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Displaying results 671 to 677 of 677.

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Universal Flu Vaccine Candidate Protects Against Infection in Animal Models

Researchers at Cleveland Clinic’s Lerner Research Institute and the HZI have reported that their universal flu vaccine candidate elicited a strong immune response and provided protection against severe infection and rapid clearance after viral exposure in ferrets. This…

10.09.2024
Research Group

Innate Immunity and Infection

The moment a pathogen, which has successfully entered the body, is recognized, the body quickly mobilizes its defenses. Interferons are molecules that are counted among the body’s first line of defense. They prevent proliferation and the spread of viruses in the body and serve to alert the immune system. Read here about the different ways we use to try and decode this system, all in an effort to find new approaches to infectious disease prevention and therapy.

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Enter the world of infection research - Open Day at the HZI

During guided tours, HZI researchers explain, for example, how new active substances against infections can be developed from natural products or how they use epidemiological studies to understand the spread of diseases and contribute to the health of the population. In…

12.09.2024
Research Group

Anti-infectives from Microbiota

The department of Prof Christine Beemelmanns focuses on the identification and functional analysis of novel anti-infective natural products from microbial communities. Co-cultivation studies as well as cell-based assays in combination with chemical-analytical and molecular-biological methods are used to evaluate and prioritize novel natural product producers. The department uses established and innovative metabolomic-, activity and genome-based methods to identify and determine the structure of the secreted natural products. Based on the isolated novel natural substances, the functional analysis and evaluation of their range of effects is carried out. This department is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) .

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Why the flu vaccine is less effective in older people

Every year at the beginning of October, the flu epidemic rolls around. “Because older people in particular have an increased risk of a severe course of the disease, effective vaccines are especially important for them,” says Prof. Yang Li, Scientific Director of the…

30.09.2024