovic D. (2020)

Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions

Cell Rep., 31 (6)

DOI: 10.1016/j.celrep.2020.107633 PubMed

Hahn K., Pollmann L., Nowak J., Nguyen A.H.H., Haake K., Neehus A.L., Waqas S.F.H., Pessler F., Baumann U., Hetzel M., Casanova J.L., Schulz A., Bustamante J., ... , Ackermann M., Lachmann N. (2020)

Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-g[gamma]R1 Deficiency

Mol.Ther.Methods Clin.Dev., 17

DOI: 10.1016/j.omtm.2020.04.002 HZI-Repositorium PubMed

Freuer D., Linseisen J., Waterboer T., Pessler F., Guzmán C.A., Wawro N., ... , Peters A., Meisinger C. (2020)

Seropositivity of selected chronic infections and different measures of obesity

PLoS.ONE., 15 (4)

DOI: 10.1371/journal.pone.0231974 HZI-Repositorium PubMed

Reinke S., Linge M., Diebner H.H., Luksch H., Glage S., Gocht A., Robertson A.A.B., Cooper M.A., Hofmann S.R., Naumann R., Sarov M., Behrendt R., Roers A., Pessler F., Roesler J., ... , Rösen-Wolff A., Winkler S. (2020)

Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-a[alpha]-Mediated Inflammation In Vivo

Cell Rep., 30 (8)

DOI: 10.1016/j.celrep.2020.01.090 HZI-Repositorium PubMed

de Araujo L.S., Pessler K., Suhs K.W., Novoselova N., Klawonn F., Kuhn M., Kaever V., Muller-Vahl K., Trebst C., Skripuletz T., ... , Stangel M., Pessler F. (2020)

Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis

J.Transl.Med., 18 (1)

DOI: 10.1186/s12967-019-02179-w HZI-Repositorium PubMed

de Araujo L.S., Ribeiro-Alves M., Leal-Calvo T., Leung J., Duran V., Samir M., Talbot S., Tallam A., Mello F.C.Q., Geffers R., ... , Saad M.H.F., Pessler F. (2019)

Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection

MBio., 10 (6)

DOI: 10.1128/mBio.01037-19 HZI-Repositorium PubMed

Arshad H., Alfonso J.C.L., Franke R., Michaelis K., Araujo L., Habib A., Zboromyrska Y., Lucke E., Strungaru E., Akmatov M.K., Hatzikirou H., Meyer-Hermann M., Petersmann A., Nauck M., Brönstrup M., Bilitewski U., Abel L., Sievers J., Vila J., Illig T., ... , Schreiber J., Pessler F. (2019)

Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia

J.Transl.Med., 17 (1)

DOI: 10.1186/s12967-019-2112-z HZI-Repositorium PubMed

Samir M., Vidal R.O., Abdallah F., Capece V., Seehusen F., Geffers R., Hussein A., Ali A.A.H., ... , Bonn S., Pessler F. (2020)

Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1)

RNA.Biol., 17 (1)

DOI: 10.1080/15476286.2019.1669879 PubMed

Chen F., Lukat P., Iqbal A.A., Saile K., Kaever V., van den Heuvel J., Blankenfeldt W., ... , Büssow K., Pessler F. (2019)

Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis

Proc.Natl.Acad.Sci.U.S.A, 116 (41)

DOI: 10.1073/pnas.1908770116 HZI-Repositorium PubMed

Akmatov M.K., Riese P., Trittel S., May M., Prokein J., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2019)

Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly

BMC Infect.Dis., 19 (1)

DOI: 10.1186/s12879-019-4214-x HZI-Repositorium PubMed

Wawro N., Aman U., Butt J., Meisinger C., Akmatov M.K., Pessler F., Peters A., Rathmann W., Kääb S., ... , Waterboer T., Linseisen J. (2019)

Helicobacter pylori seropositivity: Prevalence, associations and the impact on incident metabolic diseases/risk factors in the population-based KORA study

Frontiers in Public Health, 7 (Apr.)

