Prof. Dr. Dr. h.c. Dirk Heinz

Groenewold M.K., Hebecker S., Fritz C., Czolkoss S., Wiesselmann M., Heinz D.W., Jahn D., Narberhaus F., ... , Aktas M., Moser J. (2019)

Virulence of Agrobacterium tumefaciens requires lipid homeostasis mediated by the lysyl-phosphatidylglycerol hydrolase AcvB

Mol.Microbiol., 111 (1)

DOI: 10.1111/mmi.14154 HZI-Repositorium PubMed

Groenewold M.K., Massmig M., Hebecker S., Danne L., Magnowska Z., Nimtz M., Narberhaus F., Jahn D., Heinz D.W., ... , Jänsch L., Moser J. (2018)

A phosphatidic acid binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa

Biochem.J., 475 (11)

DOI: 10.1042/BCJ20180257

Stadler M., Dersch P., Heinz D. (2017)

Preface

DOI: - PubMed

Debarry J., Heinz D., Manns M.P. (2017)

[Individualized infection medicine : Challenges and opportunities] Individualisierte Infektionsmedizin :Herausforderungen und Chancen.

Internist (Berl), 58 (7)

DOI: 10.1007/s00108-017-0267-3 HZI-Repositorium PubMed

Krausze J., Probst C., Curth U., Reichelt J., Saha S., Schafflick D., Heinz D.W., ... , Mendel R.R., Kruse T. (2016)

Dimerization of the plant molybdenum insertase Cnx1E is required for synthesis of the molybdenum cofactor

Biochem.J., 474 (1)

DOI: 10.1042/BCJ20160846 HZI-Repositorium PubMed

Hebecker S., Krausze J., Hasenkampf T., Schneider J., Groenewold M., Reichelt J., Jahn D., ... , Heinz D.W., Moser J. (2015)

Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine

Proc.Natl.Acad.Sci.U.S.A., 112 (34)

DOI: 10.1073/pnas.1511167112 HZI-Repositorium PubMed

Kling A., Lukat P., Almeida D.V., Bauer A., Fontaine E., Sordello S., Zaburannyi N., Herrmann J., Wenzel S.C., Konig C., Ammerman N.C., Barrio M.B., Borchers K., Bordon-Pallier F., Brönstrup M., Courtemanche G., Gerlitz M., Geslin M., Hammann P., Heinz D.W., Hoffmann H., Klieber S., Kohlmann M., Kurz M., Lair C., Matter H., Nuermberger E., Tyagi S., Fraisse L., Grosset J.H., ... , Lagrange S., Müller R. (2015)

Targeting DnaN for tuberculosis therapy using novel griselimycins

Science, 348 (6239)

DOI: 10.1126/science.aaa4690 PubMed

Haufschildt K., Schmelz Stefan, Kriegler T.M., Neumann A., Streif J., Arai H., ... , Heinz Dirk W., Layer G. (2014)

The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues

Journal of Molecular Biology

Heinz Dirk W. (2013)

Secrets of a secretin

Structure, 21 (12)

Kolditz F., Krausze J., Heinz Dirk W., Niemann H.H., Muller-Goymann C.C. (2014)

Wound healing potential of a dimeric InlB variant analyzed by in vitro experiments on re-epithelialization of human skin models

European Journal of Pharmaceutics and Biopharmaceutics, 86 (2)

Fradrich C., Krausze Jörn, Quade N., Heinz Dirk, Jahn D., Hartig E. (2013)

Purification, crystallization and preliminary X-ray analysis of the effector domain of AlsR, an LysR-type transcriptional regulator from Bacillus subtilis

Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (Pt 5)

Kudryashev M., Stenta M., Schmelz S., Amstutz M., Wiesand U., Castano-Diez D., Degiacomi M.T., Munnich S., Bleck C.K., Kowal J., Diepold A., Heinz Dirk W., Dal Peraro M., ... , Cornelis G.R., Stahlberg H. (2013)

In situ structural analysis of the Yersinia enterocolitica injectisome

eLife, 2

DOI: 10.7554/eLife.00792 HZI-Repositorium PubMed

Hofmeyer T., Schmelz S., Degiacomi M.T., Dal Peraro M., Daneschdar M., Scrima Andrea, van den Heuvel Joop, ... , Heinz Dirk W., Kolmar H. (2013)

Arranged sevenfold: Structural insights into the C-terminal oligomerization domain of human C4b-binding protein

Journal of Molecular Biology, 425 (8)

DOI: 10.1016/j.jmb.2012.12.017 HZI-Repositorium PubMed

Moser J., Lange C., Krausze J., Rebelein J., Schubert W.D., Ribbe M.W., ... , Heinz Dirk W., Jahn D. (2013)

Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex

Proceedings of the National Academy of Sciences USA, 110 (6)

Quade N., Heinz Dirk W., Müller Rolf (2012)

Biosynthesis of secondary and natural materials: Where do unusual side chains in polyketides com from? [Woher stammen ungewöhnliche Seitenketten in Polyketiden?]

