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Prof. Rolf Müller, Scientific Director of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Head of the Research Unit “Novel Antibiotics” at the German Center for Infection Research (DZIF), has been appointed to the Scientific Advisory Board of the European Partnership on One Health Antimicrobial Resistance (EUP OHAMR). HIPS is a site of the Helmholtz Centre for Infection Research (HZI) in collaboration with Saarland University.

12.01.2026

HIPS

Cryo-electron microscope image of the nuclease Cas12a3 with illustrated scissors

News

The CRISPR “gene scissors” have become an important basis for genome-editing technologies in many fields, ranging from biology and medicine to agriculture and industry. A team from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has now demonstrated that these CRISPR-Cas systems are even more versatile than previously thought. In cooperation with the Helmholtz Centre for Infection Research (HZI) in Braunschweig and Utah State University (USU) in Logan (USA), the scientists have discovered a novel CRISPR defense mechanism: Unlike known nucleases, Cas12a3 specifically destroys transfer ribonucleic acids (tRNA) that are vital for protein production to shut down infected cells. The team published its findings today in the journal Nature.

07.01.2026

HZI Campus

HIRI

News

The gene scissors CRISPR-Cas are an important tool for genome editing. However, their functionality is limited because they rely on specific sequences to operate. Their ancient ancestors, on the other hand, may have been much more versatile. Rediscovering their forgotten abilities and harnessing them for biotechnological applications is the goal of the “RGNcestry” research project led by Chase Beisel, affiliated department head at the Helmholtz Institute for RNA-based Infection Research (HIRI). The European Research Council (ERC) is funding the project with ten million euros over a period of six years.

23.12.2025

HIRI

News

Rare diseases affecting fewer than five in 10,000 people are often particularly difficult to diagnose and treat. As part of their joint funding program “zukunft.niedersachsen”, the state of Lower Saxony and the Volkswagen Foundation have now selected nine promising research projects for funding that aim to develop new diagnoses and treatments for rare diseases. Among them are two projects from the Helmholtz Centre for Infection Research (HZI). The PREDICT-CTP consortium of TWINCORE, the HZI, and Hannover Medical School (MHH) is developing a new diagnostic method for rheumatic diseases. In the StopPSC project, researchers from the HZI and MHH are developing new agents to treat primary sclerosing cholangitis, a chronically progressive inflammation of the bile ducts.

22.12.2025

TWINCORE

HZI Campus

News

Experts are increasingly turning to machine learning to predict antibiotic resistance in pathogens. With its help, resistance mechanisms can be identified based on a pathogen’s genetics. However, the results should be viewed with caution: Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg have shown that the models are often less reliable than assumed. Their findings were published in the journal PLOS Biology. They contribute to the development of more reliable tools for predicting and combating antibiotic resistance.

17.12.2025

HIRI

Teaser for the podcast with Andreas Keller

News

At first glance, biology and computer science seem like opposites. But wherever enormous amounts of data are generated from research, progress is hardly possible without digital methods. Bioinformatician Prof. Andreas Keller therefore relies on artificial intelligence. He heads the department “Clinical Bioinformatics” at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). In this episode of InFact, he talks about how AI can help us understand how beneficial and harmful bacteria communicate with each other in our bodies, how to predict when infections will cause long-term effects, and how this can be used to develop new drugs against dangerous pathogens.

16.12.2025

HIPS

HZI in the media

Fermentation und Aufreinigung, wurde ebenfalls am HZI in der Arbeitsgruppe von Prof. Marc Stadler, stellvertretender ...

06.02.2026

juraforum.de

... gehört habt: Phagen. Spoiler: Was am Helmholtz-Zentrum für Infektionsforschung (HZI) passiert, rettet im Zweifel Leben – ...

05.02.2026

Redaktionsnetzwerk Deutschland

Mattioli an: Am Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI), einem Standort des Braunschweiger Helmholtz-Zentrums für ...

04.02.2026

Universitätsklinikum Würzburg

MWK) und der VolkswagenStiftung hat das Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig das Großprojekt HUMAN ...

03.02.2026

Regional Heute

Im Programm HUMAN am Helmholtz-Zentrum für Infektionsforschung in Braunschweig entschlüsselt die nächste Generation Forschender das ...

03.02.2026

VolkswagenStiftung

Quelle: Pressemitteilung

Helmholtz-Zentrum für Infektionsforschung GmbH

03.02.2026

LaborPraxis

der Medizinischen Hochschule Hannover und des Helmholtz-Zentrums für Infektionsforschung wollen seltene rheumatische Erkrankungen des

02.02.2026

Niedersächsisches Landesjustizportal

MWK) und der VolkswagenStiftung hat das Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig das Großprojekt HUMAN ...

02.02.2026

juraforum.de

... an anderen Forschungseinrichtungen gearbeitet, beispielsweise am Helmholtz-Institut für Pharmazeutische Forschung Saarland. Was sind die ...

02.02.2026

Deutschlandfunk

waren mehrere Forschungseinrichtungen beteiligt, darunter das Helmholtz-Zentrum für Infektionsforschung . Die Ergebnisse erschienen im

02.02.2026

Münchner Merkur

Medicine (CiiM), which is a joint institution of the Helmholtz Center for Infection Research (HZI) and Hannover Medical School (MHH). Using

29.01.2026

Medical Xpress

... stumpfen ab“, erklärt Marc Brönstrup vom Helmholtz-Zentrum für Infektionsforschung in Braunschweig. Neue Antibiotika sind dringend ...

27.01.2026

Tvinfo.de

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