Prof Dr Martin Korte
Martin Korte has already focused on synaptic plasticity during his PhD projects "Signaling Systems at hippocampal synapses" at the Max Planck Institute (MPI) for Neurobiology in Martinsried. Afterwards he became a research group leader at the MPI of Neurobiology.
2004 Martin Korte got the professorship at the Technische Universität Braunschweig. Since 2007 he is the professor of cellular neurobiology and the director of the zoological institute at the TU Braunschweig.
In 2012 he established the research group neuroinflammation and neurodegeneration at the Helmholtz Centre for Infection Research and thereby connect with his experience in the fields of cellular neurobiology and neurophysiology the areas of infection and neurodegenerative diseases.
Publications
H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro
Frontiers in Cellular Neuroscience,
18
The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain
Journal of Neuroinflammation,
21
(1)
The effects of urolithin A on poly I:C-induced microglial activation
Frontiers in Cellular Neuroscience,
18
Prolonged and specific spatial training during adolescence reverses adult hippocampal network impairments in a mouse model of fragile X syndrome
Neurobiol.Dis.,
185
Deletion of p75(NTR) rescues the synaptic but not the inflammatory status in the brain of a mouse model for Alzheimer's disease
Front Mol.Neurosci.,
16
Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection
Frontiers in Pharmacology,
14
Phosphorylation of the actin-binding protein profilin2a at S137 modulates bidirectional structural plasticity at dendritic spines
Front.Cell Dev.Biol.,
11
How viral infections cause neuronal dysfunction: a focus on the role of microglia and astrocytes
Biochem.Soc.Trans.
SiMeEx, a simplified method for metabolite extraction of adherent mammalian cells
Front.Mol.Biosci.,
9
Antibody Properties Associate with Clinical Phenotype in LGI1 Encephalitis
Cells,
12
(2)
Lack of APLP1 leads to subtle alterations in neuronal morphology but does not affect learning and memory
Front.Mol.Neurosci.,
15
Repeated performance of spatial memory tasks ameliorates cognitive decline in APP/PS1 mice
Behav.Brain Res.,
438
(February 2023)
Opening the box of PANTHORA in Alzheimer's disease
Signal Transduct.Target.Ther.,
7
(1)
Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal Neurons
Front.Mol.Neurosci.,
15
IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model
eLife,
11
Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2
Biochim.Biophys.Acta Mol.Basis.Dis.,
1868
(12)
APPsa[alpha] rescues Tau-induced synaptic pathology
J.Neurosci.
Influenza A Virus (H1N1) Infection Induces Microglial Activation and Temporal Dysbalance in Glutamatergic Synaptic Transmission
MBio.,
12
(5)
Nogo-a modulates the synaptic excitation of hippocampal neurons in a ca2+-dependent manner
Cells,
10
(9)
Neuroligin-1 mediates presynaptic maturation through brain-derived neurotrophic factor signaling
BMC Biol.,
19
(1)
Cortactin Contributes to Activity-Dependent Modulation of Spine Actin Dynamics and Spatial Memory Formation
Cells,
10
(7)
Long-Term Consequence of Non-neurotropic H3N2 Influenza A Virus Infection for the Progression of Alzheimer's Disease Symptoms
Front Cell Neurosci.,
15
Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype
EMBO J.,
40
(12)
Respiratory viral infections and associated neurological manifestations
Neuroforum,
27
(2)
The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease
Proc Natl Acad Sci U S A,
117
(50)
The impact of the digital revolution on human brain and behavior: where do we stand?