Biospektrum, 18 (7)

Glotzbach B., Schmelz S., Reinwarth M., Christmann A., Heinz Dirk W., Kolmar H. (2013)

Structural characterization of Spinacia oleracea trypsin inhibitor III (SOTI-III)

Acta Crystallographica Section D: Biological Crystallography, 69 (Pt 1)

DOI: 10.1107/S0907444912043880 HZI-Repositorium PubMed

Kugler J., Schmelz S., Gentzsch J., Haid S., Pollmann E., van den Heuvel Joop, Franke R., Pietschmann Thomas, ... , Heinz Dirk W., Collins J. (2012)

High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants

Journal of Biological Chemistry, 287 (46)

DOI: 10.1074/jbc.M112.393843 HZI-Repositorium PubMed

Quade N., Mendonca C., Herbst K., Heroven A.K., Ritter C., ... , Heinz D.W., Dersch P. (2012)

Structural Basis for Intrinsic Thermosensing by the Master Virulence Regulator RovA of Yersinia

Journal of Biological Chemistry, 287 (43)

DOI: 10.1074/jbc.M112.379156 HZI-Repositorium PubMed

Niemann H.H., Gherardi E., Bleymuller W.M., Heinz Dirk W. (2012)

Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complex

Protein Sciences, 21 (10)

Tischler M., Nasu D., Empting M., Schmelz S., Heinz Dirk W., Rottmann P., Kolmar H., Buntkowsky G., ... , Tietze D., Avrutina O. (2012)

Braces for the Peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations

Angewandte Chemie International Edition, 51 (15)

Wilke S., Gröbe Lothar*, Maffenbeier V., Jäger Volker*, Gossen M., Josewski J., Duda A., Polle L., Owens R.J., Wirth Dagmar*, Heinz Dirk* W., ... , van den Heuvel Joop*, Büssow Konrad* (2011)

Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development

PLoS ONE, 6 (12)

DOI: 10.1371/journal.pone.0027829 HZI-Repositorium PubMed

Quade N., Huo L., Rachid S., Heinz Dirk W.*, Müller Rolf* (2011)

Unusual carbon fixation gives rise to diverse polyketide extender units

Nature Chemical Biology, 8 (1)

de Groot J.C., Schluter K., Carius Y., Quedenau C., Vingadassalom D., Faix J., Weiss S.M., Reichelt J., Standfuss-Gabisch C., Lesser C.F., Leong J.M., Heinz Dirk W.*, ... , Büssow Konrad*, Stradal Theresia E.* (2011)

Structural Basis for Complex Formation between Human IRSp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. coli

Structure, 19 (9)

DOI: 10.1016/j.str.2011.06.015 HZI-Repositorium PubMed

Storbeck S., Saha S., Krausze J., Klink B.U., Heinz Dirk W.*, Layer G. (2011)

Crystal Structure of the Heme d1 Biosynthesis Enzyme NirE in Complex with Its Substrate Reveals New Insights into the Catalytic Mechanism of S-Adenosyl-L-methionine-dependent Uroporphyrinogen III Methyltransferases

Journal of Biological Chemistry, 286 (30)

DOI: 10.1074/jbc.M111.239855 HZI-Repositorium PubMed

Strube C.P., Homann A., Gamer M., Jahn D., Seibel J., Heinz Dirk W.* (2011)

Polysaccharide Synthesis of the Levansucrase SacB from Bacillus megaterium Is Controlled by Distinct Surface Motifs

Journal of Biological Chemistry, 286 (20)

DOI: 10.1074/jbc.M110.203166 HZI-Repositorium PubMed

Quade N., Dieckmann M., Haffke M., Heroven A.K., Dersch P., Heinz D.W. (2011)

Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis

Acta Crystallographica Section D: Biological Crystallography, 67 (Pt 2)

