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Progress against chronic infections
“We have high hopes for this drug candidate,” explained Dr Martin Empting, who is conducting the project at the HIPS/HZI together with Prof Rolf Hartmann and Dr Thomas Hesterkamp. Unlike antibiotics, the substance does not kill the bacterium, it disrupts its ability to…
Easier decoding of unknown protein complexes
Like tiny machines, proteins in our body do hard work. Virtually all processes are performed or controlled by these highly specialised protein molecules. They transmit signals, convert energy, initiate chemical reactions or provide growth and movement. These partially…
European support for rapidly advancing vaccine development
Vaccines are one of the most successful and cost-effective public health tools for disease prevention. Their development though is time-consuming and complex, requiring a combination of specialised skills and technical capacities not readily available at a single…
Virus infections of bone marrow donors influence the outcome of transplantations
In brief: The health of the donor is just as important as that of the recipient for the success of a bone marrow transplantation. „However, our study does not focus on the impeccable health of the donor at the time of the bone marrow donation – since this is a…
Gut microbiota – Tiny helpers against Salmonella
Trillions of microorganisms colonise the surfaces of the human body as permanent, helpful companions. The composition of the so-called microbiota, i.e. the entirety of microorganisms colonising humans and animals, varies very strongly between individuals. Aside from…
Intestinal bacteria affecting the cardiovascular system
Intestinal bacteria are an important component of digestion as they convert food items into substances that can be absorbed by the body. But sometimes, the activity of these bacteria may be harmful to the human body. Certain bacterial degradation products promote the…
Novel agent inhibits communication between bacteria and renders them harmless
Antibiotic-resistant bacteria are on the advance throughout the world. This makes it even more important to develop medications to control these microorganisms. Scientists at Saar-University and at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)…
Some like it hotter
Legionella pneumophila, a bacterial pathogen known to dwell in warm water systems proliferates at temperatures between 50 and 60°C. This was shown by scientists of the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, in a study just published in…
Michael P. Manns First Clinical Director of the Helmholtz Centre for Infection Research
The Helmholtz Centre for Infection Research (HZI) in Braunschweig appointed its first Clinical Director in early October 2015. Prof Michael P. Manns from the Hannover Medical School (MHH) will take over this newly created position, in which he will coordinate and…
Recognising structures means understanding structures
Bacteria use adhesive molecules on their cellular surface to colonise a Host . The same type of molecule is also involved in the formation of highly resistant bacterial colonies, called biofilms. Since biofilms are difficult to control, they are often the basis of…