Dr. Robert Geffers

Reichardt C., Brandt S., Bernhardt A., Krause A., Lindquist J.A., Weinert S., Geffers R., Franz T., Kahlfuss S., Dudeck A., Mathew A., Rana R., ... , Isermann B., Mertens P.R. (2024)

DNA-binding protein-A promotes kidney ischemia/reperfusion injury and participates in mitochondrial function

Kidney Int.

DOI: 10.1016/j.kint.2024.05.009 HZI-Repositorium PubMed

Brandt S., Bernhardt A., Häberer S., Wolters K., Gehringer F., Reichardt C., Krause A., Geffers R., Kahlfuß S., Jeron A., Bruder D., Lindquist J.A., ... , Isermann B., Mertens P.R. (2024)

Comparative Analysis of Acute Kidney Injury Models and Related Fibrogenic Responses: Convergence on Methylation Patterns Regulated by Cold Shock Protein

Cells, 13 (5)

DOI: 10.3390/cells13050367 HZI-Repositorium PubMed

Froese N., Szaroszyk M., Galuppo P., Visker J.R., Werlein C., Korf-Klingebiel M., Berliner D., Reboll M.R., Hamouche R., Gegel S., Wang Y., Hofmann W., Tang M., Geffers R., Wende A.R., K++hnel M.P., Jonigk D.D., Hansmann G., Wollert K.C., Abel E.D., Drakos S.G., ... , Bauersachs J., Riehle C. (2024)

Hypoxia Attenuates Pressure Overload-Induced Heart Failure

Journal of the American Heart Association, 13 (3)

DOI: 10.1161/JAHA.123.033553 HZI-Repositorium PubMed

Fraccarollo D., Geffers R., Galuppo P., Bauersachs J. (2024)

Mineralocorticoid receptor promotes cardiac macrophage inflammaging

Basic Res.Cardiol.

DOI: 10.1007/s00395-024-01032-6 HZI-Repositorium PubMed

Manoharan J., Rana R., Kuenze G., Gupta D., Elwakiel A., Ambreen S., Wang H., Banerjee K., Zimmermann S., Singh K., Gupta A., Fatima S., Kretschmer S., Schaefer L., Zeng-Brouwers J., Schwab C., Al-Dabet M.M., Gadi I., Altmann H., Koch T., Poitz D.M., Baber R., Kohli S., Shahzad K., Geffers R., Lee-Kirsch M.A., Kalinke U., Meiler J., ... , Mackman N., Isermann B. (2024)

Tissue factor binds to and inhibits interferon-a[alpha] receptor 1 signaling

Immunity., 57 (1)

DOI: 10.1016/j.immuni.2023.11.017 HZI-Repositorium PubMed

Abberger H., Hose M., Ninnemann A., Menne C., Eilbrecht M., Lang K.S., Matuschewski K., Geffers R., Herz J., Buer J., ... , Westendorf A.M., Hansen W. (2023)

Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections

PLoS Pathog, 19 (11)

DOI: 10.1371/journal.ppat.1011837 PubMed

Weber C.A.M., Krönke N., Volk V., Auber B., Förster A., Trost D., Geffers R., Esmaeilzadeh M., Lalk M., Nabavi A., Samii A., Krauss J.K., Feuerhake F., Hartmann C., Wiese B., ... , Brand F., Weber R.G. (2023)

Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases e[epsilon] and d[delta] in glioma families

Acta Neuropathol.Commun., 11 (1)

DOI: 10.1186/s40478-023-01689-5 HZI-Repositorium PubMed

Werfel L., Martens H., Hennies I., Gjerstad A.C., Fröde K., Altarescu G., Banerjee S., Valenzuela Palafoll I., Geffers R., Kirschstein M., Christians A., Bjerre A., ... , Haffner D., Weber R.G. (2023)

Diagnostic Yield and Benefits of Whole Exome Sequencing in CAKUT Patients Diagnosed in the First Thousand Days of Life

Kidney Intl.Rep.

DOI: 10.1016/j.ekir.2023.08.008 HZI-Repositorium

Vogel K., Arra A., Lingel H., Bretschneider D., Prätsch F., Schanze D., Zenker M., Balk S., Bruder D., Geffers R., Hachenberg T., ... , Arens C., Brunner-Weinzierl M.C. (2023)

Bifidobacteria shape antimicrobial T-helper cell responses during infancy and adulthood

Nat.Commun., 14 (1)

DOI: 10.1038/s41467-023-41630-x HZI-Repositorium PubMed

Mohan K., Gasparoni G., Salhab A., Orlich M.M., Geffers R., Hoffmann S., Adams R.H., ... , Walter J., Nordheim A. (2023)

Age-Associated Changes in Endothelial Transcriptome and Epigenetic Landscapes Correlate With Elevated Risk of Cerebral Microbleeds

J.Am.Heart Assoc.

DOI: 10.1161/JAHA.123.031044 HZI-Repositorium PubMed

Zelenka L., Jarek M., Pägelow D., Geffers R., van Vorst K., Fulde M. (2023)

Crosstalk of Highly Purified Microglia and Astrocytes in the Frame of Toll-like Receptor (TLR)2/1 Activation

Neuroscience, 526 (August 2023)

DOI: 10.1016/j.neuroscience.2023.05.001 PubMed

Bernhardt A., Krause A., Reichardt C., Steffen H., Isermann B., Völker U., Hammer E., Geffers R., Phillipsen L., Dhjamandi K., Ahmad S., Brandt S., ... , Lindquist J.A., Mertens P.R. (2023)

Excessive sodium chloride ingestion promotes inflammation and kidney fibrosis in aging mice

Am.J.Physiol Cell Physiol

DOI: 10.1152/ajpcell.00230.2023 PubMed

Bufe S., Zimmermann A., Ravens S., Prinz I., Buitrago-Molina L.E., Geffers R., Woller N., Kühnel F., Talbot S.R., Noyan F., Manns M.P., Wedemeyer H., Hardtke-Wolenski M., ... , Jaeckel E., Davalos-Misslitz A.C. (2023)

PD-1/CTLA-4 Blockade Leads to Expansion of CD8(+)PD-1(int) TILs and Results in Tumor Remission in Experimental Liver Cancer

Liver Cancer, 12 (2)

DOI: 10.1159/000526899 HZI-Repositorium PubMed

Herppich S., Hoenicke L., Kern F., Kruse F., Smout J., Greweling-Pils M.C., Geffers R., Burton O.T., Liston A., Keller A., ... , Floess S., Huehn J. (2023)

Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation

Eur.J.Immunol.

DOI: 10.1002/eji.202250270 HZI-Repositorium PubMed

Münch P.C., Eberl C., Woelfel S., Ring D., Fritz A., Herp S., Lade I., Geffers R., Franzosa E.A., Huttenhower C., ... , McHardy A.C., Stecher B. (2023)

Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effects

Cell Host.Microbe, 31 (6)

DOI: 10.1016/j.chom.2023.05.013 PubMed

Kruse B., Buzzai A.C., Shridhar N., Braun A.D., Gellert S., Knauth K., Pozniak J., Peters J., Dittmann P., Mengoni M., van der Sluis T.C., Höhn S., Antoranz A., Krone A., Fu Y., Yu D., Essand M., Geffers R., Mougiakakos D., Kahlfuß S., Kashkar H., Gaffal E., Bosisio F.M., Bechter O., Rambow F., Marine J.C., Kastenmüller W., ... , Müller A.J., Tüting T. (2023)

CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours

Nature

DOI: 10.1038/s41586-023-06199-x HZI-Repositorium

Zhang B., Zhang Z., Koeken V.A.C.M., Kumar S., Aillaud M., Tsay H.C., Liu Z., Kraft A.R.M., Soon C.F., Odak I., Bosnjak B., Vlot A., Swertz M.A., Ohler U., Geffers R., Illig T., Hühn J., Saliba A.E., Sander L.E., Förster R., Xu C.J., Cornberg M., Schulte L.N., ... , Li Y., Deutsche C.O.V.I. (2023)

Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19

Cell Genom.