DOI: 10.1107/S0907444910049681 HZI-Repositorium PubMed

Haffke M., Menzel A., Carius Y., Jahn D., Heinz Dirk W.* (2010)

Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides

Acta Crystallographica Section D: Biological Crystallography, 66 (Pt 9)

Brocker M.J., Schomburg S., Heinz Dirk W.*, Jahn D., Schubert W.D., Moser J. (2010)

Crystal structure of the nitrogenase-like dark operative protochlorophyllide oxidoreductase catalytic complex (ChlN/ChlB)2

Journal of Biological Chemistry, 285 (35)

Heinz Dirk W.*, Betzel C., Wilmanns M. (2010)

Highlight: of systems and structures

Biological Chemistry, 391 (7)

Klink B.U., Barden S., Heidler T.V., Borchers C., Ladwein M., Stradal T.B., ... , Rottner K., Heinz D.W. (2010)

Structure of Shigella IpgB2 in complex with human RhoA: implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry

Journal of Biological Chemistry, 285 (22)

DOI: 10.1074/jbc.M110.107953 HZI-Repositorium PubMed

Layer G., Reichelt J., Jahn D., Heinz Dirk W.* (2010)

Structure and function of enzymes in heme biosynthesis

Protein Science, 19 (6)

Rand K., Noll C., Schiebel H.M., Kemken D., Dulcks T., Kalesse Markus*, ... , Heinz Dirk W.*, Layer G. (2010)

The oxygen-independent coproporphyrinogen III oxidase HemN utilizes harderoporphyrinogen as a reaction intermediate during conversion of coproporphyrinogen III to protoporphyrinogen IX

Biological Chemistry, 391 (1)

Heinemann I.U., Schulz C., Schubert W.D., Heinz Dirk W.*, Wang Y.G., Kobayashi Y., Awa Y., Wachi M., ... , Jahn D., Jahn M. (2010)

Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin

Antimicrobial Agents and Chemotherapy, 54 (1)

Ferraris D.M., Gherardi E., Di Y., Heinz Dirk W.*, Niemann H (2010)

Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InIB

Journal of Molecular Biology, 395 (3)

DOI: 10.1016/j.jmb.2009.10.074 HZI-Repositorium PubMed

Marin M., Heinz Dirk W.*, Pieper Dietmar H.*, Klink B.U. (2009)

Crystal structure and catalytic mechanism of 4-methylmuconolactone methylisomerase

Journal of Biological Chemistry, 284 (47)

Bublitz M., Nimtz Manfred*, Polle L., Holland C., Heinz Dirk W.*, Schubert Wolf-Dieter* (2009)

Structural basis for autoinhibition and activation of Auto, a virulence-associated peptidglycan hydrolase of L. monocytogenes

Molecular Microbiology, 71 (6)

Brocker M.J., Virus S., Ganskow S., Heathcote P., Heinz Dirk W.*, Schubert W.D., ... , Jahn D., Moser J. (2008)

ATP-driven reduction by dark-operative protochlorophyllide oxidoreductase from Chlorobium tepidum mechanistically resembles nitrogenase catalysis

Journal of Biological Chemistry, 283 (16)

Hagelüken G., Albrecht S.C., Steinmetz Heinrich*, Jansen Rolf*, Heinz Dirk W.*, ... , Kalesse Markus*, Schubert Wolf-Dieter* (2009)

The absolute configuration of rhizopodin and its inhibition of actin polymerization by dimerization

Angewandte Chemie International Edition, 48 (3)

DOI: 10.1002/anie.200802915 PubMed

Wiesand U., Sorg I., Amstutz M., Wagner S., van den Heuvel Joop*, Lührs Thorsten*, ... , Cornelis G.R., Heinz Dirk W.* (2009)

Structure of the type III secretion recognition protein YscU from Yersinia enterocolitica

Journal of Molecular Biology, 385 (3)

DOI: 10.1016/j.jmb.2008.10.034 HZI-Repositorium PubMed

Bublitz M., Holland C., Sabet C., Reichelt J., Cossart P., Heinz Dirk W.*, ... , Bierne H., Schubert Wolf-Dieter* (2008)

Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder

Journal of Molecular Biology, 378 (1)

Niemann H.H., Petoukhov M.V., Hartlein M., Moulin M., Gherardi E., Timmins P., ... , Heinz D.W., Svergun D.I. (2008)

