#: locale=de
## Aktion
### URL
LinkBehaviour_3D2806BF_2B97_12C1_41A2_170E5D5A3494.source = https://www.helmholtz-hzi.de/en/service/data-protection/
LinkBehaviour_303CA257_2BA3_562E_41B7_343B1E507CB2.source = https://www.helmholtz-hzi.de/en/service/data-protection/
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LinkBehaviour_303F4257_2BA3_562E_41C4_BF2BE63B9F04.source = https://www.helmholtz-hzi.de/en/service/imprint/
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## Media
### Titel
panorama_9DDB10F9_8517_06AB_41C5_14766BD4F0E6.label = 0-demo
panorama_1072E2C4_30DE_B30A_4168_7D1920402A1D.label = 1-1-0_00000
panorama_10455AB6_30D9_9376_41B8_9E0D6BF9DBF8.label = 1-2-0_00000
video_2E687AD0_32A5_E30A_41AF_BB467A8B0627.label = 1-3-a DEEFlickr (VR2-Bearbeitung 1)_1
panorama_119D8769_30FA_911A_41C0_018D46E8CC5D.label = 1-3-a_00013
video_132041C5_32A3_610A_41BD_5B1498F64B93.label = 2-1-0 (VR2-Bearbeitung 1)
video_12D83552_32A3_210E_41B5_2320BE6FC530.label = 2-1-0 (VR2-Bearbeitung 2)
video_2D63CF51_32A7_210A_41B0_E292A430B5DC.label = 2-1-0 (VR2-Bearbeitung 3)
panorama_106CE52A_30FB_911E_41C4_26903493C168.label = 2-1-0_00004
panorama_10266E77_30D9_93F6_411E_CD78BB67C5A0.label = 2-2-0_00000
video_1B371132_3FA2_D606_41C4_35537AD91241.label = 3-1-a sound (VR2-Bearbeitung 1)
panorama_1048139A_30FA_913E_41BF_32A98A2C42E1.label = 3-1-a_00000
panorama_16D2DB6F_30DB_9116_41C7_DB0F53044EEC.label = 3-2-0b_00000
panorama_17FDDC60_30DA_970A_4194_D3258E51AA1B.label = 3-3-0_00000
panorama_17F4879E_30DA_F136_41B3_64A8514838D6.label = 3-4-0_00000
video_122BDEFA_329F_20FE_4184_CBDF71347BCA.label = 3-5-a (VR2-Bearbeitung 2)
panorama_17ECA0DF_30D9_6F36_41A3_4E85A91CE6D9.label = 3-5-a_00000
video_1212092A_32E3_E11E_4179_A5C6733F660A.label = 3-6-a (VR2-Bearbeitung 1)
panorama_17C509F9_30D9_F0FA_41B6_99D3BD41BE41.label = 3-6-a_00000
video_10FB6AA8_32ED_231A_4173_16E88BF07A12.label = 4-1-a (VR2-Bearbeitung 1)
panorama_1012719A_30F9_913E_41B6_6EDED9BD753E.label = 4-1-a_00000
video_10A314E5_32E5_270A_41C0_B42C8CD63947.label = 4-2-a (VR2-Bearbeitung 1)
panorama_17C6F9BC_30D9_717A_41C2_7CCF94B82462.label = 4-2-a_00000
video_10FBCA87_32E3_2316_4183_EAB3B9AABEDA.label = 4-3-a (VR2-Bearbeitung 1)_1
panorama_16F70D17_30D7_B136_41C0_BCFD105DAB01.label = 4-3-a_00000
video_10A060C6_32FF_3F16_4180_F3705777D0C8.label = 5-1-0 (VR2-Bearbeitung 1)
video_11B012A5_32E5_E30A_41B4_B1E2C313C3AD.label = 5-1-0 (VR2-Bearbeitung 2)
video_1366A750_32E4_E10A_41C4_4B07E64F0990.label = 5-1-0 (VR2-Bearbeitung 3)
panorama_105B56B3_30F9_930E_4194_62A711EDBF40.label = 5-1-0_00000
video_1E9A0C17_3FA1_AE0E_41C0_DAADDEF738A7.label = 6-1 (VR2-Bearbeitung 1)
video_2A170AE6_30DB_B316_41C1_969BF0BC4326.label = movie10_small2
video_11B8773E_313A_9176_41A2_9688B5A62B5D.label = p1_bildschirm
video_2DE4BB69_30DF_911A_4193_6A6E62F45028.label = p2_moinitor
video_10E90863_30FB_BF0E_41B2_D749D9D8FBD6.label = p2_wandbild
video_17EDF8A9_30D9_9F1A_41C4_E56ECA5039C5.label = s3_monitor
### Video
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videolevel_12C6622D_2BD1_3407_41B2_D4B8D3D442E5.url = media/video_17EDF8A9_30D9_9F1A_41C4_E56ECA5039C5_de.mp4
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### Video Untertitel
## Skin
### Button
Button_3D991D19_2429_1CDA_41AC_DE5D32FC3B99.label = Accept
Button_3D991D19_2429_1CDA_41AC_DE5D32FC3B99_mobile.label = Accept
### Image
Image_2129AAB3_34B0_6841_41C1_DF835CE2F7E6.url = skin/Image_2129AAB3_34B0_6841_41C1_DF835CE2F7E6_de.png
Image_2129AAB3_34B0_6841_41C1_DF835CE2F7E6_mobile.url = skin/Image_2129AAB3_34B0_6841_41C1_DF835CE2F7E6_mobile_de.png
Image_215B9D5D_34B0_28C1_41B0_94DFBE52B986.url = skin/Image_215B9D5D_34B0_28C1_41B0_94DFBE52B986_de.png
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Image_21E8C196_34B0_3843_41B8_77704FFED936.url = skin/Image_21E8C196_34B0_3843_41B8_77704FFED936_de.png
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Image_275D98E7_34B0_29C1_41CA_0692BE71BFCB_mobile.url = skin/Image_275D98E7_34B0_29C1_41CA_0692BE71BFCB_mobile_de.png
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### Label
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### Multiline Text
HTMLText_5C18A542_442F_E074_41B9_C1248C2510F3.html = Infected cells
Lung cells infected with SARS-CoV-2 under the fluorescence microscope: Virus particles are produced in the cytoplasm of an infected cell, which can be recognized by a green-labeled protein of the viral envelope.
