Prof. Dr. Till Strowig

Osbelt L., Almasi E.D.H., Wende M., Kienesberger S., Voltz A., Lesker T.R., Muthukumarasamy U., Knischewski N., Nordmann E., Bielecka A.A., Giralt-Zuniga M., Kaganovitch E., Kühne C., Baier C., Pietsch M., Müsken M., Greweling-Pils M.C., Breinbauer R., Flieger A., Schlüter D., Müller R., Erhardt M., ... , Zechner E.L., Strowig T. (2024)

Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms

Nat.Microbiol.

DOI: 10.1038/s41564-024-01710-0 HZI-Repositorium PubMed

Büssing R., Bublitz A., Karge B., Brönstrup M., Strowig T., Ott I. (2024)

An organometallic hybrid antibiotic of metronidazole with a Gold(I) N-Heterocyclic Carbene overcomes metronidazole resistance in Clostridioides difficile

J.Biol.Inorg.Chem.

DOI: 10.1007/s00775-024-02064-y HZI-Repositorium PubMed

Neumann C., Blume J., Roy U., Teh P.P., Vasanthakumar A., Beller A., Liao Y., Heinrich F., Arenzana T.L., Hackney J.A., Eidenschenk C., G+ílvez E.J.C., Stehle C., Heinz G.A., Maschmeyer P., Sidwell T., Hu Y., Amsen D., Romagnani C., Chang H.D., Kruglov A., Mashreghi M.F., Shi W., Strowig T., Rutz S., ... , Kallies A., Scheffold A. (2024)

Correction to: c-Maf-dependent T(reg) cell control of intestinal T(H)17 cells and IgA establishes host-microbiota homeostasis (Nature Immunology, (2019), 20, 4, (471-481), 10.1038/s41590-019-0316-2)

Nature Immunology

DOI: 10.1038/s41590-024-01863-4 PubMed

Vialetto E., Miele S., Goren M.G., Yu J., Yu Y., Collias D., Beamud B., Osbelt L., Lourenco M., Strowig T., Brisse S., Barquist L., Qimron U., ... , Bikard D., Beisel C.L. (2024)

Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide-and strain-dependent features influencing antimicrobial activity

Nucleic Acids Res.

DOI: 10.1093/nar/gkae281 HZI-Repositorium PubMed

Klee B., Diexer S., Horn J., Langer S., Wende M., Ortiz D., Bielecka A., Strowig T., ... , Mikolajczyk R., Gottschick C. (2024)

The impact of non-pharmaceutical interventions on community non-SARS-CoV-2 respiratory infections in preschool children

BMC Pediatrics, 24 (1)

DOI: 10.1186/s12887-024-04686-2 HZI-Repositorium PubMed

Zou M., Pezoldt J., Mohr J., Philipsen L., Leufgen A., Cerovic V., Wiechers C., Pils M., Ortiz D., Hao L., Yang J., Beckstette M., Dupont A., Hornef M., Dersch P., Strowig T., Müller A.J., ... , Raila J., Huehn J. (2024)

Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes

Cell Reports, 43 (5)

DOI: 10.1016/j.celrep.2024.114153 HZI-Repositorium PubMed

Almasi E.D.H., Knischewski N., Osbelt L., Muthukumarasamy U., el Mouali Y., Vialetto E., ... , Beisel C.L., Strowig T. (2024)

An adapted method for Cas9-mediated editing reveals the species-specific role of b

J.Bacteriol.

DOI: 10.1128/jb.00317-23 PubMed

Huang K.D., Amend L., Galvez E.J.C., Lesker T.R., de Oliveira R., Bielecka A., Blanco-Miguez A., Valles-Colomer M, Ruf I, Pasolli E, Buer J, Segata N, Esser S, ... , Strowig T, Kehrmann J (2024)

Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices

Cell Rep.Med.

DOI: 10.1016/j.xcrm.2024.101426 HZI-Repositorium PubMed

Kerlikowsky F., Müller M., Greupner T., Amend L., Strowig T., Hahn A. (2023)

Distinct Microbial Taxa Are Associated with LDL-Cholesterol Reduction after 12 Weeks of Lactobacillus plantarum Intake in Mild Hypercholesterolemia: Results of a Randomized Controlled Study

Probiotics Antimicrob.Proteins

DOI: 10.1007/s12602-023-10191-2 HZI-Repositorium PubMed

Tsakmaklis A., Farowski F., Zenner R., Lesker T.R., Strowig T., Schlößer H., Lehmann J., von Bergwelt-Baildon M., Mauch C., Schlaak M., Knuever J., Schweinsberg V., ... , Heinzerling L.M., Vehreschild M.J.G.T. (2023)

TIGIT+ NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients

BMC Cancer, 23 (1)

DOI: 10.1186/s12885-023-11551-5 HZI-Repositorium PubMed

Blanco-Miguez A., Galvez E.J.C., Pasolli E., De Filippis F., Amend L., Huang K.D., Manghi P., Lesker T.R., Riedel T., Cova L., Puncoochar M., Thomas A.M., Valles-Colomer M., Schober I., Hitch T.C.A., Clavel T., Berry S.E., Davies R., Wolf J., Spector T.D., Overmann J., Tett A., Ercolini D., ... , Segata N., Strowig T. (2023)

Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions

Cell Host.Microbe, 31 (11)