DOI: 10.3389/fpubh.2019.00096 HZI-Repositorium PubMed

Sühs K.W., Novoselova N., Kuhn M., Seegers L., Kaever V., Müller-Vahl K., Trebst C., Skripuletz T., ... , Stangel M., Pessler F. (2019)

Kynurenine is a cerebrospinal fluid biomarker for bacterial and viral CNS infections

J.Infect.Dis., 220 (1)

DOI: 10.1093/infdis/jiz048 HZI-Repositorium PubMed

Ramli S.R., Moreira G.M.S.G., Zantow J., Goris M.G.A., Nguyen V.K., Novoselova N., ... , Pessler F., Hust M. (2019)

Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display

PLoS Negl.Trop.Dis., 13 (1)

DOI: 10.1371/journal.pntd.0007131 HZI-Repositorium PubMed

Ratuszny D., Sühs K.W., Novoselova N., Kuhn M., Kaever V., Skripuletz T., ... , Pessler F., Stangel M. (2019)

Identification of Cerebrospinal Fluid Metabolites as Biomarkers for Enterovirus Meningitis

Int J Mol Sci, 20 (2)

DOI: 10.3390/ijms20020337 HZI-Repositorium PubMed

Chen Y.L., Jing J., Mo Y.Q., Ma J.D., Yang L.J., Chen L.F., Zhang X., Yan T., Zheng D.H., ... , Pessler F., Dai L. (2018)

Presence of hepatitis B virus in synovium and its clinical significance in rheumatoid arthritis

Arthritis Res.Ther., 20 (1)

DOI: 10.1186/s13075-018-1623-y HZI-Repositorium PubMed

Strehlitz A., Goldmann O., Pils M.C., Pessler F., Medina E. (2018)

An interferon signature discriminates pneumococcal from staphylococcal pneumonia

Front.Immunol., 9 (JUN)

DOI: 10.3389/fimmu.2018.01424 HZI-Repositorium PubMed

Olmer R., Engels L., Usman A., Menke S., Malik M.N.H., Pessler F., Göhring G., Bornhorst D., Bolten S., Abdelilah-Seyfried S., Scheper T., Kempf H., ... , Zweigerdt R., Martin U. (2018)

Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture

Stem Cell Rep., 10 (5)

DOI: 10.1016/j.stemcr.2018.03.017 HZI-Repositorium PubMed

Petersen H., Mostafa A., Tantawy M.A., Iqbal A.A., Hoffmann D., Tallam A., Selvakumar B., Pessler F., Beer M., ... , Rautenschlein S., Pleschka S. (2018)

NS segment of a 1918 influenza a virus-descendent enhances replication of H1N1pdm09 and virus-induced cellular immune response in mammalian and avian systems

Front.Microbiol., 9 (MAR)

DOI: 10.3389/fmicb.2018.00526 HZI-Repositorium PubMed

Loof T.G., Sohail A., Bahgat M.M., Tallam A., Arshad H., Akmatov M.K., Pils M.C., Heise U., ... , Beineke A., Pessler F. (2018)

Early lymphocyte loss and increased granulocyte/lymphocyte ratio predict systemic spread of Streptococcus pyogenes in a mouse model of acute skin infection

Front.Cell.Infect.Microbiol., 8 (APR)

DOI: 10.3389/fcimb.2018.00101 HZI-Repositorium

Kuhn M., Sühs K.W., Akmatov M.K., Klawonn F., Wang J., Skripuletz T., Kaever V., ... , Stangel M., Pessler F. (2018)

Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation

J.Neuroinflammation., 15 (1)

DOI: 10.1186/s12974-017-1041-0 HZI-Repositorium PubMed

Samir M., Hamed M., Abdallah F., Kinh Nguyen V, Hernandez-Vargas E.A., Seehusen F., Baumgartner W., Hussein A., ... , Ali A.A.H., Pessler F. (2018)

An Egyptian HPAI H5N1 isolate from clade 2.2.1.2 is highly pathogenic in an experimentally infected domestic duck breed (Sudani duck)

Transbound.Emerg.Dis., 65 (3)

DOI: 10.1111/tbed.12816 HZI-Repositorium PubMed

Filomena A., Pessler F., Akmatov M.K., Krause G., Duffy D., Gerhard M., ... , Albert M.L., Joos T.O. (2017)