Viruses through the microscope
Culture of the Vero cell line infected with influenza viruses: The infected cells die and release viruses that can infect further cells. The process results in holes in the dense cell layer. ©HZI/Bröder, Trittel
Viruses through the microscope
Uninfected control culture of the Vero cell line: Cells grow in a dense, continuous cell layer. ©HZI/Bröder, Trittel
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A grid hole at about 13,000x magnification. Now you can also see contaminations as small black dots. These are aggregated proteins as well as small ice crystals.
Data collection and processing
A grid square at about 510x magnification. Here you can see the perforated carbon film. In many of these holes - called grid holes - the protein sample is stretched in a thin liquid film.
Data collection and processing
A view of the protein sample at 150,000x magnification. Many protein particles form a ring of eight. You can also see particles from the side that look like small garden fences.
Data collection and processing
Data processing: On each captured image, protein particles are automatically detected (red circles), cut out and sorted into 2D classes. Very many detected particles together reveal more and more details (left half of the image).
Data collection and processing
Data processing: The sorted particles are now aligned three-dimensionally in space and we can calculate the electron envelope of the protein (right half of the image).
Data collection and processing
Data processing: We can then build a model of the protein into the calculated electron envelope and analyze the data at the atomic level.
Data collection and processing
The sample holder at 115x magnification. You can see a copper mesh on which a thin perforated carbon film is placed. The individual squares are called grid squares.
Viruses through the microscope
The influenza virus is only about 100 nanometers in size - by comparison, a human hair is about 1000 times thicker. The viruses are too small to be seen through a light microscope, but the scientists can still use it to see whether viruses are replicating in a cell culture. Viruses stimulate infected cells to produce viral proteins and the viral genome. Eventually, the host cells die, burst open and release new viruses. Using the light microscope, the scientists can see this process. ©NIAID/CC BY 2.0
Data collection and processing
A grid hole at about 13,000x magnification. Now you can also see contaminations as small black dots. These are aggregated proteins as well as small ice crystals.
Data collection and processing
A grid square at about 510x magnification. Here you can see the perforated carbon film. In many of these holes - called grid holes - the protein sample is stretched in a thin liquid film.
Data collection and processing
Data processing: On each captured image, protein particles are automatically detected (red circles), cut out and sorted into 2D classes. Very many detected particles together reveal more and more details (left half of the image).
Data collection and processing
Data processing: The sorted particles are now aligned three-dimensionally in space and we can calculate the electron envelope of the protein (right half of the image).
Data collection and processing
Data processing: We can then build a model of the protein into the calculated electron envelope and analyze the data at the atomic level.
Data collection and processing
The sample holder at 115x magnification. You can see a copper mesh on which a thin perforated carbon film is placed. The individual squares are called grid squares.
Data collection and processing
A view of the protein sample at 150,000x magnification. Many protein particles form a ring of eight. You can also see particles from the side that look like small garden fences.
Infected cells
Lung cells infected with SARS-CoV-2 under the fluorescence microscope: Virus particles are produced in the cytoplasm of an infected cell, which can be recognized by a green-labeled protein of the viral envelope.
Viruses through the microscope
Culture of the Vero cell line infected with influenza viruses: The infected cells die and release viruses that can infect further cells. The process results in holes in the dense cell layer. ©HZI/Bröder, Trittel
Viruses through the microscope
The influenza virus is only about 100 nanometers in size - by comparison, a human hair is about 1000 times thicker. The viruses are too small to be seen through a light microscope, but the scientists can still use it to see whether viruses are replicating in a cell culture. Viruses stimulate infected cells to produce viral proteins and the viral genome. Eventually, the host cells die, burst open and release new viruses. Using the light microscope, the scientists can see this process. ©NIAID/CC BY 2.0
Viruses through the microscope
Uninfected control culture of the Vero cell line: Cells grow in a dense, continuous cell layer. ©HZI/Bröder, Trittel
We need your consent
The virtual tour includes videos provided by YouTube. If you activate these videos, personal data may be processed and cookies may be set. The use of the virtual tour is unfortunately only possible with your consent. You can find more information on the processing of your personal data by YouTube here.