Prof Dr Yang Li

Prof Dr Yang Li
Research Group Leader

Yang Li has headed the Department of Computational Biology for Individualised Medicine at the CiiM and the HZI since 2019 and was also appointed Director of the CiiM. The focus of her research is on understanding the molecular mechanisms of immune-related/infectious diseases through integration of multi-omics data.

Yang Li obtained her PhD in bioinformatics at the University of Groningen (The Netherlands) in 2010. She received the National Bioinformatics Young Investigator Award of 2011 in the Netherlands. In 2013, she received her first personal grant: an NWO-VENI grant from the Dutch Research Council, which is an innovative research program to supporting talented and outstanding young researchers in the Netherlands. Thereafter, Dr. Li became an independent researcher and started to build her own research team to further her interests in the complex genetics of human diseases using the multi-omics datasets. Later, she received other prestigious personal grants including a ZonMW-Offroad and a Hypatia grant. Besides that she is co-applicant on several large consortium grants. She has published ~70 scientific articles including publications in Cell, Nature Medicine, Nature Immunology and Cell Reports. She also served as reviewer for many journals such as Nature Ecology & Evolution, Bioinformatics, Journal of the Royal Statistical Society (UK) and Genetics.

Publications
el Mouali Y., Tawk C., Huang K.D., Amend L., Lesker T.R., Ponath F., ... , Vogel J., Strowig T. (2024)
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization
Cell Host.Microbe

Roesner L.M., Gupta M.K., Kopfnagel V., van Unen N., Kemmling Y., Heise J., Castell S., Jiang X., Riemann L., Traidl S., Lange B., Sühs K., Illig T., Strowig T., Li Y., Förster R., Huehn J., Schulz T.F., ... , Werfel T., RESIST SI Cohort Investigators (2024)
Correction to: The RESIST Senior Individuals Cohort: Design, participant characteristics and aims (GeroScience, (2024), 10.1007/s11357-024-01299-6)
GeroScience

Aksu M.D., van der Ent T., Zhang Z., Riza A.L., de Nooijer A.H., Ricano-Ponce I., Janssen N., Engel J.J., Streata I., Dijkstra H., Lemmers H., Grondman I., Koeken V.A.C.M., Antoniadou E., Antonakos N., Van De Veerdonk F.L., Li Y., Giamarellos-Bourboulis E.J., ... , Netea M.G., Ziogas A. (2024)
Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis
J.Infect., 89 (6)

Kumar S., Zoodsma M., Nguyen N., Pedroso R., Trittel S., Riese P., Botey-Bataller J., Zhou L., Alaswad A., Arshad H., Netea M.G., Xu C.J., Pessler F., Guzman C.A., ... , Graca L., Li Y. (2024)
Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population
Sci.Adv., 10 (39)

Mielniczuk S., Hoff K., Baselious F., Li Y., Haupenthal J., Kany A.M., Riedner M., Rohde H., Rox K., Hirsch A.K.H., Krimm I., ... , Sippl W., Holl R. (2024)
Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity
J.Med.Chem., 67 (19)

Essex M., Pascual-Leone B.M., Löber U., Kuhring M., Zhang B., Brüning U., Fritsche-Guenther R., Krzanowski M., Fiocca Vernengo F., Brumhard S., Röwekamp I., Bielecka A., Lesker T.R., Wyler E., Landthaler M., Mantei A., Meisel C., Caesar S., Thibeault C., Corman V.M., Marko L., Suttorp N., Strowig T., Kurth F., Sander L.E., Li Y., Kirwan J.A., ... , Forslund S.K., Opitz B. (2024)
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19
npj Biofilms and Microbiomes, 10 (1)

Roesner L.M., Gupta M.K., Kopfnagel V., van Unen N., Kemmling Y., Heise J.K., Castell S., Jiang X., Riemann L., Traidl S., Lange B., Sühs K.W., Illig T., Strowig T., Li Y., Förster R., Huehn J., Schulz T.F., ... , Werfel T., RESIST SI Cohort Investigators (2024)
The RESIST Senior Individuals Cohort: Design, participant characteristics and aims
GeroScience

Kilic G., Debisarun P.A., Alaswad A., Baltissen M.P., Lamers L.A., de Bree L.C.J., Benn C.S., Aaby P., Dijkstra H., Lemmers H., Martens J.H.A., Dominguez-Andres J., van Crevel R., Li Y., ... , Xu C.J., Netea M.G. (2024)
Seasonal variation in BCG-induced trained immunity
Vaccine

Botey-Bataller J., Vrijmoeth H.D., Ursinus J., Kullberg B.J., van den Wijngaard C.C., ter Hofstede H., Alaswad A., Gupta M.K., Roesner L.M., Huehn J., Werfel T., Schulz T.F., Xu C.J., Netea M.G., Hovius J.W., ... , Joosten L.A.B., Li Y. (2024)
A comprehensive genetic map of cytokine responses in Lyme borreliosis
Nature Communications, 15 (1)

Röring R.J., Li W., Liu R., Bruno M., Zhang B., Debisarun P.A., Gaal O., Badii M., Klück V., Moorlag S.J.C.F., Van De Veerdonk F., Li Y., ... , Joosten L.A.B., Netea M.G. (2024)
Epigenetic, transcriptional, and functional characterization of myeloid cells in familial Mediterranean fever
iScience, 27 (4)

Vrijmoeth H.D., Ursinus J., Botey-Bataller J., Kuijpers Y., Chu X., van de Schoor F.R., Scicluna B.P., Xu C.J., Netea M.G., Kullberg B.J., van den Wijngaard C.C., Li Y., ... , Hovius J.W., Joosten L.A.B. (2024)
Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications
BMC Infect.Dis., 24 (1)

Badii M., Klück V., Gaal O., Cabau G., Hotea I., Nica V., Mirea A.M., Bojan A., Zdrenghea M., Novakovic B., Merriman T.R., Liu Z., Li Y., Xu C.J., Pamfil C., Rednic S., Popp R.A., ... , Crisan T.O., Joosten L.A.B. (2024)
Regulation of SOCS3-STAT3 in urate-induced cytokine production in human myeloid cells
Joint Bone Spine, 91 (3)

Costa B., Becker J., Krammer T., Mulenge F., Duran V., Pavlou A., Gern O.L., Chu X., Li Y., Cicin-Sain L., Eiz-Vesper B., Messerle M., Dölken L., Saliba A.E., ... , Erhard F., Kalinke U. (2024)
Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells
Nat.Commun., 15 (1)

Almasi E.D.H., Knischewski N., Osbelt L., Muthukumarasamy U., el Mouali Y., Vialetto E., ... , Beisel C.L., Strowig T. (2024)
An adapted method for Cas9-mediated editing reveals the species-specific role of b
J.Bacteriol.

Bulut O., Temba G.S., Koeken V.A.C.M., Moorlag S.J.C.F., de Bree L.C.J., Mourits V.P., Kullaya V.I., Jaeger M., Qi C., Riksen N.P., Dominguez-Andres J., Xu C.J., Joosten L.A.B., Li Y., ... , de Mast Q., Netea M.G. (2024)
Common and distinct metabolomic markers related to immune aging in Western European and East African populations
Mech.Ageing Dev.

Frenz-Wiessner S., Fairley S.D., Buser M., Goek I., Salewskij K., Jonsson G., Illig D., Zu Putlitz B., Petersheim D., Li Y., Chen P.H., Kalauz M., Conca R., Sterr M., Geuder J., Mizoguchi Y., Megens R.T.A., Linder M.I., Kotlarz D., Rudelius M., Penninger J.M., ... , Marr C., Klein C. (2024)
Generation of complex bone marrow organoids from human induced pluripotent stem cells
Nat.Methods

Röring R.J., Debisarun P.A., Botey-Bataller J., Suen T.K., Bulut O., Kilic G., Koeken V.A., Sarlea A., Bahrar H., Dijkstra H., Lemmers H., Gössling K.L., Rüchel N., Ostermann P.N., Müller L., Schaal H., Adams O., Borkhardt A., Ariyurek Y., de Meijer E.J., Kloet S.L., ten Oever J., Placek K., ... , Li Y., Netea M.G. (2024)
MMR vaccination induces trained immunity via functional and metabolic reprogramming of g[gamma]d[delta] T cells
J.Clin.Invest

Baquero F., Beis K., Craik D.J., Li Y., Link A.J., Rebuffat S., Salom+¦n R., Severinov K., ... , Zirah S., Hegemann J.D. (2024)
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide
Natural Product Reports

Moorlag S.J.C.F., Folkman L., Ter Horst R., Krausgruber T., Barreca D., Schuster L.C., Fife V., Matzaraki V., Li W., Reichl S., Mourits V.P., Koeken V.A.C.M., Bree L.C.J., Dijkstra H., Lemmers H., van Cranenbroek B., van Rijssen E., Koenen H.J.P.M., Joosten I., Xu C.J., Li Y., Joosten L.A.B., van Crevel R., ... , Netea M.G., Bock C. (2024)
Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity
Immunity, 57 (1)

Peng C., Jiang X., Jaeger M., van Houten P., van Herwaarden A.E., Koeken V.A.C.M., Moorlag S.J.C.F., Mourits V.P., Lemmers H., Dijkstra H., Koenen H.J.P.M., Joosten I., van Cranenbroek B., Li Y., Joosten L.A.B., Netea M.G., ... , Netea-Maier R.T., Xu C.J. (2023)
11-deoxycortisol positively correlates with T cell immune traits in physiological conditions
EBioMedicine, 99

van Meijgaarden K.E., Li W., Moorlag S.J.C.F., Koeken V.A.C.M., Koenen H.J.P.M., Joosten L.A.B., Vyakarnam A., Ahmed A., Rakshit S., Adiga V., Ottenhoff T.H.M., Li Y., ... , Netea M.G., Joosten S.A. (2024)
BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination
Nature Communications, 15 (1)

Suen T.K., Moorlag S.J.C.F., Li W., de Bree C.L.J., Koeken V.A.C.M., Mourits V.P., Dijkstra H., Lemmers H., Bhat J., Xu C.J., Joosten L.A.B., Schultze J.L., Li Y., ... , Placek K., Netea M.G. (2023)
BCG vaccination induces innate immune memory in gamma delta T cells in humans
J.Leukoc.Biol.

