Chronic lung infections caused by the bacterium Pseudomonas aeruginosa require complex and, in most cases, long-term treatment with antibiotics. It is generally not possible to completely heal the infection or even...
To be able to develop new drugs against infectious diseases researchers need to understand their molecular basis. How does the proliferation of a pathogen proceed, what interactions take place between it and the host...
In recent years, more and more pathogens have become resistant to previously time-proven antibiotics. This scenario gives scientists all over the world cause to find new anti-infective substances and to develop them for...
Intestinal bacteria are suspected of causing cardiovascular disease, since they produce trimethylamine as a metabolic product that is hazardous to humans. They utilise food ingredients that are present mainly in meat...
Cells inside the human body contain a flexible polymer network called the cytoskeleton which consists of actin filaments - and other components - and undergoes constant assembly and disassembly. This turnover of actin...
Stem cells in the bone marrow provide a life-long supply of blood and immune cells. If they display defects – either caused by hereditary diseases or blood cancer – the transplantation of bone marrow cells of a suitable...
There is a continuing need for effective vaccinations against viruses which specifically infect the liver. According to the World Health Organization WHO, approximately 400 million people around the world are infected...
Scientists studying infections used to focus mainly on the direct interaction of the immune system with pathogens, but have since moved on to look more closely at the interactions that go on between microbiota, immune...
Many bacteria move by rotating long, thin filaments called flagella. Flagella are made of several tens of thousands building blocks outside the bacterial cell and grow up to ten times longer than the bacterial cell...
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