DOI: 10.1016/j.chom.2023.09.013 HZI-Repositorium PubMed

Ma J., Urgard E., Runge S., Classon C.H., Mathä L., Stark J.M., Cheng L., Alvarez J.A., von Zedtwitz S., Baleviciute A., Martinez Hoyer S., Li M., Gernand A.M., Osbelt L., Bielecka A.A., Lesker T.R., Huang H.J., Vrtala S., Boon L., Beyaert R., Adner M., Martinez Gonzalez I., Strowig T., Du J., Nylen S., ... , Rosshart S.P., Coquet J.M. (2023)

Laboratory mice with a wild microbiota generate strong allergic immune responses

Sci Immunol, 8 (87)

DOI: 10.1126/sciimmunol.adf7702 HZI-Repositorium PubMed

Hamad I., Van Broeckhoven J., Cardilli A., Hellings N., Strowig T., Lemmens S., ... , Hendrix S., Kleinewietfeld M. (2023)

Effects of Recombinant IL-13 Treatment on Gut Microbiota Composition and Functional Recovery after Hemisection Spinal Cord Injury in Mice

Nutrients, 15 (19)

DOI: 10.3390/nu15194184 HZI-Repositorium PubMed

Siracusa F., Schaltenberg N., Kumar Y., Lesker T.R., Steglich B., Liwinski T., Cortesi F., Frommann L., Diercks B.P., B+Ânisch F., Fischer A.W., Scognamiglio P., Pauly M.J., Casar C., Cohen Y., Pelczar P., Agalioti T., Delfs F., Worthmann A., Wahib R., Jagemann B., Mittr++cker H.W., Kretz O., Guse A.H., Izbicki J.R., Lassen K.G., Strowig T., Schweizer M., Villablanca E.J., Elinav E., Huber S., ... , Heeren J., Gagliani N. (2023)

Short-term dietary changes can result in mucosal and systemic immune depression

Nat.Immunol., 24 (9)

DOI: 10.1038/s41590-023-01587-x HZI-Repositorium PubMed

Essex M., Rios Rodriguez V, Rademacher J., Proft F., Löber U., Marko L., Pleyer U., Strowig T., Marchand J., Kirwan J.A., Siegmund B., ... , Forslund S.K., Poddubnyy D. (2023)

Spondyloarthritis, acute anterior uveitis, and Crohn's disease have both shared and distinct gut microbiota

Arthritis Rheumatol.

DOI: 10.1002/art.42658 PubMed

Harnack C., Berger H., Liu L., Mollenkopf H.J., Strowig T., Sigal M. (2023)

Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis

Gut Microbes, 15 (1)

DOI: 10.1080/19490976.2023.2233689 HZI-Repositorium PubMed

Liu X., Khalil A.E.M.M., Muthukumarasamy U., Onogi Y., Yan X., Singh I., Lopez-Gonzales E., Israel A., Serrano A.C., ... , Strowig T., Ussar S. (2023)

Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice

BMC Biol., 21 (1)

DOI: 10.1186/s12915-023-01629-8 HZI-Repositorium PubMed

Li D., Bühler M., Runft S., Gerold G., Marek K., Baumgärtner W., ... , Strowig T., Gerhauser I. (2023)

ASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler's murine encephalomyelitis virus

Sci.Rep., 13 (1)

DOI: 10.1038/s41598-023-38152-3 HZI-Repositorium PubMed

Saleh D.O., Horstmann J.A., Giralt-Zuniga M., Weber W., Kaganovitch E., Durairaj A.C., Klotzsch E., ... , Strowig T., Erhardt M. (2023)

SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner

PLoS.Pathog., 19 (6)

DOI: 10.1371/journal.ppat.1011451 HZI-Repositorium PubMed

Lourenco M., Osbelt L., Passet V., Gravey F., Megrian D., Strowig T., ... , Rodrigues C., Brisse S. (2023)

Phages against Noncapsulated Klebsiella pneumoniae: Broader Host range, Slower Resistance

Microbiol.Spectr.

DOI: 10.1128/spectrum.04812-22 HZI-Repositorium PubMed

Gui W., Hole M.J., Molinaro A., Edlund K., Jorgensen K.K., Su H., Begher-Tibbe B., Gaßler N., Schneider C.V., Muthukumarasamy U., Mohs A., Liao L., Jaeger J., Mertens C.J., Bergheim I., Strowig T., Hengstler J.G., Hov J.R., Marschall H.U., ... , Trautwein C., Schneider K.M. (2023)

Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis

Nat.Commun., 14 (1)

DOI: 10.1038/s41467-023-38840-8 HZI-Repositorium PubMed

Paschold L., Gottschick C., Langer S., Klee B., Diexer S., Aksentijevich I., Schultheiß C., Purschke O., Riese P., Trittel S., Haase R., Dressler F., Eberl W., Hübner J., Strowig T., Guzman C.A., ... , Mikolajczyk R., Binder M. (2023)

T cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort

Sci.Rep., 13 (1)

DOI: 10.1038/s41598-023-36144-x HZI-Repositorium

Zhao B., Osbelt L., Lesker T.R., Wende M., Galvez E.J.C., Hönicke L., Bublitz A., Greweling-Pils M.C., Grassl G.A., ... , Neumann-Schaal M., Strowig T. (2023)

Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacterrodentium infection in the absence of adaptive immunity

Cell Rep., 42 (6)

