Prof Dr Till Strowig

Prof Dr Till Strowig
Head of Research Group
+49 531 6181-4700

Till Strowig studied Medical Biotechnology at the “Technische Universität” Berlin. After his diploma thesis at The Rockefeller University in New York, he remained there for his Ph.D. thesis supported by a fellowship from the Boehringer Ingelheim Foundation. He continued his scientific training in the laboratory of Richard Flavell at Yale University supported by a postdoctoral fellowship from the Leukemia and Lymphoma Society. Since June 2013, Till Strowig is heading the Young Investigator Group “Microbial Immune Regulation“ at the HZI, which has grown into the department of the same name since February 2019.

Publications
el Mouali Y., Tawk C., Huang K.D., Amend L., Lesker T.R., Ponath F., ... , Vogel J., Strowig T. (2024)
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization
Cell Host.Microbe
DOI: 10.1016/j.chom.2024.09.008 HZI-Repositorium PubMed
Roesner L.M., Gupta M.K., Kopfnagel V., van Unen N., Kemmling Y., Heise J., Castell S., Jiang X., Riemann L., Traidl S., Lange B., Sühs K., Illig T., Strowig T., Li Y., Förster R., Huehn J., Schulz T.F., ... , Werfel T., RESIST SI Cohort Investigators (2024)
Correction to: The RESIST Senior Individuals Cohort: Design, participant characteristics and aims (GeroScience, (2024), 10.1007/s11357-024-01299-6)
GeroScience
DOI: 10.1007/s11357-024-01380-0 HZI-Repositorium PubMed
Essex M., Pascual-Leone B.M., Löber U., Kuhring M., Zhang B., Brüning U., Fritsche-Guenther R., Krzanowski M., Fiocca Vernengo F., Brumhard S., Röwekamp I., Bielecka A., Lesker T.R., Wyler E., Landthaler M., Mantei A., Meisel C., Caesar S., Thibeault C., Corman V.M., Marko L., Suttorp N., Strowig T., Kurth F., Sander L.E., Li Y., Kirwan J.A., ... , Forslund S.K., Opitz B. (2024)
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19
npj Biofilms and Microbiomes, 10 (1)
DOI: 10.1038/s41522-024-00538-0 HZI-Repositorium PubMed
Roesner L.M., Gupta M.K., Kopfnagel V., van Unen N., Kemmling Y., Heise J.K., Castell S., Jiang X., Riemann L., Traidl S., Lange B., Sühs K.W., Illig T., Strowig T., Li Y., Förster R., Huehn J., Schulz T.F., ... , Werfel T., RESIST SI Cohort Investigators (2024)
The RESIST Senior Individuals Cohort: Design, participant characteristics and aims
GeroScience
DOI: 10.1007/s11357-024-01299-6 HZI-Repositorium PubMed
Osbelt L., Almasi E.D.H., Wende M., Kienesberger S., Voltz A., Lesker T.R., Muthukumarasamy U., Knischewski N., Nordmann E., Bielecka A.A., Giralt-Zuniga M., Kaganovitch E., Kühne C., Baier C., Pietsch M., Müsken M., Greweling-Pils M.C., Breinbauer R., Flieger A., Schlüter D., Müller R., Erhardt M., ... , Zechner E.L., Strowig T. (2024)
Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms
Nat.Microbiol.
DOI: 10.1038/s41564-024-01710-0 HZI-Repositorium PubMed
Büssing R., Bublitz A., Karge B., Brönstrup M., Strowig T., Ott I. (2024)
An organometallic hybrid antibiotic of metronidazole with a Gold(I) N-Heterocyclic Carbene overcomes metronidazole resistance in Clostridioides difficile
J.Biol.Inorg.Chem.
DOI: 10.1007/s00775-024-02064-y HZI-Repositorium PubMed
Neumann C., Blume J., Roy U., Teh P.P., Vasanthakumar A., Beller A., Liao Y., Heinrich F., Arenzana T.L., Hackney J.A., Eidenschenk C., G+ílvez E.J.C., Stehle C., Heinz G.A., Maschmeyer P., Sidwell T., Hu Y., Amsen D., Romagnani C., Chang H.D., Kruglov A., Mashreghi M.F., Shi W., Strowig T., Rutz S., ... , Kallies A., Scheffold A. (2024)
Correction to: c-Maf-dependent T(reg) cell control of intestinal T(H)17 cells and IgA establishes host-microbiota homeostasis (Nature Immunology, (2019), 20, 4, (471-481), 10.1038/s41590-019-0316-2)
Nature Immunology
DOI: 10.1038/s41590-024-01863-4 PubMed
Vialetto E., Miele S., Goren M.G., Yu J., Yu Y., Collias D., Beamud B., Osbelt L., Lourenco M., Strowig T., Brisse S., Barquist L., Qimron U., ... , Bikard D., Beisel C.L. (2024)
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide-and strain-dependent features influencing antimicrobial activity
Nucleic Acids Res.
DOI: 10.1093/nar/gkae281 HZI-Repositorium PubMed
Klee B., Diexer S., Horn J., Langer S., Wende M., Ortiz D., Bielecka A., Strowig T., ... , Mikolajczyk R., Gottschick C. (2024)
The impact of non-pharmaceutical interventions on community non-SARS-CoV-2 respiratory infections in preschool children
BMC Pediatrics, 24 (1)
DOI: 10.1186/s12887-024-04686-2 HZI-Repositorium PubMed
Zou M., Pezoldt J., Mohr J., Philipsen L., Leufgen A., Cerovic V., Wiechers C., Pils M., Ortiz D., Hao L., Yang J., Beckstette M., Dupont A., Hornef M., Dersch P., Strowig T., Müller A.J., ... , Raila J., Huehn J. (2024)
Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes
Cell Reports, 43 (5)
DOI: 10.1016/j.celrep.2024.114153 HZI-Repositorium PubMed
Almasi E.D.H., Knischewski N., Osbelt L., Muthukumarasamy U., el Mouali Y., Vialetto E., ... , Beisel C.L., Strowig T. (2024)
An adapted method for Cas9-mediated editing reveals the species-specific role of b
J.Bacteriol.
DOI: 10.1128/jb.00317-23 PubMed
Huang K.D., Amend L., Galvez E.J.C., Lesker T.R., de Oliveira R., Bielecka A., Blanco-Miguez A., Valles-Colomer M, Ruf I, Pasolli E, Buer J, Segata N, Esser S, ... , Strowig T, Kehrmann J (2024)
Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices
Cell Rep.Med.
