Prof Dr Susanne Engelmann

Prof Dr Susanne Engelmann
Research Group Leader
+49 531 6181-3041

Susanne Engelmann studied biology at the University of Greifswald, earning her Ph.D. at the Institute for Microbiology. In 2001, she became head of the Pathogenomics research unit at the University of Greifswald Institute for Microbiology and, in 2013, was appointed Professor of Microbial Proteome Research at Braunschweig University of Technology. Concurrently, she also holds an appointment as head of the HZI’s Microbial Proteomics Research Group.

Publications
Müller-Langhans K., Oberberger L., Zablotski Y., Engelmann S., Hoedemaker M., Kühn C., Schuberth H.J., Zerbe H., ... , Petzl W., Meyerholz-Wohllebe M.M. (2024)
Cows with diverging haplotypes show differences in differential milk cell count, milk parameters and vaginal temperature after S. aureus challenge but not after E. coli challenge
BMC Veterinary Research, 20 (1)
DOI: 10.1186/s12917-024-03996-y HZI-Repositorium PubMed
Fuchs S., Engelmann S. (2023)
Small proteins in bacteria - Big challenges in prediction and identification
Proteomics.
DOI: 10.1002/pmic.202200421 HZI-Repositorium PubMed
Seffer M.T., Weinert M., Molinari G., Rohde M., Gröbe L., ... , Kielstein J.T., Engelmann S. (2023)
Staphylococcus aureus binding to Seraph- â
PLoS ONE, 18 (3)
DOI: 10.1371/journal.pone.0283304 HZI-Repositorium PubMed
Becker D., Weikard R., Heimes A., Hadlich F., Hammon H.M., Meyerholz M.M., Petzl W., Zerbe H., Schuberth H.J., Hoedemaker M., Schmicke M., ... , Engelmann S., Kühn C. (2022)
Allele-biased expression of the bovine APOB gene associated with the cholesterol deficiency defect suggests cis-regulatory enhancer effects of the LTR retrotransposon insertion
Sci.Rep., 12 (1)
DOI: 10.1038/s41598-022-17798-5 HZI-Repositorium PubMed
Thunberg U., Hugosson S., Fredlund H., Cai Y., Ehricht R., Monnecke S., Müller E., ... , Engelmann S., Söderquist B. (2019)
Anti-Staphyloccocal humoral immune response in patients with chronic rhinosinusitis
Rhinology online, 2019 (2)
DOI: 10.4193/RHINOL/19.002 HZI-Repositorium
Mayer K., Kucklick M., Marbach H., Ehling-Schulz M., Engelmann S., Grunert T. (2021)
Within-host adaptation of staphylococcus aureus in a bovine mastitis infection is associated with increased cytotoxicity
Int.J.Mol.Sci., 22 (16)
DOI: 10.3390/ijms22168840 HZI-Repositorium PubMed
Bartholomäus A., Kolte B., Mustafayeva A., Goebel I., Fuchs S., Benndorf D., ... , Engelmann S., Ignatova Z. (2021)
smORFer: a modular algorithm to detect small ORFs in prokaryotes
Nucleic Acids Res.
DOI: 10.1093/nar/gkab477 HZI-Repositorium PubMed
Fuchs S., Kucklick M., Lehmann E., Beckmann A., Wilkens M., Kolte B., Mustafayeva A., Ludwig T., Diwo M., Wissing J., Jänsch L., Ahrens C.H., ... , Ignatova Z., Engelmann S. (2021)
Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach
PLoS.Genet., 17 (6)
DOI: 10.1371/journal.pgen.1009585 HZI-Repositorium PubMed
Beier N., Kucklick M., Fuchs S., Mustafayeva A., Behringer M., Hürtig E., ... , Jahn D., Engelmann S. (2021)
Adaptation of Dinoroseobacter shibae to oxidative stress and the specific role of RirA
PLoS ONE, 16 (3)
DOI: 10.1371/journal.pone.0248865 HZI-Repositorium PubMed
Wang H., Beier N., Boedeker C., Sztajer H., Henke P., Neumann-Schaal M., Mansky J., Rohde M., Overmann J., Petersen J., Klawonn F., Kucklick M., Engelmann S., ... , Tomasch J., Wagner-Döbler I. (2021)
Dinoroseobacter shibae outer membrane vesicles are enriched for the chromosome dimer resolution site dif
