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Displaying results 91 to 100 of 231.

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Prof Dr Lothar Jänsch

Prof Dr Lothar Jänsch Head of Research Group +49 531 6181-3030 E-Mail Prof Dr Lothar Jänsch Lothar Jänsch studied biology at the Free University of Berlin and in 1995 prepared his diploma thesis at the IGF in Berlin. After that, he worked as a PhD student…

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Prof Dr Ursula Bilitewski

Prof Dr Ursula Bilitewski Head of Research Group +49 531 6181-1010 E-Mail Prof Dr Ursula Bilitewski Ursula Bilitewski studied chemistry at the University of Münster, earning her Ph.D. at the Institute of Physical Chemistry. After spending another year at…

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Innovation Management

Innovation Management and Technology Transfer Transfer strategy The transfer of research results into medical and pharmaceutical applications plays a central role at the HZI. In addition to scientific exchange, the aim is to pave the way for the transfer of…

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Third-Party Funds Acquisition

Third-Party Funds Acquisition With more than 20 years of experience and expertise as multipliers and service providers, the members of the staff unit Third-Party Funds Acquisition (DA) advise and support the scientific staff of the HZI, the DSMZ (German…

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Administration and Infrastructure

Administration and Infrastructure The administrative units and staff units of the administration and infrastructure support the scientific work at the HZI. Approximately 200 people are employed in the administration of the HZI across all locations (as of…

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Safety and environmental protection

Safety and Environmental Affairs The department for safety and environmental affairs takes over the central duties for occupational health and safety (OHS) and environmental affairs that should not be delegated to the heads of the departments of the…

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Scientific strategy

Scientific Strategy The Staff Unit Scientific Strategy (WST) supports the management and the scientific steering committee in developing and implementing the centre's strategy. WST coordinates the preparation of scientific-strategic concepts and…

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Strategic Communication

Strategic Communication The strategy departments work on behalf of the management and in close cooperation with colleagues from research and administration. The main goal is to make concepts for the scientific development of the HZI. The Task of the…

Research Group

Integrative Informatics for Infection Biology

Recent years have seen accelerating development of high-throughput technologies in infection biology. Now, thousands of genetic loci can be simultaneously interrogated in a single experiment, providing an array of measurements of transcription, translation, regulatory interactions, and fitness effects. The bottleneck in advancing our understanding of pathogens now lies in moving from hypothesis-free screening through data integration to hypothesis generation. We develop new statistical, computational, and visualization approaches to overcome this bottleneck in the interpretation of complex post-genomic data. This group is located at the Helmholtz Institute for RNA-based Infection Research (HIRI).

Research Group

Genome Architecture and Evolution of RNA Viruses

RNA viruses are a major threat to human health and responsible for millions of deaths each year. Their replication is orchestrated by the RNA genome, which encodes for viral proteins needed to hijack the host cell. Traditionally, infectious disease research has focused on blocking viral replication by inhibiting these proteins. However, we now appreciate that the genomes of RNA viruses are not just passive carriers of protein coding information, but active participants in the viral infection process through the action of non-coding RNA. We study the structure and function of viral non-coding RNA, with the goal of harnessing the resulting knowledge in the design of next generation RNA-based therapies. This group is located at the Helmholtz Institute for RNA-based Infection Research (HIRI) .