DOI: 10.1016/j.xgen.2022.100232 HZI-Repositorium PubMed

Froese N., Szaroszyk M., Korf-Klingebiel M., Koch K., Schmitto J.D., Geffers R., Hilfiker-Kleiner D., Riehle C., Wollert K.C., ... , Bauersachs J., Heineke J. (2022)

Endothelial Cell GATA2 Modulates the Cardiomyocyte Stress Response through the Regulation of Two Long Non-Coding RNAs

Biology, 11 (12)

DOI: 10.3390/biology11121736 HZI-Repositorium PubMed

Kopejtka K., Tomasch J., Kaftan D., Gardiner A.T., Bína D., Gardian Z., Bellas C., Dröge A., Geffers R., ... , Sommaruga R., Koblílek M. (2022)

A bacterium from a mountain lake harvests light using both proton-pumping xanthorhodopsins and bacteriochlorophyll-based photosystems

Proc.Natl.Acad.Sci.U.S.A., 119 (50)

DOI: 10.1073/pnas.2211018119 HZI-Repositorium PubMed

Pinel-Cabello M., Jauregui R., Jroundi F., Geffers R., Jarek M., Link A., ... , Vilchez-Vargas R., Merroun M.L. (2022)

Genetic mechanisms for Se(VI) reduction and synthesis of trigonal 1-D nanostructures in Stenotrophomonas bentonitica: Perspectives in eco-friendly nanomaterial production and bioremediation

Sci.Total Environ., 862

DOI: 10.1016/j.scitotenv.2022.160635 HZI-Repositorium PubMed

Naasner L., Froese N., Hofmann W., Galuppo P., Werlein C., Shymotiuk I., Szaroszyk M., Erschow S., Amanakis G., Bähre H., Kühnel M.P., Jonigk D.D., Geffers R., Seifert R., Ricke-Hoch M., Wende A.R., Blaner W.S., Abel E.D., ... , Bauersachs J., Riehle C. (2022)

Vitamin A Preserves Cardiac Energetic Gene Expression in a Murine Model of Diet-Induced Obesity

Am.J Physiol Heart Circ.Physiol

DOI: 10.1152/ajpheart.00514.2022 HZI-Repositorium PubMed

Kircher B., Woltemate S., Gutzki F., Schlüter D., Geffers R., ... , Bähre H., Vital M. (2022)

Predicting butyrate- and propionate-forming bacteria of gut microbiota from sequencing data

Gut Microbes, 14 (1)

DOI: 10.1080/19490976.2022.2149019 HZI-Repositorium PubMed

Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A. (2022)

Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-34487-z HZI-Repositorium PubMed

Wenzek C., Steinbach P., Wirsdörfer F., Sutter K., Boehme J.D., Geffers R., Klopfleisch R., Bruder D., Jendrossek V., Buer J., ... , Westendorf A.M., Knuschke T. (2022)

CD47 restricts antiviral function of alveolar macrophages during influenza virus infection

iScience, 25 (12)

DOI: 10.1016/j.isci.2022.105540 HZI-Repositorium PubMed

Christians A., Kesdiren E., Hennies I., Hofmann A., Trowe M.O., Brand F., Martens H., Gjerstad A.C., Gucev Z., Zirngibl M., Geffers R., Seeman T., Billing H., Bjerre A., Tasic V., Kispert A., Ure B., Haffner D., ... , Dingemann J., Weber R.G. (2022)

Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2

Hum.Genet.

DOI: 10.1007/s00439-022-02481-6 HZI-Repositorium PubMed

Chludzinski E., Klemens J., Ciurkiewicz M., Geffers R., Pöpperl P., Stoff M., Shin D.L., ... , Herrler G., Beineke A. (2022)

Phenotypic and Transcriptional Changes of Pulmonary Immune Responses in Dogs Following Canine Distemper Virus Infection

Int.J.Mol.Sci., 23 (17)

DOI: 10.3390/ijms231710019 HZI-Repositorium PubMed

Li Z., Geffers R., Jain G., Klawonn F., Kökpinar Ö., Nimtz M., ... , Schmidt-Heck W., Rinas U. (2021)

Transcriptional network analysis identifies key elements governing the recombinant protein production provoked reprogramming of carbon and energy metabolism in Escherichia coli BL21 (DE3)

Engineering Reports, 3 (9)

DOI: 10.1002/eng2.12393 HZI-Repositorium

Li S., Lu C.W., Diem E.C., Li W., Guderian M., Lindenberg M., Kruse F., Buettner M., Floess S., Winny M.R., Geffers R., Richnow H.H., Abraham W.R., ... , Grassl G.A., Lochner M. (2022)

Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5+ intestinal stem cell function

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-31725-2 HZI-Repositorium PubMed

Al-Dabet M.M., Shahzad K., Elwakiel A., Sulaj A., Kopf S., Bock F., Gadi I., Zimmermann S., Rana R., Krishnan S., Gupta D., Manoharan J., Fatima S., Nazir S., Schwab C., Baber R., Scholz M., Geffers R., Mertens P.R., Nawroth P.P., Griffin J.H., Keller M., Dockendorff C., ... , Kohli S., Isermann B. (2022)

Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-32477-9 HZI-Repositorium PubMed

Lonnemann N., Hosseini S., Ohm M., Geffers R., Hiller K., ... , Dinarello C.A., Korte M. (2022)

IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model

eLife, 11

DOI: 10.7554/eLife.75889 HZI-Repositorium PubMed

Waqas S.F., Sohail A., Nguyen A.H.H., Usman A., Ludwig T., Wegner A., Malik M.N.H., Schuchardt S., Geffers R., Winterhoff M., Merkert S., Martin U., Olmer R., ... , Lachmann N., Pessler F. (2022)

ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives

Clin.Transl.Med., 12 (7)

DOI: 10.1002/ctm2.931 HZI-Repositorium PubMed

He W., Henne A., Lauterbach M., Geißmar E., Nikolka F., Kho C., Heinz A., Dostert C., Grusdat M., Cordes T., Härm J., Goldmann O., Ewen A., Verschueren C., Blay-Cadanet J., Geffers R., Garritsen H., Kneiling M., Holm C.K., Metallo C.M., Medina E., Abdullah Z., Latz E., ... , Brenner D., Hiller K. (2022)

Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages

Nat.Metab, 4 (5)

DOI: 10.1038/s42255-022-00565-1 HZI-Repositorium PubMed

Riehle C., Sieweke J.T., Bakshi S., Ha C.M., Junker Udesen N.L., Moller-Helgestad O.K., Froese N., Berg Ravn H., Bähre H., Geffers R., Seifert R., Moller J.E., Wende A.R., ... , Bauersachs J., Schäfer A. (2022)

miRNA-200b-A Potential Biomarker Identified in a Porcine Model of Cardiogenic Shock and Mechanical Unloading

Front Cardiovasc.Med., 9

DOI: 10.3389/fcvm.2022.881067 HZI-Repositorium PubMed

Hochnadel I., Hoenicke L., Petriv N., Neubert L., Reinhard E., Hirsch T., Alfonso J.C.L., Suo H., Longerich T., Geffers R., Lichtinghagen R., Guzmán C.A., Wedemeyer H., Lenzen H., Manns M.P., ... , Bruder D., Yevsa T. (2022)

Correction: Safety and efficacy of prophylactic and therapeutic vaccine based on live-attenuated Listeria monocytogenes in hepatobiliary cancers (Oncogene, (2022), 41, 14, (2039-2053), 10.1038/s41388-022-02222-z)

Oncogene, 41 (19)

DOI: 10.1038/s41388-022-02261-6 HZI-Repositorium PubMed

Froese N., Cordero J., Abouissa A., Trogisch F.A., Grein S., Szaroszyk M., Wang Y., Gigina A., Korf-Klingebiel M., Bosnjak B., Davenport C.F., Wiehlmann L., Geffers R., Riechert E., Jürgensen L., Boileau E., Lin Y., Dieterich C., Förster R., Bauersachs J., Ola R., Dobreva G., ... , Völkers M., Heineke J. (2022)

Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication

iScience, 25 (3)

DOI: 10.1016/j.isci.2022.103965 HZI-Repositorium PubMed

Kreutzer F.P., Meinecke A., Mitzka S., Hunkler H.J., Hobuß L., Abbas N., Geffers R., Weusthoff J., Xiao K., Jonigk D.D., ... , Fiedler J., Thum T. (2022)

Development and characterization of anti-fibrotic natural compound similars with improved effectivity

Basic Res.Cardiol., 117 (1)

DOI: 10.1007/s00395-022-00919-6 HZI-Repositorium PubMed

Ebert K., Haffner I., Zwingenberger G., Keller S., Raimundez E., Geffers R., Wirtz R., Barbaria E., Hollerieth V., Arnold R., Walch A., Hasenauer J., Maier D., ... , Lordick F., Luber B. (2022)

Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies -

BMC Cancer, 22 (1)

DOI: 10.1186/s12885-022-09335-4 HZI-Repositorium PubMed

Hochnadel I., Hoenicke L., Petriv N., Neubert L., Reinhard E., Hirsch T., Alfonso J.C.L., Suo H., Longerich T., Geffers R., Lichtinghagen R., Guzmán C.A., Wedemeyer H., Lenzen H., Manns M.P., ... , Bruder D., Yevsa T. (2022)