DOI: 10.1016/j.celrep.2023.112549 HZI-Repositorium PubMed

Fuchs M., Lamm-Schmidt V., Lence T., Sulzer J., Bublitz A., Wackenreuter J., Gerovac M., ... , Strowig T., Faber F. (2023)

A network of small RNAs regulates sporulation initiation in Clostridioides difficile

EMBO J

DOI: 10.15252/embj.2022112858 HZI-Repositorium PubMed

Manghi P., Blanco-Miguez A., Manara S., NabiNejad A., Cumbo F., Beghini F., Armanini F., Golzato D., Huang K.D., Thomas A.M., Piccinno G., Puncochar M., Zolfo M., Lesker T.R., Bredon M., Planchais J., Glodt J., Valles-Colomer M., Koren O., Pasolli E., Asnicar F., Strowig T., ... , Sokol H., Segata N. (2023)

MetaPhlAn 4 profiling of unknown species-level genome bins improves the characterization of diet-associated microbiome changes in mice

Cell Rep., 42 (5)

DOI: 10.1016/j.celrep.2023.112464 HZI-Repositorium PubMed

Bublitz A., Brauer M., Wagner S., Hofer W., Müsken M., Deschner F., Lesker T.R., Neumann-Schaal M., Paul L., Nübel U., Bartel J., Kany A.M., Zühlke D., Bernecker S., Jansen R., Sievers S., Riedel K., Herrmann J., Müller R., ... , Fuchs T.M., Strowig T. (2023)

The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection

Cell Host.Microbe

DOI: 10.1016/j.chom.2023.04.003 HZI-Repositorium PubMed

Su H., Haque M., Becker S., Edlund K., Duda J., Wang Q., Marschall H.U., Candels L.S., Mohamed M., Sj+Âland W., Liao L., Drexler S.A., Strowig T., Rahnenführer J., ... , Hengstler J.G., Hatting M. (2023)

Long-term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals

Liver International

DOI: 10.1111/liv.15587 HZI-Repositorium PubMed

Gilbert B.T.P., Lamacchia C., Amend L., Strowig T., Rodriguez E., ... , Palmer G., Finckh A. (2023)

Brief report: Assessment of mucosal barrier integrity using serological biomarkers in preclinical stages of rheumatoid arthritis

Front.Immunol., 14

DOI: 10.3389/fimmu.2023.1117742 HZI-Repositorium PubMed

Tintelnot J., Xu Y., Lesker T.R., Schönlein M., Konczalla L., Giannou A.D., Pelczar P., Kylies D., Puelles V.G., Bielecka A.A., Peschka M., Cortesi F., Riecken K., Jung M., Amend L., Bröring T.S., Trajkovic-Arsic M., Siveke J.T., Renné T., Zhang D., Boeck S., Strowig T., Uzunoglu F.G., Güngör C., Stein A., Izbicki J.R., Bokemeyer C., Sinn M., Kimmelman A.C., ... , Huber S., Gagliani N. (2023)

Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

Nature

DOI: 10.1038/s41586-023-05728-y HZI-Repositorium PubMed

Amend L., Gilbert B.T.P., Pelczar P., Böttcher M., Huber S., Witte T., ... , Finckh A., Strowig T. (2023)

Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases

Front.Cell.Infect.Microbiol., 12

DOI: 10.3389/fcimb.2022.1096211 HZI-Repositorium PubMed

Collias D., Vialetto E., Yu J., Co K., Almasi E., Rüttiger A.S., Achmedov T., ... , Strowig T., Beisel C.L. (2023)

Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria

Nat.Commun., 14 (1)

DOI: 10.1038/s41467-023-36283-9 HZI-Repositorium PubMed

Giannou A.D., Kempski J., Shiri A.M., Lücke J., Zhang T., Zhao L., Zazara D.E., Cortesi F., Riecken K., Amezcua Vesely M.C., Low J.S., Xu H., Kaffe E., Garcia-Perez L., Agalioti T., Yamada Y., Jungraithmayr W., Zigmond E., Karstens K.F., Steglich B., Wagner J., Konczalla L., Carambia A., Schulze K., von Felden J., May P., Briukhovetska D., Bedke T., Brockmann L., Starzonek S., Lange T., Koch C., Riethdorf S., Pelczar P., Böttcher M., Sabihi M., Huber F.J., Reeh M., Grass J.K., Wahib R., Seese H., Stüben B.O., Fard-Aghaie M., Duprée A., Scognamiglio P., Plitzko G., Meiners J., Soukou S., Wittek A., Manthey C., Maroulis I.C., Arck P.C., Perez D., Gao B., Zarogiannis S.G., Strowig T., Pasqualini R., Arap W., Gosálvez J.S., Kobold S., Prinz I., Guse A.H., Tachezy M., Ghadban T., Heumann A., Li J., Melling N., Mann O., Izbicki J.R., Pantel K., Schumacher U., Lohse A.W., Flavell R.A., ... , Gagliani N., Huber S. (2023)

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

Immunity, 56 (1)

DOI: 10.1016/j.immuni.2022.12.014 HZI-Repositorium PubMed

Hankel J., Sander S., Muthukumarasamy U., Strowig T., Kamphues J., ... , Jung K., Visscher C. (2022)

Microbiota of vaccinated and non-vaccinated clinically inconspicuous and conspicuous piglets under natural Lawsonia intracellularis infection

