Prof. Dr. Theresia Stradal

Werbenko E., Gorter D.J.J., Kleimann S., Beckmann D., Waltereit-Kracke V., Reinhardt J., Geers F., Paruzel P., Hansen U., Pap T., ... , Stradal T.E.B., Dankbar B. (2024)

Hem1 is essential for ruffled border formation in osteoclasts and efficient bone resorption

Scientific Reports, 14 (1)

DOI: 10.1038/s41598-024-58110-x HZI-Repositorium PubMed

Fey C., Truschel T., Nehlsen K., Damigos S., Horstmann J., Stradal T., May T., ... , Metzger M., Zdzieblo D. (2024)

Enhancing pre-clinical research with simplified intestinal cell line models

J.Tissue Eng., 15

DOI: 10.1177/20417314241228949 HZI-Repositorium PubMed

Ravichandran Y., Hänisch J., Murray K., Roca V., Dingli F., Loew D., Sabatet V., Boeda B., ... , Stradal T.E., Etienne-Manneville S. (2024)

The distinct localization of CDC42 isoforms is responsible for their specific functions during migration

J.Cell Biol., 223 (3)

DOI: 10.1083/jcb.202004092 HZI-Repositorium PubMed

Sum W.C., Ebada S.S., Kirchenwitz M., Wanga L., Decock C., Stradal T.E.B., Matasyoh J.C., Mandi A., ... , Kurtan T., Stadler M. (2023)

Neurite Outgrowth-Inducing Drimane-Type Sesquiterpenoids Isolated from Cultures of the Polypore Abundisporus violaceus MUCL 56355

J.Nat.Prod., 86 (11)

DOI: 10.1021/acs.jnatprod.3c00525 HZI-Repositorium PubMed

Kirchenwitz M., Halfen J., von Peinen K., Prettin S., Kollasser J., Zur Lage S., Blankenfeldt W., Brakebusch C., Rottner K., ... , Steffen A., Stradal T.E.B. (2023)

RhoB promotes Salmonella survival by regulating autophagy

Eur.J.Cell Biol., 102 (4)

DOI: 10.1016/j.ejcb.2023.151358 HZI-Repositorium PubMed

Mitschke N., Chemutai Sum W., Hassan K., Kirchenwitz M., Schrey H., Gerhards L., Kellner H., Stradal T.E.B., ... , Matasyoh J.C., Stadler M. (2023)

Biologically active drimane derivatives isolated from submerged cultures of the wood-inhabiting basidiomycete Dentipellis fragilis

RSC Adv., 13 (37)

DOI: 10.1039/d3ra04204a HZI-Repositorium PubMed

Lambert C., Schmidt K., Karger M., Stadler M., Stradal T.E.B., Rottner K. (2023)

Cytochalasans and Their Impact on Actin Filament Remodeling

Biomolecules., 13 (8)

DOI: 10.3390/biom13081247 HZI-Repositorium PubMed

Sum W.C., Ebada S.S., Kirchenwitz M., Kellner H., Ibrahim M.A.A., Stradal T.E.B., ... , Matasyoh J.C., Stadler M. (2023)

Hericioic Acids A-G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

J.Agric.Food Chem.

DOI: 10.1021/acs.jafc.3c02897 HZI-Repositorium PubMed

Lambert C., Shao L., Zeng H., Surup F., Saetang P., Aime M.C., Husbands D.R., Rottner K., ... , Stradal T.E.B., Stadler M. (2023)

Cytochalasans produced by Xylaria karyophthora and their biological activities

Mycologia

DOI: 10.1080/00275514.2023.2188868 HZI-Repositorium PubMed

Stradal T.E.B., Kirchenwitz M., Steffen A. (2023)

Wirkstoffe an der Schnittstelle zwischen Autophagie und Cytoskelettdynamik [/ Active ingredients at the interface between autophagy and cytoskeletal dynamics]

Biospektrum, 29 (2)

DOI: 10.1007/s12268-023-1921-z HZI-Repositorium

Steffen A., Reusch B., Gruteser N., Mainz D., Roncarati R., Baumann A., ... , Stradal T.E.B., Knebel-Mörsdorf D. (2023)

Baculovirus Actin Rearrangement-Inducing Factor 1 Can Remodel the Mammalian Actin Cytoskeleton

Microbiol.Spectr.