Development of a bead-based multiplex assay for the analysis of the serological response against the six pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori

High Throughput, 6 (4)

DOI: 10.3390/ht6040014 HZI-Repositorium

Krenn V., Perino G., Ruther W., Krenn V.T., Huber M., Hugle T., Najm A., Muller S., Boettner F., Pessler F., Waldstein W., Kriegsmann J., Casadonte R., Haupl T., Wienert S., Krukemeyer M.G., Sesselmann S., Sunitsch S., ... , Tikhilov R., Morawietz L. (2017)

15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics

Pathol.Res.Pract.

DOI: 10.1016/j.prp.2017.05.005 PubMed

Akmatov M.K., Rober N., Ahrens W., Flesch-Janys D., Fricke J., Greiser H., Gunther K., Kaaks R., Kemmling Y., Krone B., Linseisen J., Meisinger C., Moebus S., Obi N., Guzmán C.A., ... , Conrad K., Pessler F. (2017)

Anti-nuclear autoantibodies in the general German population: prevalence and lack of association with selected cardiovascular and metabolic disorders-findings of a multicenter population-based study

Arthritis Res.Ther., 19 (1)

DOI: 10.1186/s13075-017-1338-5 HZI-Repositorium PubMed

Pessler F., Sherry D.D. (2011)

Rheumatic Fever

, 20th

DOI: - PubMed

Krenn V., Perino G., Ruther W., Krenn V.T., Huber M., Hugle T., Najm A., Muller S., Boettner F., Pessler F., Waldstein W., Kriegsmann J., Haupl T., Wienert S., Krukemeyer M.G., Sesselmann S., ... , Tikhilov R., Morawietz L. (2017)

[Fifteen years of the histopathological synovitis score : Review and further developments of a diagnostic score]

Z.Rheumatol., 76 (6)

DOI: 10.1007/s00393-017-0308-2 PubMed

Akmatov M.K., Koch N., Vital M., Ahrens W., Flesch-Janys D., Fricke J., Gatzemeier A., Greiser H., Gunther K., Illig T., Kaaks R., Krone B., Kuhn A., Linseisen J., Meisinger C., Michels K., Moebus S., Nieters A., Obi N., Schultze A., Six-Merker J., ... , Pieper D.H., Pessler F. (2017)

Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study - findings from Pretest 1 of the German National Cohort

Sci.Rep., 7 (1)

DOI: 10.1038/s41598-017-01212-6 HZI-Repositorium PubMed

Preusse M., Schughart K., Wilk E., Klawonn F., Pessler F. (2015)

Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains Infectious Diseases

BMC Res.Notes, 8 (1)

DOI: 10.1186/s13104-015-1195-8 HZI-Repositorium PubMed

Schweitzer A., Pessler F., Akmatov M.K. (2016)

Impact of rotavirus vaccination on coverage and timing of pentavalent vaccination - Experience from 2 Latin American countries

Hum.Vaccines Immunother., 12 (5)

DOI: 10.1080/21645515.2015.1127486 HZI-Repositorium PubMed

Preusse M., Schughart K., Pessler F. (2017)

Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection

Front Immunol., 8

DOI: 0.3389/fimmu.2017.00246 HZI-Repositorium PubMed

Akmatov M.K., Riese P., May M., Jentsch L., Ahmed M.W., Werner D., Rosel A., Tyler M., Pessler K., Prokein J., Bernemann I., Klopp N., Prochnow B., Trittel S., Tallam A., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2017)

Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population

Hum.Vaccin.Immunother.