Front.Vet.Sci., 9

DOI: 10.3389/fvets.2022.1004506 HZI-Repositorium PubMed

Thriene K., Stanislas V., Amend L., Strowig T., Michels K.B. (2022)

Assessment of the Gut Microbiota during Juice Fasting with and without Inulin Supplementation: A Feasibility Study in Healthy Volunteers

Foods, 11 (22)

DOI: 10.3390/foods11223673 HZI-Repositorium PubMed

Riese P., Trittel S., Akmatov M.K., May M., Prokein J., Illig T., Schindler C., Sawitzki B., Elfaki Y., Floess S., Huehn J., Blazejewski A.J., Strowig T., Hernandez-Vargas E.A., Geffers R., Zhang B., Li Y., ... , Pessler F., Guzmán C.A. (2022)

Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-34487-z HZI-Repositorium PubMed

Hankel J., Kittler S., Chuppava B., Galvez E., Strowig T., Becker A., Von Köckritz-Blickwede M., ... , Plötz M., Visscher C. (2022)

Luminal and mucosa-associated caecal microbiota of chickens after experimental Campylobacter jejuni infection in the absence of Campylobacter-specific phages of group II and III

Microb.Genomics, 8 (10)

DOI: 10.1099/mgen.0.000874 HZI-Repositorium PubMed

Afrizal A., Jennings S.A.V., Hitch T.C.A., Riedel T., Basic M., Panyot A., Treichel N., Hager F.T., Wong E.O., Wolter B., Viehof A., von Strempel A., Eberl C., Buhl E.M., Abt B., Bleich A., Tolba R., Blank L.M., Navarre W.W., Kiessling F., Horz H.P., Torow N., Cerovic V., Stecher B., Strowig T., ... , Overmann J., Clavel T. (2022)

Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities

Cell Host.Microbe

DOI: 10.1016/j.chom.2022.09.011 HZI-Repositorium PubMed

Hankel J., Chuppava B., Wilke V., Hartung C.B., Muthukumarasamy U., Strowig T., Bach Knudsen K.E., ... , Kamphues J., Visscher C. (2022)

High Dietary Intake of Rye Affects Porcine Gut Microbiota in a Salmonella Typhimurium Infection Study

Plants, 11 (17)

DOI: 10.3390/plants11172232 HZI-Repositorium PubMed

Hitch T.C.A., Bisdorf K., Afrizal A., Riedel T., Overmann J., ... , Strowig T., Clavel T. (2022)

A taxonomic note on the genus Prevotella: Description of four novel genera and emended description of the genera Hallella and Xylanibacter

Syst.Appl.Microbiol., 45 (6)

DOI: 10.1016/j.syapm.2022.126354 HZI-Repositorium PubMed

Pausder A., Mras P., Hoenicke L., Waldburg N., Lesker T.R., Schreiber J., Strowig T., ... , Boehme J.D., Bruder D. (2022)

Altered nasal microbiota in asthmatic patients is not related to changes in secretory immunity in the nasopharynx

Clin.Exp.Allergy

DOI: 10.1111/cea.14200 HZI-Repositorium PubMed

French T., Steffen J., Glas A., Osbelt L., Strowig T., Schott B.H., ... , Schüler T., Dunay I.R. (2022)

Persisting Microbiota and Neuronal Imbalance Following T. gondii Infection Reliant on the Infection Route

Front.Immunol., 13

DOI: 10.3389/fimmu.2022.920658 HZI-Repositorium PubMed

Melcher C., Yu J., Duong V.H.H., Westphal K., Helmi Siasi Farimany N., Shaverskyi A., Zhao B., Strowig T., Glage S., Brand K., Chan A.C., ... , Föger N., Lee K.H. (2022)

B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation

Cell Rep., 40 (2)

DOI: 10.1016/j.celrep.2022.111051 HZI-Repositorium PubMed

Schneider K.M., Mohs A., Gui W., Galvez E.J.C., Candels L.S., Hoenicke L., Muthukumarasamy U., Holland C.H., Elfers C., Kilic K., Schneider C.V., Schierwagen R., Strnad P., Wirtz T.H., Marschall H.U., Latz E., Lelouvier B., Saez-Rodriguez J., de Vos W., Strowig T., ... , Trebicka J., Trautwein C. (2022)

Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment

Nat.Commun., 13 (1)

DOI: 10.1038/s41467-022-31312-5 HZI-Repositorium PubMed

Lucassen A., Hankel J., Finkler-Schade C., Osbelt L., Strowig T., ... , Visscher C., Schuberth H.J. (2022)

Feeding a Saccharomyces cerevisiae Fermentation Product (Olimond BB) Does Not Alter the Fecal Microbiota of Thoroughbred Racehorses

Animals.(Basel), 12 (12)