X-ray and neutron small-angle scattering analysis of the complex formed by the met receptor and the Listeria monocytogenes invasion protein InlB

Journal of Molecular Biology, 377 (2)

DOI: 10.1016/j.jmb.2008.01.027 HZI-Repositorium PubMed

Wendt K.U., Weiss M.S., Cramer P., Heinz Dirk W.* (2008)

Structures and diseases

Nature Structural and Molecular Biology, 15 (2)

DOI: 10.1038/nsmb0208-117 HZI-Repositorium PubMed

Buettner C.R., Sorg I., Cornelis G.R., Heinz D.W., Niemann H.H. (2008)

Structure of the Yersinia enterocolitica

Journal of Molecular Biology, 375 (4)

DOI: 10.1016/j.jmb.2007.11.009 HZI-Repositorium PubMed

Hagelüken G., Wiehlmann L., Adams T.M., Kolmar H., Heinz Dirk W.*, ... , Tümmler B., Schubert Wolf-Dieter* (2007)

Crystal structure of the electron transfer complex rubredoxin-rubredoxin reductase of Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences of the United States of America (PNAS), 104 (30)

DOI: 10.1073/pnas.0702919104 HZI-Repositorium PubMed

Niemann H.N., Jäger Volker*, Butler P.J.G., van den Heuvel Joop*, Schmidt S., Ferraris D., ... , Gherardi E., Heinz Dirk W.* (2007)

Structure of the human receptor tyrosine kinase met in complex with the Listeria monocytogenes

Cell, 130 (2)

DOI: 10.1016/j.cell.2007.05.037 HZI-Repositorium PubMed

Wollert Thomas*, Heinz Dirk W.*, Schubert Wolf-Dieter* (2007)

Thermodynamically reengineering the listerial invasion complex InIA/E-Cadherin

Proceedings of the National Academy of Sciences of the United States of America (PNAS), 104 (35)

DOI: 10.1073/pnas.0702199104 HZI-Repositorium PubMed

Lüer C., Schauer S., Virus S., Schubert Wolf-Dieter*, Heinz Dirk W.*, ... , Jahn D., Moser J. (2007)

Glutamate recognition and hydride transfer by Escherichia coli

FEBS Journal, 274 (17)

DOI: 10.1111/j.1742-4658.2007.05989.x HZI-Repositorium PubMed

Wollert T., Pasche Bastian*, Rochon Maike*, Deppenmeier S., van den Heuvel Joop*, Gruber A.D., Heinz Dirk W.*, ... , Lengeling Andreas*, Schubert Wolf-Dieter* (2007)

Extending the host range of Listeria monocytogenes

Cell, 129 (5)

Frere F., Nentwich M., Gacond S., Heinz Dirk W.*, Neier R., Frankenberg-Dinkel N. (2006)

Probing the active site of Pseudomonas aeruginosa

Biochemistry, 45

Schulze J.O., Schubert Wolf-Dieter*, Moser J., Jahn D., Heinz Dirk W.* (2006)

Evolutionary relationship between initial enzymes of tetrapyrrole biosynthesis

Journal of Molecular Biology, 358

DOI: 10.1016/j.jmb.2006.02.064 HZI-Repositorium PubMed

Schulze J.O., Masoumi A., Nickel D., Jahn M., Schubert Wolf-Dieter*, Heinz Dirk W.* (2006)

Crystal structure of a non-discriminating glutamyl-tRNA synthetase

Journal of Molecular Biology, 361

DOI: 10.1016/j.jmb.2006.06.054 HZI-Repositorium PubMed

Niemann H.H., Schmoldt H.U., Wentzel A., Kolmar H., Heinz Dirk W.* (2006)

Barnase fusion as a tool to determine the crystal structure of the small disulfide-rich protein MceEeTI

Journal of Molecular Biology, 356

Layer G., Pierik A.J., Trost M., Jänsch Lothar*, Leech H.K., Warren M.J., Rigby S.E., Astner I., Grage K., Breckau D., ... , Heinz Dirk W.*, Jahn D. (2006)

The substrate radical of Escherichia coli

Journal of Biological Chemistry, 281

Jahn D., Moser J., Schubert Wolf-Dieter*, Heinz Dirk W.* (2006)

Transfer RNA-dependent aminolevulinic acid formation: structure and function of glutamyl-tRNA synthase, reductase and glutamate-1-semialdehyde-2,1-aminomutase

Heinz D.W., Weiss M.S., Wendt K.U. (2006)

