Prof. Dr. Andrea Kröger

Prof. Dr. Andrea Kröger
Forschungsgruppenleiterin
+49 531 6181-5060

Andrea Kröger studierte Biologie an der Technischen Universität in Braunschweig. Ab 1995 arbeitete sie in der Arbeitsgruppe von Dr. Hansjörg Hauser am Institut für Genregulation und Differenzierung des Helmholtz-Zentrums für Infektionsforschung ein und promovierte 1999. Während ihrer Doktorarbeit beschäftigte sie sich mit der Charakterisierung des Transkriptionsfaktors IRF-1 in Maus-Tumormodellen und der Entwicklung von Screening-Zelllinien zur Identifizierung kleiner Moleküle für die IRF-1-Induktion.

In ihrer Postdoktorandenzeit in der Gruppe von Dr. Hansjörg Hauser beschäftigte sie sich mit der Stimulation von Immunantworten bei Entzündungen und Infektionen. Seit 2010 erforscht Andrea Kröger als Projektleiterin des Projekts "Interferone in der Immunabwehr“ die Mechanismen, die das Interferon-System zur Bekämpfung von Infektionen und zur Beeinflussung von protektiven Immunantworten nutzt.

Seit 2012 leitet Andrea Kröger die Forschungsgruppe "Angeborene Immunität und Infektion" am HZI. Im Dezember 2014 hat sie ihre Habilitation für Zellbiologie an der Technischen Universität Braunschweig abgeschlossen. Seit Juni 2015 hat Andrea Kröger eine Professur für Molekulare Mikrobiologie an der Otto-von-Guericke-Universität Magdeburg.

Publikationen
Passarella S., Kethiswaran S., Brandes K., Tsai I.C., Cebulski K., Kröger A., ... , Dieterich D.C., Landgraf P. (2024)
Alteration of cGAS-STING signaling pathway components in the mouse cortex and hippocampus during healthy brain aging
Frontiers in Aging Neuroscience, 16
DOI: 10.3389/fnagi.2024.1429005 HZI-Repositorium PubMed
Hollstein M.M., Dierks S., Schön M.P., Bergmann A., Abratis A., Eidizadeh A., Kaltenbach S., Schanz J., Groß U., Leha A., Kröger A., Andag R., Zautner A.E., Fischer A., ... , Erpenbeck L., Schnelle M. (2023)
Humoral and cellular immune responses in fully vaccinated individuals with or without SARS-CoV-2 breakthrough infection: Results from the CoV-ADAPT cohort
J.Med.Virol., 95 (10)
DOI: 10.1002/jmv.29122 HZI-Repositorium PubMed
Weichert L., Düsedau H.P., Fritzsch D., Schreier S., Scharf A., Grashoff M., Cebulski K., Michaelsen-Preusse K., Erck C., Lienenklaus S., ... , Dunay I.R., Kröger A. (2023)
Astrocytes evoke a robust IRF7-independent type I interferon response upon neurotropic viral infection
J.Neuroinflamm., 20 (1)
DOI: 10.1186/s12974-023-02892-w HZI-Repositorium PubMed
Jakob J., Kröger A., Klawonn F., Bruder D., J+ñnsch L. (2023)
Translatome analyses by bio-orthogonal non-canonical amino acid labeling reveal that MR1-activated MAIT cells induce an M1 phenotype and antiviral programming in antigen-presenting monocytes
Front.Immunol., 14
DOI: 10.3389/fimmu.2023.1091837 HZI-Repositorium PubMed
Schwerk J., Kemper L., Bussey K.A., Lienenklaus S., Weiss S., Cicin-Sain L., Kröger A., Kalinke U., Collins C.M., Speck S.H., Messerle M., Wirth D., Brinkmann M.M., ... , Hauser H., Köster M. (2022)
Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo
Pathogens, 11 (12)
DOI: 10.3390/pathogens11121554 HZI-Repositorium PubMed
Münsterkötter L., Hollstein M.M., Hahn A., Kröger A., Schnelle M., Erpenbeck L., Groß U., ... , Frickmann H., Zautner A.E. (2022)
Comparison of the Anti-SARS-CoV-2 Surrogate Neutralization Assays by TECOmedical and DiaPROPH-Med with Samples from Vaccinated and Infected Individuals
Viruses, 14 (2)
DOI: 10.3390/v14020315 HZI-Repositorium PubMed
Chaudhry M.Z., Eschke K., Hoffmann M., Grashoff M., Abassi L., Kim Y., Brunotte L., Ludwig S., Kröger A., Klawonn F., ... , Pöhlmann S.H., Cicin-Sain L. (2022)
Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases
J.Virol.