DOI: 10.1128/spectrum.05189-22 HZI-Repositorium PubMed

Kemkuignou B.M., Lambert C., Schmidt K., Schweizer L., Anoumedem E.G.M., Kouam S.F., Stadler M., ... , Stradal T., Marin-Felix Y. (2023)

Unreported cytochalasins from an acid-mediated transformation of cytochalasin J isolated from Diaporthe cf. ueckeri

Fitoterapia

DOI: 10.1016/j.fitote.2023.105434 HZI-Repositorium PubMed

Hassan K., Matio Kemkuignou B., Kirchenwitz M., Wittstein K., Rascher-Albaghdadi M., Chepkirui C., Matasyoh J.C., Decock C., Köster R.W., ... , Stradal T.E.B., Stadler M. (2022)

Neurotrophic and Immunomodulatory Lanostane Triterpenoids from Wood-Inhabiting Basidiomycota

Int.J.Mol.Sci., 23 (21)

DOI: 10.3390/ijms232113593 HZI-Repositorium PubMed

Kirchenwitz M., Stahnke S., Grunau K., Melcher L., Van Ham M., Rottner K., ... , Steffen A., Stradal T.E.B. (2022)

The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection

Sci.Rep., 12 (1)

DOI: 10.1038/s41598-022-20563-3 HZI-Repositorium PubMed

Spindler M., Bergmeier W., Stradal T.E.B., Zhang J., Siminovitch K., Nicolai L., ... , Reinhold A., Bender M. (2022)

Novel insights into mouse models of ectopic proplatelet release

Blood Adv.

DOI: 10.1182/bloodadvances.2022007824 HZI-Repositorium PubMed

Pourmoghaddam M.J., Ekiz G., Lambert C., Surup F., Primahana G., Wittstein K., Khodaparast S.A., Voglmayr H., Krisai-Greilhuber I., ... , Stradal T.E.B., Stadler M. (2022)

Studies on the secondary metabolism of Rosellinia and Dematophora strains (Xylariaceae) from Iran

Mycol.Prog., 21 (8)

DOI: 10.1007/s11557-022-01816-x HZI-Repositorium

Kage F., Döring H., Mietkowska M., Schaks M., Grüner F., Stahnke S., Steffen A., Müsken M., ... , Stradal T.E.B., Rottner K. (2022)

Lamellipodia-like actin networks in cells lacking WAVE regulatory complex

J Cell Sci, 135 (15)

DOI: 10.1242/jcs.260364 HZI-Repositorium PubMed

Garcia K.Y.M., Quimque M.T.J., Lambert C., Schmidt K., Primahana G., Stradal T.E.B., Ratzenböck A., Dahse H.M., Phukhamsakda C., Stadler M., ... , Surup F., Macabeo A.P.G. (2022)

Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation

J.Fungi.(Basel), 8 (6)

DOI: 10.3390/jof8060560 HZI-Repositorium PubMed

Kirchenwitz M., Stahnke S., Prettin S., Borowiak M., Menke L., Sieben C., Birchmeier C., Rottner K., ... , Stradal T.E.B., Steffen A. (2022)

SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta

Cells, 11 (10)

DOI: 10.3390/cells11101648 HZI-Repositorium PubMed

Fung T.S., Chakrabarti R., Kollasser J., Rottner K., Stradal T.E.B., ... , Kage F., Higgs H.N. (2022)

Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria

Curr.Biol., 32 (7)

DOI: 10.1016/j.cub.2022.02.058 HZI-Repositorium PubMed

Rottner K., Stradal T.E.B. (2022)

WASP stings into matrix to lead immune cell migration

J.Cell Biol., 221 (2)

DOI: 10.1083/jcb.202112087 HZI-Repositorium PubMed

Rottner K., Stradal T.E.B., Chen B. (2021)

WAVE regulatory complex

Curr.Biol., 31 (10)

DOI: 10.1016/j.cub.2021.01.086 HZI-Repositorium PubMed

Lambert C., Pourmoghaddam M.J., Cedeno-Sanchez M., Surup F., Khodaparast S.A., Krisai-Greilhuber I., Voglmayr H., ... , Stradal T.E.B., Stadler M. (2021)

Resolution of the Hypoxylon fuscum complex (hypoxylaceae, xylariales) and discovery and biological characterization of two of its prominent secondary metabolites

J.Fungi, 7 (2)

DOI: 10.3390/jof7020131 HZI-Repositorium PubMed

Stahnke S., Döring H., Kusch C., De Gorter D.J.J., Dütting S., Guledani A., Pleines I., Schnoor M., Sixt M., Geffers R., Rohde M., Müsken M., Kage F., Steffen A., Faix J., Nieswandt B., ... , Rottner K., Stradal T.E.B. (2021)

Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion

Curr.Biol., 31 (5 / May)

DOI: 10.1016/j.cub.2021.02.043 HZI-Repositorium PubMed

Dimchev V., Lahmann I., Koestler S.A., Kage F., Dimchev G., Steffen A., Stradal T.E.B., Vauti F., ... , Arnold H.H., Rottner K. (2021)

Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation

Front.Cell Dev.Biol., 9

DOI: 10.3389/fcell.2021.634708 HZI-Repositorium PubMed

Leithner A., Altenburger L.M., Hauschild R., Assen F.P., Rottner K., Stradal T.E.B., Diz-Munoz A., ... , Stein J.V., Sixt M. (2021)

Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse

J.Cell Biol., 220 (4)

DOI: 10.1083/jcb.202006081 HZI-Repositorium PubMed

Chaoprasid P., Lukat P., Mühlen S., Heidler T., Gazdag E.M., Dong S., Bi W., Rüter C., Kirchenwitz M., Steffen A., Jänsch L., Stradal T.E.B., ... , Dersch P., Blankenfeldt W. (2021)

Crystal structure of bacterial cytotoxic necrotizing factor CNF g

EMBO J, 40 (4)

DOI: 10.15252/embj.2020105202 HZI-Repositorium PubMed

Felgner S., Preusse M., Beutling U., Stahnke S., Pawar V., Rohde M., Brönstrup M., ... , Stradal T., Häußler S. (2020)

Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake

Elife., 9 (September)

DOI: 10.7554/eLife.55744 HZI-Repositorium PubMed

Wang C., Lambert C., Hauser M., Deuschmann A., Zeilinger C., Rottner K., Stradal T.E.B., Stadler M., ... , Skellam E.J., Cox R.J. (2020)

Diversely Functionalised Cytochalasins through Mutasynthesis and Semi-Synthesis

Chem.Eur.J., 26 (60)

DOI: 10.1002/chem.202002241 HZI-Repositorium PubMed

Salzer E., Zoghi S., Kiss M.G., Kage F., Rashkova C., Stahnke S., Haimel M., Platzer R., Caldera M., Ardy R.C., Hoeger B., Block J., Medgyesi D., Sin C., Shahkarami S., Kain R., Ziaee V., Hammerl P., Bock C., Menche J., Dupré L., Huppa J.B., Sixt M., Lomakin A., Rottner K., Binder C.J., Stradal T.E.B., ... , Rezaei N., Boztug K. (2020)

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

Sci.Immunol., 5 (49)

DOI: 10.1126/sciimmunol.abc3979 HZI-Repositorium PubMed

Horstmann J.A., Lunelli M., Cazzola H., Heidemann J., Kühne C., Steffen P., Szefs S., Rossi C., Lokareddy R.K., Wang C., Lemaire L., Hughes K.T., Uetrecht C., Schlüter H., Grassl G.A., Stradal T.E.B., Rossez Y., ... , Kolbe M., Erhardt M. (2020)

Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion

Nat.Commun., 11 (1)

DOI: 10.1038/s41467-020-15738-3 HZI-Repositorium PubMed

Moussa A.Y., Lambert C., Stradal T.E.B., Ashrafi S., Maier W., ... , Stadler M., Helaly S.E. (2020)

New peptaibiotics and a cyclodepsipeptide from ijuhya vitellina: Isolation, identification, cytotoxic and nematicidal activities

Antibiotics, 9 (3)

DOI: 10.3390/antibiotics9030132 HZI-Repositorium PubMed

Dimchev G., Amiri B., Humphries A.C., Schaks M., Dimchev V., Stradal T.E.B., Faix J., Krause M., Way M., ... , Falcke M., Rottner K. (2020)

Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

J.Cell Sci., 133 (7)

DOI: 10.1242/jcs.239020 HZI-Repositorium PubMed

Kage F., Steffen A., Ellinger A., Ranftler C., Gehre C., Brakebusch C., Pavelka M., ... , Stradal T., Rottner K. (2019)

Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

Sci Rep., 9 (1)

DOI: 10.1038/s41598-019-54630-z HZI-Repositorium PubMed

Schaks M., Döring H., Kage F., Steffen A., Klünemann T., Blankenfeldt W., ... , Stradal T., Rottner K. (2021)

RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE regulatory complex-binding

Small Gtpases., 12 (2)

DOI: 10.1080/21541248.2019.1657755 HZI-Repositorium PubMed

Bense S., Bruchmann S., Steffen A., Stradal T.E.B., Häußler S., Düvel J. (2019)

Spatiotemporal control of FlgZ activity impacts Pseudomonas aeruginosa flagellar motility

Mol.Microbiol., 111 (6)

DOI: 10.1111/mmi.14236 HZI-Repositorium PubMed

Kretz R., Wendt L., Wongkanoun S., Luangsa-ard J.J., Surup F., Helaly S.E., Noumeur S.R., ... , Stadler M., Stradal T.E.B. (2019)

The Effect of Cytochalasans on the Actin Cytoskeleton of Eukaryotic Cells and Preliminary Structure(-)Activity Relationships

Biomolecules., 9 (2)

DOI: 10.3390/biom9020073 HZI-Repositorium PubMed

Franke R., Hinkelmann B., Fetz V., Stradal T., Sasse F., ... , Klawonn F., Brönstrup M. (2019)

xCELLanalyzer: A Framework for the Analysis of Cellular Impedance Measurements for Mode of Action Discovery

SLAS.Discov.

