Prof. Dr. Lothar Jänsch

Marecic V., Shevchuk O., Link M., Viduka I., Ozanic M., Kostanjsek R., Mihelcic M., Antonic M., Jänsch L., ... , Stulik J., Santic M. (2024)

Francisella novicida-Containing Vacuole within Dictyostelium discoideum: Isolation and Proteomic Characterization

Microorganisms., 12 (10)

DOI: 10.3390/microorganisms12101949 HZI-Repositorium PubMed

Garza A.P., Wider-Eberspächer E., Morton L., Van Ham M., Pallinger E., Buzas E.I., ... , Jänsch L., Dunay I.R. (2024)

Proteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons

Sci.Rep., 14 (1)

DOI: 10.1038/s41598-024-74228-4 HZI-Repositorium PubMed

Behlendorf C., Diwo M., Neumann-Schaal M., Fuchs M., Körner D., Jänsch L., ... , Faber F., Blankenfeldt W. (2024)

Formation of the pyruvoyl-dependent proline reductase Prd from Clostridioides difficile requires the maturation enzyme PrdH

PNAS Nexus, 3 (7)

DOI: 10.1093/pnasnexus/pgae249 HZI-Repositorium PubMed

Schöl M., Schempp R., Hennig T., Wigger D., Schumacher F., Kleuser B., Stigloher C., Van Ham M., Jänsch L., Schneider-Schaulies S., ... , Dölken L., Avota E. (2024)

Dynamic changes in the proximitome of neutral sphingomyelinase-2 (nSMase2) in TNFa[alpha] stimulated Jurkat cells

Frontiers in Immunology, 15

DOI: 10.3389/fimmu.2024.1435701 HZI-Repositorium PubMed

Schempp R., Eilts J., Schöl M., Grijalva Yepez M.F., Fekete A., Wigger D., Schumacher F., Kleuser B., Van Ham M., Jänsch L., ... , Sauer M., Avota E. (2024)

The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells

Int.J.Mol.Sci, 25 (6)

DOI: 10.3390/ijms25063247 HZI-Repositorium PubMed

Jerye K., Lüken H., Steffen A., Schlawis C., Jänsch L., ... , Schulz S., Brönstrup M. (2024)

Activity-Based Protein Profiling Identifies Protein Disulfide-Isomerases as Target Proteins of the Volatile Salinilactones

Adv.Sci.

DOI: 10.1002/advs.202309515 HZI-Repositorium PubMed

Brauns S., Marquardt I., Thon C., Frentzel S., Jakob J., Färber J., Philipsen L., Jänsch L., ... , Link A., Bruder D. (2023)

Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity

Int.Immunol.

DOI: 10.1093/intimm/dxad032 PubMed

Bi W., Kraft A., Engelskircher S., Mischke J., Witte M., Klawonn F., Van Ham M., Cornberg M., Wedemeyer H., ... , Hengst J., Jänsch L. (2023)

Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct-acting antivirals

Eur.J.Immunol.

DOI: 10.1002/eji.202250291 HZI-Repositorium PubMed

Schwanke H., Goncalves Magalhäes V, Schmelz S., Wyler E., Hennig T., Günther T., Grundhoff A., Dölken L., Landthaler M., Van Ham M., Jänsch L., Büssow K., van den Heuvel J., Blankenfeldt W., Friedel C.C., ... , Erhard F., Brinkmann M.M. (2023)

The Cytomegalovirus M35 Protein Directly Binds to the Interferon-b[beta] Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes

J.Virol., 97 (6)

DOI: 10.1128/jvi.00400-23 HZI-Repositorium PubMed

Esmaeeli M., Nimtz M., Jänsch L., Ruddock L.W., Leimkühler S. (2023)

Mechanistic insights into the ROS-mediated inactivation of human aldehyde oxidase

FEBS Lett.

DOI: 10.1002/1873-3468.14669 PubMed

Esmaeeli M., Nimtz M., Jänsch L., Ruddock L.W., Leimkühler S. (2023)

Inactivation of Human Aldehyde Oxidase by Small Sulfhydryl-containing Reducing Agents

Drug Metab Dispos.

DOI: 10.1124/dmd.122.001244 HZI-Repositorium PubMed

Borgert S.R., Henke S., Witzgall F., Schmelz S., Zur Lage S., Hotop S.K., Stephen S., Lübken D., Krüger J., Gomez N.O., Van Ham M., Jänsch L., Kalesse M., Pich A., Brönstrup M., ... , Häußler S., Blankenfeldt W. (2022)

Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-35030-w HZI-Repositorium PubMed

Prabhakar P., Pielot R., Landgraf P., Wissing J., Bayrhammer A., Van Ham M., Gundelfinger E.D., Jänsch L., ... , Dieterich D.C., Müller A. (2022)

Monitoring regional astrocyte diversity by cell type-specific proteomic labeling in vivo

Glia

DOI: 10.1002/glia.24304 HZI-Repositorium PubMed

Marquardt I., Jakob J., Scheibel J., Hofmann J.D., Klawonn F., Neumann-Schaal M., Gerhard R., ... , Bruder D., Jänsch L. (2021)

Clostridioides difficile Toxin CDT Induces Cytotoxic Responses in Human Mucosal-Associated Invariant T (MAIT) Cells