DOI: 10.3390/ani12121496 HZI-Repositorium PubMed

Meyer F., Fritz A., Deng Z.L., Koslicki D., Lesker T.R., Gurevich A., Robertson G., Alser M., Antipov D., Beghini F., Bertrand D., Brito J.J., Brown C.T., Buchmann J., Buluc A., Chen B., Chikhi R., Clausen P.T.L.C., Cristian A., Dabrowski P.W., Darling A.E., Egan R., Eskin E., Georganas E., Goltsman E., Gray M.A., Hansen L.H., Hofmeyr S., Huang P., Irber L., Jia H., Jorgensen T.S., Kieser S.D., Klemetsen T., Kola A., Kolmogorov M., Korobeynikov A., Kwan J., LaPierre N., Lemaitre C., Li C., Limasset A., Malcher-Miranda F., Mangul S., Marcelino V.R., Marchet C., Marijon P., Meleshko D., Mende D.R., Milanese A., Nagarajan N., Nissen J., Nurk S., Oliker L., Paoli L., Peterlongo P., Piro V.C., Porter J.S., Rasmussen S., Rees E.R., Reinert K., Renard B., Robertsen E.M., Rosen G.L., Ruscheweyh H.J., Sarwal V., Segata N., Seiler E., Shi L., Sun F., Sunagawa S., Sorensen S.J., Thomas A., Tong C., Trajkovski M., Tremblay J., Uritskiy G., Vicedomini R., Wang Z., Warren A., Willassen N.P., Yelick K., You R., Zeller G., Zhao Z., Zhu S., Zhu J., Garrido-Oter R., Gastmeier P., Hacquard S., Häussler S., Khaledi A., Maechler F., Mesny F., Radutoiu S., Schulze-Lefert P., Smit N., Strowig T., Bremges A., ... , Sczyrba A., McHardy A.C. (2022)

Critical Assessment of Metagenome Interpretation: the second round of challenges

Nature Methods, 19 (4)

DOI: 10.1038/s41592-022-01431-4 HZI-Repositorium PubMed

Kini A., Zhao B., Basic M., Roy U., Iljazovic A., Odak I., Ye Z., Riederer B., Di Stefano G., Römermann D., Koenecke C., Bleich A., ... , Strowig T., Seidler U. (2022)

Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect

Gut Microbes, 14 (1)

DOI: 10.1080/19490976.2022.2041943 HZI-Repositorium PubMed

Pausder A., Fricke J., Schughart K., Schreiber J., Strowig T., ... , Bruder D., Boehme J.D. (2021)

Exogenous and Endogenous Triggers Differentially Stimulate Pigr Expression and Antibacterial Secretory Immunity in the Murine Respiratory Tract

Lung

DOI: 10.1007/s00408-021-00498-8 HZI-Repositorium PubMed

Li J., Gálvez E.J.C., Amend L., Almasi A., Iljazovic A., Lesker T.R., Bielecka A.A., ... , Schorr E.M., Strowig T. (2021)

A versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems

Embo Journal, 40 (23)

DOI: 10.15252/embj.2021108287 HZI-Repositorium PubMed

Muschaweck M., Kopplin L., Ticconi F., Schippers A., Iljazovic A., Galvez E.J.C., Abdallah A.T., Wagner N., Costa I.G., ... , Strowig T., Pabst O. (2021)

Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon

Immunity.

DOI: 10.1016/j.immuni.2021.08.014 HZI-Repositorium PubMed

Osbelt L., Wende M., Almasi A., Derksen E., Muthukumarasamy U., Lesker T.R., Galvez E.J.C., Pils M.C., Schalk E., Chhatwal P., Farber J., Neumann-Schaal M., Fischer T., ... , Schlüter D., Strowig T. (2021)

Klebsiella oxytoca causes colonization resistance against multidrug-resistant K.Â pneumoniae in the gut via cooperative carbohydrate competition

Cell Host.Microbe

DOI: 10.1016/j.chom.2021.09.003 HZI-Repositorium PubMed

Schneider K.M., Candels L.S., Hov J.R., Myllys M., Hassan R., Schneider C.V., Wahlström A., Mohs A., Zühlke S., Liao L., Elfers C., Kilic K., Henricsson M., Molinaro A., Hatting M., Zaza A., Drasdo D., Frissen M., Devlin A.S., Gálvez E.J.C., Strowig T., Karlsen T.H., Hengstler J.G., Marschall H.U., ... , Ghallab A., Trautwein C. (2021)

Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling

Nature Meta., 3 (9)

DOI: 10.1038/s42255-021-00452-1 PubMed

Roy U., de Oliveira R.S., Galvez E.J.C., Gronow A., Basic M., Perez L.G., Gagliani N., Bleich A., ... , Huber S., Strowig T. (2021)

Induction of IL-22-Producing CD4+ T Cells by Segmented Filamentous Bacteria Independent of Classical Th17 Cells

Front.Immunol., 12

DOI: 10.3389/fimmu.2021.671331 HZI-Repositorium PubMed

Plaza-Sirvent C., Zhao B., Bronietzki A.W., Pils M.C., Tafrishi N., Schuster M., ... , Strowig T., Schmitz I. (2021)

A Central Role for Atg5 in Microbiota-Dependent Foxp3(+) RORg[gamma]t(+) Treg Cell Preservation to Maintain Intestinal Immune Homeostasis

Front Immunol., 12

DOI: 10.3389/fimmu.2021.705436 HZI-Repositorium PubMed

Hankel J., Bodmann B., Todte M., Galvez E., Strowig T., Radko D., ... , Antakli A., Visscher C. (2021)

Comparison of Chicken Cecal Microbiota after Metaphylactic Treatment or Following Administration of Feed Additives in a Broiler Farm with Enterococcal Spondylitis History

Pathogens., 10 (8)

