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Scoring the collective effects of SNPs: association of minor alleles with complex traits in model organisms

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Murray C.J., Ortblad K.F., Guinovart C., Lim S.S., Wolock T.M., Roberts D.A., Dansereau E.A., Graetz N., Barber R.M., Brown J.C., Wang H., Duber H.C., Naghavi M., Dicker D., Dandona L., Salomon J.A., Heuton K.R., Foreman K., Phillips D.E., Fleming T.D., Flaxman A.D., Phillips B.K., Johnson E.K., Coggeshall M.S., bd-Allah F., Abera S.F., Abraham J.P., Abubakar I., bu-Raddad L.J., bu-Rmeileh N.M., Achoki T., Adeyemo A.O., Adou A.K., Adsuar J.C., Agardh E.E., Akena D., Al Kahbouri M.J., Alasfoor D., Albittar M.I., cala-Cerra G., Alegretti M.A., Alemu Z.A., fonso-Cristancho R., Alhabib S., Ali R., Alla F., Allen P.J., Alsharif U., Alvarez E., vis-Guzman N., Amankwaa A.A., Amare A.T., Amini H., Ammar W., Anderson B.O., Antonio C.A., Anwari P., Arnlov J., Arsenijevic V.S., Artaman A., Asghar R.J., Assadi R., Atkins L.S., Badawi A., Balakrishnan K., Banerjee A., Basu S., Beardsley J., Bekele T., Bell M.L., Bernabe E., Beyene T.J., Bhala N., Bhalla A., Bhutta Z.A., Abdulhak A.B., Binagwaho A., Blore J.D., Basara B.B., Bose D., Brainin M., Breitborde N., Castaneda-Orjuela C.A., Catala-Lopez F., Chadha V.K., Chang J.C., Chiang P.P., Chuang T.W., Colomar M., Cooper L.T., Cooper C., Courville K.J., Cowie B.C., Criqui M.H., Dandona R., Dayama A., De Leo D., Degenhardt L., Del Pozo-Cruz B., Deribe K., Des Jarlais D.C., Dessalegn M., Dharmaratne S.D., Dilmen U., Ding E.L., Driscoll T.R., Durrani A.M., Ellenbogen R.G., Ermakov S.P., Esteghamati A., Faraon E.J., Farzadfar F., Fereshtehnejad S.M., Fijabi D.O., Forouzanfar M.H., Fra Paleo U., Gaffikin L., Gamkrelidze A., Gankpe F.G., Geleijnse J.M., Gessner B.D., Gibney K.B., Ginawi I.A., Glaser E.L., Gona P., Goto A., Gouda H.N., Gugnani H.C., Gupta R., Gupta R., Hafezi-Nejad N., Hamadeh R.R., Hammami M., Hankey G.J., Harb H.L., Haro J.M., Havmoeller R., Hay S.I., Hedayati M.T., Pi I.B., Hoek H.W., Hornberger J.C., Hosgood H.D., Hotez P.J., Hoy D.G., Huang J.J., Iburg K.M., Idrisov B.T., Innos K., Jacobsen K.H., Jeemon P., Jensen P.N., Jha V., Jiang G., Jonas J.B., Juel K., Kan H., Kankindi I., Karam N.E., Karch A., Karema C.K., Kaul A., Kawakami N., Kazi D.S., Kemp A.H., Kengne A.P., Keren A., Kereselidze M., Khader Y.S., Khalifa S.E., Khan E.A., Khang Y.H., Khonelidze I., Kinfu Y., Kinge J.M., Knibbs L., Kokubo Y., Kosen S., Defo B.K., Kulkarni V.S., Kulkarni C., Kumar K., Kumar R.B., Kumar G.A., Kwan G.F., Lai T., Balaji A.L., Lam H., Lan Q., Lansingh V.C., Larson H.J., Larsson A., Lee J.T., Leigh J., Leinsalu M., Leung R., Li Y., Li Y., De Lima G.M., Lin H.H., Lipshultz S.E., Liu S., Liu Y., Lloyd B.K., Lotufo P.A., Machado V.M., Maclachlan J.H., Magis-Rodriguez C., Majdan M., Mapoma C.C., Marcenes W., Marzan M.B., Masci J.R., Mashal M.T., Mason-Jones A.J., Mayosi B.M., Mazorodze T.T., Mckay A.C., Meaney P.A., Mehndiratta M.M., Mejia-Rodriguez F., Melaku Y.A., Memish Z.A., Mendoza W., Miller T.R., Mills E.J., Mohammad K.A., Mokdad A.H., Mola G.L., Monasta L., Montico M., Moore A.R., Mori R., Moturi W.N., Mukaigawara M., Murthy K.S., Naheed A., Naidoo K.S., Naldi L., Nangia V., Narayan K.M., Nash D., Nejjari C., Nelson R.G., Neupane S.P., Newton C.R., Ng M., Nisar M.I., Nolte S., Norheim O.F., Nowaseb V., Nyakarahuka L., Oh I.H., ... , Ohkubo T., Olusanya B.O. (2014)

Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Lancet, 384 (9947)

DOI: 10.1016/S0140-6736(14)60844-8 HZI-Repositorium PubMed

Zou C.J., Zhu L.J., Li Y.H., Mo Y.Q., Zheng D.H., Ma J.D., Ou-Yang X., ... , Pessler Frank, Dai L. (2013)

The association between hepatitis B virus infection and disease activity, synovitis, or joint destruction in rheumatoid arthritis

Clinical Rheumatology, 32 (6)

Li Y., Luxenburger E., Müller Rolf (2013)