Front Microbiol., 12

DOI: 10.3389/fmicb.2021.752549 HZI-Repositorium PubMed

Zapatero-Belinchón F.J., Moeller R., Lasswitz L., Van Ham M., Becker M., Brogden G., Rosendal E., Bi W., Carriquí-Madronal B., Islam K., Lenman A., Gunesch A.P., Kirui J., Pietschmann T., Överby A.K., ... , Jänsch L., Gerold G. (2021)

Fluvastatin mitigates SARS-CoV-2 infection in human lung cells

iScience, 24 (12)

DOI: 10.1016/j.isci.2021.103469 HZI-Repositorium PubMed

Fuchs S., Kucklick M., Lehmann E., Beckmann A., Wilkens M., Kolte B., Mustafayeva A., Ludwig T., Diwo M., Wissing J., Jänsch L., Ahrens C.H., ... , Ignatova Z., Engelmann S. (2021)

Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach

PLoS.Genet., 17 (6)

DOI: 10.1371/journal.pgen.1009585 HZI-Repositorium PubMed

Dominguez-Perez D., Almeida D., Wissing J., Machado A.M., Jänsch L., Antunes A., Castro L.F., Vasconcelos V., ... , Campos A., Cunha I. (2021)

Proteogenomic characterization of the cement and adhesive gland of the pelagic gooseneck barnacle lepas anatifera

Int.J.Mol.Sci., 22 (7)

DOI: 10.3390/ijms22073370 HZI-Repositorium PubMed

Troitzsch D., Zhang H., Dittmann S., Düsterhöft D., Möller T.A., Michel A.M., Jänsch L., Riedel K., Borrero-de Acuna J.M., ... , Jahn D., Sievers S. (2021)

A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630 D

mSphere., 6 (2)

DOI: 10.1128/mSphere.00091-21 HZI-Repositorium PubMed

Chaoprasid P., Lukat P., Mühlen S., Heidler T., Gazdag E.M., Dong S., Bi W., Rüter C., Kirchenwitz M., Steffen A., Jänsch L., Stradal T.E.B., ... , Dersch P., Blankenfeldt W. (2021)

Crystal structure of bacterial cytotoxic necrotizing factor CNF g

EMBO J, 40 (4)

DOI: 10.15252/embj.2020105202 HZI-Repositorium PubMed

Wiesselmann M., Hebecker S., Borrero-de Acuna J.M., Nimtz M., Bollivar D.W., Jänsch L., ... , Moser J., Jahn D. (2020)

Mg-protoporphyrin IX monomethyl ester cyclase from Rhodobacter capsulatus: Radical SAM-dependent synthesis of the isocyclic ring of bacteriochlorophylls

Biochem.J., 477 (23)

DOI: 10.1042/BCJ20200761 HZI-Repositorium PubMed

Moreira G.M.S.G., Köllner S.M.S., Helmsing S., Jänsch L., Meier A., Gronow S., Boedeker C., Dübel S., Mendonca M., Moreira Á.N., ... , Conceicao F.R., Hust M. (2020)

Pyruvate dehydrogenase complex-enzyme 2, a new target for Listeria spp. detection identified using combined phage display technologies

Sci.Rep., 10 (1)

DOI: 10.1038/s41598-020-72159-4 HZI-Repositorium PubMed

Zafar M., Jahan H., Shafeeq S., Nimtz M., Jänsch L., ... , Römling U., Choudhary M.I. (2020)

Clarithromycin Exerts an Antibiofilm Effect against Salmonella typhimurium rdar Biofilm Formation, and Transforms the Physiology towards an Apparent Oxygen-depleted Energy and Carbon Metabolism

Infect.Immun., 88 (11)

DOI: 10.1128/IAI.00510-20 HZI-Repositorium PubMed

Klünemann T., Nimtz M., Jänsch L., Layer G., Blankenfeldt W. (2021)

Crystal structure of NirF: Insights into its role in heme d1 biosynthesis

FEBS J., 188 (1)

DOI: 10.1111/febs.15323 HZI-Repositorium PubMed

Dominguez-Perez D., Almeida D., Wissing J., Machado A.M., Jänsch L., Castro L.F., Antunes A., Vasconcelos V., ... , Campos A., Cunha I. (2020)

The quantitative proteome of the cement and adhesive gland of the pedunculate barnacle, pollicipes pollicipes

Int.J.Mol.Sci., 21 (7)

DOI: 10.3390/ijms21072524 HZI-Repositorium PubMed

Böning M.A.L., Trittel S., Riese P., Van Ham M., Heyner M., Voss M., Parzmair G.P., Klawonn F., Jeron A., Guzmán C.A., Jänsch L., Schraven B., ... , Reinhold A., Bruder D. (2020)

ADAP Promotes Degranulation and Migration of NK Cells Primed During in vivo Listeria monocytogenes Infection in Mice

Front.Immunol., 10

DOI: 10.3389/fimmu.2019.03144 HZI-Repositorium PubMed

Bernal I., Van Ham M., Jänsch L. (2020)

Immune Monitoring of Human Mucosal-Associated Invariant T Cells by Quantitative Proteomics

Methods Mol.Biol., 2098 (14)

DOI: 10.1007/978-1-0716-0207-2_14 PubMed

Kamal S.M., Rybtke M.L., Nimtz M., Sperlein S., Giske C., Trcek J., Deschamps J., Briandet R., Dini L., Jänsch L., Tolker-Nielsen T., ... , Lee C., Römling U. (2019)

Two FtsH proteases contribute to fitness and adaptation of pseudomonas aeruginosa Clone C strains

Front.Microbiol., 10 (JULY)