DOI: 10.3390/pathogens10081068 HZI-Repositorium PubMed

Delacher M., Simon M., Sanderink L., Hotz-Wagenblatt A., Wuttke M., Schambeck K., Schmidleithner L., Bittner S., Pant A., Ritter U., Hehlgans T., Riegel D., Schneider V., Groeber-Becker F.K., Eigenberger A., Gebhard C., Strieder N., Fischer A., Rehli M., Hoffmann P., Edinger M., Strowig T., Hühn J., Schmidl C., Werner J.M., Prantl L., Brors B., ... , Imbusch C.D., Feuerer M. (2021)

Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

Immunity, 54 (4)

DOI: 10.1016/j.immuni.2021.03.007 HZI-Repositorium PubMed

Maifeld A., Bartolomaeus H., Löber U., Avery E.G., Steckhan N., Markó L., Wilck N., Hamad I., Susnjar U., Mähler A., Hohmann C., Chen C.Y., Cramer H., Dobos G., Lesker T.R., Strowig T., Dechend R., Bzdok D., Kleinewietfeld M., Michalsen A., ... , Müller D.N., Forslund S.K. (2021)

Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients

Nat Commun., 12 (1)

DOI: 10.1038/s41467-021-22097-0 HZI-Repositorium PubMed

Wiechers C., Zou M., Galvez E., Beckstette M., Ebel M., Strowig T., ... , Huehn J., Pezoldt J. (2021)

The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes

Cell Mol.Immunol., 18 (5)

DOI: 10.1038/s41423-021-00647-2 HZI-Repositorium PubMed

Song Y., Shan L., Gbyli R., Liu W., Strowig T., Patel A., Fu X., Wang X., Xu M.L., Gao Y., Qin A., Bruscia E.M., Tebaldi T., Biancon G., Mamillapalli P., Urbonas D., Eynon E., Gonzalez D.G., Chen J., Krause D.S., Alderman J., ... , Halene S., Flavell R.A. (2021)

Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells

Science, 371 (6533)

DOI: 10.1126/science.abe2485 HZI-Repositorium PubMed

Schneider K.M., Elfers C., Ghallab A., Schneider C.V., Galvez E.J.C., Mohs A., Gui W., Candels L.S., Wirtz T.H., Zuehlke S., Spiteller M., Myllys M., Roulet A., Ouzerdine A., Lelouvier B., Kilic K., Liao L., Nier A., Latz E., Bergheim I., Thaiss C.A., Hengstler J.G., ... , Strowig T., Trautwein C. (2021)

Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury

Cell.Mol.Gastroenterol.Hepatol., 11 (4)

DOI: 10.1016/j.jcmgh.2020.11.002 HZI-Repositorium PubMed

Regen T., Isaac S., Amorim A., Nunez N.G., Hauptmann J., Shanmugavadivu A., Klein M., Sankowski R., Mufazalov I.A., Yogev N., Huppert J., Wanke F., Witting M., Grill A., Gálvez E.J.C., Nikolaev A., Blanfeld M., Prinz I., Schmitt-Kopplin P., Strowig T., Reinhardt C., Prinz M., Bopp T., Becher B., ... , Ubeda C., Waisman A. (2021)

IL-17 controls central nervous system autoimmunity through the intestinal microbiome

Sci.Immunol., 6 (56)

DOI: 10.1126/sciimmunol.aaz6563 HZI-Repositorium PubMed

Iljazovic A., Amend L., Galvez E.J.C., de Oliveira R., Strowig T. (2021)

Modulation of inflammatory responses by gastrointestinal Prevotella spp. - From associations to functional studies

Int.J.Med.Microbiol., 311 (2)

DOI: 10.1016/j.ijmm.2021.151472 HZI-Repositorium PubMed

Koeninger L., Osbelt L., Berscheid A., Wendler J., Berger J., Hipp K., Lesker T.R., Pils M.C., Malek N.P., Jensen B.A.H., Brötz-Oesterhelt H., ... , Strowig T., Wehkamp J. (2021)

Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota

Commun.Biolog., 4 (1)

DOI: 10.1038/s42003-020-01582-0 HZI-Repositorium PubMed

Wylensek D., Hitch T.C.A., Riedel T., Afrizal A., Kumar N., Wortmann E., Liu T., Devendran S., Lesker T.R., Hernández S.B., Heine V., Buhl E.M., D'Agostino M., Cumbo F., Fischöder T., Wyschkon M., Looft T., Parreira V.R., Abt B., Doden H.L., Ly L., Alves J.M.P., Reichlin M., Flisikowski K., Suarez L.N., Neumann A.P., Suen G., de Wouters T., Rohn S., Lagkouvardos I., len-Vercoe E., Spröer C., Bunk B., Taverne-Thiele A.J., Giesbers M., Wells J.M., Neuhaus K., Schnieke A., Cava F., Segata N., Elling L., Strowig T., Ridlon J.M., Gulder T.A.M., ... , Overmann J., Clavel T. (2020)

A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity

Nat.Commun., 11 (1)

DOI: 10.1038/s41467-020-19929-w HZI-Repositorium PubMed

Wells P.M., Adebayo A.S., Bowyer R.C.E., Freidin M.B., Finckh A., Strowig T., Lesker T.R., Apizar-Rodriguez D., Gilbert B., Kirkham B., Cope A.P., ... , Steves C.J., Williams F.M.K. (2020)

Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study

Lancet Rheumatol., 2 (7)

