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Molecular Principles of RNA Phages
The research group led by Jens Hör investigates the dynamics of infection, host takeover, and anti-phage defense during the interaction between RNA phages and their hosts. They seek to understand the molecular principles underlying these processes to develop new and improved antibacterial strategies such as phage therapy.
Central Facility for Microscopy
Light microscopy and electron microscopy are excellent high resolution tools to investigate the adhesion and invasion mechanisms of pathogenic bacteria. High resolution electron microscopy permits to examine and unravel pathogenicity mechanisms on a morphological basis. ZEIM offers equipment and highly sophisticated expertise for the preparation and observation of biological samples.
Core Facility of Comparative Medicine
To be able to investigate diseases, understand the relationships between pathogens and their host and to develop novel strategies against pathogens, the scientists at the HZI depend on experiments that involve the use of laboratory animals. For this purpose, the HZI operates a central animal facility on campus. The primary task of this service unit is the breeding and keeping of laboratory mice as well as provision of services for the scientists of the HZI, centered around laboratory animal science.
Transgenic Mice
Genetically modified mice can provide information about the function of particular genes or individual genetic elements. Further, they can be specifically designed to mimic certain physiologic or pathologic conditions. The Service Unit "Transgenic Mice" (TGSM) creates such genetically modified mice for researchers of the center.
Research Groups
Research groups Topic overview Bacterial and viral pathogens Immune Response and Interventions Anti-Infectives Technology Platforms Bacterial and viral pathogens The Topic "Bacterial and Viral Pathogens" focuses on the role of pathogenic bacteria and…
Prof Dr Jörg Vogel
Prof Dr Jörg Vogel Head of Research Group +49 931 31 82575 E-Mail Prof. Jörg Vogel is the founding director of the Helmholtz Institute for RNA-based Infection Research (HIRI) as well as the director of the Institute of Molecular Infection Biology (IMIB) at…
Prof Dr Chase Beisel
Prof Dr Chase Beisel Research Group Leader +49 93131-85346 E-Mail Chase Beisel received his bachelors and doctoral degrees in chemical engineering, although he always maintained an interest in engineering biomolecules and biological systems. His doctoral…
Prof Dr Antoine-Emmanuel Saliba
Prof Dr Antoine-Emmanuel Saliba Head of Research Group +49 931 31 81341 E-Mail Antoine-Emmanuel Saliba studied biochemical engineering at INSA Toulouse (France) and received his PhD in the research group of Jean-Louis Viovy at the Institut Curie (Paris,…
Prof Dr Mathias Munschauer
Prof Dr Mathias Munschauer Head of Research Group +49 931- 86951 E-Mail Mathias Munschauer started working with RNA and RNA-binding proteins as an undergraduate student in the lab of Thomas Tuschl at Rockefeller University in New York (USA), where he also…
Dr Redmond Smyth
Dr Redmond Smyth Research Group Leader +49 931 31 89152 E-Mail Redmond Smyth carried out his undergraduate degree in Natural Sciences at the University of Cambridge (UK), specializing in Virology and Immunology. He then moved to the Burnet Institute,…