DOI: 10.1080/21645515.2017.1299300 HZI-Repositorium PubMed

Karabaev B.B., Beisheeva N.J., Satybaldieva A.B., Ismailova A.D., Pessler F., Akmatov M.K. (2017)

Seroprevalence of hepatitis B, hepatitis C, human immunodeficiency virus, Treponema pallidum, and co-infections among blood donors in Kyrgyzstan: a retrospective analysis (2013-2015)

Infect.Dis.Poverty., 6 (1)

DOI: 10.1186/s40249-017-0255-9 HZI-Repositorium PubMed

Akmatov M.K., Jentsch L., Riese P., May M., Ahmed M.W., Werner D., Rösel A., Prokein J., Bernemann I., Klopp N., Prochnow B., Illig T., Schindler C., ... , Guzmán C.A., Pessler F. (2017)

Motivations for (non)participation in population-based health studies among the elderly - comparison of participants and nonparticipants of a prospective study on influenza vaccination

BMC Med.Res.Methodol., 17 (1)

DOI: 10.1186/s12874-017-0302-z HZI-Repositorium PubMed

Samir M., Vaas L.A., Pessler F. (2016)

MicroRNAs in the Host Response to Viral Infections of Veterinary Importance

Front Vet.Sci, 3 (Oct)

DOI: 10.3389/fvets.2016.00086 HZI-Repositorium PubMed

de Araujo L.S., Vaas L.A., Ribeiro-Alves M., Geffers R., Mello F.C., de Almeida A.S., Moreira A.D., Kritski A.L., Lapa E Silva JR, Moraes M.O., ... , Pessler F., Saad M.H. (2016)

Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood

Front Microbiol., 7 (Oct)

DOI: 10.3389/fmicb.2016.01586 HZI-Repositorium PubMed

Hendel N., Akmatov M.K., Hamel J., Vogelberg C., Pessler F. (2016)

Exhaled breath analysis in childhood rheumatic disorders - A longitudinal study

J.Breath Res., 10 (2)

DOI: 10.1088/1752-7155/10/2/021001 HZI-Repositorium PubMed

Akmatov M.K., Stumme M., Pessler F. (2016)

Real-life practice of methotrexate toxicity monitoring in juvenile idiopathic arthritis in Germany, Switzerland and Austria: results of a cross-sectional assessment conducted in 2012

Clin.Exp.Rheumatol., 34 (3)

DOI: - HZI-Repositorium PubMed

Samir M., Pessler F. (2016)

Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications

Front Vet.Sci, 3

DOI: 10.3389/fvets.2016.00022 HZI-Repositorium PubMed

Elsaman A.M., Muhammad E.M., Pessler F. (2016)

Sonographic Findings in Gouty Arthritis: Diagnostic Value and Association with Disease Duration

Ultrasound Med.Biol., 42 (6)

DOI: 10.1016/j.ultrasmedbio.2016.01.014 PubMed

Schlett C.L., Hendel T., Hirsch J., Weckbach S., Caspers S., Schulz-Menger J., Ittermann T., von Knobelsdorff-Brenkenhoff F., Ladd S.C., Moebus S., Stroszczynski C., Fischer B., Leitzmann M., Kuhl C., Pessler F., Hartung D., Kemmling Y., Hetterich H., Amunts K., Gunther M., Wacker F., Rummeny E., Kauczor H.U., Forsting M., Völzke H., Hosten N., ... , Reiser M.F., Bamberg F. (2015)

Quantitative, Organ-Specific Interscanner and Intrascanner Variability for 3 T Whole-Body Magnetic Resonance Imaging in a Multicenter, Multivendor Study

Invest Radiol., 51 (4)

DOI: 10.1097/RLI.0000000000000237 PubMed

Akmatov M.K., Rubsamen N., Schultze A., Kemmling Y., Obi N., Günther K., Ahrens W., Pessler F., ... , Krause G., Mikolajczyk R.T. (2015)

Diverse recruitment strategies result in different participation percentages in a web-based study, but in similar compliance

Int.J Public Health, 60 (8)

DOI: 10.1007/s00038-015-0737-0 PubMed

Schweitzer A., Akmatov M.K., Kindler F., Kemmling Y., Kreienbrock L., ... , Krause G., Pessler F. (2015)

The impact of distance and duration of travel on participation rates and participants' satisfaction: results from a pilot study at one study centre in Pretest 2 of the German National Cohort

BMJ Open., 5 (8)

DOI: 10.1136/bmjopen-2014-007461 HZI-Repositorium PubMed

Schweitzer A., Krause G., Pessler F., Akmatov M.K. (2015)

Improved coverage and timing of childhood vaccinations in two post-Soviet countries, Armenia and Kyrgyzstan