DOI: 10.1016/j.xcrm.2024.101426 HZI-Repositorium PubMed
Kerlikowsky F., Müller M., Greupner T., Amend L., Strowig T., Hahn A. (2023)
Distinct Microbial Taxa Are Associated with LDL-Cholesterol Reduction after 12 Weeks of Lactobacillus plantarum Intake in Mild Hypercholesterolemia: Results of a Randomized Controlled Study
Probiotics Antimicrob.Proteins
DOI: 10.1007/s12602-023-10191-2 HZI-Repositorium PubMed
Tsakmaklis A., Farowski F., Zenner R., Lesker T.R., Strowig T., Schlößer H., Lehmann J., von Bergwelt-Baildon M., Mauch C., Schlaak M., Knuever J., Schweinsberg V., ... , Heinzerling L.M., Vehreschild M.J.G.T. (2023)
TIGIT+ NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients
BMC Cancer, 23 (1)
DOI: 10.1186/s12885-023-11551-5 HZI-Repositorium PubMed
Blanco-Miguez A., Galvez E.J.C., Pasolli E., De Filippis F., Amend L., Huang K.D., Manghi P., Lesker T.R., Riedel T., Cova L., Puncoochar M., Thomas A.M., Valles-Colomer M., Schober I., Hitch T.C.A., Clavel T., Berry S.E., Davies R., Wolf J., Spector T.D., Overmann J., Tett A., Ercolini D., ... , Segata N., Strowig T. (2023)
Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions
Cell Host.Microbe, 31 (11)
DOI: 10.1016/j.chom.2023.09.013 HZI-Repositorium PubMed
Ma J., Urgard E., Runge S., Classon C.H., Mathä L., Stark J.M., Cheng L., Alvarez J.A., von Zedtwitz S., Baleviciute A., Martinez Hoyer S., Li M., Gernand A.M., Osbelt L., Bielecka A.A., Lesker T.R., Huang H.J., Vrtala S., Boon L., Beyaert R., Adner M., Martinez Gonzalez I., Strowig T., Du J., Nylen S., ... , Rosshart S.P., Coquet J.M. (2023)
Laboratory mice with a wild microbiota generate strong allergic immune responses
Sci Immunol, 8 (87)
DOI: 10.1126/sciimmunol.adf7702 HZI-Repositorium PubMed
Hamad I., Van Broeckhoven J., Cardilli A., Hellings N., Strowig T., Lemmens S., ... , Hendrix S., Kleinewietfeld M. (2023)
Effects of Recombinant IL-13 Treatment on Gut Microbiota Composition and Functional Recovery after Hemisection Spinal Cord Injury in Mice
Nutrients, 15 (19)
DOI: 10.3390/nu15194184 HZI-Repositorium PubMed
Siracusa F., Schaltenberg N., Kumar Y., Lesker T.R., Steglich B., Liwinski T., Cortesi F., Frommann L., Diercks B.P., B+Ânisch F., Fischer A.W., Scognamiglio P., Pauly M.J., Casar C., Cohen Y., Pelczar P., Agalioti T., Delfs F., Worthmann A., Wahib R., Jagemann B., Mittr++cker H.W., Kretz O., Guse A.H., Izbicki J.R., Lassen K.G., Strowig T., Schweizer M., Villablanca E.J., Elinav E., Huber S., ... , Heeren J., Gagliani N. (2023)
Short-term dietary changes can result in mucosal and systemic immune depression
Nat.Immunol., 24 (9)
DOI: 10.1038/s41590-023-01587-x HZI-Repositorium PubMed
Essex M., Rios Rodriguez V, Rademacher J., Proft F., Löber U., Marko L., Pleyer U., Strowig T., Marchand J., Kirwan J.A., Siegmund B., ... , Forslund S.K., Poddubnyy D. (2023)
Spondyloarthritis, acute anterior uveitis, and Crohn's disease have both shared and distinct gut microbiota
Arthritis Rheumatol.
DOI: 10.1002/art.42658 PubMed
Harnack C., Berger H., Liu L., Mollenkopf H.J., Strowig T., Sigal M. (2023)
Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis
Gut Microbes, 15 (1)
DOI: 10.1080/19490976.2023.2233689 HZI-Repositorium PubMed
Liu X., Khalil A.E.M.M., Muthukumarasamy U., Onogi Y., Yan X., Singh I., Lopez-Gonzales E., Israel A., Serrano A.C., ... , Strowig T., Ussar S. (2023)
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
BMC Biol., 21 (1)
DOI: 10.1186/s12915-023-01629-8 HZI-Repositorium PubMed
Li D., Bühler M., Runft S., Gerold G., Marek K., Baumgärtner W., ... , Strowig T., Gerhauser I. (2023)
ASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler's murine encephalomyelitis virus
Sci.Rep., 13 (1)
DOI: 10.1038/s41598-023-38152-3 HZI-Repositorium PubMed
Saleh D.O., Horstmann J.A., Giralt-Zuniga M., Weber W., Kaganovitch E., Durairaj A.C., Klotzsch E., ... , Strowig T., Erhardt M. (2023)
SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner
PLoS.Pathog., 19 (6)
DOI: 10.1371/journal.ppat.1011451 HZI-Repositorium PubMed
Lourenco M., Osbelt L., Passet V., Gravey F., Megrian D., Strowig T., ... , Rodrigues C., Brisse S. (2023)
Phages against Noncapsulated Klebsiella pneumoniae: Broader Host range, Slower Resistance
Microbiol.Spectr.