DOI: 10.1177/2472555218819459 HZI-Repositorium PubMed

Nauth T., Huschka F., Schweizer M., Bosse J.B., Diepold A., Failla A.V., Steffen A., Stradal T., ... , Wolters M., Aepfelbacher M. (2018)

Visualization of translocons in Yersinia type III protein secretion machines during host cell infection

PLoS.Pathog., 14 (12)

DOI: 10.1371/journal.ppat.1007527 HZI-Repositorium PubMed

Kluge F., Weissbach J., Weber A., Stradal T., Posern G. (2018)

Regulation of MRTF-A by JMY via a nucleation-independent mechanism

Cell Commun.Signal., 16 (1)

DOI: 10.1186/s12964-018-0299-x HZI-Repositorium PubMed

Schaks M., Singh S.P., Kage F., Thomason P., Klünemann T., Steffen A., Blankenfeldt W., Stradal T.E., ... , Insall R.H., Rottner K. (2018)

Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo

Curr.Biol., 28 (11)

DOI: 10.1016/j.cub.2018.10.002 HZI-Repositorium PubMed

Shlomovitz R., Schloen K., Stradal T., Gov N.S. (2013)

Cellular shapes from protrusive and adhesive forces

, 1 (9)

DOI: -

Stradal T.E.B., Schelhaas M. (2018)

Actin dynamics in host-pathogen interaction

FEBS Lett., 592 (22)

DOI: 10.1002/1873-3468.13173 HZI-Repositorium PubMed

Schnoor M., Stradal T.E., Rottner K. (2017)

Cortactin: Cell Functions of A Multifaceted Actin-Binding Protein

Trends Cell Biol., 28 (2)

DOI: 10.1016/j.tcb.2017.10.009 PubMed

Böttcher R.T., Veelders M., Rombaut P., Faix J., Theodosiou M., Stradal T.E., Rottner K., Zent R., ... , Herzog F., Fassler R. (2017)

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading

J.Cell Biol., 216 (11)

DOI: 10.1083/jcb.201701176 HZI-Repositorium

Litschko C., Linkner J., Bruhmann S., Stradal T.E.B., Reinl T., Jänsch L., ... , Rottner K., Faix J. (2017)

Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes

Eur.J.Cell Biol., 96 (8)

DOI: 10.1016/j.ejcb.2017.08.003 PubMed

Steffen A., Stradal T.E., Rottner K. (2017)

Signalling Pathways Controlling Cellular Actin Organization

Handb.Exp.Pharmacol., 235

DOI: 10.1007/164_2016_35 PubMed

Kage F., Steffen A., Ellinger A., Ranftler C., Gehre C., Brakebusch C., Pavelka M., ... , Stradal T., Rottner K. (2017)

FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

Sci.Rep., 7 (1)

DOI: 10.1038/s41598-017-09952-1 HZI-Repositorium PubMed

Stradal T.E.B., Wehland J. (2005)

Actin dynamics and WASP/WAVE proteins

Biospektrum, 11 (3)

DOI: -

Noumeur S.R., Helaly S.E., Jansen R., Gereke M., Stradal T.E., ... , Harzallah D., Stadler M. (2017)

Preussilides A-F, Bicyclic Polyketides from the Endophytic Fungus Preussia similis with Antiproliferative Activity

J.Nat.Prod., 80 (5)

DOI: 10.1021/acs.jnatprod.7b00064 HZI-Repositorium PubMed

Horstmann J.A., Zschieschang E., Truschel T., de Diego J., Lunelli M., Rohde M., May T., Strowig T., Stradal T., ... , Kolbe M., Erhardt M. (2017)

Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonization

Cell Microbiol., 19 (8)

DOI: 10.1111/cmi.12739 HZI-Repositorium PubMed

Kage F., Winterhoff M., Dimchev V., Mueller J., Thalheim T., Freise A., Bruhmann S., Kollasser J., Block J., Dimchev G., Geyer M., Schnittler H.J., Brakebusch C., Stradal T.E., Carlier M.F., Sixt M., Kas J., ... , Faix J., Rottner K. (2017)