DOI: 10.3389/fmicb.2019.01372 HZI-Repositorium PubMed

Antenucci F., Magnowska Z., Nimtz M., Roesch C., Jänsch L., Bojesen A.M. (2019)

Immunoproteomic characterization of outer membrane vesicles from hyper-vesiculating Actinobacillus pleuropneumoniae

Vet.Microbiol., 235 (Aug)

DOI: 10.1016/j.vetmic.2019.07.001 PubMed

Klahn P., Fetz V., Ritter A., Collisi W., Hinkelmann B., Arnold T., Tegge W., Rox K., Hüttel S., Mohr K.I., Wink J., Stadler M., Wissing J., ... , Jänsch L., Brönstrup M. (2019)

The nuclear export inhibitor aminoratjadone is a potent effector in extracellular-targeted drug conjugates

Chem.Sci., 10 (20)

DOI: 10.1039/c8sc05542d HZI-Repositorium PubMed

Ünal C.M., Karagoz M.S., Berges M., Priebe C., Borrero de Acuna J.M., Wissing J., Jänsch L., ... , Jahn D., Steinert M. (2019)

Pleiotropic Clostridioides difficile Cyclophilin PpiB Controls Cysteine-Tolerance, Toxin Production, the Central Metabolism and Multiple Stress Responses

Front Pharmacol., 10 (4)

DOI: 10.3389/fphar.2019.00340 HZI-Repositorium PubMed

Li F., Cimdins A., Rohde M., Jänsch L., Kaever V., ... , Nimtz M., Römling U. (2019)

DncV Synthesizes Cyclic GMP-AMP and Regulates Biofilm Formation and Motility in Escherichia coli ECOR31

MBio, 10 (2)

DOI: 10.1128/mBio.02492-18 HZI-Repositorium PubMed

Bernal I., Hofmann J.D., Bulitta B., Klawonn F., Michel A.M., Jahn D., Neumann-Schaal M., ... , Bruder D., Jänsch L. (2018)

Clostridioides difficile activates human mucosal-associated invariant t cells

Front.Microbiol., 9 (OCT)

DOI: 10.3389/fmicb.2018.02532 HZI-Repositorium PubMed

Lang D., Schott B.H., Van Ham M., Morton L., Kulikovskaja L., Herrera-Molina R., Pielot R., Klawonn F., Montag D., Jänsch L., Gundelfinger E.D., ... , Smalla K.H., Dunay I.R. (2018)

Chronic Toxoplasma infection is associated with distinct alterations in the synaptic protein composition

J.Neuroinflamm., 15 (1)

DOI: 10.1186/s12974-018-1242-1 HZI-Repositorium PubMed

Voigt J., Malone D.F.G., Dias J., Leeansyah E., Björkstrom N.K., Ljunggren H.G., Gröbe L., Klawonn F., Heyner M., ... , Sandberg J.K., Jänsch L. (2018)

Proteome analysis of human CD56(neg) NK cells reveals a homogeneous phenotype surprisingly similar to CD56(dim) NK cells

Eur.J.Immunol., 48 (9)

DOI: 10.1002/eji.201747450

Groenewold M.K., Massmig M., Hebecker S., Danne L., Magnowska Z., Nimtz M., Narberhaus F., Jahn D., Heinz D.W., ... , Jänsch L., Moser J. (2018)

A phosphatidic acid binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa

Biochem.J., 475 (11)

DOI: 10.1042/BCJ20180257

Bulitta B., Zuschratter W., Bernal I., Bruder D., Klawonn F., von Bergen M., ... , Garritsen H.S.P., Jänsch L. (2018)

Proteomic definition of human mucosal-associated invariant T cells determines their unique molecular effector phenotype

Eur.J.Immunol., 48 (8)

DOI: 10.1002/eji.201747398

Bussey K.A., Lau U., Schumann S., Gallo A., Osbelt L., Stempel M., Arnold C., Wissing J., Gad H.H., Hartmann R., Brune W., Jänsch L., ... , Whitehouse A., Brinkmann M.M. (2018)

The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein

PLoS.Pathog., 14 (3)

DOI: 10.1371/journal.ppat.1006937 HZI-Repositorium PubMed

Kaufmann P., Duffus B.R., Mitrova B., Iobbi-Nivol C., Teutloff C., Nimtz M., Jänsch L., ... , Wollenberger U., Leimkühler S. (2018)

Modulating the Molybdenum Coordination Sphere of Escherichia coli Trimethylamine N-Oxide Reductase

Biochemistry, 57 (7)

DOI: 10.1021/acs.biochem.7b01108

Lee C., Franke K.B., Kamal S.M., Kim H., Lünsdorf H., Jager J., Nimtz M., Trcek J., Jänsch L., Bukau B., ... , Mogk A., Römling U. (2017)

Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria

Proc.Natl.Acad.Sci.U.S.A, 115 (2)

DOI: 10.1073/pnas.1712051115 HZI-Repositorium PubMed

Litschko C., Linkner J., Bruhmann S., Stradal T.E.B., Reinl T., Jänsch L., ... , Rottner K., Faix J. (2017)

Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes

Eur.J.Cell Biol., 96 (8)

DOI: 10.1016/j.ejcb.2017.08.003 PubMed

Van Ham M., Teich R., Philipsen L., Niemz J., Amsberg N., Wissing J., Nimtz M., Grobe L., Kliche S., Thiel N., Klawonn F., Hubo M., Jonuleit H., Reichardt P., Muller A.J., ... , Hühn J., Jänsch L. (2017)