Föhse K., Geckin B., Zoodsma M., Kilic G., Liu Z., Röring R.J., Overheul G.J., van de Maat J., Bulut O., Hoogerwerf J.J., ten Oever J., Simonetti E., Schaal H., Adams O., Müller L., Ostermann P.N., Van De Veerdonk F.L., Joosten L.A.B., Haagmans B.L., van Crevel R., van Rij R.P., GeurtsvanKessel C., de Jonge M.I., Li Y., ... , Dominguez-Andres J., Netea M.G. (2023)
The impact of BNT162b2 mRNA vaccine on adaptive and innate immune responses
Clin.Immunol., 255

Macauda A., Briem K., Clay-Gilmour A., Cozen W., Försti A., Giaccherini M., Corradi C., Sainz J., Niazi Y., Ter Horst R., Li Y., Netea M.G., Vogel U., Hemminki K., Slager S.L., Varkonyi J., Andersen V., Iskierka-Jazdzewska E., Martinez-Lopez J., Zaucha J., Camp N.J., Rajkumar S.V., Druzd-Sitek A., Bhatti P., Chanock S.J., Kumar S.K., Subocz E., Mazur G., Landi S., Machiela M.J., Jerez A., Norman A.D., Hildebrandt M.A.T., Kadar K., Berndt S.I., Ziv E., Buda G., Nagler A., Dumontet C., Razny M., Watek M., Butrym A., Grzasko N., Dudzinski M., Rybicka-Ramos M., Matera E.L., Garcia-Sanz R., Goldschmidt H., Jamroziak K., Jurczyszyn A., Clavero E., Giles G.G., Pelosini M., Zawirska D., Kruszewski M., Marques H., Haastrup E., Sanchez-Maldonado J.M., Bertsch U., Rymko M., Raab M.S., Brown E.E., Hofmann J.N., Vachon C., ... , Campa D., Canzian F. (2023)
Identification of novel genetic loci for risk of multiple myeloma by functional annotation
Leukemia

Gupta M.K., Peng H., Li Y., Xu C.J. (2023)
The role of DNA methylation in personalized medicine for immune-related diseases
Pharmacol.Ther., 250

Fries A., Saidoune F., Kuonen F., Dupanloup I., Fournier N., Guerra de Souza A.C., Haniffa M., Ma F., Gudjonsson J.E., Roesner L., Li Y., Werfel T., Conrad C., Gottardo R., Modlin R.L., ... , Di Domizio J., Gilliet M. (2023)
Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis
Nat.Commun., 14 (1)

Mol J.Q., van Tuijl J., Bekkering S., van der Heijden C.D.C.C., Damen S.A.J., Cossins B.C., van Emst L., Nielen T.M., Rodwell L., Li Y., Pop G.A.M., Netea M.G., van Royen N., ... , Riksen N.P., El Messaoudi S. (2023)
Peripheral blood mononuclear cell hyperresponsiveness in patients with premature myocardial infarction without traditional risk factors
iScience, 26 (7)

Clavero E., Sanchez-Maldonado J.M., Macauda A., Ter Horst R., Sampaio-marques B., Jurczyszyn A., Clay-Gilmour A., Stein A., Hildebrandt M.A.T., Weinhold N., Buda G., Garcia-Sanz R., Tomczak W., Vogel U., Jerez A., Zawirska D., Watek M., Hofmann J.N., Landi S., Spinelli J.J., Butrym A., Kumar A., Martinez-Lopez J., Galimberti S., Sarasquete M.E., Subocz E., Iskierka-Jazdzewska E., Giles G.G., Rybicka-Ramos M., Kruszewski M., Abildgaard N., Verdejo F.G., Sanchez Rovira P., Da Silva Filho M.I., Kadar K., Razny M., Cozen W., Pelosini M., Jurado M., Bhatti P., Dudzinski M., Druzd-Sitek A., Orciuolo E., Li Y., Norman A.D., Zaucha J.M., Reis R.M., Markiewicz M., Rodriguez Sevilla J.J., Andersen V., Jamroziak K., Hemminki K., Berndt S.I., Rajkumar V., Mazur G., Kumar S.K., Ludovico P., Nagler A., Chanock S.J., Dumontet C., Machiela M.J., Varkonyi J., Camp N.J., Ziv E., Vangsted A.J., Brown E.E., Campa D., Vachon C.M., Netea M.G., Canzian F., ... , Fösti A., Sainz J. (2023)
Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization
Int.J Mol.Sci., 24 (10)

Cabrera-Serrano A.J., Sanchez-Maldonado J.M., Ter Horst R., Macauda A., Garcia-Martin P., Benavente Y., Landi S., Clay-Gilmour A., Niazi Y., Espinet B., Rodriguez-Sevilla J.J., Perez E.M., Maffei R., Blanco G., Giaccherini M., Cerhan J.R., Marasca R., Lopez-Nevot M.A., Chen-Liang T., Thomsen H., Gamez I., Campa D., Moreno V., de Sanjose S., Marcos-Gragera R., Garcia-Alvarez M., Dierssen-Sotos T., Jerez A., Butrym A., Norman A.D., Luppi M., Slager S.L., Hemminki K., Li Y., Berndt S.I., Casabonne D., Alcoceba M., Puiggros A., Netea M.G., Försti A., ... , Canzian F., Sainz J. (2023)
Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?
Int.J.Mol.Sci., 24 (9)

Li W., Moorlag S.J.C.F., Koeken V.A.C.M., R+Âring R.J., de Bree L.C.J., Mourits V.P., Gupta M.K., Zhang B., Fu J., Zhang Z., Grondman I., van Meijgaarden K.E., Zhou L., Alaswad A., Joosten L.A.B., van Crevel R., Xu C.J., ... , Netea M.G., Li Y. (2023)
A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity
Cell Rep., 42 (5)

Cossins B.C., van den Munckhof I., Rutten J.H.W., van der Graaf M., Stienstra R., Joosten L.A.B., Netea M.G., ... , Li Y., Riksen N.P. (2023)
Sex-specific association between adipose tissue inflammation and vascular and metabolic complications of obesity
J.Clin.Endocrinol.Metab

Blaauw M.J.T., Cristina dos Santos J., Vadaq N., Trypsteen W., van der Heijden W., Groenendijk A., Zhang Z., Li Y., Mast Q., Netea M.G., Joosten L.A.B., Vandekerckhove L., ... , van der Ven A., Matzaraki V. (2023)
Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size
iScience, 26 (4)

Sanchez-Maldonado J.M., Cabrera-Serrano A.J., Chattopadhyay S., Campa D., Garrido M.D.P., Macauda A., Ter Horst R., Jerez A., Netea M.G., Li Y., Hemminki K., Canzian F., ... , Försti A., Sainz J. (2023)
GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis
International Journal of Molecular Sciences, 24 (7)

Fu J., Zhu F., Xu C.J., Li Y. (2023)
Metabolomics meets systems immunology
EMBO Rep.

Geckin B., Zoodsma M., Kilic G., Debisarun P.A., Rakshit S., Adiga V., Ahmed A., Parthiban C., Kumar N.C., D'Souza G., Baltissen M.P., Martens J.H.A., Dominguez-Andres J, Li Y, ... , Vyakarnam A, Netea M.G (2023)
Differences in Immune Responses in Individuals of Indian and European Origin: Relevance for the COVID-19 Pandemic
Microbiol.Spectr.