DOI: 10.1128/spectrum.04812-22 HZI-Repositorium PubMed
Gui W., Hole M.J., Molinaro A., Edlund K., Jorgensen K.K., Su H., Begher-Tibbe B., Gaßler N., Schneider C.V., Muthukumarasamy U., Mohs A., Liao L., Jaeger J., Mertens C.J., Bergheim I., Strowig T., Hengstler J.G., Hov J.R., Marschall H.U., ... , Trautwein C., Schneider K.M. (2023)
Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis
Nat.Commun., 14 (1)
DOI: 10.1038/s41467-023-38840-8 HZI-Repositorium PubMed
Paschold L., Gottschick C., Langer S., Klee B., Diexer S., Aksentijevich I., Schultheiß C., Purschke O., Riese P., Trittel S., Haase R., Dressler F., Eberl W., Hübner J., Strowig T., Guzman C.A., ... , Mikolajczyk R., Binder M. (2023)
T cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort
Sci.Rep., 13 (1)
DOI: 10.1038/s41598-023-36144-x HZI-Repositorium
Zhao B., Osbelt L., Lesker T.R., Wende M., Galvez E.J.C., Hönicke L., Bublitz A., Greweling-Pils M.C., Grassl G.A., ... , Neumann-Schaal M., Strowig T. (2023)
Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacterrodentium infection in the absence of adaptive immunity
Cell Rep., 42 (6)
DOI: 10.1016/j.celrep.2023.112549 HZI-Repositorium PubMed
Fuchs M., Lamm-Schmidt V., Lence T., Sulzer J., Bublitz A., Wackenreuter J., Gerovac M., ... , Strowig T., Faber F. (2023)
A network of small RNAs regulates sporulation initiation in Clostridioides difficile
EMBO J
DOI: 10.15252/embj.2022112858 HZI-Repositorium PubMed
Manghi P., Blanco-Miguez A., Manara S., NabiNejad A., Cumbo F., Beghini F., Armanini F., Golzato D., Huang K.D., Thomas A.M., Piccinno G., Puncochar M., Zolfo M., Lesker T.R., Bredon M., Planchais J., Glodt J., Valles-Colomer M., Koren O., Pasolli E., Asnicar F., Strowig T., ... , Sokol H., Segata N. (2023)
MetaPhlAn 4 profiling of unknown species-level genome bins improves the characterization of diet-associated microbiome changes in mice
Cell Rep., 42 (5)
DOI: 10.1016/j.celrep.2023.112464 HZI-Repositorium PubMed
Bublitz A., Brauer M., Wagner S., Hofer W., Müsken M., Deschner F., Lesker T.R., Neumann-Schaal M., Paul L., Nübel U., Bartel J., Kany A.M., Zühlke D., Bernecker S., Jansen R., Sievers S., Riedel K., Herrmann J., Müller R., ... , Fuchs T.M., Strowig T. (2023)
The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection
Cell Host.Microbe
DOI: 10.1016/j.chom.2023.04.003 HZI-Repositorium PubMed
Su H., Haque M., Becker S., Edlund K., Duda J., Wang Q., Marschall H.U., Candels L.S., Mohamed M., Sj+Âland W., Liao L., Drexler S.A., Strowig T., Rahnenführer J., ... , Hengstler J.G., Hatting M. (2023)
Long-term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals
Liver International
DOI: 10.1111/liv.15587 HZI-Repositorium PubMed
Gilbert B.T.P., Lamacchia C., Amend L., Strowig T., Rodriguez E., ... , Palmer G., Finckh A. (2023)
Brief report: Assessment of mucosal barrier integrity using serological biomarkers in preclinical stages of rheumatoid arthritis
Front.Immunol., 14
DOI: 10.3389/fimmu.2023.1117742 HZI-Repositorium PubMed
Tintelnot J., Xu Y., Lesker T.R., Schönlein M., Konczalla L., Giannou A.D., Pelczar P., Kylies D., Puelles V.G., Bielecka A.A., Peschka M., Cortesi F., Riecken K., Jung M., Amend L., Bröring T.S., Trajkovic-Arsic M., Siveke J.T., Renné T., Zhang D., Boeck S., Strowig T., Uzunoglu F.G., Güngör C., Stein A., Izbicki J.R., Bokemeyer C., Sinn M., Kimmelman A.C., ... , Huber S., Gagliani N. (2023)
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Nature
DOI: 10.1038/s41586-023-05728-y HZI-Repositorium PubMed
Amend L., Gilbert B.T.P., Pelczar P., Böttcher M., Huber S., Witte T., ... , Finckh A., Strowig T. (2023)
Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases
Front.Cell.Infect.Microbiol., 12
DOI: 10.3389/fcimb.2022.1096211 HZI-Repositorium PubMed
Collias D., Vialetto E., Yu J., Co K., Almasi E., Rüttiger A.S., Achmedov T., ... , Strowig T., Beisel C.L. (2023)
Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria
Nat.Commun., 14 (1)
DOI: 10.1038/s41467-023-36283-9 HZI-Repositorium PubMed
Giannou A.D., Kempski J., Shiri A.M., Lücke J., Zhang T., Zhao L., Zazara D.E., Cortesi F., Riecken K., Amezcua Vesely M.C., Low J.S., Xu H., Kaffe E., Garcia-Perez L., Agalioti T., Yamada Y., Jungraithmayr W., Zigmond E., Karstens K.F., Steglich B., Wagner J., Konczalla L., Carambia A., Schulze K., von Felden J., May P., Briukhovetska D., Bedke T., Brockmann L., Starzonek S., Lange T., Koch C., Riethdorf S., Pelczar P., Böttcher M., Sabihi M., Huber F.J., Reeh M., Grass J.K., Wahib R., Seese H., Stüben B.O., Fard-Aghaie M., Duprée A., Scognamiglio P., Plitzko G., Meiners J., Soukou S., Wittek A., Manthey C., Maroulis I.C., Arck P.C., Perez D., Gao B., Zarogiannis S.G., Strowig T., Pasqualini R., Arap W., Gosálvez J.S., Kobold S., Prinz I., Guse A.H., Tachezy M., Ghadban T., Heumann A., Li J., Melling N., Mann O., Izbicki J.R., Pantel K., Schumacher U., Lohse A.W., Flavell R.A., ... , Gagliani N., Huber S. (2023)
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Immunity, 56 (1)
DOI: 10.1016/j.immuni.2022.12.014 HZI-Repositorium PubMed
Hankel J., Sander S., Muthukumarasamy U., Strowig T., Kamphues J., ... , Jung K., Visscher C. (2022)
Microbiota of vaccinated and non-vaccinated clinically inconspicuous and conspicuous piglets under natural Lawsonia intracellularis infection
Front.Vet.Sci., 9
DOI: 10.3389/fvets.2022.1004506 HZI-Repositorium PubMed
Thriene K., Stanislas V., Amend L., Strowig T., Michels K.B. (2022)
Assessment of the Gut Microbiota during Juice Fasting with and without Inulin Supplementation: A Feasibility Study in Healthy Volunteers
Foods, 11 (22)
DOI: 10.3390/foods11223673 HZI-Repositorium PubMed
Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A. (2022)
Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly
Nat.Commun., 13 (1)
DOI: 10.1038/s41467-022-34487-z HZI-Repositorium PubMed
Hankel J., Kittler S., Chuppava B., Galvez E., Strowig T., Becker A., Von Köckritz-Blickwede M., ... , Plötz M., Visscher C. (2022)
Luminal and mucosa-associated caecal microbiota of chickens after experimental Campylobacter jejuni infection in the absence of Campylobacter-specific phages of group II and III
Microb.Genomics, 8 (10)
DOI: 10.1099/mgen.0.000874 HZI-Repositorium PubMed
Afrizal A., Jennings S.A.V., Hitch T.C.A., Riedel T., Basic M., Panyot A., Treichel N., Hager F.T., Wong E.O., Wolter B., Viehof A., von Strempel A., Eberl C., Buhl E.M., Abt B., Bleich A., Tolba R., Blank L.M., Navarre W.W., Kiessling F., Horz H.P., Torow N., Cerovic V., Stecher B., Strowig T., ... , Overmann J., Clavel T. (2022)
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities
Cell Host.Microbe
DOI: 10.1016/j.chom.2022.09.011 HZI-Repositorium PubMed
Hankel J., Chuppava B., Wilke V., Hartung C.B., Muthukumarasamy U., Strowig T., Bach Knudsen K.E., ... , Kamphues J., Visscher C. (2022)
High Dietary Intake of Rye Affects Porcine Gut Microbiota in a Salmonella Typhimurium Infection Study
Plants, 11 (17)
DOI: 10.3390/plants11172232 HZI-Repositorium PubMed
Hitch T.C.A., Bisdorf K., Afrizal A., Riedel T., Overmann J., ... , Strowig T., Clavel T. (2022)
A taxonomic note on the genus Prevotella: Description of four novel genera and emended description of the genera Hallella and Xylanibacter
Syst.Appl.Microbiol., 45 (6)
DOI: 10.1016/j.syapm.2022.126354 HZI-Repositorium PubMed
Pausder A., Mras P., Hoenicke L., Waldburg N., Lesker T.R., Schreiber J., Strowig T., ... , Boehme J.D., Bruder D. (2022)
Altered nasal microbiota in asthmatic patients is not related to changes in secretory immunity in the nasopharynx
Clin.Exp.Allergy
DOI: 10.1111/cea.14200 HZI-Repositorium PubMed
French T., Steffen J., Glas A., Osbelt L., Strowig T., Schott B.H., ... , Schüler T., Dunay I.R. (2022)
Persisting Microbiota and Neuronal Imbalance Following T. gondii Infection Reliant on the Infection Route
Front.Immunol., 13
DOI: 10.3389/fimmu.2022.920658 HZI-Repositorium PubMed
Melcher C., Yu J., Duong V.H.H., Westphal K., Helmi Siasi Farimany N., Shaverskyi A., Zhao B., Strowig T., Glage S., Brand K., Chan A.C., ... , Föger N., Lee K.H. (2022)
B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation
Cell Rep., 40 (2)
DOI: 10.1016/j.celrep.2022.111051 HZI-Repositorium PubMed
Schneider K.M., Mohs A., Gui W., Galvez E.J.C., Candels L.S., Hoenicke L., Muthukumarasamy U., Holland C.H., Elfers C., Kilic K., Schneider C.V., Schierwagen R., Strnad P., Wirtz T.H., Marschall H.U., Latz E., Lelouvier B., Saez-Rodriguez J., de Vos W., Strowig T., ... , Trebicka J., Trautwein C. (2022)
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment
Nat.Commun., 13 (1)
DOI: 10.1038/s41467-022-31312-5 HZI-Repositorium PubMed
Lucassen A., Hankel J., Finkler-Schade C., Osbelt L., Strowig T., ... , Visscher C., Schuberth H.J. (2022)
Feeding a Saccharomyces cerevisiae Fermentation Product (Olimond BB) Does Not Alter the Fecal Microbiota of Thoroughbred Racehorses
Animals.(Basel), 12 (12)
DOI: 10.3390/ani12121496 HZI-Repositorium PubMed
Meyer F., Fritz A., Deng Z.L., Koslicki D., Lesker T.R., Gurevich A., Robertson G., Alser M., Antipov D., Beghini F., Bertrand D., Brito J.J., Brown C.T., Buchmann J., Buluc A., Chen B., Chikhi R., Clausen P.T.L.C., Cristian A., Dabrowski P.W., Darling A.E., Egan R., Eskin E., Georganas E., Goltsman E., Gray M.A., Hansen L.H., Hofmeyr S., Huang P., Irber L., Jia H., Jorgensen T.S., Kieser S.D., Klemetsen T., Kola A., Kolmogorov M., Korobeynikov A., Kwan J., LaPierre N., Lemaitre C., Li C., Limasset A., Malcher-Miranda F., Mangul S., Marcelino V.R., Marchet C., Marijon P., Meleshko D., Mende D.R., Milanese A., Nagarajan N., Nissen J., Nurk S., Oliker L., Paoli L., Peterlongo P., Piro V.C., Porter J.S., Rasmussen S., Rees E.R., Reinert K., Renard B., Robertsen E.M., Rosen G.L., Ruscheweyh H.J., Sarwal V., Segata N., Seiler E., Shi L., Sun F., Sunagawa S., Sorensen S.J., Thomas A., Tong C., Trajkovski M., Tremblay J., Uritskiy G., Vicedomini R., Wang Z., Warren A., Willassen N.P., Yelick K., You R., Zeller G., Zhao Z., Zhu S., Zhu J., Garrido-Oter R., Gastmeier P., Hacquard S., Häussler S., Khaledi A., Maechler F., Mesny F., Radutoiu S., Schulze-Lefert P., Smit N., Strowig T., Bremges A., ... , Sczyrba A., McHardy A.C. (2022)
Critical Assessment of Metagenome Interpretation: the second round of challenges
Nature Methods, 19 (4)
DOI: 10.1038/s41592-022-01431-4 HZI-Repositorium PubMed
Kini A., Zhao B., Basic M., Roy U., Iljazovic A., Odak I., Ye Z., Riederer B., Di Stefano G., Römermann D., Koenecke C., Bleich A., ... , Strowig T., Seidler U. (2022)
Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect
Gut Microbes, 14 (1)
DOI: 10.1080/19490976.2022.2041943 HZI-Repositorium PubMed
Pausder A., Fricke J., Schughart K., Schreiber J., Strowig T., ... , Bruder D., Boehme J.D. (2021)
Exogenous and Endogenous Triggers Differentially Stimulate Pigr Expression and Antibacterial Secretory Immunity in the Murine Respiratory Tract
Lung
DOI: 10.1007/s00408-021-00498-8 HZI-Repositorium PubMed
Li J., Gálvez E.J.C., Amend L., Almasi A., Iljazovic A., Lesker T.R., Bielecka A.A., ... , Schorr E.M., Strowig T. (2021)
A versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems
Embo Journal, 40 (23)
DOI: 10.15252/embj.2021108287 HZI-Repositorium PubMed
Muschaweck M., Kopplin L., Ticconi F., Schippers A., Iljazovic A., Galvez E.J.C., Abdallah A.T., Wagner N., Costa I.G., ... , Strowig T., Pabst O. (2021)
Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon
Immunity.