BMC Public Health, 15 (1)

DOI: 10.1186/s12889-015-2091-9 HZI-Repositorium PubMed

Schweitzer A., Della Beffa C., Akmatov M.K., Narchi H., Abaev Y.K., ... , Sherry D.D., Pessler F. (2015)

Primary Osteomyelitis of the Sternum in the Pediatric Age Group: Report of a New Case and Comprehensive Analysis of Seventy-four Cases

Pediatr.Infect.Dis.J, 34 (4)

Mall S., Akmatov M.K., Schultze A., Ahrens W., Obi N., ... , Pessler F., Krause G. (2014)

Web-based questionnaires to capture acute infections in long-term cohorts : Findings of a feasibility study

Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Akmatov M.K., Mehraj J., Gatzemeier A., Strömpl J., Witte W., ... , Krause G., Pessler F. (2015)

Erratum to 'Serial home-based self-collection of anterior nasal swabs to detect Staphylococcus aureus carriage in a randomized population-based study in Germany'. [International Journal of Infectious Diseases (2014) 4-10, doi:10.1016/j.ijid.2014.01.021]

Int.J.Infect.Dis., 30

Akmatov M.K., Kimani-Murage E., Pessler F., Guzmán C.A., Krause G., ... , Kreienbrock L., Mikolajczyk R.T. (2014)

Evaluation of invalid vaccine doses in 31 countries of the WHO African Region

Vaccine, 33

Kuhn A., Nieters A., Kottgen A., Goek O.N., Michels K., Nothlings U., Jacobs G., Meisinger C., Pessler Frank, Akmatov M.K., Kuhnisch J., Moebus S., Glocker E., Naus S., Keimling M., Leitzmann M., Linseisen J., Sarioglu H., von Toerne C., Hauck S.M., Wallaschofski H., ... , Wichmann H.E., Illig T. (2014)

Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort

Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Castell S., Akmatov M.K., Obi N., Flesh-Janys D., Nieters A., Kemmling Y., ... , Pessler F., Krause G. (2014)

Test-retest reliability of an infectious disease questionnaire and evaluation of self-assessed vulnerability to infections : Findings of Pretest 2 of the German National Cohort

Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Schultze A., Akmatov M.K., Castell S., Karch A., Ahrens W., Gunther K., Schlenz H., Flesch-Janys D., Obi N., ... , Pessler F., Krause G. (2014)

Collection of vaccination data in the German National Cohort : Findings of a feasibility study in three study centers

Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Schultze A., Akmatov M.K., Andrzejak M., Karras N., Kemmling Y., Maulhardt A., Wieghold S., Ahrens W., Gunther K., Schlenz H., ... , Krause G., Pessler F. (2014)

Comparison of stool collection on site versus at home in a population-based study : Feasibility and participants' preference in Pretest 2 of the German National Cohort

Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

Sievers C., Akmatov M.K., Kreienbrock L., Hille K., Ahrens W., Gunther K., Flesch-Janys D., Obi N., Michels K.B., Fricke J., Greiser K.H., Kaaks R., Peter H.H., Pessler F., ... , Nieters A., Krause G. (2014)

Evaluation of a questionnaire to assess selected infectious diseases and their risk factors : Findings of a multicenter study

Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz., 57 (11)

DOI: 10.1007/s00103-014-2052-y HZI-Repositorium PubMed

Mehraj J., Akmatov M.K., Strömpl J., Gatzemeier A., Layer F., Werner G., Pieper D.H., Medina E., Witte W., ... , Pessler F., Krause G. (2014)

Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus Nasal Carriage in a Random Sample of Non-Hospitalized Adult Population in Northern Germany

PLoS ONE, 9 (9)

DOI: 10.1371/journal.pone.0107937 HZI-Repositorium PubMed

Akmatov M.K., Mehraj J., Gatzemeier A., Strömpl Julia, Witte W., ... , Krause G., Pessler F. (2014)

Serial home-based self-collection of anterior nasal swabs to detect Staphylococcus aureus carriage in a randomized population-based study in Germany