FMNL formins boost lamellipodial force generation

Nat.Commun., 8

DOI: 10.1038/ncomms14832 HZI-Repositorium PubMed

Stradal T.E., Costa S.C. (2016)

Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics

Curr Top.Microbiol.Immunol. (35)

DOI: 10.1007/82_2016_35 PubMed

Leithner A., Eichner A., Muller J., Reversat A., Brown M., Schwarz J., Merrin J., de Gorter D.J., Schur F., Bayerl J., de Vries I, Wieser S., Hauschild R., Lai F.P., Moser M., Kerjaschki D., Rottner K., Small J.V., ... , Stradal T.E., Sixt M. (2016)

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes

Nat.Cell Biol., 18 (11)

DOI: 10.1038/ncb3426 HZI-Repositorium

Thiam H.R., Vargas P., Carpi N., Crespo C.L., Raab M., Terriac E., King M.C., Jacobelli J., Alberts A.S., Stradal T., ... , Lennon-Dumenil A.M., Piel M. (2016)

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

Nat.Commun., 7

DOI: 10.1038/ncomms10997 HZI-Repositorium PubMed

Rottner K., Stradal T.E.B. (2016)

How distinct Arp2/3 complex variants regulate actin filament assembly

Nat.Cell Biol., 18 (1)

DOI: 10.1038/ncb3293 HZI-Repositorium PubMed

Blasche S., Arens S., Ceol A., Siszler G., Schmidt M.A., Hauser R., Schwarz F., Wuchty S., Aloy P., Uetz P., ... , Stradal Theresia E.B., Koegl M. (2014)

The EHEC-host interactome reveals novel targets for the translocated intimin receptor

Scientific Reports, 4

DOI: 10.1038/srep07531 HZI-Repositorium PubMed

Schluter K., Waschbusch D., Anft M., Hugging D., Kind S., Hanisch J., Lakisic G., Gautreau A., ... , Barnekow A., Stradal Theresia E. (2014)

JMY is involved in anterograde vesicle trafficking from the trans-Golgi network

European Journal of Cell Biology, 93

DOI: 10.1016/j.ejcb.2014.06.001 HZI-Repositorium PubMed

Steffen A., Ladwein M., Dimchev G.A., Hein A., Schwenkmezger L., Arens S., Ladwein K.I., Holleboom J.M., Schur F., Small J.V., Schwarz J., Gerhard R., Faix J., Stradal Theresia E.B., ... , Brakebusch C., Rottner K. (2013)

Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

Journal of Cell Science, 126 (20)

DOI: 10.1242/jcs.118232 HZI-Repositorium PubMed

Koestler S.A., Steffen A., Nemethova M., Winterhoff M., Luo N., Holleboom J.Margit, Krupp J., Jacob S., Vinzenz M., Schur F., Schluter K., Gunning P.W., Winkler C., Schmeiser C., Faix J., Stradal T.E., ... , Small J.V., Rottner K. (2013)

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin1

Molecular Biology of the Cell, 24 (18)

DOI: 10.1091/mbc.E12-12-0857 HZI-Repositorium PubMed

Block J., Breitsprecher D., Kuhn S., Winterhoff M., Kage F., Geffers R., Duwe P., Rohn J.L., Baum B., Brakebusch C., Geyer M., Stradal T.E., ... , Faix J., Rottner K. (2012)

FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

Current biology, 22 (11)

DOI: 10.1016/j.cub.2012.03.064 HZI-Repositorium PubMed

Hanisch J., Stradal T.E., Rottner K. (2012)

A novel contractility pathway operating in Salmonella invasion

Virulence, 3 (1)

Rottner K., Stradal T.E. (2011)

Actin dynamics and turnover in cell motility

Current Opinion in Cell Biology, 23 (5)

de Groot J.C., Schluter K., Carius Y., Quedenau C., Vingadassalom D., Faix J., Weiss S.M., Reichelt J., Standfuss-Gabisch C., Lesser C.F., Leong J.M., Heinz Dirk W.*, ... , Büssow Konrad*, Stradal Theresia E.* (2011)

Structural Basis for Complex Formation between Human IRSp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. coli

Structure, 19 (9)

DOI: 10.1016/j.str.2011.06.015 HZI-Repositorium PubMed

Linkner J., Witte G., Stradal Theresia*, Curth U., Faix J. (2011)

High-Resolution X-Ray Structure of the Trimeric Scar/WAVE-Complex Precursor Brk1

PLoS ONE, 6 (6)

DOI: 10.1371/journal.pone.0021327 HZI-Repositorium PubMed

Kabaso D., Shlomovitz R., Schloen K., Stradal Theresia*, Gov N.S. (2011)