Zhang B., Zhang Z., Koeken V.A.C.M., Kumar S., Aillaud M., Tsay H.C., Liu Z., Kraft A.R.M., Soon C.F., Odak I., Bosnjak B., Vlot A., Swertz M.A., Ohler U., Geffers R., Illig T., Hühn J., Saliba A.E., Sander L.E., Förster R., Xu C.J., Cornberg M., Schulte L.N., ... , Li Y., Deutsche C.O.V.I. (2023)
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19
Cell Genom.

van Breugel M., Qi C., Xu Z., Pedersen C.E.T., Petoukhov I., Vonk J.M., Gehring U., Berg M., Bügel M., Carpaij O.A., Forno E., Morin A., Eliasen A.U., Jiang Y., van den Berge M., Nawijn M.C., Li Y., Chen W., Bont L.J., Bonnelykke K., Celedon J.C., ... , Koppelman G.H., Xu C.J. (2022)
Nasal DNA methylation at three CpG sites predicts childhood allergic disease
Nat.Commun., 13 (1)

Kirchner T., Heinrich S., Bonifacius A., Engel B., Ruhl L., Pink I., Thomas N., Martens J., Hoeper M.M., Blasczyk R., Wedemeyer H., Jaeckel E., Li Y., Falk C.S., ... , Eiz-Vesper B., Taubert R. (2022)
Reduced humoral but stable cellular SARSCoV-2-specific immunity in liver transplant recipients in the first year after COVID-19
PLoS ONE, 17 (11 November)

Zoodsma M., de Nooijer A.H., Grondman I., Gupta M.K., Bonifacius A., Koeken V.A.C.M., Kooistra E., Kilic G., Bulut O., Gödecke N., Janssen N., Kox M., Domínguez-Andrés J., van Gammeren A.J., Ermens A.A.M., van der Ven A.J.A.M., Pickkers P., Blasczyk R., Behrens G.M.N., Van De Veerdonk F.L., Joosten L.A.B., Xu C.J., Eiz-Vesper B., ... , Netea M.G., Li Y. (2022)
Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19
Front.Immunol., 13

Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A. (2022)
Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly
Nat.Commun., 13 (1)

Rakshit S., Adiga V., Ahmed A., Parthiban C., Chetan Kumar N., Dwarkanath P., Shivalingaiah S., Rao S., D'Souza G., Dias M., Maguire T.J.A., Doores K.J., Zoodsma M., Geckin B., Dasgupta P., Babji S., van Meijgaarden K.E., Joosten S.A., Ottenhoff T.H.M., Li Y., Netea M.G., Stuart K.D., De Rosa S.C., ... , McElrath M.J., Vyakarnam A. (2022)
Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults
Front.Immunol., 13

Rabold K., Zoodsma M., Grondman I., Kuijpers Y., Bremmers M., Jaeger M., Zhang B., Hobo W., Bonenkamp H.J., de Wilt J.H.W., Janssen M.J.R., Cornelissen L.A.M., van Engen-van Grunsven I.C.H., Mulder W.J.M., Smit J.W.A., Adema G.J., Netea M.G., Li Y., ... , Xu C.J., Netea-Maier R.T. (2022)
Reprogramming of myeloid cells and their progenitors in patients with non-medullary thyroid carcinoma
Nat.Commun., 13 (1)

Ouyang L., Chen B., Liu X., Wang D., Li Y., Liao Y., ... , Yeung K.W.K., Liu X. (2023)
Puerarin@Chitosan composite for infected bone repair through mimicking the bio-functions of antimicrobial peptides
Bioact.Mater., 21

Bruno M., Horst R., Pekmezovic M., Kumar V., Li Y., Netea M.G., Latgé J.P., ... , Gresnigt M.S., Van De Veerdonk F.L. (2021)
Data of common and species-specific transcriptional host responses to pathogenic fungi
Data Brief, 35

Yang J., Zou M., Chu X., Floess S., Li Y., ... , Delacher M., Hühn J. (2022)
Inflammatory perturbations in early life long-lastingly shape the transcriptome and TCR repertoire of the first wave of regulatory T cells
Front.Immunol., 13

Koeken V.A.C.M., Qi C., Mourits V.P., de Bree L.C.J., Moorlag S.J.C.F., Sonawane V., Lemmers H., Dijkstra H., Joosten L.A.B., van Laarhoven A., Xu C.J., van Crevel R., ... , Netea M.G., Li Y. (2022)
Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination
PLoS Biol., 20 (9)

Plenderleith L.J., Liu W., Li Y., Loy D.E., Mollison E., Connell J., Ayouba A., Esteban A., Peeters M., Sanz C.M., Morgan D.B., Wolfe N.D., Ulrich M., Sachse A., Calvignac-Spencer S., Leendertz F.H., Shaw G.M., ... , Hahn B.H., Sharp P.M. (2022)
Zoonotic origin of the human malaria parasite Plasmodium malariae from African apes
Nat.Commun., 13 (1)

Melaiu O., Macauda A., Sainz J., Calvetti D., Facioni M.S., Maccari G., Ter Horst R., Netea M.G., Li Y., Grzasco N., Moreno V., Jurczyszyn A., Jerez A., Watek M., Varkonyi J., Garcia-Sanz R., Kruszewski M., Dudzínski M., Kadar K., Jacobsen S.E.H., Mazur G., Andersen V., Rybicka M., Zawirska D., Razny M., Zaucha J.M., Ostrovsky O., Iskierka-Jazdzewska E., Reis R.M., Stepien A., Beider K., Nagler A., Druzd-Sitek A., Marques H., Martínez-Lopez J., Lesueur F., vet-Loiseau H., Vangsted A.J., Krawczyk-Kulis M., Butrym A., Jamroziak K., Dumontet C., Vogel U., Rymko M., Pelosini M., Subocz E., Szombath G., Sarasquete M.E., Silvestri R., Morani F., Landi S., Campa D., ... , Canzian F., Gemignani F. (2021)
Common gene variants within 3'-untranslated regions as modulators of multiple myeloma risk and survival
International Journal of Cancer, 148 (8)

Matzaraki V., Le K.T.T., Jaeger M., Aguirre-Gamboa R., Johnson M.D., Sanna S., Rosati D., Franke L., Zhernakova A., Fu J., Withoff S., Jonkers I., Li Y., Joosten L.A.B., Netea M.G., ... , Wijmenga C., Kumar V. (2021)
Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability
Frontiers in Immunology, 12

Jaeger M., Sloot Y.J.E., Horst R.T., Chu X., Koenen H.J.P.M., Koeken V.A.C.M., Moorlag S.J.C.F., Bree C.J., Mourits V.P., Lemmers H., Dijkstra H., Medici M., van Herwaarden A.E., Joosten I., Joosten L.A.B., Li Y., Smit J.W.A., ... , Netea M.G., Netea-Maier R.T. (2021)
Thyrotrophin and thyroxine support immune homeostasis in humans
Immunology, 163 (2)

Bakker O.B., Ramirez-Sánchez A.D., Borek Z.A., Klein N., Li Y., Modderman R., Kooy-Winkelaar Y., Johannesen M.K., Matarese F., Martens J.H.A., Kumar V., van Bergen J., Qiao S.W., Lundin K.E.A., Sollid L.M., Koning F., Wijmenga C., ... , Withoff S., Jonkers I.H. (2021)
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Scientific Reports, 11 (1)

van Eekeren L.E., Matzaraki V., Zhang Z., van de Wijer L., Blaauw M.J.T., de Jonge M.I., Vandekerckhove L., Trypsteen W., Joosten L.A.B., Netea M.G., de Mast Q., Koenen H.J.P.M., ... , Li Y., van der Ven A.J.A.M. (2022)
People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells
Sci.Rep., 12 (1)

Aznaourova M., Schmerer N., Janga H., Zhang Z., Pauck K., Bushe J., Volkers S.M., Wendisch D., Georg P., Ntini E., Aillaud M., Gündisch M., Mack E., Skevaki C., Keller C., Bauer C., Bertrams W., Marsico A., Nist A., Stiewe T., Gruber A.D., Ruppert C., Li Y., Garn H., Sander L.E., ... , Schmeck B., Schulte L.N. (2022)
Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19
Proc.Natl.Acad.Sci.U.S.A, 119 (36)

Zhang B., Roesner L.M., Traidl S., Koeken V.A.C.M., Xu C.J., ... , Werfel T., Li Y. (2022)
Single-cell profiles reveal distinctive immune response in atopic dermatitis in contrast to psoriasis
Allergy

Kerstholt M., van de Schoor F.R., Oosting M., Moorlag S.J.C.F., Li Y., Jaeger M., van der Heijden W.A., Tunjungputri R.N., dos Santos J.C., Vrijmoeth H.D., Baarsma M.E., Kullberg B.J., Lupse M., Hovius J.W., van den Wijngaard C.C., Netea M.G., ... , deMast Q., Joosten L.A.B. (2022)
Identifying platelet-derived factors as amplifiers of B. burgdorferi-induced cytokine production
Clin.Exp.Immunol.