An Alternative Isovaleryl CoA Biosynthetic Pathway Involving a Previously Unknown 3-Methylglutaconyl CoA Decarboxylase

Angewandte Chemie International Edition, 52 (4)

Katsuyama Y., Harmrolfs K., Pistorius D., Li Y., Müller Rolf (2012)

A Semipinacol Rearrangement Directed by an Enzymatic System Featuring Dual-Function FAD-Dependent Monooxygenase

Angewandte Chemie International Edition, 51 (37)

Pistorius D., Li Y., Sandmann A., Müller Rolf* (2011)

Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15

Molecular BioSytems, 7 (12)

Pistorius D., Li Y., Mann S., Müller Rolf* (2011)

Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis

Journal of the American Chemical Society, 133 (32)

Kukita A., Kukita T., Nagata K., Teramachi J., Li Y.J., Yoshida H., Miyamoto H., Gay S., ... , Pessler Frank*, Shobuike T. (2011)

The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo

Arthritis and Rheumatism, 63 (9)

DOI: 10.1002/art.30455 HZI-Repositorium PubMed

Li Y., Weissman K.J., Müller Rolf* (2010)

Insights into multienzyme docking in hybrid PKS-NRPS megasynthetases revealed by heterologous expression and genetic engineering

ChemBioChem, 11 (8)

Tzeneva V.A., Li Y., Felske A.D., de Vos W.M., Akkermans A.D., ... , Vaughan E.E., Smidt H. (2004)

Development and application of a selective PCR-denaturing gradient gel electrophoresis approach to detect a recently cultivated Bacillus

Applied and Environmental Microbiology, 70 (10)

Wagner-Döbler I., von Canstein H.F., Li Y., Leonhäuser J., Deckwer W.-D. (2003)

Process-integrated microbial mercury removal from wastewater of chlor-alkali electrolysis plants

Engineering in Life Sciences, 3 (4)

von Canstein H.F., Li Y., Leonhäuser J., Deckwer W.-D., Wagner-Döbler I. (2003)

Mikrobielle Reinigung von quecksilberhaltigen Industrieabwässern

Biospektrum, (2/3)

von Canstein H.F., Li Y., Leonhäuser J., Deckwer W.-D., Wagner-Döbler I. (2003)

Bioremediation of mercury-polluted industrial wastewater by mercury-reducing biofilms

Recent Research Developments in Biotechnology and Bioengineering, 5

Wagner-Döbler I., Von Canstein H., Li Y., Leonhäuser J., Deckwer W.D. (2002)

Process-integrated removal of mercury from chlor-alkali electrolysis by microorganisms

Chemie Ingenieur Technik, 74 (4)

Wagner-Döbler I., Von Canstein H., Leonhäuser J., Li Y., Deckwer W-D. (2002)

Prozessintegrierte Quecksilberentfernung aus Abwässern der Chloralkali-Elektrolyse durch Mikroorganismen.

Chemie Ingenieur Technik, 74

Von Canstein H., Kelly S., Li Y., Wagner-Döbler I. (2002)

Species diversity improves the efficiency of mercury-reducing biofilms under changing environmental conditions

Applied and Environmental Microbiology, 68 (6)

Von Canstein H., Li Y., Leonhauser J., Haase E., Felske A., ... , Deckwer W.D., Wagner-Döbler I. (2002)

Spatially oscillating activity and microbial succession of mercury-reducing biofilms in a technical-scale bioremediation system

Applied and Environmental Microbiology, 68 (4)

von Canstein H.F., Li Y., Wagner-Döbler I. (2001)

Long-term stability of mercury-reducing microbial biofilm communities analyzed by 16s-23s rDNA interspacer region polymorphism

Microbial Ecology, 42 (4)

Von Canstein H., Li Y., Wagner-Döbler I. (2001)

Long-term performance of bioreactors cleaning mercury- contaminated wastewater and their response to temperature and mercury stress and mechanical perturbation

Biotechnology and Bioengineering, 74 (3)

Felske A., Pauling B.V., von Canstein H.F., Li Y., Lauber J., ... , Buer J., Wagner-Döbler I. (2001)

Detection of small sequence differences using competitive PCR: molecular monitoring of genetically improved, mercury-reducing bacteria

Biotechniques, 30 (1)

Wagner-Döbler I., Von Canstein H., Li Y., Felske A., Pauling B. (2000)

Mercury remediation - a new solution to an old problem- Remediation of hazardous waste - environmental protection technologies

Wagner-Döbler I., Von Canstein H., Lünsdorf H., Li Y., Felske A., Pauling B. (2000)

Bioremediation of electrolysis wastewater by mercury resistant Pseudomonas strains

Wagner-Döbler I., Von Canstein H., Li Y. (2000)

Bioremediation of mercury contaminated wastewater

Bioworld

Wagner-Döbler I., Von Canstein H., Li Y., Timmis K.N., Deckwer W.D. (2000)

Removal of mercury from chemical wastewater by microoganisms in technical scale

Environmental Science & Technology, 34 (21)

Wagner-Döbler I., Lünsdorf H., Lubbehusen T., von Canstein H.F., Li Y. (2000)

Structure and species composition of mercury-reducing biofilms

Applied and Environmental Microbiology, 66 (10)

Ben-Asouli Y., Banai Y., Hauser H., Kaempfer R. (2000)

Recognition of 5'-terminal TAR structure in human immunodeficiency virus-1 mRNA by eukaryotic translation initiation factor 2

Nucleic Acids Research, 28 (4)

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Prof Dr Yang Li

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