Theoretical model for cellular shapes driven by protrusive and adhesive forces

PLoS Computational Biology, 7 (5)

DOI: 10.1371/journal.pcbi.1001127 HZI-Repositorium PubMed

Oelkers J.M., Vinzenz M., Nemethova M., Jacob S., Lai F.P., Block J., Szczodrak M., Kerkhoff E., Backert S., Schluter K., Stradal T.E., Small J.V., ... , Koestler S.A., Rottner K. (2011)

Microtubules as platforms for assaying actin polymerization in vivo

PLoS ONE, 6 (5)

DOI: 10.1371/journal.pone.0019931 HZI-Repositorium PubMed

Dubielecka P.M., Ladwein K.I., Xiong X., Migeotte I., Chorzalska A., Anderson K.V., Sawicki J.A., Rottner K., ... , Stradal T.E., Kotula L. (2011)

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

Proceedings of the National Academy of Sciences USA, 108 (17)

DOI: 10.1073/pnas.1016811108 HZI-Repositorium PubMed

Hänisch J., Kolm R., Wozniczka M., Bumann D., Rottner K., Stradal T.E. (2011)

Activation of a RhoA/Myosin II-Dependent but Arp2/3 Complex-Independent Pathway Facilitates Salmonella Invasion

Cell Host and Microbe, 9 (4)

Breitsprecher D., Kiesewetter A.K., Linkner J., Vinzenz M., Stradal Theresia E.*, Small J.V., Curth U., ... , Dickinson R.B., Faix J. (2011)

Molecular mechanism of Ena/VASP-mediated actin-filament elongation

Embo Journal, 30 (3)

DOI: 10.1038/emboj.2010.348 HZI-Repositorium PubMed

Stradal Theresia B.*, Backert S. (2010)

Host-pathogen interaction: How EHEC influence the actin cytoskeleton of the host cell [Wirt-Pathogen-Interaktion wie EHEC das Aktinzytoskelett der Wirtszelle beeinflussen]

Biospektrum, 16 (6)

Horn J., Wang X., Reichardt P., Stradal Theresia E.*, Warnecke N., Simeoni L., Gunzer Matthias*, Yablonski D., ... , Schraven B., Kliche S. (2009)

Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells

Journal of Immunology, 183 (9)

Tahirovic S., Hellal F., Neukirchen D., Hindges R., Garvalov B.K., Flynn K.C., Stradal Theresia E.*, Chrostek-Grashoff A., ... , Brakebusch C., Bradke F. (2010)

Rac1 regulates neuronal polarization through the WAVE complex

Journal of Neuroscience, 30 (20)

DOI: 10.1523/JNEUROSCI.5395-09.2010 HZI-Repositorium PubMed

Klink B.U., Barden S., Heidler T.V., Borchers C., Ladwein M., Stradal T.B., ... , Rottner K., Heinz D.W. (2010)

Structure of Shigella IpgB2 in complex with human RhoA: implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry

Journal of Biological Chemistry, 285 (22)

DOI: 10.1074/jbc.M110.107953 HZI-Repositorium PubMed

Hänisch J., Ehinger J., Ladwein M., Rohde M., Derivery E., Bosse T., Steffen A., Bumann D., Misselwitz B., Hardt W.D., Gautreau A., ... , Stradal T.E., Rottner K. (2010)

Molecular dissection of Salmonella-induced membrane ruffling versus invasion

Cellular Microbiology, 12 (1)

DOI: 10.1111/j.1462-5822.2009.01380.x HZI-Repositorium PubMed

Rottner K., Stradal Theresia E.* (2009)

Poxviruses taking a ride on actin: new users of known hardware

Cell Host and Microbe, 6 (6)

Giuliani C., Troglio F., Bai Z., Patel F.B., Zucconi A., Malabarba M.G., Disanza A., Stradal Theresia B.*, Cassata G., Confalonieri S., Hardin J.D., Soto M.C., ... , Grant B.D., Scita G. (2009)

Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis

PLoS Genetics, 5 (10)

Lai F.P., Szczodrak M., Oelkers J.M., Ladwein M., Acconcia F., Benesch S., Auinger S., Faix J., Small J.V., Polo S., ... , Stradal T.E., Rottner K. (2009)

Cortactin Promotes Migration and PDGF-induced Actin Reorganization by Signaling to Rho-GTPases

Molecular Biology of the Cell, 20 (14)

Stradal Theresia E.* (2008)

The regulation of cellular protrusions

Zellbiologie Aktuell, 34

Faix J., Breitsprecher D., Stradal T.E.B., Rottner K. (2009)