DOI: 10.1128/jvi.02186-21 HZI-Repositorium PubMed
Laudenbach B.T., Krey K., Emslander Q., Andersen L.L., Reim A., Scaturro P., Mundigl S., Dächert C., Manske K., Moser M., Ludwig J., Wohlleber D., Kröger A., ... , Binder M., Pichlmair A. (2021)
NUDT2 initiates viral RNA degradation by removal of 5'-phosphates
Nat.Commun., 12 (1)
DOI: 10.1038/s41467-021-27239-y HZI-Repositorium PubMed
Düsedau H.P., Steffen J., Figueiredo C.A., Boehme J.D., Schultz K., Erck C., Korte M., Faber-Zuschratter H., Smalla K.H., Dieterich D., Kröger A., ... , Bruder D., Dunay I.R. (2021)
Influenza A Virus (H1N1) Infection Induces Microglial Activation and Temporal Dysbalance in Glutamatergic Synaptic Transmission
MBio., 12 (5)
DOI: 10.1128/mBio.01776-21 HZI-Repositorium PubMed
Rox K., Heyner M., Krull J., Harmrolfs K., Rinne V., Hokkanen J., Perez Vilaro G., Díez J., Müller R., Kröger A., ... , Sugiyama Y., Brönstrup M. (2021)
Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Treatment of Dengue Infections Applied to the Broad Spectrum Antiviral Soraphen A
ACS Pharm.Transl.Sci., 4 (5)
DOI: 10.1021/acsptsci.1c00078 HZI-Repositorium PubMed
Koschel J., Nishanth G., Just S., Harit K., Kröger A., Deckert M., ... , Naumann M., Schlüter D. (2021)
Correction: OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation (Cell Death & Differentiation, (2021), 10.1038/s41418-021-00752-9)
Cell Death and Differentiation
DOI: 10.1038/s41418-021-00819-7 HZI-Repositorium
Petry M., Palus M., Leitzen E., Mitterreiter J.G., Huang B., Kröger A., Verjans G.M.G.M., Baumgärtner W., Rimmelzwaan G.F., Ruzek D., ... , Osterhaus A., Prajeeth C.K. (2021)
Immunity to TBEV related flaviviruses with reduced pathogenicity protects mice from disease but not from TBEV entry into the CNS
Vaccines, 9 (3)
DOI: 10.3390/vaccines9030196 HZI-Repositorium PubMed
Bertoglio F., Meier D., Langreder N., Steinke S., Rand U., Simonelli L., Heine P.A., Ballmann R., Schneider K.T., Roth K.D.R., Ruschig M., Riese P., Eschke K., Kim Y., Schäckermann D., Pedotti M., Kuhn P., Zock-Emmenthal S., Wöhrle J., Kilb N., Herz T., Becker M., Grasshoff M., Wenzel E.V., Russo G., Kröger A., Brunotte L., Ludwig S., Fühner V., Krämer S.D., Dübel S., Varani L., Roth G., Cicin-Sain L., ... , Schubert M., Hust M. (2021)
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
Nat.Commun., 12 (1)
DOI: 10.1038/s41467-021-21609-2 HZI-Repositorium PubMed
Koschel J., Nishanth G., Just S., Harit K., Kröger A., Deckert M., ... , Naumann M., Schlüter D. (2021)
OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation
Cell Death.Differ.