DOI: 10.1016/S2665-9913(20)30064-3 HZI-Repositorium PubMed

Galvez E.J.C., Iljazovic A., Amend L., Lesker T.R., Renault T., Thiemann S., Hao L., Roy U., Gronow A., ... , Charpentier E., Strowig T. (2020)

Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp

Cell Host.Microbe, 28 (6)

DOI: 10.1016/j.chom.2020.09.012 HZI-Repositorium PubMed

Dürholz K., Hofmann J., Iljazovic A., Häger J., Lucas S., Sarter K., Strowig T., Bang H., Rech J., ... , Schett G., Zaiss M.M. (2020)

Dietary short-term fiber interventions in arthritis patients increase systemic scfa levels and regulate inflammation

Nutrients, 12 (10)

DOI: 10.3390/nu12103207 HZI-Repositorium PubMed

Wilharm A., Brigas H.C., Sandrock I., Ribeiro M., Amado T., Reinhardt A., Demera A., Hoenicke L., Strowig T., Carvalho T., ... , Prinz I., Ribot J.C. (2020)

Correction: Microbiota-dependent expansion of testicular IL-17-producing Vg[gamma]6(+) g[gamma]d[delta]T cells upon puberty promotes local tissue immune surveillance

Mucosal.Immunol., 14 (1)

DOI: 10.1038/s41385-020-00346-7 HZI-Repositorium PubMed

Hankel J., El-Wahab A.A., Grone R., Keller B., Galvez E., ... , Strowig T., Visscher C. (2020)

Faecal microbiota of dogs offered a vegetarian diet with or without the supplementation of feather meal and either cornmeal, rye or fermented rye: A preliminary study

Microorg., 8 (9)

DOI: 10.3390/microorganisms8091363 HZI-Repositorium PubMed

Wilharm A., Brigas H.C., Sandrock I., Ribeiro M., Amado T., Reinhardt A., Demera A., Hoenicke L., Strowig T., Carvalho T., ... , Prinz I., Ribot J.C. (2020)

Microbiota-dependent expansion of testicular IL-17-producing Vg[gamma]6+ g[gamma]d[delta] T cells upon puberty promotes local tissue immune surveillance

Mucosal Immunol., 14 (1)

DOI: 10.1038/s41385-020-0330-6 HZI-Repositorium PubMed

Kempski J., Giannou A.D., Riecken K., Zhao L., Steglich B., Lücke J., Garcia-Perez L., Karstens K.F., Wöstemeier A., Nawrocki M., Pelczar P., Witkowski M., Nilsson S., Konczalla L., Shiri A.M., Kempska J., Wahib R., Brockmann L., Huber P., Gnirck A.-C., Turner J.-E., Zazara D.E., Arck P.C., Stein A., Simon R., Daubmann A., Meiners J., Perez D., Strowig T., Koni P., Kruglov A.A., Sauter G., Izbicki J.R., Guse A.H., Roesch T., Lohse A.W., Flavell R.A., ... , Gagliani N., Huber S. (2020)

IL22BP Mediates the Anti-Tumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans

Gastroenterology, 159 (4)

DOI: 10.1053/j.gastro.2020.06.033 HZI-Repositorium PubMed

Iljazovic A., Roy U., Gálvez E.J.C., Lesker T.R., Zhao B., Gronow A., Amend L., Will S.E., Hofmann J.D., Pils M.C., Schmidt-Hohagen K., ... , Neumann-Schaal M., Strowig T. (2020)

Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation

Mucosal.Immunol., 14 (1)

DOI: 10.1038/s41385-020-0296-4 HZI-Repositorium PubMed

Carriche G.M., Almeida L., Stüve P., Velasquez L., Dhillon-LaBrooy A., Roy U., Lindenberg M., Strowig T., Plaza-Sirvent C., Schmitz I., Lochner M., ... , Simon A.K., Sparwasser T. (2021)

Regulating T cell differentiation through the polyamine spermidine

J.Allergy Clin.Immunol., 147 (1)

DOI: 10.1016/j.jaci.2020.04.037 PubMed

Bunte S., Grone R., Keller B., Keller C., Galvez E., Strowig T., ... , Kamphues J., Hankel J. (2020)

Intestinal microbiota of fattening pigs offered non-fermented and fermented liquid feed with and without the supplementation of non-fermented coarse cereals

Microorg., 8 (5)

DOI: 10.3390/microorganisms8050638 HZI-Repositorium PubMed

Tajik N., Frech M., Schulz O., Schalter F., Lucas S., Azizov V., Durholz K., Steffen F., Omata Y., Rings A., Bertog M., Rizzo A., Iljazovic A., Basic M., Kleyer A., Culemann S., Kronke G., Luo Y., Uberla K., Gaipl U.S., Frey B., Strowig T., Sarter K., Bischoff S.C., Wirtz S., Canete J.D., Ciccia F., ... , Schett G., Zaiss M.M. (2020)

Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

Nat.Commun., 11 (1)

DOI: 10.1038/s41467-020-15831-7 HZI-Repositorium PubMed

Roje B., Elek A., Palada V., Bom J., Iljazovic A., Simic A., Susak L., Vilovic K., Strowig T., ... , Vlahovicek K., Terzic J. (2020)

Microbiota Alters Urinary Bladder Weight and Gene Expression

Microorganisms., 8 (3)