Filopodia: Complex models for simple rods

The International Journal of Biochemistry and Cell Biology, 41 (8-9)

DOI: 10.1016/j.biocel.2009.02.012 HZI-Repositorium PubMed

Weiss S.M., Ladwein M., Schmidt D., Ehinger J., Lommel S., Städing K., Beutling U., Disanza A., Frank R., Jänsch L., Scita G., Gunzer F., ... , Rottner K., Stradal T.E. (2009)

IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation

Cell Host and Microbe, 5 (3)

Block J., Stradal T.E.B., Hanisch J., Geffers R., Kostler S.A., Urban E., Small J.V., ... , Rottner K., Faix J. (2008)

Filopodia formation induced by active mDia2/Drf3

Journal of Microscopy, 231 (3)

DOI: 10.1111/j.1365-2818.2008.02063.x HZI-Repositorium PubMed

Beutling U., Stading K., Stradal Theresia E.B.*, Frank Ronald* (2008)

Large-scale analysis of protein-protein interactions using cellulose-bound peptide arrays

Advances in Biochemical Engineering/Biotechnology, 110

DOI: 10.1007/10_2008_096 HZI-Repositorium PubMed

Derivery E., Fink J., Martin D., Houdusse A., Piel M., Stradal Theresia E.B.*, ... , Louvard D., Gautreau A. (2008)

Free Brick1 is a trimeric precursor in the assembly of a functional wave complex

PLoS ONE, 3 (6)

DOI: 10.1371/journal.pone.0002462 HZI-Repositorium PubMed

Lai F.P.L., Szczodrak M., Block J., Faix J., Breitsprecher D., Mannherz H.G., Stradal Theresia E.B.*, Dunn G.A., ... , Small J.V., Rottner C. (2008)

Arp2/3 complex interactions and actin network turnover in lamellipodia

The EMBO Journal, 27 (7)

DOI: 10.1242/jcs.02822 HZI-Repositorium PubMed

Bosse T., Ehinger J., Czuchra A., Benesch S., Steffen A., Wu X., Schloen K., Niemann H.H., Scita G., Stradal T.E.B., ... , Brakebusch C., Rottner K. (2007)

Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways

Molecular and Cellular Biology, 27 (19)

DOI: 10.1128/MCB.00367-07 HZI-Repositorium PubMed

Ménasché G., Kliche S., Chen E.J., Stradal Theresia E.B.*, Schraven B., Koretzky G. (2007)

RIAM links the ADAP/SKAP-55 signaling module to Rap1 facilitating TCR-mediated integrin activation

Molecular and Cellular Biology, 27

Chmielowiec J., Borowiak M., Morkel M., Stradal Theresia E.B.*, Munz B., Werner S., Wehland Jürgen*, ... , Birchmeier Carmen, Birchmeier Walter (2007)

c-Met is essential for wound healing in the skin

Journal of Cell Biology, 177 (1)

DOI: 10.1083/jcb.200701086 HZI-Repositorium PubMed

Stradal Theresia E.B.*, Pusch R., Kliche S. (2006)

Molecular regulation of cytoskeletal rearrangements during T cell signalling

Disanza A., Mantoani S., Hertzog M., Gerboth S., Frittoli E., Steffen A., Berhoerster K., Kreienkamp H.J., Milanesi F., Di Fiore P.P., Ciliberto A., ... , Stradal Theresia E.B.*, Scita G. (2006)

Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex

Nature Cell Biology, 8 (12)

Rottner K., Kaverina I.N., Stradal Theresia E.B.* (2006)

Cytoskeleton proteins

, 3rd

Frese S., Schubert Wolf-Dieter*, Findeis A.C., Marquardt T., Roske Y.S., ... , Stradal Theresia E.B.*, Heinz Dirk W.* (2006)

Phosphotyrosine binding specificities of Nck1 and Nck2

Journal of Biological Chemistry, 281

Steffen A., Faix J., Resch G.P., Linkner J., Wehland J., Small J.V., ... , Rottner K., Stradal T.E.B. (2006)

Filopodia formation in the absence of functional WAVE- and Arp2/3-complex

Molecular Biology of the Cell, 17

DOI: 10.1091/mbc.E05-11-1088 HZI-Repositorium PubMed

Schirenbeck A., Arasada R., Bretschneider T., Stradal Theresia E.B.*, Schleicher M., Faix J. (2006)

The bunding activity of vasodilator-stimulated phosphoprotein is required for filopodium formation

Proceedings of the National Academy of Sciences of the United States of America, 103

Stradal T.E.B., Scita G. (2006)

Protein complexes regulating cellular actin assembly

Current Opinion in Cell Biology, 8

Stradal T.E.B., Wehland J. (2005)