Chu X., Janssen A.W.M., Koenen H., Chang L., He X., Joosten I., Stienstra R., Kuijpers Y., Wijmenga C., Xu C.J., Netea M.G., ... , Tack C.J., Li Y. (2022)
A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes
Elife., 11

Burgers L.D., Li Y., Michalakis S., Ciurus S., Zahler S., ... , Müller R., Fürst R. (2022)
The protein biosynthesis inhibitor vioprolide A evokes anti-angiogenic and pro-survival actions by targeting NOP14 and decreasing VEGF receptor 2- and TAZ-signaling
Biomed.Pharmacother., 152

Qi C., Berg M., Chu X., Timens W., Kole T., van den Berge M., Xu C.J., Koppelman G.H., ... , Nawijn M.C., Li Y. (2022)
Cell-type eQTL deconvolution of bronchial epithelium through integration of single-cell and bulk RNA-seq
Allergy

Kuijpers Y., Chu X., Jaeger M., Moorlag S.J.C.F., Koeken V.A.C.M., Zhang B., de Nooijer A., Grondman I., Gupta M.K., Janssen N., Mourits V.P., de Bree L.C.J., de Mast Q., van de V, Joosten L.A.B., Li Y., ... , Netea M.G., Xu C.J. (2022)
The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses
Front Immunol., 13

Sánchez-Maldonado J.M., Collado R., Cabrera-Serrano A.J., Horst R.T., Gálvez-Montosa F., Robles-Fernández I., Arenas-Rodríguez V., Cano-Gutíerrez B., Bakker O., Bravo-Fernández M.I., García-verdejo F.J., López J.A.L., Olivares-Ruiz J., López-Nevot M.À, Fernández-Puerta L., Cózar-Olmo J.M., Li Y., Netea M.G., Jurado M., Lorente J.A., Sánchez-rovira P., ... , Àlvarez-Cubero M.J., Sainz J. (2022)
Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis
Cancers, 14 (10)

Ramírez-Sánchez A.D., Chu X., Modderman R., Kooy-Winkelaar Y., Koletzko S., Korponay-Szabó I.R., Troncone R., Wijmenga C., Mearin L., Withoff S., ... , Jonkers I.H., Li Y. (2022)
Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Pediatric Coeliac Disease Patients Suggests Potential Pre-Seroconversion Markers
Frontiers in Immunology, 13

Kuijpers Y., Domínguez-Andrés J., Bakker O.B., Gupta M.K., Grasshoff M., Xu C.J., Joosten L.A.B., Bertranpetit J., ... , Netea M.G., Li Y. (2022)
Evolutionary Trajectories of Complex Traits in European Populations of Modern Humans
Frontiers in Genetics, 13

Liu Z., Kilic G., Li W., Bulut O., Gupta M.K., Zhang B., Qi C., Peng H., Tsay H.C., Soon C.F., Mekonnen Y.A., Ferreira A.V., van der Made C.I., van Cranenbroek B., Koenen H.J.P.M., Simonetti E., Diavatopoulos D., de Jonge M.I., Müller L., Schaal H., Ostermann P.N., Cornberg M., Eiz-Vesper B., Van De Veerdonk F., van Crevel R., Joosten L.A.B., Dominguez-Andres J., Xu C.J., ... , Netea M.G., Li Y. (2022)
Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19
Front Immunol., 13

Zhang B., Moorlag S.J., Domínguez-Andrés J., Bulut Ö, Kilic G., Liu Z., van Crevel R., Xu C.J., Joosten L.A., ... , Netea M.G., Li Y. (2022)
Single-cell RNA sequencing reveals induction of distinct trained immunity programs in human monocytes
J.Clin.Invest, 132 (7)

Matera G., Altuvia Y., Gerovac M., el Mouali Y., Margalit H., Vogel J. (2022)
Global RNA interactome of Salmonella discovers a 5' UTR sponge for the MicF small RNA that connects membrane permeability to transport capacity
Mol.Cell, 82 (3)

Tan I.L., Coutinho de Almeida R., Modderman R., Stachurska A., Dekens J., Barisani D., Meijer C.R., Roca M., Martinez-Ojinaga E., Shamir R., Auricchio R., Korponay-Szabó I.R., Castillejo G., Szajewska H., Koletzko S., Zhernakova A., Kumar V., Li Y., Visschedijk M.C., Weersma R.K., Troncone R., Mearin M.L., Wijmenga C., ... , Jonkers I., Withoff S. (2021)
Circulating miRNAs as Potential Biomarkers for Celiac Disease Development
Front.Immunol., 12

Sanchez-Maldonado J.M., Cáliz R., López-Nevot M.À, Cabrera-Serrano A.J., Moniz-Díez A., Canhao H., Ter Horst R., Quartuccio L., Sorensen S.B., Glintborg B., Hetland M., Filipescu I., Pérez-Pampin E., Conesa-Zamora P., Swierkot J., den Broeder A.A., De Vita S., Petersen E.R.B., Li Y., Ferrer M.A., Escudero A., Netea M., Coenen M.J.H., Andersen V., Fonseca J.E., Jurado M., Bogunia-Kubik K., ... , Collantes E., Sainz J. (2021)
Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts
Front.Immunol., 12

Zhang Z., Trypsteen W., Blaauw M., Chu X., Rutsaert S., Vandekerckhove L., van der Heijden W., dos Santos J.C., Xu C.J., Swertz M.A., ... , van der Ven A., Li Y. (2021)
IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis
BMC Med., 19 (1)

Moorlag S.J.C.F., Matzaraki V., van Puffelen J.H., van der Heijden C., Keating S., Groh L., Röring R.J., Bakker O.B., Koeken V.A.C.M., de Bree L.C.J., Smeekens S.P., Oosting M., Gamboa R.A., Riksen N.P., Xavier R.J., Wijmenga C., Kumar V., van Crevel R., Novakovic B., Joosten L.A.B., ... , Li Y., Netea M.G. (2021)
An integrative genomics approach identifies KDM4 as a modulator of trained immunity
Eur.J.Immunol.

Yinka-Ogunleye A., Aruna O., Dalhat M., Ogoina D., McCollum A., Disu Y., Mamadu I., Akinpelu A., Ahmad A., Burga J., Ndoreraho A., Nkunzimana E., Manneh L., Mohammed A., Adeoye O., Tom-Aba D., Silenou B., Ipadeola O., Saleh M., Adeyemo A., Nwadiutor I., Aworabhi N., Uke P., John D., Wakama P., Reynolds M., Mauldin M.R., Doty J., Wilkins K., Musa J., Khalakdina A., Adedeji A., Mba N., Ojo O., Krause G., Ihekweazu C., Mandra A., Davidson W., Olson V., Li Y., Radford K., Zhao H., Townsend M., Burgado J., ... , Satheshkumar P.S., CDC Monkeypox Outbreak Team (2019)
Outbreak of human monkeypox in Nigeria in 2017-18: a clinical and epidemiological report
Lancet Infect.Dis., 19 (8)

Aliabadi E., Urbanek-Quaing M., Maasoumy B., Bremer B., Grasshoff M., Li Y., Niehaus C.E., Wedemeyer H., ... , Kraft A.R.M., Cornberg M. (2021)
Impact of HBsAg and HBcrAg levels on phenotype and function of HBV-specific T cells in patients with chronic hepatitis B virus infection
GUT

Debisarun P.A., Gössling K.L., Bulut O., Kilic G., Zoodsma M., Liu Z., Oldenburg M., Rüchel N., Zhang B., Xu C.J., Struycken P., Koeken V.A.C.M., Domínguez-Andrés J., Moorlag S.J.C.F., Taks E., Ostermann P.N., Müller L., Schaal H., Adams O., Borkhardt A., Oever J., van Crevel R., ... , Li Y., Netea M.G. (2021)
Induction of trained immunity by influenza vaccination - Impact on COVID-19
PLoS Pathogens, 17 (10)

Burgers L.D., Luong B., Li Y., Fabritius M.P., Michalakis S., Reichel C.A., ... , Müller R., Fürst R. (2021)
The natural product vioprolide A exerts anti-inflammatory actions through inhibition of its cellular target NOP14 and downregulation of importin-dependent NF- k
Biomed.Pharmacother., 144 (Dec. 2021)

el Mouali Y., Ponath F., Scharrer V., Wenner N., Hinton J.C., Vogel J. (2021)
Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease
RNA.

Dominguez-Andres J.., Kuijpers Y., Bakker O.B., Jaeger M, Xu C.J., Van der Meer J.W., Jakobsson M., Bertranpetit J., Joosten L.A, ... , Li Y., Netea M.G. (2021)
Evolution of cytokine production capacity in ancient and modern European populations
Elife., 10

Miethke M., Pieroni M., Weber T., Brönstrup M., Hammann P., Halby L., Arimondo P.B., Glaser P., Aigle B., Bode H.B., Moreira R., Li Y., Luzhetskyy A., Medema M.H., Pernodet J.L., Stadler M., Tormo J.R., Genilloud O., Truman A.W., Weissman K.J., Takano E., Sabatini S., Stegmann E., Brötz-Oesterhelt H., Wohlleben W., Seemann M., Empting M., Hirsch A.K.H., Loretz B., Lehr C.M., Titz A., Herrmann J., Jaeger T., Alt S., Hesterkamp T., Winterhalter M., Schiefer A., Pfarr K., Hoerauf A., Graz H., Graz M., Lindvall M., Ramurthy S., Karlen A., van Dongen M., Petkovic H., Keller A., Peyrane F., Donadio S., Fraisse L., Piddock L.J.V., Gilbert I.H., ... , Moser H.E., Müller R. (2021)
Towards the sustainable discovery and development of new antibiotics
Nat.Rev.Chem.