Safety and efficacy of prophylactic and therapeutic vaccine based on live-attenuated Listeria monocytogenes in hepatobiliary cancers

Oncogene

DOI: 10.1038/s41388-022-02222-z HZI-Repositorium PubMed

Schäfer F., Görner P., Woltemate S., Brandenberger C., Geffers R., Ziesing S., ... , Schlüter D., Vital M. (2022)

The Resistance Mechanism Governs Physiological Adaptation of Escherichia coli to Growth With Sublethal Concentrations of Carbapenem

Front.Microbiol., 12

DOI: 10.3389/fmicb.2021.812544 HZI-Repositorium PubMed

Krone A., Fu Y., Schreiber S., Kotrba J., Borde L., Nötzold A., Thurm C., Negele J., Franz T., Stegemann-Koniszewski S., Schreiber J., Garbers C., Shukla A., Geffers R., Schraven B., Reinhold D., Dudeck A., Reinhold A., ... , Müller A.J., Kahlfuss S. (2022)

Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc

Sci.Rep., 12 (1)

DOI: 10.1038/s41598-022-04827-6 HZI-Repositorium PubMed

Radmanesh H., Liu D., Geffers R., Shandiz F.H., Sadr-Nabavi A., Hillemanns P., ... , Park-Simon T.W., Dörk T. (2022)

Exome sequencing identifies RASSF1 and KLK3 germline variants in an Iranian multiple-case breast cancer family

Eur.J.Med.Genet., 65 (3)

DOI: 10.1016/j.ejmg.2022.104425 PubMed

Szaroszyk M., Kattih B., Martin-Garrido A., Trogisch F.A., Dittrich G.M., Grund A., Abouissa A., Derlin K., Meier M., Holler T., Korf-Klingebiel M., Völker K., Garfias Macedo T., Pablo Tortola C., Boschmann M., Huang N., Froese N., Zwadlo C., Malek Mohammadi M., Luo X., Wagner M., Cordero J., Geffers R., Batkai S., Thum T., Bork N., Nikolaev V.O., Müller O.J., Katus H.A., El-Armouche A., Kraft T., Springer J., Dobreva G., Wollert K.C., Fielitz J., von Haehling S., Kuhn M., ... , Bauersachs J., Heineke J. (2022)

Skeletal muscle derived Musclin protects the heart during pathological overload

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-021-27634-5 HZI-Repositorium PubMed

Wendisch D., Dietrich O., Mari T., von Stillfried S., Ibarra I.L., Mittermaier M., Mache C., Chua R.L., Knoll R., Timm S., Brumhard S., Krammer T., Zauber H., Hiller A.L., Pascual-Reguant A., Mothes R., Bülow R.D., Schulze J., Leipold A.M., Djudjaj S., Erhard F., Geffers R., Pott F., Kazmierski J., Radke J., Pergantis P., Baßler K., Conrad C., Aschenbrenner A.C., Sawitzki B., Landthaler M., Wyler E., Horst D., Hippenstiel S., Hocke A., Heppner F.L., Uhrig A., Garcia C., Machleidt F., Herold S., Elezkurtaj S., Thibeault C., Witzenrath M., Cochain C., Suttorp N., Drosten C., Goffinet C., Kurth F., Schultze J.L., Radbruch H., Ochs M., Eils R., Müller-Redetzky H., Hauser A.E., Luecken M.D., Theis F.J., Conrad C., Wolff T., Boor P., Selbach M., Saliba A.E., ... , Sander L.E., Deutsche C.O.V.I. (2021)

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Cell, 184 (26)

DOI: 10.1016/j.cell.2021.11.033 HZI-Repositorium PubMed

Waindok P., Janecek-Erfurth E., Lindenwald D.L., Wilk E., Schughart K., ... , Geffers R., Strube C. (2022)

Toxocara canis-and Toxocara cati-Induced Neurotoxocarosis Is Associated with Comprehensive Brain Transcriptomic Alterations

Microorg., 10 (1)

DOI: 10.3390/microorganisms10010177 HZI-Repositorium PubMed

Sohail A., Iqbal A.A., Sahini N., Chen F., Tantawy M., Waqas F., Winterhoff M., Ebensen T., Schultz K., Geffers R., Schughart K., Preusse M., Shehata M., Bähre H., Pils M.C., Guzmán C.A., Mostafa A., Pleschka S., Falk C., ... , Michelucci A., Pessler F. (2022)

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

PLoS Pathog., 18 (1)

DOI: 10.1371/journal.ppat.1010219 HZI-Repositorium PubMed

Quentmeier H., Geffers R., Hauer V., Nagel S., Pommerenke C., Uphoff C.C., ... , Zaborski M., Drexler H.G. (2022)

Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma

Sci.Rep., 12 (1)

DOI: 10.1038/s41598-022-04916-6 HZI-Repositorium PubMed

Malik M.N.H., Waqas S.F.H., Zeitvogel J., Cheng J., Geffers R., Gouda Z.A., Elsaman A.M., Radwan A.R., Schefzyk M., Braubach P., Auber B., Olmer R., Müsken M., Roesner L.M., Gerold G., Schuchardt S., Merkert S., Martin U., Meissner F., ... , Werfel T., Pessler F. (2021)

Congenital deficiency reveals critical role of ISG15 in skin homeostasis

J.Clin.Invest

DOI: 10.1172/JCI141573 HZI-Repositorium PubMed

Dietrich O., Heinz A., Goldmann O., Geffers R., Beineke A., Hiller K., ... , Saliba A.E., Medina E. (2021)

Dysregulated Immunometabolism Is Associated with the Generation of Myeloid-Derived Suppressor Cells in Staphylococcus aureus Chronic Infection

J.Innate.Immun.

DOI: 10.1159/000519306 HZI-Repositorium PubMed

Preuß E.B., Schubert S., Werlein C., Stark H., Braubach P., Höfer A., Plucinski E.K.J., Shah H.R., Geffers R., Sewald K., Braun A., ... , Jonigk D.D., Kühnel M.P. (2021)

The challenge of long-term cultivation of human precision-cut lung slices

Am.J.Pathol.

DOI: 10.1016/j.ajpath.2021.10.020 HZI-Repositorium PubMed

Kunzke T., Hölzl F.T., Prade V.M., Buck A., Huber K., Feuchtinger A., Ebert K., Zwingenberger G., Geffers R., Hauck S.M., Haffner I., Luber B., ... , Lordick F., Walch A. (2021)

Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer

Clin.Transl.Med., 11 (9)

DOI: 10.1002/ctm2.547 HZI-Repositorium PubMed

Ramli S.R., Bunk B., Spröer C., Geffers R., Jarek M., Bhuju S., Goris M., ... , Mustakim S., Pessler F. (2021)

Complete genome sequencing of leptospira interrogans isolates from malaysia reveals massive genome rearrangement but high conservation of virulence-associated genes

Pathogens, 10 (9)

DOI: 10.3390/pathogens10091198 HZI-Repositorium PubMed

Schütte K., Schulz C., Vilchez-Vargas R., Vasapolli R., Palm F., Simon B., Schomburg D., Lux A., Geffers R., Pieper D.H., ... , Link A., Malfertheiner P. (2021)

Impact of healthy aging on active bacterial assemblages throughout the gastrointestinal tract

Gut Microbes, 13 (1)

DOI: 10.1080/19490976.2021.1966261 HZI-Repositorium PubMed

Adamczyk A., Pastille E., Kehrmann J., Vu V.P., Geffers R., Wasmer M.H., Kasper S., Schuler M., Lange C.M., Muggli B., Rau T.T., Klein D., Hansen W., Krebs P., ... , Buer J., Westendorf A.M. (2021)

GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer

Cancer Res., 81 (11)

DOI: 10.1158/0008-5472.CAN-20-2133 HZI-Repositorium PubMed

Mohammadi M.M., Abouissa A., Azizah I., Xie Y., Cordero J., Shirvani A., Gigina A., Engelhardt M., Trogisch F.A., Geffers R., Dobreva G., ... , Bauersachs J., Heineke J. (2019)

Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation

JCI Insight, 4 (16)

DOI: 10.1172/jci.insight.128336 HZI-Repositorium PubMed

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Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis

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Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently

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Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction

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Antiviral potential of human IFN-a[alpha] subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities

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Possible Role and Therapeutic Target of PDGF-D Signalling in Colorectal Cancer

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Pathog.Dis., 73 (1)

Janecek E., Wilk E., Schughart K., Geffers R., Strube C. (2015)

Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes

Int.J.Parasitol., 45 (7)