DOI: 10.1016/j.immuni.2021.08.014 HZI-Repositorium PubMed
Osbelt L., Wende M., Almasi A., Derksen E., Muthukumarasamy U., Lesker T.R., Galvez E.J.C., Pils M.C., Schalk E., Chhatwal P., Farber J., Neumann-Schaal M., Fischer T., ... , Schlüter D., Strowig T. (2021)
Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition
Cell Host.Microbe
DOI: 10.1016/j.chom.2021.09.003 HZI-Repositorium PubMed
Schneider K.M., Candels L.S., Hov J.R., Myllys M., Hassan R., Schneider C.V., Wahlström A., Mohs A., Zühlke S., Liao L., Elfers C., Kilic K., Henricsson M., Molinaro A., Hatting M., Zaza A., Drasdo D., Frissen M., Devlin A.S., Gálvez E.J.C., Strowig T., Karlsen T.H., Hengstler J.G., Marschall H.U., ... , Ghallab A., Trautwein C. (2021)
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
Nature Meta., 3 (9)
DOI: 10.1038/s42255-021-00452-1 PubMed
Roy U., de Oliveira R.S., Galvez E.J.C., Gronow A., Basic M., Perez L.G., Gagliani N., Bleich A., ... , Huber S., Strowig T. (2021)
Induction of IL-22-Producing CD4+ T Cells by Segmented Filamentous Bacteria Independent of Classical Th17 Cells
Front.Immunol., 12
DOI: 10.3389/fimmu.2021.671331 HZI-Repositorium PubMed
Plaza-Sirvent C., Zhao B., Bronietzki A.W., Pils M.C., Tafrishi N., Schuster M., ... , Strowig T., Schmitz I. (2021)
A Central Role for Atg5 in Microbiota-Dependent Foxp3(+) RORg[gamma]t(+) Treg Cell Preservation to Maintain Intestinal Immune Homeostasis
Front Immunol., 12
DOI: 10.3389/fimmu.2021.705436 HZI-Repositorium PubMed
Hankel J., Bodmann B., Todte M., Galvez E., Strowig T., Radko D., ... , Antakli A., Visscher C. (2021)
Comparison of Chicken Cecal Microbiota after Metaphylactic Treatment or Following Administration of Feed Additives in a Broiler Farm with Enterococcal Spondylitis History
Pathogens., 10 (8)
DOI: 10.3390/pathogens10081068 HZI-Repositorium PubMed
Delacher M., Simon M., Sanderink L., Hotz-Wagenblatt A., Wuttke M., Schambeck K., Schmidleithner L., Bittner S., Pant A., Ritter U., Hehlgans T., Riegel D., Schneider V., Groeber-Becker F.K., Eigenberger A., Gebhard C., Strieder N., Fischer A., Rehli M., Hoffmann P., Edinger M., Strowig T., Hühn J., Schmidl C., Werner J.M., Prantl L., Brors B., ... , Imbusch C.D., Feuerer M. (2021)
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
Immunity, 54 (4)
DOI: 10.1016/j.immuni.2021.03.007 HZI-Repositorium PubMed
Maifeld A., Bartolomaeus H., Löber U., Avery E.G., Steckhan N., Markó L., Wilck N., Hamad I., Susnjar U., Mähler A., Hohmann C., Chen C.Y., Cramer H., Dobos G., Lesker T.R., Strowig T., Dechend R., Bzdok D., Kleinewietfeld M., Michalsen A., ... , Müller D.N., Forslund S.K. (2021)
Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients
Nat Commun., 12 (1)
DOI: 10.1038/s41467-021-22097-0 HZI-Repositorium PubMed
Wiechers C., Zou M., Galvez E., Beckstette M., Ebel M., Strowig T., ... , Huehn J., Pezoldt J. (2021)
The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes
Cell Mol.Immunol., 18 (5)
DOI: 10.1038/s41423-021-00647-2 HZI-Repositorium PubMed
Song Y., Shan L., Gbyli R., Liu W., Strowig T., Patel A., Fu X., Wang X., Xu M.L., Gao Y., Qin A., Bruscia E.M., Tebaldi T., Biancon G., Mamillapalli P., Urbonas D., Eynon E., Gonzalez D.G., Chen J., Krause D.S., Alderman J., ... , Halene S., Flavell R.A. (2021)
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells
Science, 371 (6533)
DOI: 10.1126/science.abe2485 HZI-Repositorium PubMed
Schneider K.M., Elfers C., Ghallab A., Schneider C.V., Galvez E.J.C., Mohs A., Gui W., Candels L.S., Wirtz T.H., Zuehlke S., Spiteller M., Myllys M., Roulet A., Ouzerdine A., Lelouvier B., Kilic K., Liao L., Nier A., Latz E., Bergheim I., Thaiss C.A., Hengstler J.G., ... , Strowig T., Trautwein C. (2021)
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury
Cell.Mol.Gastroenterol.Hepatol., 11 (4)
DOI: 10.1016/j.jcmgh.2020.11.002 HZI-Repositorium PubMed
Regen T., Isaac S., Amorim A., Nunez N.G., Hauptmann J., Shanmugavadivu A., Klein M., Sankowski R., Mufazalov I.A., Yogev N., Huppert J., Wanke F., Witting M., Grill A., Gálvez E.J.C., Nikolaev A., Blanfeld M., Prinz I., Schmitt-Kopplin P., Strowig T., Reinhardt C., Prinz M., Bopp T., Becher B., ... , Ubeda C., Waisman A. (2021)
IL-17 controls central nervous system autoimmunity through the intestinal microbiome
Sci.Immunol., 6 (56)
DOI: 10.1126/sciimmunol.aaz6563 HZI-Repositorium PubMed
Iljazovic A., Amend L., Galvez E.J.C., de Oliveira R., Strowig T. (2021)
Modulation of inflammatory responses by gastrointestinal Prevotella spp. - From associations to functional studies
Int.J.Med.Microbiol., 311 (2)
DOI: 10.1016/j.ijmm.2021.151472 HZI-Repositorium PubMed
Koeninger L., Osbelt L., Berscheid A., Wendler J., Berger J., Hipp K., Lesker T.R., Pils M.C., Malek N.P., Jensen B.A.H., Brötz-Oesterhelt H., ... , Strowig T., Wehkamp J. (2021)
Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota
Commun.Biolog., 4 (1)
DOI: 10.1038/s42003-020-01582-0 HZI-Repositorium PubMed
Wylensek D., Hitch T.C.A., Riedel T., Afrizal A., Kumar N., Wortmann E., Liu T., Devendran S., Lesker T.R., Hernández S.B., Heine V., Buhl E.M., D'Agostino M., Cumbo F., Fischöder T., Wyschkon M., Looft T., Parreira V.R., Abt B., Doden H.L., Ly L., Alves J.M.P., Reichlin M., Flisikowski K., Suarez L.N., Neumann A.P., Suen G., de Wouters T., Rohn S., Lagkouvardos I., len-Vercoe E., Spröer C., Bunk B., Taverne-Thiele A.J., Giesbers M., Wells J.M., Neuhaus K., Schnieke A., Cava F., Segata N., Elling L., Strowig T., Ridlon J.M., Gulder T.A.M., ... , Overmann J., Clavel T. (2020)
A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity
Nat.Commun., 11 (1)
DOI: 10.1038/s41467-020-19929-w HZI-Repositorium PubMed