mSystems., 6 (1)
DOI: 10.1128/mSystems.00693-20 HZI-Repositorium PubMed
Seffer M.T., Eden G., Engelmann S., Kielstein J.T. (2020)
Elimination of Staphylococcus aureus from the bloodstream using a novel biomimetic sorbent haemoperfusion device
BMJ Case.Rep., 13 (8)
DOI: 10.1136/bcr-2020-235262 HZI-Repositorium PubMed
Heimes A., Brodhagen J., Weikard R., Seyfert H.M., Becker D., Meyerholz M.M., Petzl W., Zerbe H., Hoedemaker M., Rohmeier L., Schuberth H.J., Schmicke M., ... , Engelmann S., Kühn C. (2020)
Hepatic Transcriptome Analysis Identifies Divergent Pathogen-Specific Targeting-Strategies to Modulate the Innate Immune System in Response to Intramammary Infection
Front.Immunol., 11
DOI: 10.3389/fimmu.2020.00715 HZI-Repositorium PubMed
Heimes A., Brodhagen J., Weikard R., Becker D., Meyerholz M.M., Petzl W., Zerbe H., Schuberth H.J., Hoedemaker M., Schmicke M., ... , Engelmann S., Kühn C. (2020)
Cows selected for divergent mastitis susceptibility display a differential liver transcriptome profile after experimental Staphylococcus aureus mammary gland inoculation
J.Dairy Sci., 103 (7)
DOI: 10.3168/jds.2019-17612 HZI-Repositorium PubMed
Rohmeier L., Petzl W., Koy M., Eickhoff T., Hülsebusch A., Jander S., Macias L., Heimes A., Engelmann S., Hoedemaker M., Seyfert H.M., Kühn C., Schuberth H.J., ... , Zerbe H., Meyerholz M.M. (2020)
In vivo model to study the impact of genetic variation on clinical outcome of mastitis in uniparous dairy cows
BMC.Vet.Res., 16 (1)
DOI: 10.1186/s12917-020-2251-8 HZI-Repositorium PubMed
Kohler C., Proctor R.A., Bayer A.S., Yeaman M.R., Lalk M., ... , Engelmann S., Mishra N.N. (2019)
Proteomic and Membrane Lipid Correlates of Reduced Host Defense Peptide
Antibiotics.(Basel), 8 (4)
DOI: 10.3390/antibiotics8040169 HZI-Repositorium PubMed
Meyerholz M.M., Rohmeier L., Eickhoff T., Hülsebusch A., Jander S., Linden M., Macias L., Koy M., Heimes A., Gorríz-Martín L., Segelke D., Engelmann S., Schmicke M., Hoedemaker M., Petzl W., Zerbe H., ... , Schuberth H.J., Kühn C. (2019)
Genetic selection for bovine chromosome 18 haplotypes associated with divergent somatic cell score affects postpartum reproductive and metabolic performance
J.Dairy Sci., 102 (11)
DOI: 10.3168/jds.2018-16171 HZI-Repositorium PubMed
Heimes A., Brodhagen J., Weikard R., Hammon H.M., Meyerholz M.M., Petzl W., Zerbe H., Engelmann S., Schmicke M., Hoedemaker M., ... , Schuberth H.J., Kühn C. (2019)
Correction to: Characterization of functional traits with focus on udder health in heifers with divergent paternally inherited haplotypes on BTA18 (BMC Vet Res (2019) 15:241 DOI: 10.1186/s12917-019-1988-4)
BMC Vet.Res., 15 (1)
DOI: 10.1186/s12917-019-2034-2 HZI-Repositorium PubMed
Heimes A., Brodhagen J., Weikard R., Hammon H.M., Meyerholz M.M., Petzl W., Zerbe H., Engelmann S., Schmicke M., Hoedemaker M., ... , Schuberth H.J., Kühn C. (2019)
Characterization of functional traits with focus on udder health in heifers with divergent paternally inherited haplotypes on BTA18
BMC Vet.Res., 15 (1)
DOI: 10.1186/s12917-019-1988-4 HZI-Repositorium PubMed
Brodhagen J., Weikard R., Thom U., Heimes A., Günther J., Hadlich F., Zerbe H., Petzl W., Meyerholz M.M., Hoedemaker M., Schuberth H.J., ... , Engelmann S., Kühn C. (2019)
Development and evaluation of a milk protein transcript depletion method for differential transcriptome analysis in mammary gland tissue
BMC GENOMICS, 20 (1)
DOI: 10.1186/s12864-019-5781-3 HZI-Repositorium PubMed
