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HIRI researchers develop a new machine learning approach
The genome or DNA of an organism incorporates the blueprint for proteins and orchestrates the production of new cells. Aiming to combat pathogens, cure genetic diseases or achieve other positive effects, molecular biological CRISPR technologies are being used to…
Mutations in the spike-protein of the Pirola variant of SARS-CoV-2 augment infection of lung cells
A team of researchers from the German Primate Center (DPZ, Göttingen), jointly with partners at Charité (Berlin), Hannover Medical School, Helmholtz Centre for Infection Research (Braunschweig) and Friedrich-Alexander-University Erlangen-Nuremberg has now investigated…
Computer Science meets Pharmaceutical Research
Scientific experiments generally not only lead to new findings but also uncover new questions and unsolved problems. To be able to process these efficiently, both further experiments as well as computer-based tools are required. In addition to software tools, this also…
What can we expect from vaccinations – and what not?
When the COVID-19 pandemic struck in 2020, vaccines against the SARS-CoV-2 virus, which was spreading all around the world, were developed in record time. There was widespread anxiety – and the expectations of many people regarding the effect of the vaccines were just…
Structure of a central component of the human immune system revealed
An international team of researchers, including three research groups of Ludwig-Maximilians-Universität München (LMU) and Prof. Christian Sieben from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, has now visualized the 3D structure of the ASC speck…
Biodiversity of gut bacteria is associated with sexual behavior
The human body is colonized by a variety of different microorganisms such as bacteria, yeasts and fungi. All these microbial co-inhabitants - known as the microbiome or microbiota - are important for our health: For example, the microbiome in the gut supports digestion…
"The HZI could be much more self-assured in appearance and manner"
Mrs Tannapfel, how did you become aware of the HZI? Although I grew up in Lower Saxony and spent most of my legal internship in the Hannover/Hildesheim region, I did not become aware of the HZI until 2014, when the Helmholtz Institute for RNA-based Infection Research…
Vaccination with nanoparticles
To be able to vaccinate significantly more people throughout the world, it would be more useful to have vaccines that can be administered in the form of a nasal spray or a cream passing through the skin. They would not only be easier to use, but also have a crucial…