Chu X., Zhang B., Koeken V.A.C.M., Gupta M.K., Li Y. (2021)
Multi-Omics Approaches in Immunological Research
Frontiers in Immunology, 12

Chu X., Jaeger M., Beumer J., Bakker O.B., Aguirre-Gamboa R., Oosting M., Smeekens S.P., Moorlag S., Mourits V.P., Koeken V.A.C.M., Bree C., Jansen T., Mathews I.T., Dao K., Najhawan M., Watrous J.D., Joosten I., Sharma S., Koenen H.J.P.M., Withoff S., Jonkers I.H., Netea-Maier R.T., Xavier R.J., Franke L., Xu C.J., Joosten L.A.B., Sanna S., Jain M., Kumar V., Clevers H., Wijmenga C., ... , Netea M.G., Li Y. (2021)
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease
Genome Biology, 22 (1)

Netea M.G., Li Y. (2021)
Immune memory in individuals with COVID-19
Nat.Cell Biol., 23 (6)

Warnat-Herresthal S., Schultze H., Shastry K.L., Manamohan S., Mukherjee S., Garg V., Sarveswara R., Händler K., Pickkers P., Aziz N.A., Ktena S., Tran F., Bitzer M., Ossowski S., Casadei N., Herr C., Petersheim D., Behrends U., Kern F., Fehlmann T., Schommers P., Lehmann C., Augustin M., Rybniker J., Altmüller J., Mishra N., Bernardes J.P., Krämer B., Bonaguro L., Schulte-Schrepping J., De Domenico E., Siever C., Kraut M., Desai M., Monnet B., Saridaki M., Siegel C.M., Drews A., Nuesch-Germano M., Theis H., Heyckendorf J., Schreiber S., Kim-Hellmuth S., Balfanz P., Eggermann T., Boor P., Hausmann R., Kuhn H., Isfort S., Stingl J.C., Schmalzing G., Kuhl C.K., Röhrig R., Marx G., Uhlig S., Dahl E., Müller-Wieland D., Dreher M., Marx N., Nattermann J., Skowasch D., Kurth I., Keller A., Bals R., Nürnberg P., Rieß O., Rosenstiel P., Netea M.G., Theis F., Mukherjee S., Backes M., Aschenbrenner A.C., Ulas T., Angelov A., Bartholomäus A., Becker A., Bezdan D., Blumert C., Bonifacio E., Bork P., Boyke B., Blum H., Clavel T., Colome-Tatche M., Cornberg M., De La Rosa Velazquez I.A., Diefenbach A., Dilthey A., Fischer N., Förstner K., Franzenburg S., Frick J.S., Gabernet G., Gagneur J., Ganzenmueller T., Gauder M., Geißert J., Goesmann A., Göpel S., Grundhoff A., Grundmann H., Hain T., Hanses F., Hehr U., Heimbach A., Hoeper M., Horn F., Hübschmann D., Hummel M., Iftner T., Iftner A., Illig T., Janssen S., Kalinowski J., Kallies R., Kehr B., Keppler O.T., Klein C., Knop M., Kohlbacher O., Köhrer K., Korbel J., Kremsner P.G., Kühnert D., Landthaler M., Li Y., Ludwig K.U., Makarewicz O., Marz M., McHardy A.C., Mertes C., Münchhoff M., Nahnsen S., Nöthen M., Ntoumi F., Overmann J., Peter S., Pfeffer K., Pink I., Poetsch A.R., Protzer U., Pühler A., Rajewsky N., Ralser M., Reiche K., Ripke S., da Rocha U.N., Saliba A.E., Sander L.E., Sawitzki B., Scheithauer S., Schiffer P., Schmid-Burgk J., Schneider W., Schulte E.C., Sczyrba A., Sharaf M.L., Singh Y., Sonnabend M., Stegle O., Stoye J., Vehreschild J., Velavan T.P., Vogel J., Volland S., von Kleist M., Walker A., Walter J., Wieczorek D., Winkler S., Ziebuhr J., Breteler M.M.B., Giamarellos-Bourboulis E.J., Kox M., Becker M., Cheran S., Woodacre M.S., Goh E.L., Schultze J.L., ... , COVID-19 Aachen Study (COVAS), Deutsche COVID-19 Omics Initiative (DeCOI) (2021)
Swarm Learning for decentralized and confidential clinical machine learning
Nature, 594 (7862)

el Mouali Y., Gerovac M., Mineikaite R., Vogel J. (2021)
In vivo targets of Salmonella FinO include a FinP-like small RNA controlling copy number of a cohabitating plasmid
Nucleic Acids Res., 49 (9)

Bernardes J.P., Mishra N., Tran F., Bahmer T., Best L., Blase J.I., Bordoni D., Franzenburg J., Geisen U., Josephs-Spaulding J., Köhler P., Künstner A., Rosati E., Aschenbrenner A.C., Bacher P., Baran N., Boysen T., Brandt B., Bruse N., Dörr J., Dräger A., Elke G., Ellinghaus D., Fischer J., Forster M., Franke A., Franzenburg S., Frey N., Friedrichs A., Fuß J., Glück A., Hamm J., Hinrichsen F., Hoeppner M.P., Imm S., Junker R., Kaiser S., Kan Y.H., Knoll R., Lange C., Laue G., Lier C., Lindner M., Marinos G., Markewitz R., Nattermann J., Noth R., Pickkers P., Rabe K.F., Renz A., Röcken C., Rupp J., Schaffarzyk A., Scheffold A., Schulte-Schrepping J., Schunk D., Skowasch D., Ulas T., Wandinger K.P., Wittig M., Zimmermann J., Busch H., Hoyer B.F., Kaleta C., Heyckendorf J., Kox M., Rybniker J., Schreiber S., Schultze J.L., Rosenstiel P., Banovich N.E., Desai T., Eickelberg O., Haniffa M., Horvath P., Kropski J.A., Lafyatis R., Lundeberg J., Meyer K., Nawijn M.C., Nikolic M., Ordovas Montanes J., Pe'er D., Tata P.R., Rawlins E., Regev A., Reyfman P., Samakovlis C., Schultze J., Shalek A., Shepherd D., Spence J., Teichmann S., Theis F., Tsankov A., van den Berge M., von Papen M., Whitsett J., Zaragosi L.E., Angelov A., Bals R., Bartholomäus A., Becker A., Bezdan D., Bonifacio E., Bork P., Clavel T., Colme-Tatche M., Diefenbach A., Dilthey A., Fischer N., Förstner K., Frick J.S., Gagneur J., Goesmann A., Hain T., Hummel M., Janssen S., Kalinowski J., Kallies R., Kehr B., Keller A., Kim-Hellmuth S., Klein C., Kohlbacher O., Korbel J.O., Kurth I., Landthaler M., Li Y., Ludwig K., Makarewicz O., Marz M., McHardy A., Mertes C., Nöthen M., Nürnberg P., Ohler U., Ossowski S., Overmann J., Peter S., Pfeffer K., Poetsch A.R., Pühler A., Rajewsky N., Ralser M., Rieß O., Ripke S., Nunes da Rocha U., Saliba A.E., Sander L.E., Sawitzki B., Schiffer P., Schulte E.C., Sczyrba A., Stegle O., Stoye J., Vehreschild J., Vogel J., von Kleist M., Walker A., Walter J., Wieczorek D., Ziebuhr J., ... , HCA Lung Biological Network, the Deutsche C.O.V.I. (2020)
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19
Immunity, 53 (6)

Tan L., Fichtner A.S., Bruni E., Odak I., Sandrock I., Bubke A., Borchers A., Schultze-Florey C., Koenecke C., Förster R., Jarek M., Von Kaisenberg C., Schulz A., Chu X., Zhang B., Li Y., Panzer U., Krebs C.F., ... , Ravens S., Prinz I. (2021)
A fetal wave of human type 3 effector gamma delta cells with restricted TCR diversity persists into adulthood
Sci.Immunol., 6 (58)

Sainz J., García-verdejo F.J., Martínez-Bueno M., Kumar A., Sánchez-Maldonado J.M., Díez-villanueva A., Vodicková L., Vymetálková V., Sánchez V.M., Da Silva Filho M.I., Sampaio-marques B., Brezina S., Butterbach K., Horst R.T., Hoffmeister M., Ludovico P., Jurado M., Li Y., Sánchez-rovira P., Netea M.G., Gsur A., Vodicka P., Moreno V., Hemminki K., Brenner H., ... , Chang-Claude J., Försti A. (2021)
Polymorphisms within autophagy-related genes influence the risk of developing colorectal cancer: A meta-analysis of four large cohorts
Cancers, 13 (6)

van Leent M.M.T., Beldman T.J., Toner Y.C., Lameijer M.A., Rother N., Bekkering S., Teunissen A.J.P., Zhou X., van der Meel R., Malkus J., Nauta S.A., Klein E.D., Fay F., Sanchez-Gaytan B.L., Perez-Medina C., Kluza E., Ye Y.X., Wojtkiewicz G., Fisher E.A., Swirski F.K., Nahrendorf M., Zhang B., Li Y., Zhang B., Joosten L.A.B., Pasterkamp G., Boltjes A., Fayad Z.A., Lutgens E., Netea M.G., Riksen N.P., ... , Mulder W.J.M., Duivenvoorden R. (2021)
Prosaposin mediates inflammation in atherosclerosis
Sci.Transl.Med., 13 (584)

van der Graaf A., Zorro M.M., Claringbould A., Vosa U., Aguirre-Gamboa R., Li C., Mooiweer J., Ricano-Ponce I., Borek Z., Koning F., Kooy-Winkelaar Y., Sollid L.M., Qiao S.W., Kumar V., Li Y., Franke L., Withoff S., Wijmenga C., Sanna S., ... , Jonkers I., BIOS Consortium (2021)
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFN? Signaling in Celiac Disease
Front.Genet., 11

Li G., Zhang B., Hao J., Chu X., Wiestler M., Cornberg M., Xu C.J., ... , Liu X., Li Y. (2021)
Identification of Novel Population-Specific Cell Subsets in Chinese Ulcerative Colitis Patients Using Single-Cell RNA Sequencing
Cell Mol.Gastroenterol.Hepatol., 12 (1)

Bonifacius A., Tischer-Zimmermann S., Dragon A.C., Gussarow D., Vogel A., Krettek U., Gödecke N., Yilmaz M., Kraft A.R.M., Hoeper M.M., Pink I., Schmidt J.J., Li Y., Welte T., Maecker-Kolhoff B., Martens J., Berger M.M., Lobenwein C., Stankov M.V., Cornberg M., David S., Behrens G.M.N., Witzke O., ... , Blasczyk R., Eiz-Vesper B. (2021)
COVID-19 immune signatures reveal stable antiviral Tcell function despite declining humoral responses
Immunity., 54 (2)

Koeken V.A.C.M., van Crevel R., Netea M.G., Li Y. (2021)
Resolving trained immunity with systems biology
Eur.J.Immunol.