Wells P.M., Adebayo A.S., Bowyer R.C.E., Freidin M.B., Finckh A., Strowig T., Lesker T.R., Apizar-Rodriguez D., Gilbert B., Kirkham B., Cope A.P., ... , Steves C.J., Williams F.M.K. (2020)
Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study
Lancet Rheumatol., 2 (7)
DOI: 10.1016/S2665-9913(20)30064-3 HZI-Repositorium PubMed
Galvez E.J.C., Iljazovic A., Amend L., Lesker T.R., Renault T., Thiemann S., Hao L., Roy U., Gronow A., ... , Charpentier E., Strowig T. (2020)
Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp
Cell Host.Microbe, 28 (6)
DOI: 10.1016/j.chom.2020.09.012 HZI-Repositorium PubMed
Dürholz K., Hofmann J., Iljazovic A., Häger J., Lucas S., Sarter K., Strowig T., Bang H., Rech J., ... , Schett G., Zaiss M.M. (2020)
Dietary short-term fiber interventions in arthritis patients increase systemic scfa levels and regulate inflammation
Nutrients, 12 (10)
DOI: 10.3390/nu12103207 HZI-Repositorium PubMed
Wilharm A., Brigas H.C., Sandrock I., Ribeiro M., Amado T., Reinhardt A., Demera A., Hoenicke L., Strowig T., Carvalho T., ... , Prinz I., Ribot J.C. (2020)
Correction: Microbiota-dependent expansion of testicular IL-17-producing Vg[gamma]6(+) g[gamma]d[delta]T cells upon puberty promotes local tissue immune surveillance
Mucosal.Immunol., 14 (1)
DOI: 10.1038/s41385-020-00346-7 HZI-Repositorium PubMed
Hankel J., El-Wahab A.A., Grone R., Keller B., Galvez E., ... , Strowig T., Visscher C. (2020)
Faecal microbiota of dogs offered a vegetarian diet with or without the supplementation of feather meal and either cornmeal, rye or fermented rye: A preliminary study
Microorg., 8 (9)
DOI: 10.3390/microorganisms8091363 HZI-Repositorium PubMed
Wilharm A., Brigas H.C., Sandrock I., Ribeiro M., Amado T., Reinhardt A., Demera A., Hoenicke L., Strowig T., Carvalho T., ... , Prinz I., Ribot J.C. (2020)
Microbiota-dependent expansion of testicular IL-17-producing Vg[gamma]6+ g[gamma]d[delta] T cells upon puberty promotes local tissue immune surveillance
Mucosal Immunol., 14 (1)
DOI: 10.1038/s41385-020-0330-6 HZI-Repositorium PubMed
Kempski J., Giannou A.D., Riecken K., Zhao L., Steglich B., Lücke J., Garcia-Perez L., Karstens K.F., Wöstemeier A., Nawrocki M., Pelczar P., Witkowski M., Nilsson S., Konczalla L., Shiri A.M., Kempska J., Wahib R., Brockmann L., Huber P., Gnirck A.-C., Turner J.-E., Zazara D.E., Arck P.C., Stein A., Simon R., Daubmann A., Meiners J., Perez D., Strowig T., Koni P., Kruglov A.A., Sauter G., Izbicki J.R., Guse A.H., Roesch T., Lohse A.W., Flavell R.A., ... , Gagliani N., Huber S. (2020)
IL22BP Mediates the Anti-Tumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans
Gastroenterology, 159 (4)
DOI: 10.1053/j.gastro.2020.06.033 HZI-Repositorium PubMed
Iljazovic A., Roy U., Gálvez E.J.C., Lesker T.R., Zhao B., Gronow A., Amend L., Will S.E., Hofmann J.D., Pils M.C., Schmidt-Hohagen K., ... , Neumann-Schaal M., Strowig T. (2020)
Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation
Mucosal.Immunol., 14 (1)
DOI: 10.1038/s41385-020-0296-4 HZI-Repositorium PubMed
Carriche G.M., Almeida L., Stüve P., Velasquez L., Dhillon-LaBrooy A., Roy U., Lindenberg M., Strowig T., Plaza-Sirvent C., Schmitz I., Lochner M., ... , Simon A.K., Sparwasser T. (2021)
Regulating T cell differentiation through the polyamine spermidine
J.Allergy Clin.Immunol., 147 (1)
DOI: 10.1016/j.jaci.2020.04.037 PubMed
Bunte S., Grone R., Keller B., Keller C., Galvez E., Strowig T., ... , Kamphues J., Hankel J. (2020)
Intestinal microbiota of fattening pigs offered non-fermented and fermented liquid feed with and without the supplementation of non-fermented coarse cereals
Microorg., 8 (5)
DOI: 10.3390/microorganisms8050638 HZI-Repositorium PubMed
Tajik N., Frech M., Schulz O., Schalter F., Lucas S., Azizov V., Durholz K., Steffen F., Omata Y., Rings A., Bertog M., Rizzo A., Iljazovic A., Basic M., Kleyer A., Culemann S., Kronke G., Luo Y., Uberla K., Gaipl U.S., Frey B., Strowig T., Sarter K., Bischoff S.C., Wirtz S., Canete J.D., Ciccia F., ... , Schett G., Zaiss M.M. (2020)
Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis
Nat.Commun., 11 (1)
DOI: 10.1038/s41467-020-15831-7 HZI-Repositorium PubMed
Roje B., Elek A., Palada V., Bom J., Iljazovic A., Simic A., Susak L., Vilovic K., Strowig T., ... , Vlahovicek K., Terzic J. (2020)
Microbiota Alters Urinary Bladder Weight and Gene Expression
Microorganisms., 8 (3)
DOI: 10.3390/microorganisms8030421 HZI-Repositorium PubMed
Osbelt L., Thiemann S., Smit N., Lesker T.R., Schröter M., Galvez E.J.C., Schmidt-Hohagen K., Pils M.C., Mühlen S., Dersch P., Hiller K., Schluter D., ... , Neumann-Schaal M., Strowig T. (2020)
Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production
PLoS.Pathog., 16 (3)
DOI: 10.1371/journal.ppat.1008448 HZI-Repositorium PubMed
Lesker T.R., Durairaj A.C., Gálvez E.J.C., Lagkouvardos I., Baines J.F., Clavel T., Sczyrba A., ... , McHardy A.C., Strowig T. (2020)
An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome
Cell Rep., 30 (9)
DOI: 10.1016/j.celrep.2020.02.036 HZI-Repositorium PubMed
Bank U., Deiser K., Plaza-Sirvent C., Osbelt L., Witte A., Knop L., Labrenz R., Jänsch R., Richter F., Biswas A., Zenclussen A.C., Vivier E., Romagnani C., Kühl A.A., Dunay I.R., Strowig T., ... , Schmitz I., Schüler T. (2020)
c-FLIP is crucial for IL-7/IL-15-dependent NKp46(+) ILC development and protection from intestinal inflammation in mice
Nat.Commun., 11 (1)
DOI: 10.1038/s41467-020-14782-3 HZI-Repositorium PubMed
Al-Kershi S., Bhayadia R., Ng M., Verboon L., Emmrich S., Gack L., Schwarzer A., Strowig T., ... , Heckl D., Klusmann J.H. (2019)
The stem cell-specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia
Blood Adv., 3 (24)
DOI: 10.1182/bloodadvances.2019032029 HZI-Repositorium PubMed
Alpizar Rodriguez D., Lesker T.R., Gilbert B., Strowig T., Finckh A. (2021)