Seiß E.A., Krone A., Formaglio P., Goldmann O., Engelmann S., Schraven B., ... , Medina E., Müller A.J. (2019)
Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils
Sci.Rep., 9 (1)
DOI: 10.1038/s41598-019-42129-6 HZI-Repositorium PubMed
Lerch M.F., Schoenfelder S.M.K., Marincola G., Wencker F.D.R., Eckart M., Förstner K.U., Sharma C.M., Thormann K.M., Kucklick M., ... , Engelmann S., Ziebuhr W. (2019)
A non-coding RNA from the intercellular adhesin (ica) locus of Staphylococcus epidermidis controls polysaccharide intercellular adhesin (PIA)-mediated biofilm formation
Mol.Microbiol., 111 (6)
DOI: 10.1111/mmi.14238 PubMed
Engelmann S., Fuchs S. (2018)
Proteomic Signatures in Staphylococcus aureus
Methods Mol.Biol., 1841 (chapter 9)
DOI: 10.1007/978-1-4939-8695-8_9
Graf A., Lewis R.J., Fuchs S., Pagels M., Engelmann S., ... , Riedel K., Pané-Farré J. (2018)
The hidden lipoproteome of Staphylococcus aureus
Int.J.Med.Microbiol., 308 (6)
DOI: 10.1016/j.ijmm.2018.01.008 PubMed
Romero Pastrana F., Neef J., Koedijk D.G.A.M., De Graaf D., Duipmans J., Jonkman M.F., Engelmann S., ... , van Dijl J.M., Buist G. (2018)
Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins
Sci.Rep., 8 (1)
DOI: 10.1038/s41598-018-21724-z HZI-Repositorium PubMed
Treffon J., Block D., Moche M., Reiss S., Fuchs S., Engelmann S., Becher D., Langhanki L., Mellmann A., ... , Peters G., Kahl B.C. (2018)
Adaptation of Staphylococcus aureus to the airways of cystic fibrosis patients by the up-regulation of superoxide dismutase M and iron-scavenging proteins
J.Infect.Dis., 217 (9)
DOI: 10.1093/infdis/jiy012 PubMed
Boedeker C., Schuler M., Reintjes G., Jeske O., van Teeseling M.C., Jogler M., Rast P., Borchert D., Devos D.P., Kucklick M., Schaffer M., Kolter R., van Niftrik L., Engelmann S., Amann R., Rohde M., ... , Engelhardt H., Jogler C. (2017)
Determining the bacterial cell biology of Planctomycetes
Nat.Commun., 8
DOI: 10.1038/ncomms14853 HZI-Repositorium PubMed
Engelmann S., Fuchs S., Hecker M. (2016)
Physiological proteomics of S. aureus - from the protein inventory to stress physiology and in vivo adaption
(7)
DOI: 10.21775/9781910190494.07 HZI-Repositorium PubMed
Vu C.H., Kolata J., Stentzel S., Beyer A., Gesell Salazar M., Steil L., Pane-Farre J., Rühmling V., Engelmann S., Götz F., van Dijl J.M., Hecker M., Mäder U., Schmidt F., ... , Völker U., Bröker B.M. (2016)
Adaptive immune response to lipoproteins of Staphylococcus aureus in healthy subjects
Proteomics, 16 (20)
DOI: 10.1002/pmic.201600151 PubMed
Zühlke D., Dörries K., Bernhardt J., Maaß S., Muntel J., Liebscher V., Pané-Farré J., Riedel K., Lalk M., Völker U., Engelmann S., Becher D., ... , Fuchs S., Hecker M. (2016)
Costs of life-Dynamics of the protein inventory of Staphylococcus aureus during anaerobiosis
Sci.Rep., 6
DOI: 10.1038/srep28172 HZI-Repositorium PubMed
Stentzel S., Teufelberger A., Nordengrun M., Kolata J., Schmidt F., van Crombruggen K., Michalik S., Kumpfmuller J., Tischer S., Schweder T., Hecker M., Engelmann S., Volker U., Krysko O., ... , Bachert C., Broker B.M. (2016)
Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus
J Allergy Clin.Immunol., 139 (2)
DOI: 10.1016/j.jaci.2016.03.045 HZI-Repositorium PubMed
Selle M., Hertlein T., Oesterreich B., Klemm T., Kloppot P., Muller E., Ehricht R., Stentzel S., Broker B.M., ... , Engelmann S., Ohlsen K. (2016)
Global antibody response to Staphylococcus aureus live-cell vaccination
Sci Rep., 6
DOI: 10.1038/srep24754 HZI-Repositorium PubMed