Dialogues Clin Neurosci,
22
(2)
Signaling via the p75 neurotrophin receptor facilitates amyloid-b[beta]-induced dendritic spine pathology
Sci.Rep.,
10
(1)
BDNF signaling during the lifetime of dendritic spines
Cell Tissue Res.,
382
(1)
Enduring changes in neuronal function upon systemic inflammation are NLRP3 inflammasome dependent
J.Neurosci.,
40
(28)
Type I Interferon Receptor Signaling in Astrocytes Regulates Hippocampal Synaptic Plasticity and Cognitive Function of the Healthy CNS
Cell Rep.,
31
(7)
Fingolimod modulates dendritic architecture in a BDNF-dependent manner
Int.J.Mol.Sci.,
21
(9)
Lack of APP and APLP2 in GABAergic Forebrain Neurons Impairs Synaptic Plasticity and Cognition
Cereb.Cortex,
30
(7)
Cell type-specific effects of BDNF in modulating dendritic architecture of hippocampal neurons
Brain Struct.Funct.,
223
(8)
Amyloid, APP, and Electrical Activity of the Brain
Neuroscientist.,
26
(3)
Fast Regulation of GABAAR Diffusion Dynamics by Nogo-A Signaling
Cell Rep.,
29
(3)
FMRP Modulates Activity-Dependent Spine Plasticity by Binding Cofilin1 mRNA and Regulating Localization and Local Translation
Cereb.Cortex,
29
(12)
Modeling neurodegenerative Spinocerebellar Ataxia type 13 in zebrafish using a Purkinje neuron specific tunable co-expression system
J.Neurosci.,
39
(29)
Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice
Neural Plast.,
2019
Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus
Cereb.Cortex,
28
(12)
The diphenylpyrazole compound anle138b blocks Ab[beta] channels and rescues disease phenotypes in a mouse model for amyloid pathology
EMBO Mol.Med.,
10
(1)
Distinct in vivo roles of secreted APP ectodomain variants APPsa[alpha] and APPsb[beta] in regulation of spine density, synaptic plasticity, and cognition
EMBO J.,
37
(1)
Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function
J.Neurosci.,
38
(12)
Imbalance of synaptic actin dynamics as a key to the Fragile X syndrome?
J.Physiol,
596
(14)
Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer's disease
Proc.Natl.Acad.Sci.U.S.A,
114
(21)
APLP1 is a synaptic cell adhesion molecule, supporting maintenance of dendritic spines and basal synaptic transmission
J.Neurosci.,
37
(21)
Not just amyloid: physiological functions of the amyloid precursor protein family
Nat.Rev.Neurosci.,
18
(5)
Novel insights into the physiological function of the APP (GENE) family and its proteolytic fragments in synaptic plasticity
Front.Mol.Neurosci.,
9
Satb2 determines miRNA expression and long-term memory in the adult central nervous system
eLife,
5
(November2016)
Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice
Brain,
140
(3)
Altered Connectivity and Synapse Maturation of the Hippocampal Mossy Fiber Pathway in a Mouse Model of the Fragile X Syndrome
Cereb.Cortex,
28
(3)
Nogo-A regulates spatial learning as well as memory formation and modulates structural plasticity in the adult mouse hippocampus
Neurobiol.Learn.Mem.,
138
(Feb)
Nogo-66 Restricts Synaptic Strengthening via Lingo1 and the ROCK2-Cofilin Pathway to Control Actin Dynamics
Cereb.Cortex,
27
(5)
Neuronal profilins in health and disease: Relevance for spine plasticity and Fragile X syndrome
Proc.Natl.Acad.Sci U.S A,
113
(12)
Cellular and System Biology of Memory: Timing, Molecules, and Beyond
Physiol Rev.,
96
(2)
Erratum to: Acute function of secreted amyloid precursor protein fragment APPs? in synaptic plasticity(Acta Neuropathol, Doi:10.1007/s00401-014-1368-x)
Acta Neuropathol.,
129
(1)
Nogo-A controls structural plasticity at dendritic spines by rapidly modulating actin dynamics
Hippocampus,
26
(6)
Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with alzheimer-like Tau pathology
Hum.Mol.Genet.,
24
(21)
The APP intracellular domain is required for normalsynaptic morphology, synaptic plasticity, and hippocampus-dependent behavior
J.Neurosci.,
35
(49)
Viral gene transfer of APPsa[alpha] rescues synaptic failure in an Alzheimer's disease mouse model
Acta Neuropathol.,
131
Two-photon correlation spectroscopy in single dendritic spines reveals fast actin filament reorganization during activity-dependent growth
PLoS ONE,
10
(5)
Cannabinoid CB1 receptor calibrates excitatory synaptic balance in the mouse hippocampus
J.Neurosci.,
35
(9)
Acute function of secreted amyloid precursor protein fragment APPs? in synaptic plasticity
Acta Neuropathol.,
129
(1)
Chronic murine toxoplasmosis is defined by subtle changes in neuronal connectivity
DMM Disease Models and Mechanisms,
7
(4)
Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons
PLoS Pathogens,
10
(3)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Nature,
493
(7434)