Response to: 'Non-causal association of gut microbiome on the risk of rheumatoid arthritis: a Mendelian randomisation study' by Inamo
Ann.Rheum.Dis., 80 (7)
DOI: 10.1136/annrheumdis-2019-216637 HZI-Repositorium PubMed
Wiesenborn D.S., Galvez E.J.C., Spinel L., Victoria B., Allen B., Schneider A., Gesing A., Al-Regaiey K.A., Strowig T., ... , Schäfer K.H., Masternak M.M. (2020)
The role of Ames dwarfism and calorie restriction on gut microbiota
J.Gerontol.A Biol.Sci.Med.Sci., 75 (7)
DOI: 10.1093/gerona/glz236 HZI-Repositorium PubMed
Hankel J., Jung K., Kuder H., Keller B., Keller C., Galvez E., ... , Strowig T., Visscher C. (2019)
Caecal Microbiota of Experimentally Campylobacter jejuni-Infected Chickens at Different Ages
Front Microbiol., 10
DOI: 10.3389/fmicb.2019.02303 HZI-Repositorium PubMed
Lipinski S., Pfeuffer S., Arnold P., Treitz C., Aden K., Ebsen H., Falk-Paulsen M., Gisch N., Fazio A., Kuiper J., Luzius A., Billmann-Born S., Schreiber S., Nunez G., Beer H.D., Strowig T., Lamkanfi M., ... , Tholey A., Rosenstiel P. (2019)
Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles
EMBO J., 38 (20)
DOI: 10.15252/embj.2018101266 HZI-Repositorium PubMed
Strowig T., Thiemann S., Diefenbach A. (2018)
Microbiome and gut immunity: Innate immune cells
(8)
DOI: 10.1007/978-3-319-90545-7_8 PubMed
Liao L., Schneider K.M., Galvez E.J.C., Frissen M., Marschall H.U., Su H., Hatting M., Wahlström A., Haybaeck J., Puchas P., Mohs A., Peng J., Bergheim I., Nier A., Hennings J., Reissing J., Zimmermann H.W., Longerich T., Strowig T., Liedtke C., ... , Cubero F.J., Trautwein C. (2019)
Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis
GUT, 68 (8)
DOI: 10.1136/gutjnl-2018-316670 PubMed
Visscher C., Hankel J., Nies A., Keller B., Galvez E., Strowig T., ... , Keller C., Breves G. (2019)
Performance, Fermentation Characteristics and Composition of the Microbiome in the Digest of Piglets Kept on a Feed With Humic Acid-Rich Peat
Front Vet.Sci., 6 (Febrary)
DOI: 10.3389/fvets.2019.00029 HZI-Repositorium
Mamareli P., Kruse F., Friedrich C., Smit N., Strowig T., ... , Sparwasser T., Lochner M. (2019)
Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile
Eur.J.Immunol, 49 (5)
DOI: 10.1002/eji.201848022
Neumann C., Blume J., Roy U., Teh P.P., Vasanthakumar A., Beller A., Liao Y., Heinrich F., Arenzana T.L., Hackney J.A., Eidenschenk C., Gálvez E.J.C., Stehle C., Heinz G.A., Maschmeyer P., Sidwell T., Hu Y., Amsen D., Romagnani C., Chang H.D., Kruglov A., Mashreghi M.F., Shi W., Strowig T., Rutz S., ... , Kallies A., Scheffold A. (2019)
c-Maf-dependent T reg cell control of intestinal T H 17 cells and IgA establishes host-microbiota homeostasis
Nat.Immunol.
DOI: 10.1038/s41590-019-0316-2 PubMed
Lagkouvardos I., Lesker T.R., Hitch T.C.A., Gálvez E.J.C., Smit N., Neuhaus K., Wang J., Baines J.F., Abt B., Stecher B., Overmann J., ... , Strowig T., Clavel T. (2019)
Sequence and cultivation study of Muribaculaceae reveals novel species, host preference, and functional potential of this yet undescribed family
Microbiome, 7 (1)
DOI: 10.1186/s40168-019-0637-2 HZI-Repositorium PubMed
Alpizar-Rodriguez D., Lesker T.R., Gronow A., Gilbert B., Raemy E., Lamacchia C., Gabay C., ... , Finckh A., Strowig T. (2019)
Prevotella copri in individuals at risk for rheumatoid arthritis
Ann.Rheum.Dis., 78 (5)
DOI: 10.1136/annrheumdis-2018-214514 HZI-Repositorium PubMed
Mathies F., Steffens N., Kleinschmidt D., Stuhlmann F., Huber F.J., Roy U., Meyer T., Luetgehetmann M., von Petersdorff M., Seiz O., Herkel J., Schramm C., Flavell R.A., Gagliani N., Krebs C., Panzer U., Abdullah Z., Strowig T., ... , Bedke T., Huber S. (2018)
Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3(+) Regulatory T Cells
J.Immunol., 201 (12)
DOI: 10.4049/jimmunol.1800711
Pezoldt J., Pasztoi M., Zou M., Wiechers C., Beckstette M., Thierry G.R., Vafadarnejad E., Floess S., Arampatzi P., Buettner M., Schweer J., Fleissner D., Vital M., Pieper D.H., Basic M., Dersch P., Strowig T., Hornef M., Bleich A., Bode U., Pabst O., Bajenoff M., ... , Saliba A.E., Hühn J. (2018)
Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes
Nat.Commun., 9 (1)
DOI: 10.1038/s41467-018-06423-7 HZI-Repositorium
Kindt A., Liebisch G., Clavel T., Haller D., Hörmannsperger G., Yoon H., Kolmeder D., Sigruener A., Krautbauer S., Seeliger C., Ganzha A., Schweizer S., Morisset R., Strowig T., Daniel H., Helm D., Küster B., ... , Krumsiek J., Ecker J. (2018)
The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
Nat.Commun., 9 (1)
DOI: 10.1038/s41467-018-05767-4
Suwandhi L., Hausmann S., Braun A., Gruber T., Heinzmann S.S., Gálvez E.J.C., Buck A., Legutko B., Israel A., Feuchtinger A., Haythorne E., Staiger H., Heni M., Häring H.-U., Schmitt-Kopplin P., Walch A., Cáceres C.G., Tschöp M.H., Rutter G.A., Strowig T., ... , Elsner M., Ussar S. (2018)
Chronic D-serine supplementation impairs insulin secretion
Molecular Metabolism, 15 (September)
DOI: 10.1016/j.molmet.2018.07.002 HZI-Repositorium PubMed
Just S., Mondot S., Ecker J., Wegner K., Rath E., Gau L., Streidl T., Hery-Arnaud G., Schmidt S., Lesker T.R., Bieth V., Dunkel A., Strowig T., Hofmann T., Haller D., Liebisch G., ... , Rohn S., Lepage P. (2018)
The gut microbiota drives the impact of bile acids and fat source in diet on mouse metabolism
Microbiome, 6 (1)
DOI: 10.1186/s40168-018-0510-8 HZI-Repositorium PubMed
Schneider K.M., Wirtz T.H., Kroy D., Albers S., Neumann U.P., Strowig T., ... , Sellge G., Trautwein C. (2018)
Successful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation
Case.Rep.Gastroenterol., 12 (1)
DOI: 10.1159/000481937 HZI-Repositorium PubMed
Elinav E., Henao-Mejia J., Strowig T., Flavell R. (2018)