Kloppot P., Selle M., Kohler C., Stentzel S., Fuchs S., Liebscher V., Müller E., Kale D., Ohlsen K., Bröker B.M., Zipfel P.F., Kahl B.C., Ehricht R., ... , Hecker M., Engelmann S. (2015)
Microarray-based identification of human antibodies against Staphylococcus aureus antigens
Proteomics Clin.Appl., 9 (11-12)
DOI: 10.1002/prca.201400123 PubMed
Bauer I., Gunther J., Wheeler T.T., Engelmann S., Seyfert H.M. (2015)
Extracellular milieu grossly alters pathogen-specific immune response of mammary epithelial cells
BMC Vet.Res, 11
DOI: 10.1186/s12917-015-0489-3 HZI-Repositorium PubMed
Stentzel S., Sundaramoorthy N., Michalik S., Nordengrun M., Schulz S., Kolata J., Kloppot P., Engelmann S., Steil L., Hecker M., Schmidt F., Volker U., ... , Roghmann M.C., Broker B.M. (2015)
Specific serum IgG at diagnosis of Staphylococcus aureus bloodstream invasion is correlated with disease progression
J Proteomics, 128
DOI: 10.1016/j.jprot.2015.06.018 HZI-Repositorium PubMed
Hasenberg A., Hasenberg M., Mann L., Neumann F., Borkenstein L., Stecher M., Kraus A., Engel D.R., Klingberg A., Seddigh P., Abdullah Z., Klebow S., Engelmann S., Reinhold A., Brandau S., Seeling M., Waisman A., Schraven B., Gothert J.R., ... , Nimmerjahn F., Gunzer M. (2015)
Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes
Nat.Methods, 12 (5)
Neumann Y., Ohlsen K., Donat S., Engelmann Susanne, Kusch H., Albrecht D., Cartron M., ... , Hurd A., Foster S.J. (2014)
The effect of skin fatty acids on Staphylococcus aureus
Archives of Microbiology, 197
Halbedel S., Reiss S., Hahn B., Albrecht D., Mannala G.K., Chakraborty T., Hain T., ... , Engelmann Susanne, Flieger A. (2014)
A systematic proteomic analysis of listeria monocytogenes house-keeping protein secretion systems
Molecular and Cellular Proteomics, 13 (11)
DOI: 10.1074/mcp.M114.041327 HZI-Repositorium PubMed
Müller M., Reiß S., Schlüter R., Mäder U., Beyer A., Reiß W., Marles-Wright J., Lewis R.J., Pförtner H., Völker U., Riedel K., Hecker M., ... , Engelmann Susanne, Pané-Farré J. (2014)
Deletion of membrane-associated Asp23 leads to upregulation of cell wall stress genes in Staphylococcus aureus
Molecular Microbiology, 93 (6)
DOI: 10.1111/mmi.12733 PubMed
Kusch H., Engelmann Susanne (2013)
Secrets of the secretome in Staphylococcus aureus
International Journal of Medical Microbiology, 304
Engelmann S., Togni M., Thielitz A., Reichardt P., Kliche S., Reinhold D., ... , Schraven Burkhart, Reinhold A. (2013)
T cell-independent modulation of experimental autoimmune encephalomyelitis in ADAP-deficient mice
Journal of Immunology, 191 (10)
Togni M., Engelmann S., Reinhold D., Schraven B., Reinhold A. (2012)
The adapter protein ADAP is required for selected dendritic cell functions
Cell Communication and Signalling, 10 (1)
DOI: 10.1186/1478-811X-10-14 HZI-Repositorium PubMed
Kusch K., Hanke K., Holtfreter S., Schmudde M., Kohler C., Erck C., Wehland J., Hecker M., Ohlsen K., ... , Broker B., Engelmann S. (2011)
The influence of SaeRS and sigma(B) on the expression of superantigens in different Staphylococcus aureus isolates
International Journal of Medical Microbiology, 301 (6)
DOI: 10.1016/j.ijmm.2011.01.003 PubMed
Quiel A., Jurgen B., Piechotta G., Le Foll A.P., Ziebandt A.K., Kohler C., Koster D., Engelmann S., Erck C., Hintsche R., Wehland Jürgen*, ... , Hecker M., Schweder T. (2009)
Electrical protein array chips for the detection of staphylococcal virulence factors
Applied Microbiology and Biotechnology, 85 (5)

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