Ohrnberger S., Thavamani A., Braeuning A., Lipka D.B., Kirilov M., Geffers R., Authenrieth S.E., Römer M., Zell A., Bonin M., Schwarz M., Schütz G., Schirmacher P., Plass C., ... , Longerich T., Nordheim A. (2015)

Dysregulated serum response factor triggers formation of hepatocellular carcinoma

Hepatology, 61 (3)

DOI: 10.1002/hep.27539 HZI-Repositorium PubMed

Shin D.L., Pandey A.K., Ziebarth J.D., Mulligan M.K., Williams R.W., Geffers R., Hatesuer B., ... , Schughart K., Wilk E. (2015)

Segregation of a spontaneous Klrd1 (CD94) mutation in DBA/2 mouse substrains

G3 Genes Genome Genet., 5 (2)

DOI: 10.1534/g3.114.015164 HZI-Repositorium PubMed

Strehmel J., Neidig A., Nusser M., Geffers Robert, Brenner-Weiss G., Overhage J. (2014)

The sensor kinase PA4398 modulates swarming motility and biofilm formation in Pseudomonas aeruginosa PA14

Applied in Environmental Microbiology, 81 (4)

Elgohary N., Pellegrino R., Neumann O., Elzawahry H.M., Saber M.M., Zeeneldin A.A., Geffers Robert, Ehemann V., Schemmer P., ... , Schirmacher P., Longerich T. (2014)

Protumorigenic role of Timeless in hepatocellular carcinoma

International Journal of Oncology, 46 (2)

DOI: 10.3892/ijo.2014.2751 HZI-Repositorium PubMed

Vazquez C.L., Lerner T.R., Kasmapour B., Pei G., Gronow Achim, Bianco M.V., Blanco F.C., Bleck C.K., Geffers Robert, Bigi F., ... , Abraham Wolf-Rainer, Gutierrez Maximiliano G. (2014)

Experimental selection of long-term intracellular mycobacteria

Cell Microbiology, 16

DOI: 10.1111/cmi.12303 HZI-Repositorium PubMed

Rudalska R., Dauch D., Longerich T., McJunkin K., Wuestefeld T., Kang T.W., Hohmeyer A., Pesic M., Leibold J., von Thun A., Schirmacher P., Zuber J., Weiss K.H., Powers S., Malek N.P., Eilers M., Sipos B., Lowe S.W., Geffers Robert, ... , Laufer S., Zender L. (2014)

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Nature medicine

Winkler J., Ori A., Holzer K., Sticht C., Dauch D., Eiteneuer E.M., Pinna F., Geffers Robert, Ehemann V., Andres-Pons A., Breuhahn K., Longerich T., Bermejo J.L., Gretz N., Zender L., Schirmacher P., ... , Beck M., Singer S. (2014)

Prosurvival function of the cellular apoptosis susceptibility/importin-?1 transport cycle is repressed by p53 in liver cancer

Hepatology, 60 (3)

Marhenke S., Buitrago-Molina L.E., Endig J., Orlik J., Schweitzer N., Klett S., Longerich T., Geffers Robert, Munoz A.S., Dorrell C., Katz S.F., Lechel A., Weng H., Krech T., Lehmann U., Dooley S., Rudolph K.L., ... , Manns M.P., Vogel A. (2014)

P21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury

GUT, 63 (9)

Lim C.H., Voedisch S., Wahl B., Rouf S.F., Geffers Robert, ... , Rhen M., Pabst O. (2014)

Independent Bottlenecks Characterize Colonization of Systemic Compartments and Gut Lymphoid Tissue by Salmonella

PLoS Pathogens, 10 (7)

Kehrmann J., Tatura R., Zeschnigk M., Probst-Kepper Michael, Geffers Robert, ... , Steinmann J., Buer J. (2014)

Impact of 5-aza-2'-deoxycytidine and epigallocatechin-3-gallate for induction of human regulatory T cells

Immunology, 142 (3)

DOI: 10.1111/imm.12261 HZI-Repositorium PubMed

Yun H., Damm F., Yap D., Schwarzer A., Chaturvedi A., Jyotsana N., Lubbert M., Bullinger L., Dohner K., Geffers Robert, Aparicio S., Humphries R.K., ... , Ganser A., Heuser M. (2014)

Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia

Haematologica, 99 (9)

DOI: 10.3324/haematol.2013.101386 HZI-Repositorium PubMed

Habig C., Geffers Robert, Distl O. (2014)

A replication study for genome-wide gene expression levels in two layer lines elucidates differentially expressed genes of pathways involved in bone remodeling and immune responsiveness

PLoS ONE, 9 (6)

DOI: 10.1371/journal.pone.0098350 HZI-Repositorium PubMed

Gutschner T., Hammerle M., Pazaitis N., Bley N., Fiskin E., Uckelmann H., Heim A., Grobeta M., Hofmann N., Geffers Robert, Skawran B., Longerich T., Breuhahn K., Schirmacher P., Muhleck B., ... , Huttelmaier S., Diederichs S. (2014)

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma

Hepatology, 59 (5)

Sagar V., Bergmann René, Nerlich A., McMillan D.J., Nitsche-Schmitz D.Patric, Fulde M., Talay Susanne, Geffers Robert, Hoe N., Kumar R., Rohde M., ... , Chakraborti A., Chhatwal Gursharan S. (2014)

Differences in virulence repertoire and cell invasive potential of Group A Streptococcus emm1-2 in comparison to emm1 genotype

International Journal of Medical Microbiology, 304 (5-6)

Jauregui Ruy, Rodelas B., Geffers Robert, Boon N., Pieper Dietmar H., Vilchez-Vargas Ramiro (2014)

Draft Genome Sequence of the Naphthalene Degrader Herbaspirillum sp. Strain RV1423

Genome Announcement, 2 (2)

Dag F., Dolken L., Holzki J., Drabig A., Weingartner A., Schwerk J., Lienenklaus S., Conte I., Geffers R., Davenport C., Rand U., Köster M., Weiss S., Adler B., Wirth D., Messerle M., ... , Hauser H., Cicin-Sain L. (2014)

Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency

PLoS Pathogens, 10 (2)

DOI: 10.1371/journal.ppat.1003962 HZI-Repositorium PubMed

Strempel N., Neidig A., Nusser M., Geffers Robert, Vieillard J., Lesouhaitier O., ... , Brenner-Weiss G., Overhage J. (2013)

Human host defense peptide LL-37 Stimulates virulence factor production and adaptive resistance in Pseudomonas aeruginosa

PLoS ONE, 8 (12)

DOI: 10.1371/journal.pone.0082240 HZI-Repositorium PubMed

Hämmerle M., Gutschner T., Uckelmann H., Ozgur S., Fiskin E., Gross M., Skawran B., Geffers Robert, Longerich T., Breuhahn K., Schirmacher P., ... , Stoecklin G., Diederichs S. (2013)

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)

Hepatology, 58 (5)

DOI: 10.1002/hep.26537 HZI-Repositorium PubMed

Volkmann I., Kumarswamy R., Pfaff N., Fiedler J., Dangwal S., Holzmann A., Batkai S., Geffers Robert, Lother A., ... , Hein L., Thum T. (2013)

MicroRNA-Mediated Epigenetic Silencing of Sirtuin1 Contributes to Impaired Angiogenic Responses1

Circulation Research, 113 (8)

Buitrago-Molina L.E., Marhenke S., Longerich T., Sharma A.D., Boukouris A.E., Geffers Robert, Guigas Bruno, ... , Manns M.P., Vogel A. (2013)

The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice

Hepatology, 58 (3)

DOI: 10.1002/hep.26412 HZI-Repositorium PubMed

Hasemeier B., Geffers Robert, Bartels S., Schlegelberger B., Kreipe H., Lehmann U. (2013)

Archival bone marrow trephines are suitable for high-throughput mutation analysis using next generation sequencing technology

Haematologica, 98 (9)

DOI: 10.3324/haematol.2013.091652 HZI-Repositorium PubMed

Jeron A., Hansen W., Ewert F., Buer J., Geffers R., Bruder D. (2012)

ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells

BMC GENOMICS, 13 (1)

DOI: 10.1186/1471-2164-13-705 HZI-Repositorium

Zender S., Nickeleit I., Wuestefeld T., Sörensen I., Dauch D., Bozko P., El-Khatib M., Geffers Robert, Bektas H., Manns M., Gossler A., Wilkens L., Plentz R., ... , Zender L., Malek N. (2013)

A critical role for notch signaling in the formation of cholangiocellular carcinomas

Cancer Cell, 23 (6)

Shepelkova G., Pommerenke C., Alberts R., Geffers Robert, Evstifeev V., Apt A., ... , Schughart Klaus, Wilk E. (2013)