Bruno M., Dewi I.M.W., Matzaraki V., Ter Horst R., Pekmezovic M., Rösler B., Groh L., R÷ring R.J., Kumar V., Li Y., Carvalho A., Netea M.G., Latgé J.P., ... , Gresnigt M.S., Van De Veerdonk F.L. (2021)
Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways
Comput.Struct.Biotechnol.J., 19 (Jan 2021)

Sanchez-Maldonado J.M., Moniz-Díez A., Ter Horst R., Campa D., Cabrera-Serrano A.J., Martínez-Bueno M., Garrido-Collado M.D.P., Hernández-Mohedo F., Fernández-Puerta L., Lopez-Nevot M.Á, Cunha C., Gonzalez-Sierra P.A., Springer J., Lackner M., Acazar-Fuoli L., Fianchi L., Aguado J.M., Pagano L., Lopez-Fernández E., Clavero E., Potenza L., Luppi M., Moratalla L., Solano C., Sampedro A., Cuenca-Estrella M., Lass-Flörl C., Canzian F., Loeffler J., Li Y., Einsele H., Netea M.G., Vazquez L., Carvalho A., Jurado M., ... , Sainz J., Pcraga Study Group (2020)
Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium
J.Fungi.(Basel), 7 (1)

Xu C.J., Gruzieva O., Qi C., Esplugues A., Gehring U., Bergström A., Mason D., Chatzi L., Porta D., Lodrup Carlsen K.C., Baïz N., Madore A.M., Alenius H., van Rijkom B., Jankipersadsing S.A., van der V, Kull I., van Hage M., Bustamante M., Lertxundi A., Torrent M., Santorelli G., Fantini M.P., Hovland V., Pesce G., Fyhrquist N., Laatikainen T., Nawijn M.C., Li Y., Wijmenga C., Netea M.G., Bousquet J., Anto J.M., Laprise C., Haahtela T., Annesi-Maesano I., Carlsen K.H., Gori D., Kogevinas M., Wright J., Söderhäll C., Vonk J.M., Sunyer J., ... , Melén E., Koppelman G.H. (2021)
Shared DNA methylation signatures in childhood allergy: the MeDALL study
J.Allergy Clin.Immunol., 147 (3)

Noz M.P., Bekkering S., Groh L., Nielen T.M., Lamfers E.J., Schlitzer A., El Messaoudi S., van Royen N., Huys E.H., Preijers F.W., Smeets E.M., Aarntzen E.H., Zhang B., Li Y., Bremmers M.E., van der Velden W.J., Dolstra H., Joosten L.A., Gomes M.E., ... , Netea M.G., Riksen N.P. (2020)
Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease
eLife, 9

Raijmakers R.P.H., Roerink M.E., Jansen A.F.M., Keijmel S.P., Gacesa R., Li Y., Joosten L.A.B., Van Der Meer J.W.M., Netea M.G., ... , Bleeker-Rovers C.P., Xu C.J. (2020)
Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome
J.Transl.Med., 18 (1)

Bonaguro L., Köhne M., Schmidleithner L., Schulte-Schrepping J., Warnat-Herresthal S., Horne A., Kern P., Günther P., Ter Horst R., Jaeger M., Rahmouni S., Georges M., Falk C.S., Li Y., Mass E., Beyer M., Joosten L.A.B., Netea M.G., Ulas T., ... , Schultze J.L., Aschenbrenner A.C. (2020)
CRELD1 modulates homeostasis of the immune system in mice and humans
Nat.Immunol., 21 (12)

van der Graaf A., Claringbould A., Rimbert A., Heijmans B.T., Hoen P.A.C., van Meurs J.B.J., Jansen R., Franke L., Westra H.J., Li Y., Wijmenga C., ... , Sanna S., BIOS Consortium (2020)
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids
Nat.Commun., 11 (1)

Schulte-Schrepping J., Reusch N., Paclik D., Baßler K., Schlickeiser S., Zhang B., Krämer B., Krammer T., Brumhard S., Bonaguro L., De Domenico E., Wendisch D., Grasshoff M., Kapellos T.S., Beckstette M., Pecht T., Saglam A., Dietrich O., Mei H.E., Schulz A.R., Conrad C., Kunkel D., Vafadarnejad E., Xu C.J., Horne A., Herbert M., Drews A., Thibeault C., Pfeiffer M., Hippenstiel S., Hocke A., Müller-Redetzky H., Heim K.M., Machleidt F., Uhrig A., Bosquillon de Jarcy L., Jürgens L., Stegemann M., Glösenkamp C.R., Volk H.D., Goffinet C., Landthaler M., Wyler E., Georg P., Schneider M., Dang-Heine C., Neuwinger N., Kappert K., Tauber R., Corman V., Raabe J., Kaiser K.M., Vinh M.T., Rieke G., Meisel C., Ulas T., Becker M., Geffers R., Witzenrath M., Drosten C., Suttorp N., von Kalle C., Kurth F., Händler K., Schultze J.L., Aschenbrenner A.C., Li Y., Nattermann J., Sawitzki B., Saliba A.E., Sander L.E., Angelov A., Bals R., Bartholomäus A., Becker A., Bezdan D., Bonifacio E., Bork P., Clavel T., Colome-Tatche M., Diefenbach A., Dilthey A., Fischer N., Förstner K., Frick J.S., Gagneur J., Goesmann A., Hain T., Hummel M., Janssen S., Kalinowski J., Kallies R., Kehr B., Keller A., Kim-Hellmuth S., Klein C., Kohlbacher O., Korbel J.O., Kurth I., Ludwig K., Makarewicz O., Marz M., McHardy A., Mertes C., Nöthen M., Nürnberg P., Ohler U., Ossowski S., Overmann J., Peter S., Pfeffer K., Poetsch A.R., Pühler A., Rajewsky N., Ralser M., Rieß O., Ripke S., Nunes da Rocha U., Rosenstiel P., Schiffer P., Schulte E.C., Sczyrba A., Stegle O., Stoye J., Theis F., Vehreschild J., Vogel J., von Kleist M., Walker A., Walter J., Wieczorek D., ... , Ziebuhr J., Deutsche C.O.V.I. (2020)
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
Cell, 182 (6)

Sanchez-Maldonado J.M., Campa D., Springer J., Badiola J., Niazi Y., Moniz-Diez A., Hernandez-Mohedo F., Gonzalez-Sierra P., Ter Horst R., Macauda A., Brezina S., Cunha C., Lackner M., Lopez-Nevot M.A., Fianchi L., Pagano L., Lopez-Fernandez E., Potenza L., Luppi M., Moratalla L., Rodriguez-Sevilla J.J., Fonseca J.E., Tormo M., Solano C., Clavero E., Romero A., Li Y., Lass-Flörl C., Einsele H., Vazquez L., Loeffler J., Hemminki K., Carvalho A., Netea M.G., Gsur A., Dumontet C., Canzian F., Försti A., ... , Jurado M., Sainz J. (2020)
Host immune genetic variations influence the risk of developing acute myeloid leukaemia: results from the NuCLEAR consortium
Blood Cancer J., 10 (7)

Ter Horst R., Van Den Munckhof I.C.L., Schraa K., Aguirre-Gamboa R., Jaeger M., Smeekens S.P., Brand T., Lemmers H., Dijkstra H., Galesloot T.E., De Graaf J., Xavier R.J., Li Y., Joosten L.A.B., Rutten J.H.W., ... , Netea M.G., Riksen N.P. (2020)
Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity
Arterioscler.Thromb.Vasc.Biol., 40 (7)

Aguirre-Gamboa R., de Klein N., di Tommaso J., Claringbould A., van der Wijst M.G., de Vries D., Brugge H., Oelen R., Vosa U., Zorro M.M., Chu X., Bakker O.B., Borek Z., Ricano-Ponce I., Deelen P., Xu C.J., Swertz M., Jonkers I., Withoff S., Joosten I., Sanna S., Kumar V., Koenen H.J.P.M., Joosten L.A.B., Netea M.G., Wijmenga C., Franke L., ... , Li Y., BIOS Consortium (2020)
Deconvolution of bulk blood eQTL effects into immune cell subpopulations
BMC Bioinformatics, 21 (1)

Cirovic B., de Bree L.C.J., Groh L., Blok B.A., Chan J., van der Velden W.J.F.M., Bremmers M.E.J., van Crevel R., Händler K., Picelli S., Schulte-Schrepping J., Klee K., Oosting M., Koeken V.A.C.M., van Ingen J., Li Y., Benn C.S., Schultze J.L., Joosten L.A.B., Curtis N., ... , Netea M.G., Schlitzer A. (2020)
BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment
Cell Host.Microbe, 28 (2)