DOI: 10.1038/s41418-021-00752-9 HZI-Repositorium PubMed
Schreier S., Cebulski K., Kröger A. (2021)
Contact-dependent transmission of Langat and tick-borne encephalitis virus in type I interferon receptor-1 deficient mice
J.Virol., 95 (8)
DOI: 10.1128/JVI.02039-20 HZI-Repositorium PubMed
Lindqvist R., Rosendal E., Weber E., Asghar N., Schreier S., Lenman A., Johansson M., Dobler G., Bestehorn M., ... , Kröger A., Överby A.K. (2020)
The envelope protein of tick-borne encephalitis virus influences neuron entry, pathogenicity, and vaccine protection
J Neuroinflammation, 17 (1)
DOI: 10.1186/s12974-020-01943-w HZI-Repositorium PubMed
Cornelius A.D.A., Hosseini S., Schreier S., Fritzsch D., Weichert L., Michaelsen-Preusse K., ... , Fendt M., Kröger A. (2020)
Langat virus infection affects hippocampal neuron morphology and function in mice without disease signs
J Neuroinflammation, 17 (1)
DOI: 10.1186/s12974-020-01951-w HZI-Repositorium PubMed
Wedekind A., Fritzsch D., Kröger A. (2020)
Add on the next level-the time point of the type I IFN response orchestrates the immune response
Cell.Mol.Immunol, 17 (8)
DOI: 10.1038/s41423-020-0442-7 HZI-Repositorium PubMed
Prochnow H., Rox K., Birudukota N.V.S., Weichert L., Hotop S.K., Klahn P., Mohr K., Franz S., Banda D.H., Blockus S., Schreiber J., Haid S., Oeyen M., Martinez J.P., Süssmuth R.D., Wink J., Meyerhans A., Goffinet C., Messerle M., Schulz T.F., Kröger A., Schols D., ... , Pietschmann T., Brönstrup M. (2020)
Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis
J.Virol., 94 (2)
DOI: 10.1128/JVI.01471-19 HZI-Repositorium PubMed
Ring S., Eggers L., Behrends J., Wutkowski A., Schwudke D., Kröger A., Hierweger A.M., Hölscher C., ... , Gabriel G., Schneider B.E. (2019)
Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation
JCI Insight, 4 (10)
DOI: 10.1172/jci.insight.126533 HZI-Repositorium PubMed
Büssow K., Themann P., Luu S., Pentrowski P., Harting C., Majewski M., Vollmer V., Köster M., Grashoff M., Zawatzky R., van den Heuvel J., ... , Kröger A., Böldicke T. (2019)
ER intrabody-mediated inhibition of interferon a secretion by mouse macrophages and dendritic cells
PLoS ONE, 14 (4)
DOI: 10.1371/journal.pone.0215062 HZI-Repositorium PubMed
Heyner M., Schreier S., Kröger A. (2019)
The brain-immune cells axis controls tissue specific immunopathology
Cell Mol.Immunol., 16 (2)
DOI: 10.1038/s41423-018-0176-y HZI-Repositorium PubMed
Blume J., Zietara N., Witzlau K., Liu Y., Sanchez O.O., Puchalka J., Winter S.J., Kunze-Schumacher H., Saran N., Duber S., Roy B., Weiss S., Klein C., Wurst W., ... , Lyszkiewicz M., Kröger A. (2019)
miR-191 modulates B-cell development and targets transcription factors E2A, Foxp1, and Egr1
Eur.J.Immunol., 49 (1)
DOI: 10.1002/eji.201847660
Kurhade C., Schreier S., Lee Y.P., Zegenhagen L., Hjertqvist M., Dobler G., ... , Kröger A., Överby A.K. (2018)
Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice
Emerg.Infect.Dis., 24 (9)
DOI: 10.3201/eid2409.171825 HZI-Repositorium PubMed
Stegemann-Koniszewski S., Behrens S., Boehme J.D., Hochnadel I., Riese P., Guzmán C.A., Kröger A., Schreiber J., ... , Gunzer M., Bruder D. (2018)
Respiratory influenza A virus infection triggers local and systemic natural killer cell activation via toll-like receptor 7
Front.Immunol., 9 (FEB)
DOI: 10.3389/fimmu.2018.00245 HZI-Repositorium PubMed
Somplatzki S., Muhlenhoff M., Kröger A., Gerardy-Schahn R., Böldicke T. (2017)
Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells
BMC Biotechnol., 17 (1)
DOI: 10.1186/s12896-017-0360-7 HZI-Repositorium PubMed