Analysis of the lung transcriptome in Mycobacterium tuberculosis-infected mice reveals major differences in immune response pathways between TB-susceptible and resistant hosts

Tuberculosis (Edinb.), 93 (2)

Sundarasetty B.S., Singh V.K., Salguero G., Geffers Robert, Rickmann M., Macke L., Borchers S., Figueiredo C., Schambach A., Gullberg U., Provasi E., Bonini C., Ganser A., ... , Woelfel T., Stripecke R. (2013)

Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia

Human gene therapy, 24 (2)

DOI: 10.1089/hum.2012.128 HZI-Repositorium PubMed

Quentmeier H., Amini R.M., Berglund M., Dirks W.G., Ehrentraut S., Geffers Robert, MacLeod R.A., Nagel S., Romani J., Scherr M., ... , Zaborski M., Drexler H.G. (2013)

U-2932: two clones in one cell line, a tool for the study of clonal evolution

Leukemia, 27 (5)

Vilchez-Vargas Ramiro, Geffers Robert, Suarez-Diez Maria, Conte Ianina, Waliczek Agnes, Kaser Vanessa S., Kralova M., ... , Junca H., Pieper Dietmar H. (2013)

Analysis of the microbial gene landscape and transcriptome for aromatic pollutants and alkane degradation using a novel internally calibrated microarray system

Environmental Microbiology, 15 (4)

DOI: 10.1126/scitranslmed.3009925 HZI-Repositorium PubMed

Toker A., Engelbert D., Garg G., Polansky J.K., Floess S., Miyao T., Baron U., Düber S., Geffers R., Giehr P., Schallenberg S., Kretschmer K., Olek S., Walter J., Weiss S., Hori S., ... , Hamann A., Hühn J. (2013)

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus

Journal of Immunology, 190 (7)

Wuestefeld T., Pesic M., Rudalska R., Dauch D., Longerich T., Kang T.W., Yevsa T., Heinzmann F., Hoenicke L., Hohmeyer A., Potapova A., Rittelmeier I., Jarek Michael, Geffers Robert, Scharfe Maren, Klawonn Frank, Schirmacher P., Malek N.P., Ott M., Nordheim A., Vogel A., ... , Manns M.P., Zender L. (2013)

A direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration

Cell, 153 (2)

Kindler E., Jonsdottir H.R., Muth D., Hamming O.J., Hartmann R., Rodriguez R., Geffers Robert., Fouchier R.A., Drosten C., Muller M.A., ... , Dijkman R., Thiel V. (2013)

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

MBio, 4 (1)

DOI: 10.1128/mBio.00611-12 HZI-Repositorium PubMed

Ehrentraut S., Nagel S., Scherr M.E., Schneider B., Quentmeier H., Geffers Robert, Kaufmann M., Meyer C., Prochorec-Sobieszek M., Ketterling R.P., Knudson R.A., Feldman A.L., Kadin M.E., ... , Drexler H.G., MacLeod R.A. (2013)

t(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 via STAT5

PLoS ONE, 8 (1)

DOI: 10.1371/journal.pone.0053767 HZI-Repositorium PubMed

He F., Chen H., Probst-Kepper Michael, Geffers Robert, Eifes S., Del Sol A., Schughart Klaus, ... , Zeng A.P., Balling R. (2012)

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells

Molecular Systems Biology, 8

DOI: 10.1038/msb.2012.56 HZI-Repositorium PubMed

Ukena S.N., Geffers Robert, Buchholz S., Stadler M., Franzke A. (2012)

Biomarkers for acute and chronic graft-versus-host disease in regulatory T cells

Transplant Immunology, 27 (4)

DOI: 10.1016/j.trim.2012.07.003

Christgen M., Noskowicz M., Heil C., Schipper E., Christgen H., Geffers Robert, ... , Kreipe H., Lehmann U. (2012)

IPH-926 lobular breast cancer cells harbor a p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes

Laboratory Investigation, 92 (11)

Hamisch D., Randewig D., Schliesky S., Brautigam A., Weber A.P., Geffers Robert, Herschbach C., Rennenberg H., ... , Mendel R.R., Hansch R. (2012)

Impact of SO(2) on Arabidopsis thaliana transcriptome in wildtype and sulfite oxidase knockout plants analyzed by RNA deep sequencing

New Phytologist, 196 (4)

DOI: 10.1111/j.1469-8137.2012.04331.x HZI-Repositorium PubMed

Neumann O., Kesselmeier M., Geffers Robert, Pellegrino R., Radlwimmer B., Hoffmann K., Ehemann V., Schemmer P., Schirmacher P., ... , Lorenzo Bermejo J., Longerich T. (2012)

Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors

Hepatology, 56 (5)

DOI: 10.1002/hep.25870 HZI-Repositorium PubMed

Habig C., Geffers Robert, Distl O. (2012)

Differential gene expression from genome-wide microarray analyses distinguishes lohmann selected leghorn and lohmann brown layers

PLoS ONE, 7 (10)

DOI: 10.1371/journal.pone.0046787 HZI-Repositorium PubMed

Pommerenke C., Wilk E., Srivastava B., Schulze A., Novoselova N., ... , Geffers Robert, Schughart Klaus (2012)

Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses

PLoS ONE, 7 (7)

DOI: 10.1371/journal.pone.0041169 HZI-Repositorium PubMed

Nagel S., Ehrentraut S., Tomasch J., Lienenklaus S., Schneider B., Geffers Robert, Meyer C., Kaufmann M., ... , Drexler H.G., MacLeod R.A. (2012)

Transcriptional Activation of Prostate Specific Homeobox Gene NKX3-1 in Subsets of T-Cell Lymphoblastic Leukemia (T-ALL)

PLoS ONE, 7 (7)

DOI: 10.1371/journal.pone.0040747 HZI-Repositorium PubMed

Abel S., Luckheide N., Westendorf A.M., Geffers R., Roers A., Müller W., Sparwasser Tim*, Matuschewski K., ... , Buer J., Hansen W. (2012)

Strong Impact of CD4+Foxp3+ Regulatory T Cells and Limited Effect of T Cell-Derived IL-10 on Pathogen Clearance during Plasmodium yoelii Infection

Journal of Immunology, 188 (11)

DOI: 10.4049/jimmunol.1102223 PubMed

Block J., Breitsprecher D., Kuhn S., Winterhoff M., Kage F., Geffers R., Duwe P., Rohn J.L., Baum B., Brakebusch C., Geyer M., Stradal T.E., ... , Faix J., Rottner K. (2012)

FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

Current biology, 22 (11)

DOI: 10.1016/j.cub.2012.03.064 HZI-Repositorium PubMed

Bendrat K., Stang A., Georgiev G., Geffers Robert, Haase B., Schutze K., Mogilarov D., ... , Branscheid D., Niendorf A. (2012)

A compartment-specific transcriptome analysis reveals survival-relevant marker genes in the stroma fraction of squamous non-small cell lung cancer

Journal of Biophotonics, 5 (4)

Alberts R., Chen H., Pommerenke C., Smit A.B., Spijker S., Williams R.W., Geffers Robert*, ... , Bruder Dunja*, Schughart Klaus* (2011)

Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease1

BMC GENOMICS, 12

DOI: 10.1186/1471-2164-12-610 HZI-Repositorium

Dötsch A., Eckweiler D., Schniederjans M., Zimmermann A., Jensen V., Scharfe M., ... , Geffers Robert, Häußler Susanne (2012)

The Pseudomonas aeruginosa

PLoS ONE, 7 (2)

DOI: 10.1371/journal.pone.0031092 HZI-Repositorium PubMed

Gohler A.K., Kokpinar O., Schmidt-Heck W., Geffers R., Guthke R., Rinas U., Schuster S., ... , Jahreis K., Kaleta C. (2011)

More than just a metabolic regulator - elucidation and validation of new targets of PdhR in Escherichia coli1

BMC Systems Biology, 5

DOI: 10.1186/1752-0509-5-197 HZI-Repositorium PubMed

Boppana S., Scheglov A., Geffers Robert, Tarabykin V. (2012)

Cellular retinaldehyde-binding protein (CRALBP) is a direct downstream target of transcription factor Pax6

Biochimica et biophysica acta, 1820 (2)

DOI: 10.1016/j.bbagen.2011.09.015 HZI-Repositorium PubMed

Schneider B., Nagel S., Ehrentraut S., Kaufmann M., Meyer C., Geffers Robert, ... , Drexler H.G., MacLeod R.A. (2012)

Neoplastic MiR-17 approximately 92 deregulation at a dna fragility motif (SIDD)

Genes, Chromosomes and Cancer, 51 (3)

