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[Translate to English:] Empfangsschild des Arabuko-Sokoke-Nationalparks
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Natural substances are an important source of active ingredients used in medicine. However, the chemical diversity of fungi in particular has not yet been sufficiently researched. The EU project Mycobiomics, coordinated by Marc Stadler, Head of the Department “Microbial Drugs” at the Helmholtz Centre for Infection Research (HZI), is investigating the biodiversity of fungi in Europe, Asia and Africa in order to identify pharmaceutically valuable secondary metabolites. In May and June 2025, project participants met in Kenya and South Africa for an expedition and a subsequent symposium.
09.07.2025
The One Health Surveillance team from HIOH receives the award for “Best Research Environment 2024”.
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Excellent conditions for research, an inspiring atmosphere and fair cooperation: for all this, the research group “One Health Surveillance” (OHS) at the Helmholtz Institute for One Health (HIOH) has been awarded the “Best Research Environment 2024” prize by the Junge Akademie. Under the leadership of Dr. Fee Zimmermann, the OHS group is establishing health and environmental observatories, so-called “One Health Exploratories”, which collect long-term and systematic data on the health of humans, animals and the environment and integrate it into a big picture. The HIOH is a site of the Helmholtz Centre for Infection Research (HZI) in Braunschweig in cooperation with the University of Greifswald, the University Medicine Greifswald and the Friedrich-Loeffler-Institut.
09.07.2025
Electron micrograph of coccal bacteria growing in chains
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Influenza viruses can trigger epigenetic changes in the alveolar epithelium, the cell layer that lines the alveoli, permanent changes in gene activity without changing the DNA itself. These changes have a lasting effect on subsequent immune responses and result in the body no longer being able to react appropriately to the bacterial pathogens in the event of a subsequent infection with pneumococci. A research team at the Helmholtz Centre for Infection Research (HZI) and the University Hospital Magdeburg (UMMD) has published new findings on the long-term consequences of an influenza A infection in a mouse model in the journal Cell Communication and Signaling.
04.07.2025
Preparing for historical specimen sampling
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From 4 to 6 June 2025, the Department “Pathogen Evolution” led by Prof. Dr. Sébastien Calvignac-Spencer at the Helmholtz Institute for One Health (HIOH) conducted a combined retreat and sampling mission at the Institute of Pathology of the University of Veterinary Medicine Vienna — a key collaboration partner for accessing and studying historical pathological specimens in veterinary medicine. HIOH is a site of the Helmholtz Centre for Infection Research (HZI). The visit focused on collecting around 60 historical tissue samples for molecular genetic analyses related to animal disease research, while also offering time for internal discussions on lab optimization, project development, and team building.
03.07.2025
Electron microscope image
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If an intestinal inhabitant such as the bacterium Escherichia coli (E. coli) becomes resistant to many antibiotics, it can cause serious health problems if it enters the bloodstream. How can such potentially dangerous multi-resistant bacteria be effectively removed from the gut? Researchers from the Helmholtz Centre for Infection Research (HZI), in collaboration with researchers from Hannover Medical School (MHH), explored this question in their latest study.
03.07.2025
Pseudocolored cells of Pseudomonas aeruginosa
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An international research team led by the Helmholtz Centre for Infection Research (HZI) has discovered a new strategy used by the human pathogen Pseudomonas aeruginosa to adapt to its host. In the journal Proceedings of the National Academy of Sciences (PNAS), the researchers demonstrate that epigenetic processes can lead to the emergence of distinct sub-populations within genetically identical bacterial populations. This heterogeneity may be a key for bacteria to establish successful infections.
02.07.2025

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