Biomacromolecular interactions, assemblies and machines: A structural view

ChemBioChem, 7 (203)

DOI: 10.1002/cbic.200500459 HZI-Repositorium PubMed

Hagelüken G., Adams T.M., Wiehlmann L., Widow Ute*, Kolmar H., Tümmler B., ... , Heinz Dirk W.*, Schubert Wolf-Dieter* (2006)

The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences of the United States of America (PNAS), 103

DOI: 10.1073/pnas.0510501103 HZI-Repositorium PubMed

Frese S., Schubert Wolf-Dieter*, Findeis A.C., Marquardt T., Roske Y.S., ... , Stradal Theresia E.B.*, Heinz Dirk W.* (2006)

Phosphotyrosine binding specificities of Nck1 and Nck2

Journal of Biological Chemistry, 281

Lüer C., Schauer S., Möbius K., Schulze J., Schubert W.-D., Heinz D.W., ... , Jahn D., Moser J. (2005)

Complex formation between Glutamyl-tRNA Reductase and Glutamate-1-semialdehyde-2,1-aminomutase in Escherichia coli during the initial reactions of porphyrin biosynthesis

Journal of Biological Chemistry, 280

Layer G., Kervio E., Morlock G., Heinz D.W., Jahn D., ... , Retey J., Schubert W.-D. (2005)

Structural and functional comparison of HemN to other radical SAM enzymes

Biological Chemistry, 386

Heinz D.W., Schubert W.-D. (2005)

Proteins in motion

Angewandte Chemie - International Edition, 44

Heinz D.W., Schubert W.-D., Höfle G. (2005)

Much anticipated - The bioactive conformation of epothilone and its binding to tubulin

Angewandte Chemie - International Edition, 44

Buettner C., Cornelis G.R., Heinz D.W., Niemann H.H. (2005)

Crystal structure of Yersinia enterocolitica

Protein Science, 14

Astner I., Schulze J.O., van den Heuvel J., Jahn D., Schubert W.-D., Heinz D.W. (2005)

Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans

Embo Journal, 24

DOI: 10.1038/sj.emboj.7600792 HZI-Repositorium

Eiting M., Hagelüken G., Schubert W.-D., Heinz D.W. (2005)

The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes

Molecular Microbiology, 56 (2)

DOI: 10.1111/j.1365-2958.2005.04561.x PubMed

Reichelt J., Dieterich G., Kvesic M., Schomburg D., Heinz D.W. (2005)

BRAGI. Linking and visualization of database information in a 3D-viewer and modelling tool

Bioinformatics, 21

Heinz D.W., Schubert W.-D., Höfle G. (2005)

Lange gesucht - Die bioaktive Konformation von Epothilon und seine Bindung im Tubulin

Angewandte Chemie, 117 (9)

Frere F., Reents H., Schubert W.-D., Heinz D.W. (2005)

Tracking the evolution of porphobilinogen synthase metal dependence in vitro

Journal of Molecular Biology, 345 (5)

Dieterich G., Kvesic M., Schomburg D., Heinz D.W., Reichelt J. (2004)

Integrating public databases into an existing protein visualization and modeling program BRAGI

Lecture Notes in Informatics, P-53

Layer G., Heinz D.W., Jahn D., Schubert W.-D. (2004)

Structure and function of radical SAM enzymes

Current Opinion in Chemical Biology, 8

Ehinger S., Schubert W.-D., Bergmann S., Hammerschmidt S., Heinz D.W. (2004)

Plasmin(ogen)-binding alpha-Enolase from Streptococcus pneumoniae

Journal of Molecular Biology, 343

DOI: 10.1016/j.jmb.2004.08.088 PubMed

Niemann H., Schubert W.-D., Heinz D. (2004)

Adhesins and invasions of pathogenic bacteria: a structural view

Microbes and Infection, 6

Freiberg A., Machner M-P., Pfeil W., Schubert W.-D., Heinz D.W., Seckler R. (2004)

Folding and stability of the leucine-rich repeat domain of internalin B from Listeria monocytogenes

Journal of Molecular Biology, 337 (2)

Machner M.P., Frese S., Schubert W.-D., Orian-Rousseau V., Gherardi E., Wehland J., ... , Niemann H.H., Heinz D.W. (2003)

Aromatic amino acids at the surface of In1B are essential for host cell invasion by Lysteria monocytogenes

