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Displaying results 81 to 83 of 83.
Structural Infection Biology
To understand and eventually manipulate pathways that control the interaction of pathogens (e.g. bacteria, virus, parasite) with their hosts (e.g. human, plants) requires an interdisciplinary research approach, which often combines different fields of research such as cell biology and microbiology. In our laboratory, however, we take a closer look at the processes occurring during an infection at the cellular and atomic level by harnessing a variety of modern biophysical methods that allow addressing the spatio-temporal dynamics of an infectious disease at a high resolution. The department is located at the Center for Structural Systems Biology ( CSSB ) at the heart of the Germany’s largest accelerator center DESY (Deutsches Elektronen-Synchrotron) in Hamburg.
Synthetic biology of microbial natural products
The Bozhüyük group focuses on bacterial natural products, with unique structures and bioactive properties. The group studies modular assembly lines like polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs), which produce many essential clinical agents – but are especially valuable to develop new anti-infectives. This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) .
Systems Immunology
To see the immune system with the eyes of mathematics – that is the guiding principle of the department Systems Immunology. Mathematical models help to faster and better understand diseases that are associated with immune functions. Read here how scientists use mathematics to investigate chronic inflammatory diseases, the regulation of adaptive immune responses, and the interaction between the nervous, the endocrine and the immune system.