NLRP6 and Dysbiosis: Avoiding the Luring Attraction of Over-Simplification
Immunity, 48 (4)
DOI: 10.1016/j.immuni.2018.04.002 HZI-Repositorium PubMed
Heine W., Beckstette M., Heroven A.K., Thiemann S., Heise U., Nuss A.M., Pisano F., ... , Strowig T., Dersch P. (2018)
Loss of CNFY toxin-induced inflammation drives Yersinia pseudotuberculosis into persistency
PLoS.Pathog., 14 (2)
DOI: 10.1371/journal.ppat.1006858 HZI-Repositorium
Galvez E.J.C., Iljazovic A., Gronow A., Flavell R., Strowig T. (2017)
Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure
Cell Rep., 21 (13)
DOI: 10.1016/j.celrep.2017.12.027 HZI-Repositorium PubMed
Lucas S., Omata Y., Hofmann J., Bottcher M., Iljazovic A., Sarter K., Albrecht O., Schulz O., Krishnacoumar B., Kronke G., Herrmann M., Mougiakakos D., Strowig T., ... , Schett G., Zaiss M.M. (2018)
Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
Nat.Commun., 9 (1)
DOI: 10.1038/s41467-017-02490-4 HZI-Repositorium
Herndler-Brandstetter D., Shan L., Yao Y., Stecher C., Plajer V., Lietzenmayer M., Strowig T., de Zoete M.R., Palm N.W., Chen J., Blish C.A., Frleta D., Gurer C., Macdonald L.E., Murphy A.J., Yancopoulos G.D., ... , Montgomery R.R., Flavell R.A. (2017)
Humanized mouse model supports development, function, and tissue residency of human natural killer cells
Proc.Natl.Acad.Sci.U.S.A., 114 (45)
DOI: 10.1073/pnas.1705301114 HZI-Repositorium PubMed
Roy U., Gàlvez E.J.C., Iljazovic A., Lesker T.R., Blazejewski A.J., Pils M.C., Heise U., Huber S., ... , Flavell R.A., Strowig T. (2017)
Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells
Cell Reports, 21 (4)
DOI: 10.1016/j.celrep.2017.09.097 HZI-Repositorium PubMed
Fabiani F.D., Renault T.T., Peters B., Dietsche T., Galvez E.J.C., Guse A., Freier K., Charpentier E., Strowig T., Franz-Wachtel M., Macek B., Wagner S., ... , Hensel M., Erhardt M. (2017)
A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum
PLoS Biol., 15 (8)
DOI: 10.1371/journal.pbio.2002267 HZI-Repositorium
Blazejewski A.J., Thiemann S., Schenk A., Pils M.C., Galvez E.J.C., Roy U., Heise U., de Zoete M.R., ... , Flavell R.A., Strowig T. (2017)
Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation
Cell Rep., 19 (11)
DOI: 10.1016/j.celrep.2017.05.058 HZI-Repositorium PubMed
Thiemann S., Smit N., Roy U., Lesker T.R., Galvez E.J.C., Helmecke J., Basic M., Bleich A., Goodman A.L., Kalinke U., Flavell R.A., ... , Erhardt M., Strowig T. (2017)
Enhancement of IFNgamma Production by Distinct Commensals Ameliorates Salmonella-Induced Disease
Cell Host.Microbe, 21 (6)
DOI: 10.1016/j.chom.2017.05.005 HZI-Repositorium PubMed
Friedrich C., Mamareli P., Thiemann S., Kruse F., Wang Z., Holzmann B., Strowig T., ... , Sparwasser T., Lochner M. (2017)
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium
PLoS Pathog., 13 (5)
DOI: 10.1371/journal.ppat.1006357 HZI-Repositorium PubMed
Rueckert C., Rand U., Roy U., Kasmapour B., Strowig T., Guzmán C.A. (2017)
Cyclic dinucleotides modulate induced type I IFN responses in innate immune cells by degradation of STING
FASEB J., 31 (7)
DOI: 10.1096/fj.201601093R PubMed
Yu H., Borsotti C., Schickel J.N., Zhu S., Strowig T., Eynon E.E., Frleta D., Gurer C., Murphy A.J., Yancopoulos G.D., Meffre E., ... , Manz M.G., Flavell R.A. (2017)
A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production
Blood, 129 (8)
DOI: 10.1182/blood-2016-04-709584 HZI-Repositorium PubMed
Horstmann J.A., Zschieschang E., Truschel T., de Diego J., Lunelli M., Rohde M., May T., Strowig T., Stradal T., ... , Kolbe M., Erhardt M. (2017)
Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonization
Cell Microbiol., 19 (8)
DOI: 10.1111/cmi.12739 HZI-Repositorium PubMed
Hu B., Jin C., Li H.B., Tong J., Ouyang X., Cetinbas N.M., Zhu S., Strowig T., Lam F.C., Zhao C., Henao-Mejia J., Yilmaz O., Fitzgerald K.A., Eisenbarth S.C., ... , Elinav E., Flavell R.A. (2016)
The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury
Science, 354 (6313)
DOI: 10.1126/science.aaf7532 HZI-Repositorium PubMed
Pelczar P., Witkowski M., Perez L.G., Kempski J., Hammel A.G., Brockmann L., Kleinschmidt D., Wende S., Haueis C., Bedke T., Witkowski M., Krasemann S., Steurer S., Booth C.J., Busch P., König A., Rauch U., Benten D., Izbicki J.R., Rösch T., Lohse A.W., Strowig T., Gagliani N., ... , Flavell R.A., Huber S. (2016)
A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease
Science, 354 (6310)
DOI: 10.1126/science.aah5903 PubMed
Thiemann S., Smit N., Strowig T. (2016)
Antibiotics and the Intestinal Microbiome : Individual Responses, Resilience of the Ecosystem, and the Susceptibility to Infections
Curr Top.Microbiol.Immunol., 398 (6)
DOI: 10.1007/82_2016_504 PubMed
Rausch P., Basic M., Batra A., Bischoff S.C., Blaut M., Clavel T., Glasner J., Gopalakrishnan S., Grassl G.A., Gunther C., Haller D., Hirose M., Ibrahim S., Loh G., Mattner J., Nagel S., Pabst O., Schmidt F., Siegmund B., Strowig T., Volynets V., Wirtz S., Zeissig S., Zeissig Y., ... , Bleich A., Baines J.F. (2016)
Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities
Int.J Med.Microbiol., 306 (5)
DOI: 10.1016/j.ijmm.2016.03.004 HZI-Repositorium PubMed
Finethy R., Jorgensen I., Haldar A.K., de Zoete M.R., Strowig T., Flavell R.A., Yamamoto M., Nagarajan U.M., ... , Miao E.A., Coers J. (2015)
Guanylate Binding Proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages
Infect.Immun., 83
DOI: 10.1128/IAI.00856-15 HZI-Repositorium PubMed
Wynosky-Dolfi M.A., Snyder A.G., Philip N.H., Doonan P.J., Poffenberger M.C., Avizonis D., Zwack E.E., Riblett A.M., Hu B., Strowig Till, Flavell R.A., Jones R.G., ... , Freedman B.D., Brodsky I.E. (2014)
Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome
Journal of Experimental Medicine, 211 (4)

Research group

Location