DOI: 10.1002/gcc.20946 HZI-Repositorium PubMed

Krech T., Scheuerer E., Geffers Robert, Kreipe H., Lehmann U., Christgen M. (2012)

ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells

Cancer Letters, 315 (2)

Ziegler C., Goldmann O., Hobeika E., Geffers Robert*, Peters G., Medina Eva* (2011)

The dynamics of T cells during persistent Staphylococcus aureus infection: from antigen-reactivity to in vivo anergy

EMBO Molecular Medicine, 3 (11)

Svensson J., Jenmalm M.C., Matussek A., Geffers Robert*, Berg G., Ernerudh J. (2011)

Macrophages at the fetal-maternal interface express markers of alternative activation and are induced by M-CSF and IL-10

Journal of Immunology, 187 (7)

Ukena S.N., Velaga S., Geffers Robert*, Grosse J., Baron U., Buchholz S., Stadler M., Bruder Dunja*, ... , Ganser A., Franzke A. (2011)

Human regulatory T cells in allogeneic stem cell transplantation

Blood, 118 (13)

TrehanPati N., Sukriti S., Geffers R., Hissar S., Riese P., Toepfer T., ... , Guzmán C.A., Sarin S.K. (2011)

Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase

Journal of Clinical Immunology, 31 (3)

DOI: 10.1007/s10875-010-9506-210.1007/s10875-010-9506-2 HZI-Repositorium PubMed

Fleissner D., Frede A., Knott M., Knuschke T., Geffers R., Hansen W., Dobos G., Langhorst J., ... , Buer J., Westendorf A.M. (2011)

Generation and function of immunosuppressive human and murine CD8(+) T cells by transforming growth factor-b[beta] and retinoic acid

Immunology, 134 (1)

DOI: 10.1111/j.1365-2567.2011.03469.x HZI-Repositorium PubMed

Frank S., Klockgether J., Hagendorf P., Geffers Robert*, Schock U., Pohl T., ... , Davenport C.F., Tummler B. (2011)

Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray transcriptomics

Environmental Microbiology, 13 (5)

Froese N., Kattih B., Breitbart A., Grund A., Geffers R., Molkentin J.D., Kispert A., Wollert K.C., ... , Drexler H., Heineke J. (2011)

GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor b[beta]/activin receptor-like kinase 5 signaling

Journal of Biological Chemistry, 286 (7)

DOI: 10.1074/jbc.M110.176925 HZI-Repositorium PubMed

Schenk U., Frascoli M., Proietti M., Geffers Robert*, Traggiai E., Buer J., Ricordi C., ... , Westendorf A.M., Grassi F. (2011)

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

Science Signaling, 4 (162)

DOI: 10.1126/scisignal.2001270 HZI-Repositorium PubMed

do Valle T.Z., Billecocq A., Guillemot L., Alberts R., Gommet C., Geffers Robert*, Calabrese K., Schughart Klaus*, Bouloy M., ... , Montagutelli X., Panthier J.J. (2010)

A new mouse model reveals a critical role for host innate immunity in resistance to Rift Valley fever

Journal of Immunology, 185 (10)

DOI: 10.4049/jimmunol.1000949 HZI-Repositorium PubMed

Gekara N.O., Zietara N., Geffers Robert*, Weiss Siegfried* (2010)

Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O

Journal of Infectious Diseases, 202 (11)

DOI: 10.1086/657145 HZI-Repositorium PubMed

Fleissner D., Hansen W., Geffers Robert*, Buer J., Westendorf A.M. (2010)

Local induction of immunosuppressive CD8+ T cells in the gut-associated lymphoid tissues

PLoS ONE, 5 (10)

DOI: 10.1371/journal.pone.0015373 HZI-Repositorium PubMed

Lahl K., Mayer C.T., Bopp T., Hühn Jochen*, Loddenkemper C., Eberl G., Wirnsberger G., Dornmair K., Geffers Robert*, Schmitt E., ... , Buer J., Sparwasser T. (2009)

Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice

Journal of Immunology, 183 (9)

Leonhardt J., Kuebler J.F., Turowski C., Tschernig T., Geffers Robert*, Petersen C. (2010)

Susceptibility to experimental biliary atresia linked to different hepatic gene expression profiles in two mouse strains

Hepatology Research, 40 (2)

DOI: 10.1111/j.1872-034X.2009.00577.x HZI-Repositorium PubMed

Micklinghoff J.C., Schmidt M., Geffers Robert*, Tegge Werner*, Bange F.C. (2010)

Analysis of expression and regulatory functions of the ribosome-binding protein TypA in Mycobacterium tuberculosis under stress conditions

Archives of Microbiology, 192 (6)

Hansen W., Westendorf A.M., Toepfer T., Mauel S., Geffers Robert*, ... , Gruber A.D., Buer J. (2010)

Inflammation in vivo is modulated by GPR83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cells

Genes and Immunity, 11 (4)

Dietrich N., Rohde Manfred*, Geffers Robert*, Kroger A., Hauser Hansjörg*, ... , Weiss Siegfried*, Gekara N.O. (2010)

Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteria

Proceeding of the National Academy of Sciences of the United States of America, 107 (19)

Stegmann K.A., Björkström N.K., Liermann H., Ciesek S., Riese P., Wiegand J., Hadem J., Suneetha P.V., Jaroszewicz J., Wang C., Schlaphoff V., Fytili P., Cornberg M., Manns M.P., Geffers R., Pietschmann T., Guzmán C.A., ... , Ljunggren H.-G., Wedemeyer H. (2010)

Interf alpha-induced TRAIL on human NK cells is associated with control of hepatitis C virus infection

Gastroenterology, 138 (5)

DOI: 10.1053/j.gastro.2010.01.051 PubMed

Macke L., Garritsen H.S., Meyring W., Hannig H., Pagelow U., Wormann B., Piechaczek C., Geffers Robert*, Rohde Manfred*, ... , Lindenmaier Werner*, Dittmar Kurt E.* (2010)

Evaluating maturation and genetic modification of human dendritic cells in a new polyolefin cell culture bag system

Transfusion, 50 (4)

Garritsen H.S., Macke L., Meyring W., Hannig H., Pagelow U., Wormann B., Geffers Robert*, ... , Dittmar Kurt E.*, Lindenmaier Werner* (2010)

Efficient generation of clinical-grade genetically modified dendritic cells for presentation of multiple tumor-associated proteins

Transfusion, 50 (4)

Christgen M., Geffers Robert*, Ballmaier M., Christgen H., Poczkaj J., Krech T., ... , Kreipe H., Lehmann U. (2010)

Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells

Journal of Biological Chemistry, 285 (9)

Malm S., Tiffert Y., Micklinghoff J., Schultze S., Joost I., Weber I., Horst S., Ackermann B., Schmidt M., Wohlleben W., Ehlers S., Geffers R., ... , Reuther J., Bange F.C. (2009)

The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis

Microbiology, 155 (Pt 4)

Probst-Kepper M., Geffers R., Kroger A., Viegas N., Erck C., Hecht H.-J., Lünsdorf H., Roubin R., Moharregh-Khiabani D., Wagner K., Ocklenburg F., Jeron A., Garritsen H., Arstila T.P., Kekalainen E., Balling R., Hauser H., ... , Buer J., Weiss S. (2009)

GARP: a key receptor controlling FOXP3 in human regulatory T cells

Journal of Cellular and Molecular Medicine, 13 (9)

Alberts R., Srivastava B., Wu H., Viegas N., Geffers Robert*, Klawonn F., Novoselova N., Zaverucha do V, ... , Panthier J.J., Schughart Klaus* (2010)

Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection

Microbes and Infection, 12 (4)

DOI: 10.1016/j.micinf.2010.01.008 HZI-Repositorium PubMed

Micklinghoff J.C., Breitinger K.J., Schmidt M., Geffers Robert*, Eikmanns B.J., Bange F.C. (2009)

Role of the transcriptional regulator RamB (Rv0465c) in the control of the glyoxylate cycle in Mycobacterium tuberculosis

Journal of Bacteriology, 191 (23)

Klebensberger J., Birkenmaier A., Geffers Robert*, Kjelleberg S., Philipp B. (2009)

SiaA and SiaD are essential for inducing autoaggregation as a specific response to detergent stress in Pseudomonas aeruginosa

Environmental Microbiology, 11 (12)

DOI: 10.1111/j.1462-2920.2009.02012.x HZI-Repositorium PubMed

Stark L., Matussek A., Strindhall J., Geffers Robert*, Buer J., Kihlstrom E., Monnecke S., ... , Lofgren S., Lindgren P.E. (2009)

Staphylococcus aureus isolates from blood and anterior nares induce similar innate immune responses in endothelial cells

APMIS, 117 (11)

Njau F., Geffers Robert*, Thalmann J., Haller H., Wagner A.D. (2009)

Restriction of Chlamydia pneumoniae replication in human dendritic cell by activation of indoleamine 2,3-dioxygenase

Microbes and Infection, 11 (13)

DOI: 10.1016/j.micinf.2009.07.006 PubMed

Garritsen H.S.P., Xiu-Cheng Fan A., Lenz D., Hannig H., Zhong X.Y., Geffers Robert*, Lindenmaier Werner*, ... , Dittmar Kurt E.J.*, Wörmann B. (2009)

Molecular diagnostics in transfusion medicine: In capillary, on a chip, in silico, or in flight?

