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Interferons are important messenger molecules in the immune system, assisting in the fight against pathogens such as influenza viruses and probably also SARS-CoV-2. However, interferon might also be involved in immune-brain interactions unrelated to an infection and may have an influence on learning ability. This is indicated by a study with mice from the Technische Universität Braunschweig, which is published today in the scientific journal Cell Reports. The Helmholtz Centre for Infection Research in Braunschweig and TWINCORE in Hannover are also involved in the study.

20.05.2020

HZI Campus

TWINCORE

Niedersächsischer Ministerpräsident Stephan Weil und Minister Björn Thümler besuchen das Helmholtz-Zentrum für Infektionsforschung.

News

A distinguished visitor to the Helmholtz Centre for Infection Research: The Prime Minister of Lower Saxony Stephan Weil and Lower Saxony’s Minister of Science and Culture Björn Thümler visited the Helmholtz Centre for Infection Research (HZI) in Braunschweig today. The focus of the visit was on current challenges and innovative solutions, especially in the fight against SARS-CoV-2 and the future development of infection research in Lower Saxony.

08.05.2020

HZI Campus

Cas12a-Nukleasen sind leistungsstarke Werkzeuge zur Genombearbeitung, erfordern jedoch ein PAM neben jeder ausgewählten Zielsequenz. Beisels Forschungsgruppe fand heraus, dass zwei sehr ähnliche Cas12a-Nukleasen unterschiedliche PAMs erkennen können.

News

CRISPR technologies are revolutionary genome-editing tools that rely on molecular scissors called Cas nucleases to cut DNA. While these scissors can be programmed to cut virtually any sequence, that target must be flanked by a special sequence called a PAM (Protospacer Adjacent Motif). The PAM sequence is up to six nucleotides in length and can vary widely between Cas nucleases. To allow all sites of the genome to be targeted with CRISPR technologies, there is an ongoing push to collect nucleases that cover all possible PAMs. In a current study published in Nucleic Acids Research, researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg characterized technologically important Cas nucleases to determine how to expand the spectrum of target sequences. The HIRI is a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Julius Maximilian University of Würzburg.

07.05.2020

HIRI

Der Virologe Luka Cicin-Sain erforscht SARS-CoV-2-neutralisierende Antikörper, die von der Technischen Universität Braunschweig und YUMAB isoliert wurden.

News

Neutralizing antibodies are the interceptors of our immune system. They bind precisely to pathogens and prevent them from entering our cells. After an infection, the immune system needs about two weeks to produce mature antibodies. In severe cases of Covid-19, the body's immune reaction often comes too late for the patient. One option for acute treatment would therefore be to administer antibodies to the patients that are immediately effective. Recent results of the CORAT Consortia, especially from the Helmholtz Centre for Infection Research (HZI) in cooperation with the Technische Universität Braunschweig and the company YUMAB, have led to a breakthrough in the development of fully human antibodies for immune therapies.

07.05.2020

HZI Campus

Story

The Pharmacokinetics/Pharmacodynamics unit (PK/PD unit) at the Helmholtz Centre for Infection Research (HZI) in Braunschweig investigates the potential of drug candidates against pathogens, using special testing procedures. If the candidates pass these stringent preclinical tests, they stand a chance of being shortlisted for further development towards clinical testing.

06.05.2020

HZI Campus

Illustration des Coronavirus SARS-CoV-2.

News

29.04.2020

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HZI in the media

could be reintroduced at any time. Epidemiologists at the Helmholtz Center for Infection Research (HZI) have now shown that many people do

23.10.2025

MSN.com

... eingeschleppt werden könnte. Epidemiolog:innen des Helmholtz-Zentrums für Infektionsforschung (HZI) haben nun gezeigt, dass ...

23.10.2025

innovations report

this development, a research team at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in collaboration with the Swiss

22.10.2025

Phys.org

Malaria-Medikamentes ermöglichen könnte. Das HIPS ist ein Standort des Helmholtz-Zentrums für Infektionsforschung in Zusammenarbeit mit ...

22.10.2025

Verband Deutscher Biologen e.V.

(Bild: DOI: 10.1021/jacs.5c08354 / Hips / CC BY 4.0) Wissenschaftler am Hips entwickelten eine Plattform zur Produktion von Furanoliden, die effektiv gegen Bakterien und Krebszellen wirken können und vielversprechende Wirkstoffe darstellen.

21.10.2025

PROCESS

at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), in partnership with the Helmholtz Centre for Infection Research (HZI

20.10.2025

Bioengineer.org

their biological activity. HIPS is a site of the Helmholtz Center for Infection Research (HZI) in collaboration with Saarland University.

20.10.2025

Phys.org

... die Abteilung „Experimentelle Immunologie“ am Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig, lehrt als Professor an ...

17.10.2025

Deutsches Ärzteblatt

Einrichtungen als nationale assoziierte Partner: das Helmholtz-Zentrum für Infektionsforschung Braunschweig, die Universität Bayreuth, das

17.10.2025

AlphaGalileo

... diesem Ergebnis kommt ein Forschungsteam des Helmholtz-Zentrums für Infektionsforschung (HZI) in Zusammenarbeit mit der ...

14.10.2025

Deutsches Ärzteblatt

Individualisierte Infektionsmedizin, einer gemeinsamen Einrichtung des Helmholtz-Zentrums für Infektionsforschung und der MHH. Bis zuletzt

13.10.2025

Springer

Ein Grippe-Test könnte in Zukunft womöglich sehr schnell gehen: einfach ein Kaugummi kauen. Ein deutsches ...

09.10.2025

Apotheken Umschau

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