International Journal of Infectious Diseases, 25

DOI: 10.1016/j.ijid.2014.01.021 HZI-Repositorium PubMed

Novoselova N., Della Beffa Cristina, Wang Junxi, Li J., Pessler Frank, Klawonn Frank (2014)

HUM calculator and HUM package for R: easy-to-use software tools for multicategory receiver operating characteristic analysis

Bioinformatics, 30 (11)

Preusse M., Tantawy M.A., Klawonn F., Schughart K., Pessler F. (2013)

Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice

BMC Microbiology, 13 (1)

Pessler Frank, Ogdie A.R., Mayer C.T., Kretzschmar W.W., Dai L., Elsaman A.M., Einhorn E., ... , Krenn V., Schumacher H.R. (2014)

Amyloid arthropathy associated with multiple myeloma: polyarthritis without synovial infiltration of CD20+ or CD38+ cells

Amyloid, 21

DOI: 10.3109/13506129.2013.862229 HZI-Repositorium PubMed

Elsaman A.M., Radwan A.R., Akmatov M.K., Della Beffa C., Walker A., Mayer C.T., Dai L., Nativ S., Rygg M., Atsali E., Saijo K., Ogdie A.R., Srinivasulu N., Fathi N., ... , Schumacher H.R., Pessler F. (2013)

Amyloid arthropathy associated with multiple myeloma: A systematic analysis of 101 reported cases

Seminars in Arthritis and Rheumatism, 43 (3)

Klawonn F., Jayaram B., Crull K., Kukita A., Pessler F. (2013)

Analysis of contingency tables based on generalized median polish with power transformations and non-additive models

Health Information Science & Systems, 1

DOI: 10.1186/2047-2501-1-11 HZI-Repositorium PubMed

Akmatov M.K., Mikolajczyk R.T., Krumkamp R., Wörmann T., Chu J.J., Paetzelt G., Reintjes R., ... , Pessler F., Krämer A. (2012)

Availability of indicators of migration in the surveillance of HIV, tumberculosis and hepatitis B in the European Union - a short note

Journal of Public Health, 20

Della Beffa Cristina, Slansky E., Pommerenke C., Klawonn Frank, Li J., Dai L., ... , Schumacher H.R. Jr., Pessler Frank (2013)

The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification

PLoS ONE, 8 (8)

DOI: 10.1371/journal.pone.0072494 HZI-Repositorium PubMed

Zou C.J., Zhu L.J., Li Y.H., Mo Y.Q., Zheng D.H., Ma J.D., Ou-Yang X., ... , Pessler Frank, Dai L. (2013)

The association between hepatitis B virus infection and disease activity, synovitis, or joint destruction in rheumatoid arthritis

Clinical Rheumatology, 32 (6)

Luksch H., Romanowski M.J., Chara O., Tungler V., Caffarena E.R., Heymann M.C., Lohse P., Aksentijevich I., Remmers E.F., Flecks S., Quoos N., Gramatte J., Petzold C., Hofmann S.R., Winkler S., Pessler F., Kallinich T., Ganser G., Nimtz-Talaska A., Baumann U., Runde V., Grimbacher B., Birmelin J., Gahr M., ... , Roesler J., Rosen-Wolff A. (2013)

Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1b[beta]

Human Mutation, 34 (1)

DOI: 10.1002/humu.22169 PubMed

Akmatov M.K., Gatzemeier Anja, Schughart Klaus, Pessler Frank (2012)

Equivalence of self- and staff-collected nasal swabs for the detection of viral respiratory pathogens

PLoS ONE, 7 (11)

DOI: 10.1371/journal.pone.0048508 HZI-Repositorium PubMed

Akmatov M.K., Pessler F. (2011)

Self-collected nasal swabs to detect infection and colonization: a useful tool for population-based epidemiological studies?3356

International Journal of Infectious Diseases, 15 (9)

DOI: 10.1016/j.ijid.2011.04.009 HZI-Repositorium PubMed

Klawonn Frank, Crull Katja, Kukita A., Pessler Frank (2012)

Median polish with power transformations as an alternative for the analysis of contingency tables with patient data

LNCS (Lecture Notes in Computer Sience (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)), 7231