Transfusion Medicine and Hemotherapy, 36 (3)

DOI: 10.1159/000217719 HZI-Repositorium

Jeron A., Pfoertner S., Bruder Dunja*, Geffers Robert*, Hammerer P., Hofmann R., ... , Buer J., Schrader A.J. (2009)

Frequency and Gene Expression Profile of Regulatory T Cells in Renal Cell Carcinoma

Tumor Biology, 30 (3)

Pati N.T., Geffers R., Sukriti Hissar S., Riese P., Toepfer T., Buer J., ... , Guzmán C.A., Sarin S.K. (2009)

Gene expression signatures of peripheral CD4+ T cells clearly discriminate between patients with acute and chronic hepatitis B viral infection

Hepatology, 49 (3)

Dötsch A., Pommerenke C., Bredenbruch F., Geffers Robert*, Häußler Susanne* (2009)

Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome

BMC GENOMICS, 10

DOI: 10.1186/1471-2164-10-29 HZI-Repositorium PubMed

Srivastava B., Blazejewska P., Hessmann M., Bruder D., Geffers Robert*, Mauel S., ... , Gruber A.D., Schughart Klaus* (2009)

Host genetic background strongly influences the response to influenza a virus infections

PLoS ONE, 4 (3)

DOI: 10.1371/journal.pone.0004857 HZI-Repositorium PubMed

Ukena S.N., Koenecke C., Geffers Robert*, Fuehner T., Welte T., Ganser A., ... , Buer J., Franzke A. (2009)

T helper type 2 differentiation is associated with induction of antibacterial defense mechanisms in blood lymphocytes of patients with sarcoidosis

Immunological Investigations, 38 (1)

Quentmeier H., Geffers Robert*, Jost E., MacLeod R.A., Nagel S., Rohrs S., Romani J., Scherr M., ... , Zaborski M., Drexler H.G. (2008)

SOCS2: inhibitor of JAK2V617F-mediated signal transduction

Leukemia, 22 (12)

Bitterle E., Hofer T., Karg E., Ferron G.A., Schroeppel A., Tippe A., Geffers Robert*, Kreyling W.G., ... , Maier K.L., Heyder J. (2004)

A new in-vitro evice for exposure of epithelial cells to airborne ultrafine elemental carbon particles at the air-liquid interface

Journal of Aerosol Science, 35 ((Suppl. 2))

DOI: 10.1016/j.jaerosci.2004.06.064 PubMed

Block J., Stradal T.E.B., Hanisch J., Geffers R., Kostler S.A., Urban E., Small J.V., ... , Rottner K., Faix J. (2008)

Filopodia formation induced by active mDia2/Drf3

Journal of Microscopy, 231 (3)

DOI: 10.1111/j.1365-2818.2008.02063.x HZI-Repositorium PubMed

Basler T., Geffers Robert*, Weiss Siegfried*, Valentin-Weigand P., Goethe R. (2008)

Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: Evidence for enhanced pathogenicity of

Immunobiology, 213 (9-10)

Marhenke S., Lamle J., Buitrago-Molina L.E., Canon J.M., Geffers Robert*, Finegold M., Sporn M., Yamamoto M., Manns M.P., ... , Grompe M., Vogel A. (2008)

Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development

Hepatology, 48 (2)

Depke M., Fusch G., Domanska G., Geffers Robert*, Volker U., ... , Schuett C., Kiank C. (2008)

Hypermetabolic syndrome as a consequence of repeated psychological stress in mice

Endocrinology, 149 (6)

DOI: 10.1210/en.2008-0038 HZI-Repositorium PubMed

Nickeleit I., Zender S., Sasse Florenz*, Geffers Robert*, Brandes G., Sorensen I., Steinmetz Heinrich*, Kubicka S., Carlomagno T., Menche D., Gutgemann I., Buer J., Gossler A., Manns M.P., Kalesse Markus*, ... , Frank Ronald*, Malek N.P. (2008)

Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition

Cancer Cell, 14 (1)

Lamle J., Marhenke S., Borlak J., von Wasielewski R., Eriksson C.J., Geffers Robert*, Manns M.P., ... , Yamamoto M., Vogel A. (2008)

Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury

Gastroenterology, 134 (4)

Seifert O., Bayat A., Geffers Robert*, Dienus K., Buer J., ... , Lofgren S., Matussek A. (2008)

Identification of unique gene expression patterns within different lesional sites of keloids

Wound Repair and Regeneration, 16 (2)

Sztajer Helena*, Lemme A., Vilchez R., Schulz S., Geffers Robert*, Yip C.Y.Y., Levesque C.M., ... , Cvitkovitch D.G., Wagner-Döbler Irene* (2008)

Autoinducer-2-regulated genes in Streptococcus mutans

Journal of Bacteriology, 190 (1)

DOI: 10.1128/JB.01086-07 HZI-Repositorium PubMed

Hansen W., Westendorf A.M., Reinwald S., Bruder Dunja*, Deppenmeier S., Gröbe Lothar*, Probst-Kepper Michael*, Gruber A.D., ... , Geffers Robert*, Buer Jan* (2007)

Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3 -

Journal of Immunology, 179

Zheng P., Sun J., Geffers Robert*, Zeng An-Ping* (2007)

Functional characterization of the gene PA2384 in large-scale gene regulation in response to iron starvation in Pseudomonas aeruginosa

Journal of Biotechnology, 132 (4)

Müller S., Geffers Robert*, Gunther S. (2007)

Analysis of gene expression in Lassa virus-infected HuH-7 cells

Journal of General Virology, 88

Goldmann O., von Kockritz-Blickwede M., Holtje C., Chhatwal G.S., Geffers R., Medina E. (2007)

Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes

Infection and Immunity, 75 (8)

DOI: 10.1128/IAI.00181-07 HZI-Repositorium PubMed

Fleige A., Alberti S., Gröbe L., Frischmann U., Geffers R., Müller W., ... , Nordheim A., Schippers A. (2007)

Serum response factor contributes selectively to lymphocyte development

The Journal of Biological Chemistry, 282 (33)

DOI: 10.1074/jbc.M703119200 HZI-Repositorium PubMed

Davies M.R., McMillan D.J., Baiko R.G., Barroso V., Geffers Robert*, ... , Sriprakash K.S., Chhatwal Gursharan S*. (2007)

Virulence profiling of Streptococcus dysgalactiae

Clinical Infectious Diseases, 44 (11)

DOI: 10.1086/516780 HZI-Repositorium

McMillan D.J., Geffers Robert*, Buer Jan*, Vlaminckx B.J.M., Sriprakash K.S., Chhatwal Gursharan S*. (2007)

Variations in the distribution of genes encoding virulence and extracellular proteins in group A streptococcus are largely restricted to eleven genomic loci

Microbes and Infection, 9 (3)

Bohn G., Allroth A., Brandes G., Thiel J., Glocker E., Schäffer A.A., Rathinam C., Taub N., Teis D., Zeidler C., Dewey R.A., Geffers Robert*, Buer Jan*, Huber L.A., Welte K., ... , Grimbacher B., Klein C. (2007)

A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14

Nature medicine, 13 (1)

Bohn G., Allroth A., Thiel J., Schaffer A.A., Brandes G., Glocker E., Teis D., Taub N., Zeidler C., Geffers Robert*, Buer Jan*, Huber L.A., Welte K., ... , Grimbacher B., Klein C. (2005)

A variant of congenital neutropenia is caused by a 3'-UTR mutation in the gene encoding the endosomal adaptor protein p14 (MAPBPIP)

Blood, 106

Franzke A., Koenecke C., Geffers Robert*, Piao W., Hunger J.K., ... , Ganser A., Buer Jan* (2006)

Classical Hodgkin's lymphoma: Molecular evidence for specific alterations in circulating T lymphocytes

Tumor Biology, 27 (6)

Franzke A., Geffers Robert*, Hunger J.K., Pförtner Susanne*, Piao W., Ivanyi P., Grosse J., Probst-Kepper M., ... , Ganser A., Buer Jan* (2006)

