Search
Displaying results 351 to 360 of 773.
Searching for the microbial treasure
It is long known that bacterial pathogens are increasingly developing resistance to pharmaceutical agents. Nevertheless, since the 1980s, no new active ingredient has been discovered that can combat resistance in gram-negative pathogens in the long term. In addition to…
New antibiotic against river blindness and lymphatic filariasis pathogens
Infections with worms from the filarial group, also known as filariasis, can lead to river blindness and, if left untreated, to elephantiasis - a disease in which extremities become greatly enlarged due to destruction of the lymphatic vessels. The lives of those…
Lyme disease: Probability of developing the disease is genetically predisposed
If a tick is infected with the pathogen Borrelia burgdorferi s. l. (sensu lato = in the broader sense), these bacteria can be transmitted to humans through a tick bite and cause illness. Various organ systems can be affected: the skin, the nervous system or the joints.…
Member of the European Parliament Katarina Barley visits the HZI
Afterwards, several stations on the Science Campus Braunschweig-Süd were visited. The HZI is currently building a modern organoid platform under the direction of Josef Penninger, which was presented by Dr Kristin Metzdorf. Organoids are miniature models of human organs…
Antimicrobial agents of the future
The discovery of antimicrobial compounds such as conventional antibiotics has transformed medicine, allowing for the treatment of infections that were once deemed untreatable. However, the development pipeline for new agents has slowed, while the improper use of…
Tumor cells exploit the immune system for reproduction
The interdisciplinary team discovered that lung adenocarcinoma uses a sophisticated mechanism to promote the growth of cancer cells. It uses immune cells in the lung tissue and makes them work for it. Normally, these immune cells, called macrophages, are responsible for…
The Lung in a Cell-Culture Model
Following infections of lung cells through various pathogens in the culture dish: this is the goal of a new joint project of two Helmholtz research groups. The scientists are attempting to reconstruct lung cells from mice in a stable in vitro model, in order to conduct…
Dirk Heinz new Scientific Director of HZI
The Helmholtz Centre for Infection Research (Helmholtz-Zentrum für Infektionsforschung, HZI) in Braunschweig, Germany, has a new Scientific Director. The German Ministry for Education and Research (BMBF) has appointed the structural biologist Prof. Dirk Heinz with…
Molecular Tricks of the Motile Malaria Pathogen
It infects men and mosquitoes, changes its form multiple times, and moves very elegantly and rapidly through the body of its host: Plasmodium falciparum, the causative agent of malaria, shows an astonishing versatility and motility. Researchers from the Helmholtz Centre…
Hide and Seek in the Tumour
Salmonella bacteria cause several diseases – however, they have features that make them very interesting for cancer medicine: The germs migrate into tumours and lead to the death of aberrant cells. Scientists from the Helmholtz Centre for Infection Research…