Asghar N., Lee Y.P., Nilsson E., Lindqvist R., Melik W., Kröger A., ... , Overby A.K., Johansson M. (2016)
The role of the poly(A) tract in the replication and virulence of tick-borne encephalitis virus
Sci Rep., 6
DOI: 10.1038/srep39265 HZI-Repositorium PubMed
Lindqvist R., Mundt F., Gilthorpe J.D., Wolfel S., Gekara N.O., ... , Kröger A., Overby A.K. (2016)
Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects
J Neuroinflammation., 13 (1)
DOI: 10.1186/s12974-016-0748-7] HZI-Repositorium PubMed
Stegemann-Koniszewski S., Jeron A., Gereke M., Geffers R., Kroger A., ... , Gunzer M., Bruder D. (2016)
Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals
MBio., 7 (3)
DOI: 10.1128/mBio.00276-16 HZI-Repositorium PubMed
Andzinski L., Spanier J., Kasnitz N., Kroger A., Jin L., Brinkmann M.M., Kalinke U., Weiss S., ... , Jablonska J., Lienenklaus S. (2016)
Growing tumors induce a local STING dependent type I IFN response in dendritic cells
Int.J Cancer, 139 (6)
DOI: 10.1002/ijc.30159 HZI-Repositorium PubMed
Nocera D.A., Roselli E., Araya P., Nunez N.G., Lienenklaus S., Jablonska J., Weiss S., Gatti G., Brinkmann M.M., Kroger A., ... , Moron G., Maccioni M. (2016)
In Vivo Visualizing the IFN-b[beta] Response Required for Tumor Growth Control in a Therapeutic Model of Polyadenylic-Polyuridylic Acid Administration
J Immunol., 196 (6)
DOI: 10.4049/jimmunol.1501044 PubMed
Zegenhagen L., Kurhade C., Koniszewski N., Overby A.K., Kröger A. (2016)
Brain heterogeneity leads to differential innate immune responses and modulates pathogenesis of viral infections
Cytokine Growth Factor Rev., 30
DOI: 10.1016/j.cytogfr.2016.03.006
Castiglia V., Piersigilli A., Ebner F., Janos M., Goldmann O., Dambock U., Kroger A., Weiss S., Knapp S., Jamieson A.M., Kirschning C., Kalinke U., Strobl B., Muller M., Stoiber D., ... , Lienenklaus S., Kovarik P. (2016)
Type I Interferon Signaling Prevents IL-1b[beta]-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue
Cell Host.Microbe, 19 (3)
DOI: 10.1016/j.chom.2016.02.003 HZI-Repositorium PubMed
Kurhade C., Zegenhagen L., Weber E., Nair S., Michaelsen-Preusse K., Spanier J., Gekara N.O., ... , Kroger A., Overby A.K. (2016)
Type I Interferon response in olfactory bulb, the site of tick-borne flavivirus accumulation, is primarily regulated by IPS-1
J Neuroinflammation., 13 (1)
DOI: 10.1186/s12974-016-0487-9 HZI-Repositorium PubMed
Marandu T.F., Oduro J.D., Borkner L., Dekhtiarenko I., Uhrlaub J., Drabig A., Kroger A., ... , Nikolich-Zugich J., Cicin-Sain L. (2015)
Immune protection against virus challenge in aging mice is not affected by latent herpesviral infections
J Virol., 89
DOI: 10.1128/JVI.01989-15 HZI-Repositorium PubMed
Härtlova A., Erttmann S.F., Raffi F.A.M., Schmalz A.M., Resch U., Anugula S., Lienenklaus S., Nilsson L.M., Kröger A., Nilsson J.A., Ek T., ... , Weiss S., Gekara N.O. (2015)
DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
Immunity, 42 (2)
DOI: 10.1016/j.immuni.2015.01.012 HZI-Repositorium PubMed
Wu Ching-Fang, Andzinski Lisa, Kasnitz Nadine, Kröger Andrea, Klawonn Frank, Lienenklaus Stefan, ... , Weiss Siegfried, Jablonska Jadwiga (2015)
The lack of type I interferon induces neutrophil-mediated pre-metastatic niche formation in the mouse lung
International Journal of Cancer, 137
Weber E., Finsterbusch Katja, Lindquist R., Nair S., Lienenklaus S., Gekara N.O.*, Janik D., Weiss S., Kalinke U., ... , Overby A.K., Kröger A. (2014)
Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local anti-viral response
Journal of Virology, 88
PubMed
Spanier J., Lienenklaus Stefan, Paijo J., Kessler A., Borst K., Heindorf Sabrina, Baker D.P., Kröger Andrea, Weiss Siegfried, Detje C.N., ... , Staeheli P., Kalinke Ulrich (2014)
Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus Infection
Journal of Immunology, 193 (6)
Marandu T.F., Finsterbusch K., Kroger A., Cicin-Sain L. (2014)
Mouse CMV infection delays antibody class switch upon an unrelated virus challenge
Experimental Gerontology, 54
DOI: 10.1016/j.exger.2014.01.017 HZI-Repositorium PubMed
Andzinski Lisa, Wu Ching-Fang, Lienenklaus Stefan, Kröger Andrea, Weiss Siegfried, Jablonska Jadwiga (2014)
Delayed apoptosis of tumor associated neutrophils in the absence of endogenous IFN-b[beta]
International Journal of Cancer, 136 (3)
DOI: 10.1002/ijc.28957 PubMed
Nair Sharmila, Michaelsen-Preusse K., Finsterbusch Katja, Stegemann-Koniszewski Sabine, Bruder Dunja, Grashoff Martina, Korte Martin, Köster Mario, Kalinke Ulrich, ... , Hauser Hansjörg, Kröger Andrea (2014)
Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons
PLoS Pathogens, 10 (3)
DOI: 10.1371/journal.ppat.1003999 HZI-Repositorium PubMed
Ksienzyk A., Neumann B., Kröger Andrea (2012)
IRF-1 is critical for IFNgamma mediated immune surveillance
Oncoimmunology, 1 (4)
DOI: 10.4161/onci.19405 HZI-Repositorium PubMed
Nandakumar R., Finsterbusch K., Lipps C., Neumann B., Grashoff M., Nair S., Hochnadel I., Lienenklaus S., Wappler I., Steinmann E., Hauser H., ... , Pietschmann T., Kröger A. (2013)
Hepatitis C Virus Replication in Mouse Cells is Restricted by IFN-Dependent and -Independent Mechanisms
Gastroenterology, 145 (6)
DOI: 10.1053/j.gastro.2013.08.037 HZI-Repositorium PubMed
Frentzen Anne, Kusuma Angga, Guerlevik E., Hueging Kathrin, Knocke S., Ginkel Corinne, Brown Richard J.P., Heim M., Dill M.T., Kröger Andrea, Kalinke Ulrich, Kaderali L., ... , Kuehnel F., Pietschmann Thomas (2013)
Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells
Hepatology
DOI: 10.1002/hep.26626 HZI-Repositorium PubMed
Rand Ulfert, Rinas M., Schwerk Johannes, Nohren G., Linnes M., Kröger Andrea, Flossdorf M., Kaly-Kullai K., Hauser Hansjörg, ... , Hofer T., Köster Mario (2012)
Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response
Molecular Systems Biology, 8
DOI: 10.1038/msb.2012.17
Ksienzyk A., Neumann B., Nandakumar R., Finsterbusch K., Grashoff M., Zawatzky R., Bernhardt G., ... , Hauser Hansjörg*, Kroger A. (2011)
IRF-1 Expression Is Essential for Natural Killer Cells to Suppress Metastasis
Cancer Research, 71 (20)
Ramsauer K., Farlik M., Zupkovitz G., Seiser C., Kroger A., ... , Hauser Hansjörg*, Decker T. (2007)
Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene
Proceeding of the National Acadamy of Sciences USA, 104 (8)
DOI: 10.1073/pnas.0610944104 HZI-Repositorium PubMed
Stirnweiss A., Ksienzyk A., Klages K., Rand U., Grashoff M., ... , Hauser Hansjörg*, Kroger A. (2010)
IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction
Journal of Immunology, 184 (9)
Dietrich N., Rohde Manfred*, Geffers Robert*, Kroger A., Hauser Hansjörg*, ... , Weiss Siegfried*, Gekara N.O. (2010)
Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteria
Proceeding of the National Academy of Sciences of the United States of America, 107 (19)
Probst-Kepper M., Geffers R., Kroger A., Viegas N., Erck C., Hecht H.-J., Lünsdorf H., Roubin R., Moharregh-Khiabani D., Wagner K., Ocklenburg F., Jeron A., Garritsen H., Arstila T.P., Kekalainen E., Balling R., Hauser H., ... , Buer J., Weiss S. (2009)
GARP: a key receptor controlling FOXP3 in human regulatory T cells
Journal of Cellular and Molecular Medicine, 13 (9)
Probst-Kepper Michael*, Kröger Andrea*, Garritsen H.S.P., Buer J. (2009)