Keating S.T., Groh L., van der Heijden C.D.C.C., Rodriguez H., dos Santos J.C., Fanucchi S., Okabe J., Kaipananickal H., van Puffelen J.H., Helder L., Noz M.P., Matzaraki V., Li Y., de Bree L.C.J., Koeken V.A.C.M., Moorlag S.J.C.F., Mourits V.P., Bulthuis E.P., Koopman W.J.H., Mhlanga M., El-Osta A., ... , Joosten L.A.B., Netea M.G. (2020)
The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by b[beta]-Glucan
Cell Rep., 31 (3)

Zorro M.M., Aguirre-Gamboa R., Mayassi T., Ciszewski C., Barisani D., Hu S., Weersma R.K., Withoff S., Li Y., Wijmenga C., ... , Jabri B., Jonkers I.H. (2020)
Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes
J.Autoimmun., 108 (March)

Samus M., Li Y.T., Sorokin L., Rottner K., Vestweber D. (2020)
Actin-binding protein cortactin promotes pathogenesis of experimental autoimmune encephalomyelitis by supporting leukocyte infiltration into the central nervous system
J.Neurosci., 40 (7)

Wiegand S.B., Beggel B., Wranke A., Aliabadi E., Jaroszewicz J., Xu C.J., Li Y., Manns M.P., Lengauer T., Wedemeyer H., Kraft A.R.M., ... , Falk C.S., Cornberg M. (2019)
Soluble immune markers in the different phases of chronic hepatitis B virus infection
Sci Rep, 9 (1)

Wang X., Zhou Y., Tang D., Zhu Z., Li Y., Huang T., Müller R., ... , Yu W., Li P. (2019)
ACC1 (Acetyl Coenzyme A Carboxylase 1) Is a Potential Immune Modulatory Target of Cerebral Ischemic Stroke
Stroke, 50 (7)

Hong Z., Bolard A., Giraud C., Prévost S., Genta-Jouve G., Deregnaucourt C., Häußler S., ... , Jeannot K., Li Y. (2019)
Azetidine-Containing Alkaloids Produced by a Quorum-Sensing Regulated Nonribosomal Peptide Synthetase Pathway in Pseudomonas aeruginosa
Angewandte Chemie - International Edition, 58 (10)

Schultz K., Grieger C., Li Y., Ruschel A., Minnich K., Bruder D., ... , Gereke M., Sechi A. (2018)
Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44-/- tumor cells, MEFs and macrophages
PLoS ONE, 13 (12)

el Mouali Y., Gaviria-Cantin T., Sanchez-Romero M.A., Gibert M., Westermann A.J., ... , Vogel J., Balsalobre C. (2018)
CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level
PLoS.Genet., 14 (6)

Wang X., Zhou H., Chen H., Jing X., Zheng W., Li R., Sun T., Liu J., Fu J., Huo L., Li Y.Z., Shen Y., Ding X., Müller R., ... , Bian X., Zhang Y. (2018)
Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species
Proc.Natl.Acad.Sci.U.S.A., 115 (18)

Bian X., Tang B., Yu Y., Tu Q., Gross F., Wang H., Li A., Fu J., Shen Y., Li Y.Z., Stewart A.F., Zhao G., Ding X., ... , Müller R., Zhang Y. (2017)
Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029
ACS Chem.Biol., 12 (7)

Kindler E., Gil-Cruz C., Spanier J., Li Y., Wilhelm J., Rabouw H.H., Zust R., Hwang M., V'kovski P., Stalder H., Marti S., Habjan M., Cervantes-Barragan L., Elliot R., Karl N., Gaughan C., van Kuppeveld F.J., Silverman R.H., Keller M., Ludewig B., Bergmann C.C., Ziebuhr J., Weiss S.R., ... , Kalinke U., Thiel V. (2017)
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication
PLoS Pathog., 13 (2)

Fu C., Auerbach D., Li Y., Scheid U., Luxenburger E., Garcia R., ... , Irschik H., Müller R. (2017)
Solving the Puzzle of One-Carbon Loss in Ripostatin Biosynthesis
Angew.Chem.Int.Ed Engl., 56 (8)

Tu Q., Yin J., Fu J., Herrmann J., Li Y., Yin Y., Stewart A.F., ... , Müller R., Zhang Y. (2016)
Room temperature electrocompetent bacterial cells improve DNA transformation and recombineering efficiency
Sci.Rep., 6

Kyu H.H., Pinho C., Wagner J.A., Brown J.C., Bertozzi-Villa A., Charlson F.J., Coffeng L.E., Dandona L., Erskine H.E., Ferrari A.J., Fitzmaurice C., Fleming T.D., Forouzanfar M.H., Graetz N., Guinovart C., Haagsma J., Higashi H., Kassebaum N.J., Larson H.J., Lim S.S., Mokdad A.H., Moradi-Lakeh M., Odell S.V., Roth G.A., Serina P.T., Stanaway J.D., Misganaw A., Whiteford H.A., Wolock T.M., Wulf Hanson S., bd-Allah F., Abera S.F., bu-Raddad L.J., AlBuhairan F.S., Amare A.T., Antonio C.A., Artaman A., Barker-Collo S.L., Barrero L.H., Benjet C., Bensenor I.M., Bhutta Z.A., Bikbov B., Brazinova A., Campos-Nonato I., Castaneda-Orjuela C.A., Catala-Lopez F., Chowdhury R., Cooper C., Crump J.A., Dandona R., Degenhardt L., Dellavalle R.P., Dharmaratne S.D., Faraon E.J., Feigin V.L., Furst T., Geleijnse J.M., Gessner B.D., Gibney K.B., Goto A., Gunnell D., Hankey G.J., Hay R.J., Hornberger J.C., Hosgood H.D., Hu G., Jacobsen K.H., Jayaraman S.P., Jeemon P., Jonas J.B., Karch A., Kim D., Kim S., Kokubo Y., Kuate Defo B., Kucuk Bicer B., Kumar G.A., Larsson A., Leasher J.L., Leung R., Li Y., Lipshultz S.E., Lopez A.D., Lotufo P.A., Lunevicius R., Lyons R.A., Majdan M., Malekzadeh R., Mashal T., Mason-Jones A.J., Melaku Y.A., Memish Z.A., Mendoza W., Miller T.R., Mock C.N., Murray J., Nolte S., Oh I.H., Olusanya B.O., Ortblad K.F., Park E.K., Paternina Caicedo A.J., Patten S.B., Patton G.C., Pereira D.M., Perico N., Piel F.B., Polinder S., Popova S., Pourmalek F., Quistberg D.A., Remuzzi G., Rodriguez A., Rojas-Rueda D., Rothenbacher D., Rothstein D.H., Sanabria J., Santos I.S., Schwebel D.C., Sepanlou S.G., Shaheen A., Shiri R., Shiue I., Skirbekk V., Sliwa K., Sreeramareddy C.T., Stein D.J., Steiner T.J., Stovner L.J., Sykes B.L., Tabb K.M., Terkawi A.S., Thomson A.J., Thorne-Lyman A.L., Towbin J.A., Ukwaja K.N., Vasankari T., Venketasubramanian N., Vlassov V.V., Vollset S.E., Weiderpass E., Weintraub R.G., Werdecker A., Wilkinson J.D., Woldeyohannes S.M., Wolfe C.D., Yano Y., Yip P., Yonemoto N., Yoon S.J., Younis M.Z., Yu C., El Sayed Zaki M., Naghavi M., ... , Murray C.J., Vos T. (2016)
Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013: Findings From the Global Burden of Disease 2013 Study
JAMA Pediatr., 170 (3)

Yuan D., Zhu Z., Tan X., Liang J., Zeng C., Zhang J., Chen J., Ma L., Dogan A., Brockmann G., Goldmann O., Medina E., Rice A.D., Moyer R.W., Man X., Yi K., Li Y., Lu Q., ... , Huang Y., Huang S. (2014)
Scoring the collective effects of SNPs: association of minor alleles with complex traits in model organisms
Science China Life Sciences, 57