Identification of novel regulators in T-cell differentiation of aplastic anemia patients

BMC GENOMICS, 7

DOI: 10.1186/1471-2164-7-263 HZI-Repositorium PubMed

Pfoertner S., Jeron A., Probst-Kepper M., Guzmán C.A., Hansen W., Westendorf A.M., Toepfer T., Schrader A.J., Franzke A., ... , Buer J., Geffers R. (2006)

Signatures of human regulatory T cells: an encounter with old friends and new players

Genome Biology, 7

DOI: 10.1186/gb-2006-7-7-r54 HZI-Repositorium PubMed

Fritzsching B., Oberle N., Pauly E., Geffers Robert*, Buer Jan*, Poschl J., Krammer P., ... , Linderkamp O., Suri-Payer E. (2006)

Naive regulatory T cells: a novel subpopulation defined by resistance towards CD95L-mediated cell death

Blood

DOI: 10.1182/blood-2006-02-005660

Timmerbeul I., Garrett-Engele C.M., Kossatz U., Chen X., Firpo E., Grunwald V., Kamino K., Wilkens L., Lehmann U., Buer Jan*, Geffers Robert*, Kubicka S., Manns M.P., Porter P.L., ... , Roberts J.M., Malek N.P. (2006)

Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer

Proceedings of National Academy of Sciences USA, 103

DOI: 10.1073/pnas.0606316103 HZI-Repositorium PubMed

Nalca Y., Jänsch Lothar*, Bredenbruch F., Geffers Robert*, Buer Jan*, Häußler Susanne* (2006)

Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 50

DOI: 10.1128/AAC.50.5.1680-1688.2006 HZI-Repositorium PubMed

Bredenbruch F., Geffers Robert*, Nimtz Manfred*, Buer Jan*, Häußler Susanne* (2006)

The Pseudomonas aeruginosa

Environmental Microbiology, 8

DOI: 10.1111/j.1462-2920.2006.01025.x HZI-Repositorium PubMed

McMillan D.J., Beiko R.G., Geffers Robert*, Buer Jahn*, Schouls L.M., Vlaminckx B.J., Wannet W.J., ... , Sriprakash K.S., Chhatwal Gursharan S*. (2006)

Genes for the majority of group a streptococcal virulence factors and extracellular surface proteins do not confer an increased propensity to cause invasive disease

Clinical Infectious Diseases, 43

Ocklenburg F., Moharregh-Khiabani D., Geffers Robert*, Janke V., Pfoertner S., Garritsen H., Groebe L., Klempnauer J., Dittmar Kurt E.J.*, Weiss Siegfried*, ... , Buer Jan*, Probst-Kepper M. (2006)

UBD, a down-stream element of Foxp3, leads to the identification of LGALS3, a new marker of human regulatory T cells

Laboratory Investigation, 86

De Buhr M., Mähler M., Geffers Robert*, Hansen W., Westendorf Astrid M.*, Lauber J., Buer Jan*, Akira S., Schlegelberger B., ... , Hedrich H.J., Bleich A. (2006)

Cd14, Gbp1, and Pla2g2a: 3 major candidate genes for experimental IBD identified by combining QTL and microarray analyses

Physiological Genomics, 25

DOI: 10.1152/physiolgenomics.00022.2005 PubMed

Helming L., Böse J., Ehrchen J., Schiebe S., Frahm T., Geffers R., Probst-Kepper M., ... , Balling R., Lengeling A. (2005)

1a[alpha],25-Dihydroxyvitamin D3 is a potent suppressor of interferon g[gamma]-mediated macrophage activation

Blood, 106

DOI: 10.1182/blood-2005-03-1029 HZI-Repositorium PubMed

Goldmann O., Lengeling A., Böse J., Blöcker H., Geffers R., ... , Chhatwal G.S., Medina E. (2005)

The role of the major histocompatibility complex on resistance to Group A Streptococci in mice

Journal of Immunology, 175

Rathinam C., Geffers R., Yücel R., Buer J., Welte K., ... , Möröy T., Klein C. (2005)

The transcriptional repressor Gfi1 controls STAT3-dependent dentritic cell development and function

Immunity, 22

Salunkhe P., Smart C.H., Morgan J.A., Panagea S., Walshaw M.J., Hart C.A., Geffers R., ... , Tummler B., Winstanley C. (2005)

A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance

Journal of Bacteriology, 187

Quentmeier H., Tonelli R., Geffers R., Pession A., Uphoff C.C., Drexler H.G. (2005)

Expression of BEX1 in acute myeloid leukemia with MLL rearrangements

Leukemia, 19

Czuchra A., Wu X., Meyer H., Van Hengel J., Schroeder T., Geffers R., ... , Rottner K., Brakebusch C. (2005)

Cdc42 is not essential for filopodium formation, directed migration, cell polarization and mitosis in fibroblastoid cells

Molecular Biology of the Cell, 16 (10)

DOI: 10.1091/mbc.E05-01-0061. HZI-Repositorium

Ukena S., Westendorf A.M., Hansen W., Rohde M., Geffers R., Coldeway S., Suerbaum S., ... , Buer J., Gunzer F. (2005)

The host response to the probiotic Escherichia coli

BMC Medical Genetics, 6

DOI: 10.1186/1471-2350-6-43 HZI-Repositorium PubMed

Pfoertner S., Goelden U., Hansen W., Toepfer T., Geffers R., Ukena S.N., von Knobloch R., Hofmann R., ... , Buer J., Schrader A.J. (2005)

Cellular retinoic acid binding protein I: expression and functional influence in renal cell carcinoma

Tumor Biology, 6

Matussek A., Strindhall J., Stark L., Buer J., Geffers R., Rohde M., Kihlstroem E., ... , Lindgren P.-E., Loefgren S. (2005)

Infection of human endothelial cells with Staphylococcus aureus induces transcription of genes encoding an innate immunity response

Scandinavian Journal of Immunology, 61

Westendorf A.M., Templin M., Geffers R., Deppenmeier S., Gruber A.D., Probst-Kepper M., Hansen W., Liblau R.S., Gunzer F., ... , Bruder D., Buer J. (2005)

CD4+ T cell mediated instinal immunity: chronic inflammation versus immune regulation

GUT, 54

Satyanarayana A., Geffers R., Manns M.P., Buer J., Rudolph K.L. (2004)

Gene expression profile at the G1/S transition of liver regeneration after partial hepatectomy in mice

Cell Cycle, 3 (11)

Bruder D., Westendorf A.M., Geffers R., Gruber A.D., Gereke M., ... , Enelow R.I., Buer J. (2004)

CD4 T cell mediated lung disease: steady state between pathological and tolerogenic immune reactions

American Journal of Respiratory and Critical Care Medicine, 170

Saravanamuthu S.S., Von Götz F., Salunkhe P., Choshavendan R., Geffers R., Buer J., ... , Tümmler B., Steinmetz I. (2004)

Evidence for polyadenylated mRNA in Pseudomonas aeruginosa

Journal of Bacteriology, 186

Bohn E., Müller S., Lauber J., Geffers R., Speer N., Speer C., Krejci J., Manncke B., Buer J., ... , Zell A., Autenrieth I.B. (2004)

Gene expression patterns of epithelial cells modulated by pathogenicity factors of Yersinia enterocolitica

Cellular Microbiology, 6 (2)

Matys V., Fricke E., Geffers R., Gößling E., Haubrock M., Hehl R., Hornischer K., Karas D., Kel A.E., Kel-Margoulis E.V., Kloos D.U., Land S., Lewicki-Potapov B., Michael H., Münch R., Reuter I., Rotert S., Saxel H., Scheer M., ... , Thiele S., Wingender E. (2003)

TRANSFAC®: transcriptional regulation, from patterns to profiles

Nucleic Acids Research, 31

HZI-Repositorium PubMed

Wingender E., Chen X., Fricke E., Geffers R., Hehl R., Liebich I., Krull M., Matys V., Michael H., Ohnhauser R., Pruss M., Schacherer F., ... , Thiele S., Urbach S. (2001)

The TRANSFAC system on gene expression regulation

Nucleic Acids Research, 29 (1)

Geffers R., Sell S., Cerff R., Hehl R. (2001)

The TATA box and a Myb binding site are essential for anaerobic expression of a maize GapC4 minimal promoter in tobacco

Biochimica et Biophysica Acta - Gene Structure and Expression, 1521 (1-3)

Geffers R., Cerff R., Hehl R. (2000)

Anaerobiosis-specific interaction of tobacco nuclear factors with cis-regulatory sequences in the maize GapC4 promoter

Plant Molecular Biology, 43 (1)

Dr. Robert Geffers

Dr. Robert Geffers

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