TCR signalling network organization at the immunological synapses of murine regulatory T cells

Eur.J.Immunol., 47 (12)

DOI: 10.1002/eji.201747041 HZI-Repositorium PubMed

Niemz J., Kliche S., Pils M.C., Morrison E., Manns A., Freund C., Crittenden J.R., Graybiel A.M., Galla M., ... , Jänsch L., Hühn J. (2017)

The Guanine-Nucleotide Exchange Factor Caldag Gefi Fine-Tunes Functional Properties of Regulatory T Cells

Eur.J.Microbiol.Immunol.(Bp), 7 (2)

DOI: 10.1556/1886.2017.00007 HZI-Repositorium

Boehme J.D., Stegemann-Koniszewski S., Autengruber A., Peters N., Wissing J., Jänsch L., ... , Jeron A., Bruder D. (2017)

Chronic lung inflammation primes humoral immunity and augments antipneumococcal resistance

Sci.Rep., 7 (1)

DOI: 10.1038/s41598-017-05212-4 PubMed

Lingel H., Wissing J., Arra A., Schanze D., Lienenklaus S., Klawonn F., Pierau M., Zenker M., ... , Jänsch L., Brunner-Weinzierl M.C. (2017)

CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation

Cell Death.Differ., 24 (10)

DOI: 10.1038/cdd.2017.102 HZI-Repositorium

Kummer A., Nishanth G., Koschel J., Klawonn F., Schluter D., Jänsch L. (2016)

Listeriosis down-regulates hepatic cytochrome P450 enzymes in sub-lethal murine infection

Proteomics Clin.Appl., 10 (9-10)

DOI: 10.1002/prca.201600030 PubMed

Borrero-de Acuna J.M., Rohde M., Wissing J., Jänsch L., Schobert M., Molinari G., Timmis K.N., ... , Jahn M., Jahn D. (2016)

The Protein Network of the Pseudomonas aeruginosa Denitrification Apparatus

J Bacteriol., 198 (9)

DOI: 10.1128/JB.00055-16 HZI-Repositorium PubMed

Düvel J., Bense S., Möller S., Bertinetti D., Schwede F., Morr M., Eckweiler D., Genieser H.G., Jänsch L., Herberg F.W., ... , Frank R., Häußler S. (2016)

Application of synthetic peptide arrays to uncover cyclic Di-GMP binding motifs

J Bacteriol., 198

DOI: 10.1128/JB.00377-15 HZI-Repositorium PubMed

Borrero-de Acuna J.M., Molinari G., Rohde M., Dammeyer T., Wissing J., Jänsch L., Arias S., Jahn M., Schobert M., ... , Timmis K.N., Jahn D. (2015)

A periplasmic complex of the nitrite reductase NirS, the chaperone DnaK, and the flagellum protein FliC is essential for flagellum assembly and motility in Pseudomonas aeruginosa

J.Bacteriol., 197 (19)

DOI: 10.1128/JB.00415-15 HZI-Repositorium PubMed

Wirsing L., Klawonn F., Sassen W.A., Lünsdorf H., Probst C., Hust M., Mendel R.R., ... , Kruse T., Jänsch L. (2015)

Linear Discriminant Analysis Identifies Mitochondrially Localized Proteins in Neurospora crassa

J Proteome.Res, 14 (9)

Ringel P., Probst C., Dammeyer T., Buchmeier S., Jänsch L., Wissing J., Tinnefeld P., Mendel R.R., ... , Jockusch B.M., Kruse T. (2015)

Enzymatic characterization of recombinant nitrate reductase expressed and purified from Neurospora crassa

Fungal Genet.Biol., 80

Shevchuk Olga, Abidi Nada, Klawonn Frank, Wissing Josef, Nimtz Manfred, Kugler C., Steinert M., ... , Goldmann T., Jänsch Lothar (2014)

HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies

Journal of Proteome Research, 13 (11)

Schreiber L., Pietzsch B., Flöß S., Farah C., Jänsch L., ... , Schmitz I., Hühn J. (2014)

The Treg-specific demethylated region stabilizes Foxp3 expression independently of NF-?B signaling

PLoS ONE, 9 (2)

DOI: 10.1371/journal.pone.0088318 HZI-Repositorium PubMed

Magnowska Z., Hartmann I., Jänsch Lothar, Jahn D. (2014)

Membrane Proteomics of Pseudomonas aeruginosa

Methods in Molecular Biology, 1149

Gamrekelashvili J., Kapanadze T., Han M., Wissing J., Ma C., Jänsch Lothar, Manns M.P., Armstrong T., Jaffee E., White A.O., Citrin D.E., ... , Korangy F., Greten T.F. (2013)

Peptidases released by necrotic cells control CD8+ T cell cross-priming

Journal of Clinical Investigation, 123 (11)

DOI: 10.1172/JCI65698 HZI-Repositorium PubMed

Tielen P., Rosin N., Meyer A.K., Dohnt K., Haddad I., Jänsch Lothar, Klein J., Narten M., Pommerenke C., Scheer M., Schobert M., Schomburg D., ... , Thielen B., Jahn D. (2013)

Regulatory and Metabolic Networks for the Adaptation of Pseudomonas aeruginosa

PLoS ONE, 8 (8)

DOI: 10.1371/journal.pone.0071845 HZI-Repositorium PubMed

Nicke T., Schnitzer T., Münch K., Adamczack J., Haufschildt K., Buchmeier S., Kucklick M., Felgenträger Undine, Jänsch Lothar, ... , Riedel K., Layer G. (2013)