Aktindynamik und WASP/WAVE-Proteine/Actin dynamics and WASP/WAVE proteins

Biospektrum, 11

Innocenti M., Gerboth S., Rottner K., Lai Frank P.L., Hertzog M., Stradal T.E.B., Frittoli E., Didry D., Polo S., Disanza A., Benesch S., Di Fiore P.P., ... , Carlier M.-F., Scita G. (2005)

Abi1regulates the activity of N-WASP and WAVE in distinct actin-based processes

Nature Cell Biology, 7 (10)

Benesch S., Polo S., Lai F.P.L., Anderson K.I., Stradal T.E.B., ... , Wehland J., Rottner K. (2005)

N-WASP deficiency impairs EGF internalization and actin assembly at clathrin coated pits

Journal of Cell Science, 118

DOI: 10.1242/jcs.02444 PubMed

Rottner K., Stradal T.E.B., Wehland J. (2005)

Bacteria - host cell interactions at the plasma membrane: stories on actin cytoskeleton subversion

Developmental Cell, 9

Chandrasekar I., Stradal T.E.B., Holt M.R., Entschladen F., Jockusch B.M., Ziegler W.H. (2005)

Vinculin acts as a sensor in lipid regulation of adhesion-site turnover

Journal of Cell Science, 118

DOI: 10.1242/jcs.01734 HZI-Repositorium

Dubois T., Paleotti O., Mironov A.A., Fraisier V., Stradal T.E.B., De Matteis M.A., ... , Franco M., Chavrier P. (2005)

Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics

Nature Cell Biology, 7 (4)

Jenzora A., Behrendt B., Small J.V., Wehland J., Stradal T.E.B. (2005)

PREL1 links Ras signalling to actin remodeling via Ena/VASP proteins

Febs Letters, 579

Stradal T.E.B., Lommel S., Wehland J., Rottner K. (2005)

Host-pathogen interactions and cell motility: learning from bacteria

(12)

Disanza A., Carlier M.F., Stradal T.E.B., Didry D., Frittoli E., Confalonieri S., Croce A., Wehland J., ... , DiFiore P.P., Scita G. (2004)

Eps8 controls actin-based motility by capping the barbed ends of actin filaments

Nature Cell Biology, 6

Rottner K., Lommel S., Wehland J., Stradal T.E.B. (2004)

Pathogen-induced actin filament rearrangement in infectious diseases

Journal of Pathology, 204

Pacholsky D., Himmel M., Löw T., Stradal T.E.B., Rottner K., ... , Fürst D.O., Van der Ven P.F. (2004)

Xin repeats define a novel actin binding motif

Journal of Cell Science, 117

Stradal T.E.B., Rottner K., Disanza A., Confalonieri S., Innocenti M., Scita G. (2004)

Regulation of actin dynamics by WASF and WAVE family proteins

Trends in Cell Biology, 14

Innocenti M., Zucconi A., Disanza A., Frittoli E., Areces L., Steffen A., Stradal T.E.B., Di Fiore P.P., ... , Carlier M.F., Scita G. (2004)

Abi1 is essential for the formation and activation of a WAVE2 signaling complex mediating Rac-dependent actin remodeling

Nature Cell Biology, 6

Steffen A., Rottner K., Ehinger J., Innocenti M., Scita G., ... , Wehland J., Stradal T.E.B. (2004)

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation

Embo Journal, 23 (4)

Stradal T.B., Sechi A.S., Wehland J., Rottner K. (2003)

The cytoskeleton

Kaverina I., Stradal T.E.B., Gimona M. (2003)

Prodosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains

Journal of Cell Science, 116

Small J.V., Stradal T., Vignal E., Rottner K. (2002)

The lamellipodium: Where motility begins.

Trends in Cell Biology, 12

Benesch S., Lommel S., Steffen A., Stradal T.E., Scaplehorn N., Way M., ... , Wehland J., Rottner K. (2002)

Phosphatidylinositol 4,5-Biphosphate (PIP2)-induced Vesicle Movement Depends on N-WASP and Involves Nck, WIP, and Grb2*210

Journal of Biological Chemistry, 277 (40)

DOI: 10.1074/jbc.M204145200 PubMed

Stradal T.B., Courtney K., Rottner K., Hahne P., Small J.V., Pendergast A.M. (2001)

The Abl-interactor (Abi) proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.

Current biology, 11

Stradal T.B., Troxler H., Heizmann C.W., Gimona M. (2000)

Mapping the zinc ligands of S100A2 by site-directed mutagenesis

Journal of Biological Chemistry, 275

Prof. Dr. Theresia Stradal

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