Newsroom

Antoine-Emmanuel Saliba in the laboratory.

Portrait

“What exactly happens with infections in individual cells? How, where and when does the metabolism within infected cells change? If we manage to gain a better understanding of this, we’ll be able to find starting points for tailored and effective therapies,” says Antoine-Emmanuel Saliba. He has been head of the Single-cell Analysis group at the Würzburg-based Helmholtz Institute for RNA-based Infection Research (HIRI), a branch of the Helmholtz Centre for Infection Research (HZI) headquartered in Braunschweig, Germany, for more than three years.

01.03.2021

HIRI

Elektronenmikroskopische Aufnahme einer T-Zelle

News

As part of the adaptive immune system, T cells are involved in the defence against pathogens. However, if they recognise healthy, self-structures instead of invading pathogens, autoimmune diseases can result. It is still insufficiently understood which factors are responsible for the dysregulation of the T cells. A new EU-funded programme for young researchers, coordinated by Prof. Jochen Hühn at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, aims to study tissue-resident T cells in more detail. Within the framework of the training network, 15 doctoral students will be trained at academic and non-academic institutions in ten European countries.

01.03.2021

HZI Campus

Illustration of SARS-CoV-2 virus binding (in red) to a human cell.

Story

Viruses have coexisted with mankind for a long time. The oldest genetic evidence of a viral disease shows that people already suffered from liver inflammation caused by hepatitis B viruses about 7,000 years ago. The genetic material of these viruses was found in teeth from this period, which were discovered in Saxony-Anhalt. Since then, many different viral diseases have appeared –and others, like smallpox, have disappeared forever. Newly emerging viruses, which have previously only spread in the animal kingdom, have been able to cross the species barrier and adapt to humans as new hosts. Since the end of 2019, the coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) has shown that nowadays such a virus can take over the whole world in a very short time.

01.03.2021

HZI Campus

News

23.02.2021

HZI Campus

TWINCORE

News

A group of scientists are calling for a pan-European coronavirus action plan. Given the high numbers of cases and the new variants, they say, greater efforts to contain the virus are required across the whole continent. Case numbers must be reduced as quickly as possible, as this has strong advantages for society and economy. According to the paper published in the British medical journal The Lancet, the joint action of all European countries will make each national and local effort more effective.

28.01.2021

HZI Campus

News

A huge community of microorganisms lives on and in our body – the microbiota. It is often also referred to as the microbiome, although the term microbiome actually describes the genetic information of the microbiota. Microbiome research is a relatively young field of research. Many fundamental questions are still open, and the search for possible therapeutic approaches is still in its infancy. Bioinformaticians at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, in cooperation with researchers from the Department of Biostatistics at the Harvard School of Public Health in Boston, USA, have now identified CRISPR regions of the human microbiome on the basis of the Human Microbiome Project (HMP1-II). These regions form part of the bacterial defence system against viruses and can provide an overview of past attacks. The scientists are making their extensive data resource available to microbiome research so that the interactions between viruses and bacteria can be explored further. The study, funded by the German Research Foundation (DFG), is published in the current issue of the journal Cell Host & Microbe.

20.01.2021

HZI Campus

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