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Alliance of Science Organisations condemns anti-democratic endeavours
The many protests throughout Germany are an impressive demonstration of the deep solidarity in our society. We regard the clear commitment of the many people who are visibly standing up for the fundamental values of our democracy at this time as an enormously…
New findings on Bacteroides thetaiotaomicron physiology under bile stress
Bacteroides thetaiotaomicron is an abundant member of the human intestinal microbiota. The bacterium supports the digestion of polysaccharides and is of paramount importance for human health, but it can also cause or promote infections. As a model organism, B.…
HZI Molecule Transformed into a Cancer Medicine in the United States
The pharmaceutical company Bristol-Myers Squibb (BMS) recently obtained approval in the American market for IXEMPRA, a semi-synthetic analog of epothilone B, for the treatment of patients with metastatic breast cancer resistant or refractory to anthracyclines, taxanes,…
A new Knowledge Website for Infection Research
From antibiotic resistance to zoonotic diseases, from the developing to the developed world, infectious disease remains a profound health threat. Stay abreast of the latest research in infection at the new knowledge website „Infection Research-News and Perspectives“…
Dumping Useless Genes
Bacteria are genetically equipped with tremendous variability. As a result, these microorganisms are extremely flexible in their responses to the surrounding environment. From the standpoint of biotechnology, many bacterial genes are useful, while others are not.…
Why Mice Succumb to Human Diseases
The bacterium Listeria monocytogenes is able to infect humans causing diarrhea, meningitis, still birth or miscarriage. Mice, by contrast, are largely immune. This difference may be traced to the bacterial protein Internalin (or InlA), a molecular key that provides the…
Award for Indian HZI researcher
In Kochi, India, the HZI scientist Prof Gursharan Singh Chhatwal was honoured today with the Pravasi Bharatiya Samman Award 2013. With this award, the Indian government dignifies the merits of non-resident Indians that have helped to improve the international reputation…
Natural killer cells – the body’s own patrol against viruses and tumours
Scientists at the Helmholtz Centre for Infection Research (HZI) have analysed for the first time all the proteins inside natural killer (NK) cells of healthy individuals. The newly discovered “protein repertoire” shows that these immune cells cannot only defend us…
Serum Institute of India acquires rights to German Tb vaccine
Hopes are high for a new and improved tuberculosis vaccine: Serum Institute of India is planning on taking a promising vaccine - originally developed in Germany - and introducing it into the clinical setting. Studies have shown that the new vaccine is more effective and…
3D molecular syringes
Abdominal pain, fever, diarrhoea – these symptoms could point to an infection with the bacterium Yersinia. The bacterium’s pathogenic potential is based on a syringe-like injection apparatus called injectisome. For the first time, an international team of researchers…
