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Displaying results 101 to 110 of 231.
Innovation Management
Innovation Management and Technology Transfer Transfer strategy The transfer of research results into medical and pharmaceutical applications plays a central role at the HZI. In addition to scientific exchange, the aim is to pave the way for the transfer of…
Third-Party Funds Acquisition
Third-Party Funds Acquisition With more than 20 years of experience and expertise as multipliers and service providers, the members of the staff unit Third-Party Funds Acquisition (DA) advise and support the scientific staff of the HZI, the DSMZ (German…
Administration and Infrastructure
Administration and Infrastructure The administrative units and staff units of the administration and infrastructure support the scientific work at the HZI. Approximately 200 people are employed in the administration of the HZI across all locations (as of…
Computational Biology for Infection Research
The Department of “Computational Biology for Infection Research” studies the human microbiome, viral and bacterial pathogens, and human cell lineages within individual patients by analysis of large-scale biological and epidemiological data sets with computational techniques. Focusing on high throughput meta’omics, population genomic and single cell sequencing data, we produce testable hypotheses, such as sets of key sites or relevant genes associated with the presence of a disease, of antibiotic resistance or pathogenic evasion of immune defense. We interact with experimental collaborators to verify our findings and to promote their translation into medical treatment or diagnosis procedures. To achieve its research goals, the department also develops novel algorithms and software.
Safety and environmental protection
Safety and Environmental Affairs The department for safety and environmental affairs takes over the central duties for occupational health and safety (OHS) and environmental affairs that should not be delegated to the heads of the departments of the…
Scientific strategy
Scientific Strategy The Staff Unit Scientific Strategy (WST) supports the management and the scientific steering committee in developing and implementing the centre's strategy. WST coordinates the preparation of scientific-strategic concepts and…
Strategic Communication
Strategic Communication The strategy departments work on behalf of the management and in close cooperation with colleagues from research and administration. The main goal is to make concepts for the scientific development of the HZI. The Task of the…
Biostatistics
High-Throughput-technologies generate large amounts of data. The drawback: these biological and medical data must be processed to results with statistical methods and models. Concepts from robust and computational statistics as well as visualisation techniques help to better understand, estimate and cope with the uncertainty and strong variation that are often inherent in biological and medical data. The project group „Biostatistics“ is part of the research group „Cellular Proteome Research” which is led by Lothar Jänsch.
Pathogen Evolution
Ecological interactions that underpin human life are highly dynamic, and changes in complex ecosystems can have far-reaching consequences on human health. Therefore, One Health also has a very strong evolutionary component. Over the last decades, evolutionary biology concepts have provided a major contribution towards unveiling the short- and long-term dynamics of pathogen emergence and spread. The importance of evolutionary approaches has become particularly evident during the COVID-19 pandemic. Both the initial emergence event and the later spread and evolution of SARS-CoV-2 have been investigated using evolutionary genomics – with the rise of variants of concern (VOC) being pointed out in the first place by observational data and inferential statistics. The Department of Pathogen Evolution studies both current and historical samples and uses them to make targeted predictions about the potential spread of important pathogens, thus providing important contributions to public health. The department is located at the Helmholtz Institute for One Health .
Biosafety Level 3 Laboratory
Biological agents of risk group 3 (RG3) pose a constant global as well as national challenge because they cause severe illnesses in humans against which there are usually no effective preventive or treatment measures. Since these pathogens can only be handled in special biosafety level 3 (BSL3) laboratories, the modern BSL3 laboratories at the HZI provide a technology platform that is indispensable in today's infection research - only in this way can our scientists develop new therapies, prevention measures or diagnostic procedures against these pathogens.