Maturation of the cytochrome cd1 nitrite reductase NirS from Pseudomonas aeruginosa requires transient interactions between the three proteins NirS, NirN and NirF

Bioscience Reports, 33 (3)

DOI: 10.1042/BSR20130043 HZI-Repositorium PubMed

Scheiter Maxi, Lau Ulrike, van Ham Marco, Bulitta Björn, Gröbe Lothar, Garritsen H., Klawonn Frank, ... , Konig S., Jänsch Lothar (2013)

Proteome analysis of distinct developmental stages of human natural killer (NK) cells

Molecular and Cellular Proteomics, 12 (5)

DOI: 10.1074/mcp.M112.024596 HZI-Repositorium PubMed

Scheiter Maxi, Bulitta Björn, van Ham Marco, Klawonn Frank, Konig S., Jänsch Lothar (2013)

Protein Kinase Inhibitors CK59 and CID755673 Alter Primary Human NK Cell Effector Functions

Frontiers in Immunology, 4

DOI: 10.3389/fimmu.2013.00066 HZI-Repositorium PubMed

Johl T., Nimtz Manfred, Jänsch Lothar, Klawonn Frank (2012)

Detecting glycosylations in complex samples

IFIP Advances in Information and Communication Technology, 381 AICT (Part 1) (234)

Klawonn F., Abidi N., Berger E., Jänsch Lothar* (2012)

Curve fitting for short time series data from high throughput experiments with correction for biological variation

Lecture Notes in Computer Science, LNCS 7619

König S., Nimtz Manfred, Scheiter M., Ljunggren H.G., Bryceson Y.T., Jänsch Lothar (2012)

Kinome analysis of receptor-induced phosphorylation in human natural killer cells

PLoS ONE, 7 (1)

von Zur Muhlen C., Schiffer E., Sackmann C., Zurbig P., Neudorfer I., Zirlik A., Htun N., Iphofer A., Jänsch Lothar, Mischak H., Bode C., ... , Chen Y.C., Peter K. (2012)

Urine Proteome Analysis Reflects Atherosclerotic Disease in an ApoE-/- Mouse Model and Allows the Discovery of New Candidate Biomarkers in Mouse and Human Atherosclerosis

Molecular and Cellular Proteomics, 11 (7)

König S., Probst-Kepper M., Reinl T., Jeron A., Hühn Jochen, ... , Schraven B., Jänsch Lothar (2012)

First insight into the kinome of human regulatory T cells

PLoS ONE, 7 (7)

DOI: 10.1371/journal.pone.0040896 HZI-Repositorium PubMed

Iphofer A., Kummer A., Nimtz Manfred, Ritter A., Arnold T., Frank R., van den Heuvel Joop, Kessler B.M., ... , Jänsch Lothar, Franke R. (2012)

Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes

ChemBioChem, 13 (10)

Gernert C., Berger E., Klawonn F., Jänsch Lothar (2012)

Tackling misleading peptide regulation fold changes in quantitative proteomics

Advances in Intelligent and Soft Computing, 154

Gernert C., Klawonn Frank, Jänsch Lothar (2012)

SignalNet: Visualization of signal network responses by quantitative proteome data

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 6936 LNCS

Benkert B., Quack N., Schreiber K., Jänsch Lothar*, Jahn D., Schobert M. (2008)

Nitrate-responsive NarX-NarL represses arginine-mediated induction of the Pseudomonas aeruginosa arginine fermentation arcDABC operon1

Microbiology, 154 (Pt 10)

Düvel J., Bertinetti D., Moller S., Schwede F., Morr M., Wissing J., Radamm L., Zimmermann B., Genieser H.G., Jänsch Lothar, ... , Herberg F.W., Häußler Susanne (2012)

A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa

Journal of Microbiological Methods, 88 (2)

DOI: 10.1016/j.mimet.2011.11.015 PubMed

Pommerenke C., Friedrich B., Johl T., Jänsch Lothar, Häußler Susanne, Klawonn F. (2012)

A modified apriori algorithm for analysing high-dimensional gene data

LNCS, 6936

Bodor A.M., Jänsch Lothar*, Wissing J., Wagner-Döbler Irene* (2011)

The luxS mutation causes loosely-bound biofilms in Shewanella oneidensis

BMC Research Notes, 4 (1)

DOI: 10.1186/1756-0500-4-180 HZI-Repositorium PubMed

Novoselova N., Klawonn Frank*, Johl T., Reinl T., Jänsch Lothar* (2011)

Identification of peptides with deviating regulation factors using a robust clustering scheme

Advances in Intelligent and Soft Computing, 93

Hemmen K., Reinl T., Buttler K., Behler F., Dieken H., Jänsch Lothar*, ... , Wilting J., Weich Herbert A.* (2011)

High-resolution mass spectrometric analysis of the secretome from mouse lung endothelial progenitor cells

Angiogenesis, 14 (2)

DOI: 10.1007/s10456-011-9200-x HZI-Repositorium PubMed

Metzger J., Chatzikyrkou C., Broecker V., Schiffer E., Jänsch Lothar*, Iphoefer A., Mengel M., Mullen W., Mischak H., ... , Haller H., Gwinner W. (2011)

Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis

Proteomics -Clinical Applications, 5 (5-6)