Murray C.J., Ortblad K.F., Guinovart C., Lim S.S., Wolock T.M., Roberts D.A., Dansereau E.A., Graetz N., Barber R.M., Brown J.C., Wang H., Duber H.C., Naghavi M., Dicker D., Dandona L., Salomon J.A., Heuton K.R., Foreman K., Phillips D.E., Fleming T.D., Flaxman A.D., Phillips B.K., Johnson E.K., Coggeshall M.S., bd-Allah F., Abera S.F., Abraham J.P., Abubakar I., bu-Raddad L.J., bu-Rmeileh N.M., Achoki T., Adeyemo A.O., Adou A.K., Adsuar J.C., Agardh E.E., Akena D., Al Kahbouri M.J., Alasfoor D., Albittar M.I., cala-Cerra G., Alegretti M.A., Alemu Z.A., fonso-Cristancho R., Alhabib S., Ali R., Alla F., Allen P.J., Alsharif U., Alvarez E., vis-Guzman N., Amankwaa A.A., Amare A.T., Amini H., Ammar W., Anderson B.O., Antonio C.A., Anwari P., Arnlov J., Arsenijevic V.S., Artaman A., Asghar R.J., Assadi R., Atkins L.S., Badawi A., Balakrishnan K., Banerjee A., Basu S., Beardsley J., Bekele T., Bell M.L., Bernabe E., Beyene T.J., Bhala N., Bhalla A., Bhutta Z.A., Abdulhak A.B., Binagwaho A., Blore J.D., Basara B.B., Bose D., Brainin M., Breitborde N., Castaneda-Orjuela C.A., Catala-Lopez F., Chadha V.K., Chang J.C., Chiang P.P., Chuang T.W., Colomar M., Cooper L.T., Cooper C., Courville K.J., Cowie B.C., Criqui M.H., Dandona R., Dayama A., De Leo D., Degenhardt L., Del Pozo-Cruz B., Deribe K., Des Jarlais D.C., Dessalegn M., Dharmaratne S.D., Dilmen U., Ding E.L., Driscoll T.R., Durrani A.M., Ellenbogen R.G., Ermakov S.P., Esteghamati A., Faraon E.J., Farzadfar F., Fereshtehnejad S.M., Fijabi D.O., Forouzanfar M.H., Fra Paleo U., Gaffikin L., Gamkrelidze A., Gankpe F.G., Geleijnse J.M., Gessner B.D., Gibney K.B., Ginawi I.A., Glaser E.L., Gona P., Goto A., Gouda H.N., Gugnani H.C., Gupta R., Gupta R., Hafezi-Nejad N., Hamadeh R.R., Hammami M., Hankey G.J., Harb H.L., Haro J.M., Havmoeller R., Hay S.I., Hedayati M.T., Pi I.B., Hoek H.W., Hornberger J.C., Hosgood H.D., Hotez P.J., Hoy D.G., Huang J.J., Iburg K.M., Idrisov B.T., Innos K., Jacobsen K.H., Jeemon P., Jensen P.N., Jha V., Jiang G., Jonas J.B., Juel K., Kan H., Kankindi I., Karam N.E., Karch A., Karema C.K., Kaul A., Kawakami N., Kazi D.S., Kemp A.H., Kengne A.P., Keren A., Kereselidze M., Khader Y.S., Khalifa S.E., Khan E.A., Khang Y.H., Khonelidze I., Kinfu Y., Kinge J.M., Knibbs L., Kokubo Y., Kosen S., Defo B.K., Kulkarni V.S., Kulkarni C., Kumar K., Kumar R.B., Kumar G.A., Kwan G.F., Lai T., Balaji A.L., Lam H., Lan Q., Lansingh V.C., Larson H.J., Larsson A., Lee J.T., Leigh J., Leinsalu M., Leung R., Li Y., Li Y., De Lima G.M., Lin H.H., Lipshultz S.E., Liu S., Liu Y., Lloyd B.K., Lotufo P.A., Machado V.M., Maclachlan J.H., Magis-Rodriguez C., Majdan M., Mapoma C.C., Marcenes W., Marzan M.B., Masci J.R., Mashal M.T., Mason-Jones A.J., Mayosi B.M., Mazorodze T.T., Mckay A.C., Meaney P.A., Mehndiratta M.M., Mejia-Rodriguez F., Melaku Y.A., Memish Z.A., Mendoza W., Miller T.R., Mills E.J., Mohammad K.A., Mokdad A.H., Mola G.L., Monasta L., Montico M., Moore A.R., Mori R., Moturi W.N., Mukaigawara M., Murthy K.S., Naheed A., Naidoo K.S., Naldi L., Nangia V., Narayan K.M., Nash D., Nejjari C., Nelson R.G., Neupane S.P., Newton C.R., Ng M., Nisar M.I., Nolte S., Norheim O.F., Nowaseb V., Nyakarahuka L., Oh I.H., ... , Ohkubo T., Olusanya B.O. (2014)
Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
Lancet, 384 (9947)

Zou C.J., Zhu L.J., Li Y.H., Mo Y.Q., Zheng D.H., Ma J.D., Ou-Yang X., ... , Pessler Frank, Dai L. (2013)
The association between hepatitis B virus infection and disease activity, synovitis, or joint destruction in rheumatoid arthritis
Clinical Rheumatology, 32 (6)

Li Y., Luxenburger E., Müller Rolf (2013)
An Alternative Isovaleryl CoA Biosynthetic Pathway Involving a Previously Unknown 3-Methylglutaconyl CoA Decarboxylase
Angewandte Chemie International Edition, 52 (4)

Katsuyama Y., Harmrolfs K., Pistorius D., Li Y., Müller Rolf (2012)
A Semipinacol Rearrangement Directed by an Enzymatic System Featuring Dual-Function FAD-Dependent Monooxygenase
Angewandte Chemie International Edition, 51 (37)

Pistorius D., Li Y., Sandmann A., Müller Rolf* (2011)
Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15
Molecular BioSytems, 7 (12)

Pistorius D., Li Y., Mann S., Müller Rolf* (2011)
Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis
Journal of the American Chemical Society, 133 (32)

Kukita A., Kukita T., Nagata K., Teramachi J., Li Y.J., Yoshida H., Miyamoto H., Gay S., ... , Pessler Frank*, Shobuike T. (2011)
The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo
Arthritis and Rheumatism, 63 (9)

Li Y., Weissman K.J., Müller Rolf* (2010)
Insights into multienzyme docking in hybrid PKS-NRPS megasynthetases revealed by heterologous expression and genetic engineering
ChemBioChem, 11 (8)

Tzeneva V.A., Li Y., Felske A.D., de Vos W.M., Akkermans A.D., ... , Vaughan E.E., Smidt H. (2004)
Development and application of a selective PCR-denaturing gradient gel electrophoresis approach to detect a recently cultivated Bacillus
Applied and Environmental Microbiology, 70 (10)

Wagner-Döbler I., von Canstein H.F., Li Y., Leonhäuser J., Deckwer W.-D. (2003)
Process-integrated microbial mercury removal from wastewater of chlor-alkali electrolysis plants
Engineering in Life Sciences, 3 (4)

von Canstein H.F., Li Y., Leonhäuser J., Deckwer W.-D., Wagner-Döbler I. (2003)
Mikrobielle Reinigung von quecksilberhaltigen Industrieabwässern
Biospektrum, (2/3)

von Canstein H.F., Li Y., Leonhäuser J., Deckwer W.-D., Wagner-Döbler I. (2003)
Bioremediation of mercury-polluted industrial wastewater by mercury-reducing biofilms
Recent Research Developments in Biotechnology and Bioengineering, 5

Wagner-Döbler I., Von Canstein H., Li Y., Leonhäuser J., Deckwer W.D. (2002)
Process-integrated removal of mercury from chlor-alkali electrolysis by microorganisms
Chemie Ingenieur Technik, 74 (4)

Wagner-Döbler I., Von Canstein H., Leonhäuser J., Li Y., Deckwer W-D. (2002)
Prozessintegrierte Quecksilberentfernung aus Abwässern der Chloralkali-Elektrolyse durch Mikroorganismen.
Chemie Ingenieur Technik, 74

Von Canstein H., Kelly S., Li Y., Wagner-Döbler I. (2002)
Species diversity improves the efficiency of mercury-reducing biofilms under changing environmental conditions
Applied and Environmental Microbiology, 68 (6)

Von Canstein H., Li Y., Leonhauser J., Haase E., Felske A., ... , Deckwer W.D., Wagner-Döbler I. (2002)
Spatially oscillating activity and microbial succession of mercury-reducing biofilms in a technical-scale bioremediation system
Applied and Environmental Microbiology, 68 (4)

von Canstein H.F., Li Y., Wagner-Döbler I. (2001)
Long-term stability of mercury-reducing microbial biofilm communities analyzed by 16s-23s rDNA interspacer region polymorphism
Microbial Ecology, 42 (4)

Von Canstein H., Li Y., Wagner-Döbler I. (2001)
Long-term performance of bioreactors cleaning mercury- contaminated wastewater and their response to temperature and mercury stress and mechanical perturbation
Biotechnology and Bioengineering, 74 (3)

Felske A., Pauling B.V., von Canstein H.F., Li Y., Lauber J., ... , Buer J., Wagner-Döbler I. (2001)
Detection of small sequence differences using competitive PCR: molecular monitoring of genetically improved, mercury-reducing bacteria
Biotechniques, 30 (1)

Wagner-Döbler I., Von Canstein H., Li Y., Felske A., Pauling B. (2000)
Mercury remediation - a new solution to an old problem- Remediation of hazardous waste - environmental protection technologies

Wagner-Döbler I., Von Canstein H., Lünsdorf H., Li Y., Felske A., Pauling B. (2000)
Bioremediation of electrolysis wastewater by mercury resistant Pseudomonas strains

Wagner-Döbler I., Von Canstein H., Li Y. (2000)
Bioremediation of mercury contaminated wastewater
Bioworld

Wagner-Döbler I., Von Canstein H., Li Y., Timmis K.N., Deckwer W.D. (2000)
Removal of mercury from chemical wastewater by microoganisms in technical scale
Environmental Science & Technology, 34 (21)

Wagner-Döbler I., Lünsdorf H., Lubbehusen T., von Canstein H.F., Li Y. (2000)
Structure and species composition of mercury-reducing biofilms
Applied and Environmental Microbiology, 66 (10)

Ben-Asouli Y., Banai Y., Hauser H., Kaempfer R. (2000)
Recognition of 5'-terminal TAR structure in human immunodeficiency virus-1 mRNA by eukaryotic translation initiation factor 2
Nucleic Acids Research, 28 (4)