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Though it has been eclipsed lately by SARS-CoV-2, there is another global epidemic still threatening people: HIV/AIDS. According to UNAIDS, a United Nations initiative, some 38 million people worldwide are currently infected with HIV. Almost as many have died as a result of AIDS since the outbreak of the HIV pandemic in the 1980s. In the search for new approaches to antiviral therapies, scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the Robert Koch Institute (RKI) in Berlin have now developed a new technology that can be used to analyze and impact key stages of the HIV life cycle. Their findings were published today in the journal Nature Structural and Molecular Biology.
28.03.2022
Bakterien im Rasterelektronenmikroskop
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The bacterium Escherichia coli is found in the human intestine, and elsewhere. There it is harmless, but in certain conditions it can become a pathogen. It can cause bladder infections or even sepsis. A team of researchers led by RESIST professor Marco Galardini at TWINCORE - Centre for Experimental and Clinical Infection Research, a joint facility of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Hannover Medical School (MHH), together with colleagues from the medical faculty of the University of Paris, has now investigated whether certain genes of the bacterium are associated with the severity of the diseases caused. They have now published their findings in the journal PLOS Genetics.
24.03.2022
Chunyu Liao im Labor
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What tasks need to be done today, and which is the most urgent? People have to constantly set priorities in their daily life. Bacteria are no different: They too must prioritize when combating viruses with CRISPR. However, it was unclear how this prioritization takes place. Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a joint venture of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Julius Maximilian University (JMU) Würzburg, in cooperation with researchers from the universities of Würzburg, Freiburg and Leipzig, have now described an underlying mechanism for the first time. Their study was published in the journal Nature Microbiology.
21.03.2022
Flaggen Ukraine und EU
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The Alliance of German Science Organisations strongly supports the Federal Government’s consistent action against Russia's belligerent attack on Ukraine, which is in violation of international law.
28.02.2022
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For many diseases, the tools of medicine are reaching their limits. CRISPR technologies open new avenues for diagnostics and therapies, although the natural source of CRISPR remains largely untapped. Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a joint venture of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Julius Maximilian University (JMU) Würzburg, now demonstrate a new way to study CRISPR systems that can accelerate their conversion into tools. Their approach was published today in the journal Molecular Cell.
24.02.2022

HZI in the media

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Mdisk, stock.adobe.com

 

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EUROPE SAYS

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Eine Impfung bringt das Immunsystem in Stellung, bevor der echte Erreger kommt. Erfahren Sie, wie ...

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Apotheken Umschau

Livia V. Patrono, one of the senior authors at the Helmholtz Institute for One Health (HIOH) in Germany, said in a statement .

 

The research

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IFL Science

says Livia Patrono, a veterinarian and disease ecologist at Helmholtz Institute for One Health in Greifswald, Germany. In 2012, an infected

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Science News

... Dr. rer. nat. Jakob Wirbel vom Helmholtz-Zentrum für Infektionsforschung (Braunschweig). Das Experiment aus Stanford sei ...

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Deutsches Ärzteblatt

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