DOI: 10.1002/prca.201000153 PubMed

Babiychuk E., Vandepoele K., Wissing J., Garcia-Diaz M., De Rycke R., Akbari H., Joubes J., Beeckman T., Jänsch Lothar*, Frentzen M., ... , Van Montagu M.C., Kushnir S. (2011)

Plastid gene expression and plant development require a plastidic protein of the mitochondrial transcription termination factor family

Proceedings of the National Academy of Sciences USA, 108 (16)

DOI: 10.1073/pnas.1103442108 PubMed

Bartsch A., Bunk B., Haddad I., Klein J., Munch R., Johl T., Karst U., Jänsch Lothar*, ... , Jahn D., Retter I. (2011)

GeneReporter--sequence-based document retrieval and annotation

Bioinformatics, 27 (7)

DOI: 10.1093/bioinformatics/btr047 HZI-Repositorium PubMed

Schmidt J., Musken M., Becker T., Magnowska Z., Bertinetti D., Moller S., Zimmermann B., Herberg F.W., ... , Jansch L., Häußler Susanne* (2011)

The Pseudomonas aeruginosa Chemotaxis Methyltransferase CheR1 Impacts on Bacterial Surface Sampling

PLoS ONE, 6 (3)

DOI: 10.1371/journal.pone.0018184 HZI-Repositorium PubMed

Trunk K., Benkert B., Quack N., Munch R., Scheer M., Garbe J., Jänsch Lothar*, Trost M., Wehland Jürgen*, Buer J., Jahn M., ... , Schobert M., Jahn D. (2010)

Anaerobic adaptation in Pseudomonas aeruginosa

Environmental Microbiology, 12 (6)

Maahs D.M., Siwy J., Argiles A., Cerna M., Delles C., Dominiczak A.F., Gayrard N., Iphöfer A., Jänsch Lothar*, Jerums G., Medek K., Mischak H., Navis G.J., Roob J.M., Rossing K., Rossing P., Rychlik I., Schiffer E., Schmieder R.E., Wascher T.C., Winklhofer-Roob B.M., Zimmerli L.U., ... , Zurbig P., Snell-Bergeon J.K. (2010)

Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology

PLoS ONE, 5 (9)

DOI: 10.1371/journal.pone.0013051 HZI-Repositorium PubMed

Mischak H., Kolch W., Aivaliotis M., Bouyssie D., Court M., Dihazi H., Dihazi G.H., Franke J., Garin J., de Peredo A.G., Iphöfer A., Jänsch Lothar*, Lacroix C., Makridakis M., Masselon C., Metzger J., Monsarrat B., Mrug M., Norling M., Novak J., Pich A., Pitt A., Bongcam-Rudloff E., Siwy J., Suzuki H., Thongboonkerd V., Wang L.-S., Zoidakis J., Zurbig P., ... , Schanstra J.P., Vlahou A. (2010)

Comprehensive human urine standards for comparability and standardization in clinical proteome analysis

Proteomics - Clinical Applications, 4 (4)

Klodmann J., Sunderhaus S., Nimtz Manfred*, Jänsch Lothar*, Braun H.P. (2010)

Internal architecture of mitochondrial complex I from Arabidopsis thaliana

Plant Cell, 22 (3)

Reinl T., Nimtz M., Hundertmark C., Johl T., Keri G., Wehland Jürgen*, ... , Daub H., Jänsch Lothar* (2009)

Quantitative phosphokinome analysis of the met pathway activated by the invasin internalin B from Listeria monocytogenes

Molecular and Cellular Proteomics, 8 (12)

Mitzner D., Dudek S.E., Studtrucker N., Anhlan D., Mazur I., Wissing J., Jansch L., Wixler L., Bruns K., Sharma A., Wray Victor*, Henklein P., ... , Ludwig S., Schubert U. (2009)

Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes

Cellular Microbiology, 11 (10)

Dötsch A., Becker T., Pommerenke C., Magnowska Z., Jänsch Lothar*, Häußler Susanne* (2009)

Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 53 (6)

DOI: 10.1128/AAC.00035-09 HZI-Repositorium PubMed

Hundertmark C., Fischer R., Reinl T., May S., Klawonn F., Jänsch Lothar* (2009)

MS-specific noise model reveals the potential of iTRAQ in quantitative proteomics

Bioinformatics, 25 (8)

DOI: 10.1093/bioinformatics/btn551 HZI-Repositorium PubMed

Weiss S.M., Ladwein M., Schmidt D., Ehinger J., Lommel S., Städing K., Beutling U., Disanza A., Frank R., Jänsch L., Scita G., Gunzer F., ... , Rottner K., Stradal T.E. (2009)

IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation

Cell Host and Microbe, 5 (3)

Schroder S., Zhang H., Yeung E.S., Jänsch Lothar*, Zabel C., Watzig H. (2008)

Quantitative gel electrophoresis: sources of variation

Journal of Proteome Research, 7 (3)

Klein J., Leupold S., Munch R., Pommerenke C., Johl T., Karst U., Jänsch Lothar*, ... , Jahn D., Retter I. (2008)

ProdoNet: identification and visualization of prokaryotic gene regulatory and metabolic networks

Nucleic Acids Research, 36 (Web Server issue)

Machata S., Tchatalbachev S., Mohamed W., Jänsch Lothar*, Hain T., Chakraborty T. (2008)

Lipoproteins of Listeria monocytogenes are critical for virulence and TLR2-mediated immune activation

Journal of Immunology, 181 (3)

