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Using viruses as vaccines
Though viruses are troublesome and often even hazardous pathogens, many of them remain well-hidden and cause only mild diseases or none at all. After some modification, these viruses can be utilized to protect the body from other pathogens. Researchers make use of their…
Endogenous nano-particles acting as transporters for antibiotics
Bacteria are increasingly developing resistance to the common antibiotics – not least because of the excessive and sometimes incorrect use of these medications. Moreover, antibiotics can have unpleasant side effects as they also kill beneficial bacteria. Dr Gregor…
Hepatitis C and HIV prophylaxis from the microwave
Infections with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) among people who inject drugs (PWID) are a global health problem. For example, sharing of drug preparation equipment within this population contributes to more than 80% of newly acquired HCV…
Immune system reactions elucidated by mathematics
A body infected by the influenza virus is particularly susceptible to other pathogens. Bacteria like Streptococcus pneumoniae , i.e. the pathogen causing pneumonia, find it easy to attack an influenza-modulated immune system and to spread widely. This can even be fatal…
Hepatitis B continues to be a global health problem
Hepatitis B infections are among the most common infectious diseases worldwide. The disease can become chronic, and is one of the most important causes of severe diseases such as liver cancer. In the scope of an international study funded by the World Health…
Keeping herpes viruses dormant
The cytomegalovirus (CMV) is a herpes virus that is present, but undetected, in the majority of the human population. It causes symptoms only once the immune system of the host becomes weakened. But then it can even be fatal. For this reason, researchers are looking for…
Improving the investigation of material biofilms
Patients afflicted by cystic fibrosis, a hereditary disease, often suffer from obstinate infections by the Pseudomonas aeruginosa bacterium. This germ forms so-called biofilms in the lung. This layer of mucus allows them to defy the treatment with antibiotics.…
Phase-2 study of tuberculosis vaccine started
The inclusion of the first infant just started a clinical phase-2 study of VPM1002, a new Tuberculosis - Vaccine . This newest Tuberculosis - Vaccine in clinical development is expected to reduce the spread of the life-threatening Tuberculosis not only in endemic areas,…
Minister President Stephan Weil visits National Cohort
Lower Saxony's Minister President Stephan Weil visited the study centre of the National Cohort (NAKO) in Hannover on Thursday, 25 June 2015. NAKO is Germany's largest health study and includes 18 sites nation-wide. In the upcoming years, a total of 200,000 randomly…
Bacteria use chemical harpoons to dock onto their host
The steady increase in antibiotics resistance is one of the major global challenges facing health research. Therefore, alternatives to antibiotics are sought urgently. A potential therapeutic approach has recently been identified by scientists of the University of St.…