Winkler S., Dai L., Hauck F., Dinger J., Pessler Frank (2012)

Primary osteomyelitis of the clavicle in the newborn period

Pediatric Infectious Disease Journal, 31 (2)

Della Beffa Cristina*, Klawonn Frank*, Menetski J.P., Schumacher H.R., Pessler Frank* (2011)

Evaluation of glyceraldehyde-3-phosphate, prolylpeptidyl isomerase A, and a set of stably expressed genes as reference mRNAs in urate crystal inflammation

BMC Research Notes, 4

DOI: 10.1186/1756-0500-4-443 HZI-Repositorium

Mo Y.Q., Dai L., Zheng D.H., Zhu L.J., Wei X.N., Pessler Frank*, ... , Shen J., Zhang B.Y. (2011)

Synovial Infiltration with CD79a-positive B Cells, But Not Other B Cell Lineage Markers, Correlates with Joint Destruction in Rheumatoid Arthritis

Journal of Rheumatology, 38 (11)

Akmatov M.K., Krebs S., Preusse M., Gatzemeier A., Frischmann U., ... , Schughart Klaus*, Pessler F. (2011)

E-mail-based symptomatic surveillance combined with self-collection of nasal swabs: a new tool for acute respiratory infection epidemiology

International Journal of Infectious Diseases, 15 (11)

Kukita A., Kukita T., Nagata K., Teramachi J., Li Y.J., Yoshida H., Miyamoto H., Gay S., ... , Pessler Frank*, Shobuike T. (2011)

The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo

Arthritis and Rheumatism, 63 (9)

DOI: 10.1002/art.30455 HZI-Repositorium PubMed

von Jagwitz M., Pessler F., Akmatov M.K., Range U., Vogelberg C. (2011)

Reduced breath condensate pH in asymptomatic children with prior wheezing as a risk factor for asthma

Journal of Allergy and Clinical Immunology, 128 (1)

DOI: 10.1016/j.jaci.2011.03.005 HZI-Repositorium PubMed

Dai L., Wei X.N., Zheng D.H., Mo Y.Q., Pessler Frank*, Zhang B.Y. (2011)

Effective treatment of Kimura's disease with leflunomide in combination with glucocorticoids

Clinical Rheumatology, 30 (6)

Hauck F., Lee-Kirsch M.A., Aust D., Roesler J., Pessler Frank* (2010)

Complement C2 deficiency disarranging innate and adaptive humoral immune responses in a pediatric patient: Treatment with rituximab

Arthritis Care Res (Hoboken.), 63 (3)

DOI: 10.1002/acr.20361 HZI-Repositorium PubMed

Gemulla G., Pessler Frank* (2011)

Can Norovirus Infection Lead to a Postinfectious Arthritis? Report of 2 Possible Cases

Klinische Pädiatrie, 223 (1)

Bruck N., Suttorp M., Kabus M., Heubner G., Gahr M., Pessler Frank* (2011)

Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids

Journal of Clinical Rheumatology, 17 (1)

Slansky E., Li J., Haupl T., Morawietz L., Krenn V., Pessler Frank* (2010)

Quantitative determination of the diagnostic accuracy of the synovitis score and its components

Histopathology, 57 (3)

DOI: 10.1111/j.1365-2559.2010.03641.x HZI-Repositorium PubMed

Ogdie A., Schumacher H.R. Jr., Dai L., Chen L.X., Einhorn E., Pessler Frank* (2010)

Synovial biopsy findings in arthritis associated with hepatitis C virus infection

Journal of Rheumatology, 37 (6)

Bruck N., Gahr M., Pessler F. (2010)

Transient oligoarthritis of the lower extremity following influenza B virus infection: Case report

Pediatric Rheumatology, 8

DOI: 10.1186/1546-0096-8-4 HZI-Repositorium PubMed

Ogdie A., Li J., Dai L., Paessler M.E., Yu X., az-Torne C., Akmatov M.K., ... , Schumacher H.R., Pessler F. (2010)

Identification of broadly discriminatory tissue biomarkers of synovitis with binary and multicategory receiver operating characteristic analysis

Biomarkers, 15 (2)

PD Dr Frank Pessler

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