Millar A.H., Eubel H., Jänsch Lothar*, Kruft V., Heazlewood J.L., Braun H.P. (2004)

Mitochondrial cytochrome c oxidase and succinate dehydrogenase complexes contain plant specific subunits

Plant Molecular Biology, 56 (1)

Peters K., Dudkina N.V., Jänsch Lothar*, Braun H.P., Boekema E.J. (2008)

A structural investigation of complex I and I+III(2) supercomplex from Zea mays at 11-13 A resolution: Assignment of the carbonic anhydrase domain and evidence for structural heterogeneity within complex I

Biochimica et biophysica acta, 1777 (1)

DOI: 10.1016/j.bbabio.2007.10.012 HZI-Repositorium PubMed

Biedendieck R., Gamer M., Jänsch Lothar*, Meyer S., Rohde Manfred*, ... , Deckwer Wolf-Dieter*, Jahn D. (2007)

A sucrose-inducible promoter system for the intra- and extracellular protein production in Bacillus megaterium

Journal of Biotechnology, 132 (4)

DOI: 10.1016/j.jbiotec.2007.07.494 HZI-Repositorium

Phan-Thanh L., Jänsch Lothar* (2006)

Elucidation of mechanisms of acid stress in Listeria monocytogenes

Hain T., Chatterjee S.S., Ghai R., Kuenne C.T., Billion A., Steinweg C., Domann E., Kärst U., Jänsch L., Wehland J., Eisenreich W., Bacher A., Joseph B., Schär J., Kreft J., Klumpp J., Loessner M.J., Dorscht J., Neuhaus K., Fuchs T.M., Scherer S., Doumith M., Jacquet C., Martin P., Cossart P., Glaser P., Buchrieser C., ... , Goebel W., Chakraborty T. (2007)

Pathogenomics of Listeria

International Journal of Medical Microbiology, 297 (7-8)

DOI: 10.1016/j.ijmm.2007.03.016 PubMed

Schaumburg J., Diekmann O., Hagendorff P., Bergmann S., Rohde Manfred*, Hammerschmidt S., Jänsch Lothar*, ... , Wehland Jürgen*, Kärst Uwe* (2006)

The cell wall subproteome of Listeria monocytogenes

(9)

Newo A.N.S., Lützelberger M., Bottner C.A., Wehland Jürgen*, Wissing Josef*, ... , Jänsch Lothar*, Käufer N.F. (2007)

Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe

Nucleic Acids Research, 35 (5)

Wissing J., Jänsch L., Nimtz M., Dieterich G., Hornberger R., Keri G., ... , Wehland J., Daub H. (2007)

Proteomics analysis of protein kinases by target class-selective pre-fractionation and tandem mass spectrometry

Molecular & Cellular Proteomics, 6 (3)

DOI: 10.1074/mcp.T600062-MCP200 HZI-Repositorium PubMed

Baumgärtner M., Kärst Uwe*, Gerstel B., Loessner M., Wehland Jürgen*, Jänsch Lothar* (2007)

Inactivation of Lgt allows systematic characterization of lipoproteins from Listeria monocytogenes

Journal of Bacteriology, 189 (2)

DOI: 10.1128/JB.00976-06 HZI-Repositorium PubMed

Reinl Tobias*, Wissing Josef*, Fischer R., Hundertmark C., Klawonn F., Daub H., ... , Wehland Jürgen*, Jänsch Lothar* (2006)

Quantitative analysis of receptor tyrosine kinase signaling exploited by Listeria monocytogenes

Molecular & Cellular Proteomics, 5 (10)

Wegener C., Reinl T., Jänsch Lothar*, Predel R. (2006)

Direct mass spectrometric peptide profiling and fragmentation of larval peptide hormone release sites in Drosophila melanogaster reveals tagma-specific peptide expression and differential processing

Journal of Neurochemistry, 96 (5)

Sunderhaus S., Dudkina N.V., Jänsch Lothar*, Klodmann J., Heinemeyer J., Perales M., Zabaleta E., ... , Boekema E.J., Braun H.P. (2006)

Carbonic anhydrase subunits form a matrix-exposed domain attached to the membrane arm of mitochondrial complex I in plants

Journal of Biological Chemistry, 281 (10)

DOI: 10.1074/jbc.M511542200 HZI-Repositorium PubMed

Dieterich G., Kärst Uwe*, Fischer E., Wehland Jürgen*, Jänsch Lothar* (2006)

LEGER: knowledge database and visualization tool for comparative genomics of pathogenic and non-pathogenic Listeria species

Nucleic Acids Research, 34

Schreiber K., Boes N., Eschbach M., Jänsch Lothar*, Wehland J., Bjarnsholt T., Giskov M., ... , Hentzer M., Schobert M. (2006)

Anaerobic survival of Pseudomonas aeruginosa

Journal of Bacteriology, 188

DOI: 10.1128/JB.188.2.659-668.2006 HZI-Repositorium PubMed

Beller M., Riedel D., Jänsch Lothar*, Dieterich D., Wehland Jürgen*, ... , Jackle H., Kuhnlein R.P. (2006)

Characterization of the Drosophila Lipid Droplet Subproteome

Molecular & Cellular Proteomics, 5

DOI: 10.1074/mcp.M600011-MCP200 HZI-Repositorium PubMed

Thedieck K., Hain T., Mohamed W., Tindall B., Nimtz M., Chakraborty T., ... , Wehland J., Jänsch L. (2006)