Perspectives on regulatory T cell therapies
Transfusion Medicine and Hemotherapy, 36 (5)
Kroger A., Stirnweiss A., Pulverer J.E., Klages K., Grashoff M., ... , Reimann J., Hauser Hansjörg* (2007)
Tumor suppression by IFN regulatory factor-1 is mediated by transcriptional down-regulation of cyclin D1
Cancer Research, 67 (7)
Stegemann S., Dahlberg S., Kroger A., Gereke M., Bruder Dunja*, ... , Henriques-Normark B., Gunzer Matthias* (2009)
Increased susceptibility for superinfection with Streptococcus pneumoniae
PLoS ONE, 4 (3)
DOI: 10.1371/journal.pone.0004840 HZI-Repositorium PubMed
Schirmbeck R., Riedel P., Kupferschmitt M., Wegenka U., Hauser Hansjörg*, ... , Rice J., Kröger Andrea* (2006)
Priming protective CD8 T cell immunity by DNA vaccines encoding chimeric, stress protein-capturing tumor-associated antigen
Journal of Immunology, 177 (3)
Froese N., Schwarzer M., Niedick I., Frischmann U., Köster M., Kröger A., Müller P.P., Nourbakhsh M., Pasche B., Reimann J., ... , Staeheli P., Hauser H. (2006)
Innate immune responses in NF-kappaB-repressing factor (NRF)-deficient mice
Molecular and Cellular Biology, 26
DOI: 10.1128/MCB.26.1.293-302.2006 HZI-Repositorium PubMed
May T., Müller P., Weich H., Froese N., Deutsch U., Wirth D., ... , Kröger A., Hauser H. (2005)
Establishment of murine cell lines by constitutive and conditional immortalization
Journal of Biotechnology, 120 (1)
Dikopoulos N., Bertoletti A., Kröger A., Hauser H., Schirmbeck R., Reimann J. (2005)
Type I interferon negatively regulates CD8+ T cell responses through IL-10-producing CD4+ TR1 cells
Journal of Immunology, 174
Dikopoulos N., Wegenka U., Kröger A., Hauser H., Schirmbeck R., Reimann J. (2004)
Recently primed CD8+ T cells entering the liver allow hepatocytes to interact with naive CD8+ T cell and downregulate their immune-suppressive effects
Hepatology, 39
Jomantaité I., Dikopoulos N., Kröger A., Leithäuser F., Hauser H., ... , Schrimbeck R., Reimann J. (2004)
Hepatic dendritic cell subsets in the mouse
European Journal of Immunology, 34
Kröger A., Dallügge A., Kirchhoff S., Hauser H. (2003)
IRF-1 reverts the transformed phenotype of oncogenically transformed cells in vitro an in vivo
Oncogene, 22 (7)
Kwissa M., Kröger A., Hauser H., Reimann J., Schirmbeck R. (2003)
Defining conditions for cytokine-facilitated priming of CD8+ T cell responses by DNA vaccination
Journal of Molecular Medicine, 81
Trobonjaca Z., Kröger A., Stober D., Leithauser F., Moller P., Hauser H., ... , Schirmbeck R., Reimann J. (2002)
Activating immunity in the liver. II. IFN-beta attenuates NK cell- dependent liver injury triggered by liver NKT cell activation
Journal of Immunology, 168 (8)
Kröger A., Köster M., Schroeder K., Hauser H., Müller P.P. (2002)
Activities of IRF-1
Journal of Interferon and Cytokine Research, 22 (1)
Unsinger J., Kroger A., Hauser H., Wirth D. (2001)
Retroviral vectors for the transduction of autoregulated, bidirectional expression cassettes
Molecular therapy, 4 (5)
Müller P., Oumard A., Wirth D., Kröger A., Hauser H. (2001)
Polyvalent vectors for coexpression of multiple genes
Kröger A., Ortmann D., Krohne T.U., Mohr L., Blum H.E., ... , Hauser H., Geissler M. (2001)
Growth suppression of the hepatocellular carcinoma cell line Hepa1-6 by an activatable interferon regulatory factor-1 in mice
Cancer Research, 61 (6)
Hennecke M., Kwissa M., Metzger K., Oumard A., Kröger A., Schirmbeck R., ... , Reimann J., Hauser H. (2001)
Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs
Nucleic Acids Research, 29 (16)
HZI-Repositorium PubMed

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