Molecular Microbiology, 48

Moser J., Frere F., Heinz D.W., Jahn D., Schubert W.-D. (2003)

Die tRNA-abhängige Tetrapyrrol-Biosynthese

Biospektrum, 9

Schubert W.-D., Heinz D.W. (2003)

Details der Wechselwirkung zwischen Bakterium und Mensch

Laborwelt (1)

Heesemann J., Heinz D.W., Rüssmann H., Wehland J., Goebel W., Kuhn M. (2003)

Lektionen aus der Bakterienwelt: Ausnutzung von Wirtszellprozessen durch pathogene Mikroben

Biospektrum, 9

Schubert W.-D., Heinz D.W. (2003)

Structural aspects of adhesion and invasion of host cells by the human pathogen Listeria monocytogenes

ChemBioChem, 4

Layer G., Moser J., Heinz D.W., Jahn D., Schubert W.-D. (2003)

Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of radical SAM enzymes

Embo Journal, 22

DOI: 10.1093/emboj/cdg598 HZI-Repositorium PubMed

van den Heuvel J., Heinz D.W. (2002)

"Plug and Play"-expression systems for high-quality production of recombinant proteins for structural analysis

Gene Function & Disease, 3 (1/2)

Schubert W.D., Moser J., Schauer S., Heinz D.W., Jahn D. (2002)

Structure and function of glutamyl-tRNA reductases, the first enzyme of tetrapyrrole biosynthesis in plants and prokaryotes

Photosynthesis Research, 74

Schubert W.-D., Urbanke C., Ziehm T., Beier V., Machner M.P., Domann E., Wehland J., ... , Chakraborty T., Heinz D.W. (2002)

Structure of the complex of internalin, a major invasion protein of Listeria monocytogenes with its human receptor, E-cadherin.

Cell, 111

Schauer S., Chaturvedi S., Randau L., Moser J., Kitabatake M., Lorenz S., Verkamp E., Schubert W.-D., Nakayashiki T., Murai M., Wall K., Thomann U., Heinz D.W., Inokuchi H., ... , Söll D., Jahn D. (2002)

Escherichia coli glutamyl-tRNA reductase: trapping the thioester intermediate.

Journal of Biological Chemistry, 247 (50)

Moser J., Schubert W.-D., Heinz D.W., Jahn D. (2002)

Structure and function of glutamyl-tRNA-reductase involved in 5-aminolevulinic acid formation

Biochemical Society Transactions, 30

Heinz D.W., Jahn D. (2002)

Strukturbiologie zur gerichteten Wirkstoffentwicklung

CHEManager, 11

Heinz D.W. (2002)

Modellsystem für Infektionen - Pathogene Bakterien auf ihrem unheilvollen Weg verfolgt

Jahreshefte der Helmholtz-Gesellschaft

Schubert W.D., Göbel G., Kloer D., Chakraborty T., Wehland J., ... , Domann E., Heinz D.W. (2001)

Crystal structure of the conserved core of internalins from the human pathogen Listeria monocytogenes.

Nova Acta Leopoldina Supplementum, 16

Schubert W.D., Göbel G., Diepholz M., Darji A., Kloer D., Hain T., Chakraborty T., Wehland J., ... , Domann E., Heinz D.W. (2001)

Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain

Journal of Molecular Biology, 312 (4)

Moser J., Schubert W.D., Beier V., Bringemeier I., Jahn D., Heinz D.W. (2001)

V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA- dependent tetrapyrrole biosynthesis

Embo Journal, 20 (23)

Machner M.P., Urbanke C., Barzik M., Otten S., Sechi A.S., ... , Wehland J., Heinz D.W. (2001)

ActA from Listeria monocytogenes can interact with up to four Ena/VASP homology 1 domains simultaneously

Journal of Biological Chemistry, 276 (43)

Barzik M., Carl U.D., Schubert W.D., Frank R., Wehland J., Heinz D.W. (2001)

The N-terminal domain of Homer/Vesl is a new class II EVH1 domain

Journal of Molecular Biology, 309 (1)

Barzik M., Schubert W.D., Carl U., Wehland J., Heinz D.W. (2000)

Crystallization and preliminary X-ray analysis of the EVH1 domain of Vesl-2b

Acta crystallographica.Section D: Biological crystallography., 56 (7)

DOI: 10.1107/S0907444900005758 HZI-Repositorium

Prof Dr Dr h.c. Dirk Heinz

Research group

Location