The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Lysteria monocytogenes

Molecular Microbiology, 62

DOI: 10.1111/j.1365-2958.2006.05452.x HZI-Repositorium PubMed

Layer G., Pierik A.J., Trost M., Jänsch Lothar*, Leech H.K., Warren M.J., Rigby S.E., Astner I., Grage K., Breckau D., ... , Heinz Dirk W.*, Jahn D. (2006)

The substrate radical of Escherichia coli

Journal of Biological Chemistry, 281

Nalca Y., Jänsch Lothar*, Bredenbruch F., Geffers Robert*, Buer Jan*, Häußler Susanne* (2006)

Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 50

DOI: 10.1128/AAC.50.5.1680-1688.2006 HZI-Repositorium PubMed

Dieterich G., Kärst U., Wehland J., Jänsch L. (2006)

VIS-O-BAC: exploratory visualization of functional genome studies from bacteria

Bioinformatics, 22 (5)

DOI: 10.1093/bioinformatics/bti814 PubMed

Dieterich G., Kärst U., Wehland J., Jänsch L. (2005)

MineBlast: A literature presentation service supporting protein annotation by data Mining of blast results

Bioinformatics, 21

Wehmhöner D., Dieterich G., Fischer E., Baumgärtner M., Wehland J., Jänsch L. (2005)

"LaneSpector", a toll for membrane proteome profiling based on SDS-PAGE / LC-MS/MS analysis: Application to Listeria monocytogenes membrane proteins

Electrophoresis, 26

Trost M., Wehmhöner D., Kärst U., Dieterich G., Wehland J., Jänsch L. (2005)

Comparative proteome analysis of secretory proteins from pathogenic and non-pathogenic Listeria species

Proteomics, 5

Heinemeyer J., Eubel H., Wehmhöner D., Jänsch L., Braun H.P. (2004)

Proteomic approach to characterize the supramolecular organization of photosystems in higher plants

Phytochemistry, 65

Weig M., Jänsch L., Groß U., De Koster C.G., Klis F.M., De Groot P.W.J. (2004)

Systematic identification of covalently-bound cell wall proteins and analysis of protein-polysaccharide linkages of the human pathogen Candida glabrata

Microbiology, 150

Schaumburg J., Diekmann O., Hagendorff P., Bergmann S., Rohde M., Hammerschmidt S., Jänsch L., ... , Wehland J., Kärst U. (2004)

The cell wall subproteome of Listeria monocytogenes

Proteomics, 4

Werhahn W., Jänsch L., Braun H.P. (2003)

Identification of novel subunits of the tom complex from Arabidopsis thaliana.

Plant Physiology, 41

Ramnath M., Rechinger K.B., Jänsch L., Hastings J.W., Knochel S., Gravesen A. (2003)

The development of a Listeria monocytogenes EGDe proteome reference map and comparison with food isolates

Applied and Environmental Microbiology, 69 (6)

Helloin E., Jänsch L., Phan-Thanh L. (2003)

Carbon starvation survival of Listeria monocytogenes

Proteomics, 3 (10)

Focke M., Gieringer E., Schwan S., Jänsch L., Binder S., Braun H.P. (2003)

Fatty acid biosynthesis in mitochondria of grasses: malonlyl-CoA is integrated by a mitochondrial-localized acetyl-CoA carboxylase.

Plant Physiology, 133 (2)

DOI: 10.1104/pp.103.027375 HZI-Repositorium PubMed

Wehmhöner D., Häußler S., Tümmler B., Jänsch L., Wehland J., Steinmetz.I. (2003)

Inter - and intraclonal diversity of Pseudomonas aeruginosa proteome manifests within the secretome.

Journal of Bacteriology, 185 (19)

Eubel H., Jänsch L., Braun H.P. (2003)

New insights into the respiratory chain of plant mitochondria: supercomplexes and a unique composition of complex II.

Plant Physiology, 133 (1)

DOI: 10.1104/pp.103.024620 HZI-Repositorium PubMed

Gravesen A., Ramnath M., Rechinger K.B., Andersen N., Jänsch L., Héchard Y., ... , Hastings J.W., Knochel S. (2002)

High-level resistance to class IIa bacteriocins is associated with one general mechanism in Listeria monocytogenes.

Microbiology <Reading>, 148

Bierne H., Mazmanian S.K., Trost M., Pucciarelli M.G., Dehoux P., The European Listeria Genome Consortium, Jänsch L., Garcia-Del Portillo F., Schneewind O., Cossart P., Blöcker H., Brandt P., ... , Nordsiek G., Wehland J. (2002)

Inactivation of the srtA gene in Listeria monocytogenes

Molecular Microbiology, 43

DOI: 10.1046/j.1365-2958.2002.02798.x HZI-Repositorium

Werhahn W., Niemeyer A., Jänsch L., Kruft V., Schmitz U.K., Braun H.P. (2001)

Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. identification of multiple forms of TOM20.

Plant Physiology, 125

Kruft V., Eubel H., Jänsch L., Werhahn W., Braun H.P. (2001)

Proteomic approach to identify novel mitochondrial proteins in Arabidopsis.

Plant Physiology, 127

HZI-Repositorium PubMed

Singh P., Jänsch L., Braun H.P., Schmitz U.K. (2000)

Resolution of mitochondrial and chloroplast membrane protein complexes from green leaves of Potato on blue-native polyacrylamide gels.

Indian Journal of Biochemistry & Biophysics, 37

Prof. Dr. Lothar Jänsch

Prof. Dr. Lothar Jänsch

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