DOI: 10.3390/microorganisms8030421 HZI-Repositorium PubMed

Osbelt L., Thiemann S., Smit N., Lesker T.R., Schröter M., Galvez E.J.C., Schmidt-Hohagen K., Pils M.C., Mühlen S., Dersch P., Hiller K., Schluter D., ... , Neumann-Schaal M., Strowig T. (2020)

Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production

PLoS.Pathog., 16 (3)

DOI: 10.1371/journal.ppat.1008448 HZI-Repositorium PubMed

Lesker T.R., Durairaj A.C., Gálvez E.J.C., Lagkouvardos I., Baines J.F., Clavel T., Sczyrba A., ... , McHardy A.C., Strowig T. (2020)

An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome

Cell Rep., 30 (9)

DOI: 10.1016/j.celrep.2020.02.036 HZI-Repositorium PubMed

Bank U., Deiser K., Plaza-Sirvent C., Osbelt L., Witte A., Knop L., Labrenz R., Jänsch R., Richter F., Biswas A., Zenclussen A.C., Vivier E., Romagnani C., Kühl A.A., Dunay I.R., Strowig T., ... , Schmitz I., Schüler T. (2020)

c-FLIP is crucial for IL-7/IL-15-dependent NKp46(+) ILC development and protection from intestinal inflammation in mice

Nat.Commun., 11 (1)

DOI: 10.1038/s41467-020-14782-3 HZI-Repositorium PubMed

Al-Kershi S., Bhayadia R., Ng M., Verboon L., Emmrich S., Gack L., Schwarzer A., Strowig T., ... , Heckl D., Klusmann J.H. (2019)

The stem cell-specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia

Blood Adv., 3 (24)

DOI: 10.1182/bloodadvances.2019032029 HZI-Repositorium PubMed

Alpizar Rodriguez D., Lesker T.R., Gilbert B., Strowig T., Finckh A. (2021)

Response to: 'Non-causal association of gut microbiome on the risk of rheumatoid arthritis: a Mendelian randomisation study' by Inamo

Ann.Rheum.Dis., 80 (7)

DOI: 10.1136/annrheumdis-2019-216637 HZI-Repositorium PubMed

Wiesenborn D.S., Galvez E.J.C., Spinel L., Victoria B., Allen B., Schneider A., Gesing A., Al-Regaiey K.A., Strowig T., ... , Schäfer K.H., Masternak M.M. (2020)

The role of Ames dwarfism and calorie restriction on gut microbiota

J.Gerontol.A Biol.Sci.Med.Sci., 75 (7)

DOI: 10.1093/gerona/glz236 HZI-Repositorium PubMed

Hankel J., Jung K., Kuder H., Keller B., Keller C., Galvez E., ... , Strowig T., Visscher C. (2019)

Caecal Microbiota of Experimentally Campylobacter jejuni-Infected Chickens at Different Ages

Front Microbiol., 10

DOI: 10.3389/fmicb.2019.02303 HZI-Repositorium PubMed

Lipinski S., Pfeuffer S., Arnold P., Treitz C., Aden K., Ebsen H., Falk-Paulsen M., Gisch N., Fazio A., Kuiper J., Luzius A., Billmann-Born S., Schreiber S., Nunez G., Beer H.D., Strowig T., Lamkanfi M., ... , Tholey A., Rosenstiel P. (2019)

Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles

EMBO J., 38 (20)

DOI: 10.15252/embj.2018101266 HZI-Repositorium PubMed

Strowig T., Thiemann S., Diefenbach A. (2018)

Microbiome and gut immunity: Innate immune cells

(8)

DOI: 10.1007/978-3-319-90545-7_8 PubMed

Liao L., Schneider K.M., Galvez E.J.C., Frissen M., Marschall H.U., Su H., Hatting M., Wahlström A., Haybaeck J., Puchas P., Mohs A., Peng J., Bergheim I., Nier A., Hennings J., Reissing J., Zimmermann H.W., Longerich T., Strowig T., Liedtke C., ... , Cubero F.J., Trautwein C. (2019)

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

GUT, 68 (8)

DOI: 10.1136/gutjnl-2018-316670 PubMed

Visscher C., Hankel J., Nies A., Keller B., Galvez E., Strowig T., ... , Keller C., Breves G. (2019)

Performance, Fermentation Characteristics and Composition of the Microbiome in the Digest of Piglets Kept on a Feed With Humic Acid-Rich Peat

Front Vet.Sci., 6 (Febrary)

DOI: 10.3389/fvets.2019.00029 HZI-Repositorium

Mamareli P., Kruse F., Friedrich C., Smit N., Strowig T., ... , Sparwasser T., Lochner M. (2019)

Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile

Eur.J.Immunol, 49 (5)

DOI: 10.1002/eji.201848022

Neumann C., Blume J., Roy U., Teh P.P., Vasanthakumar A., Beller A., Liao Y., Heinrich F., Arenzana T.L., Hackney J.A., Eidenschenk C., Gálvez E.J.C., Stehle C., Heinz G.A., Maschmeyer P., Sidwell T., Hu Y., Amsen D., Romagnani C., Chang H.D., Kruglov A., Mashreghi M.F., Shi W., Strowig T., Rutz S., ... , Kallies A., Scheffold A. (2019)

c-Maf-dependent T reg cell control of intestinal T H 17 cells and IgA establishes host-microbiota homeostasis

Nat.Immunol.

DOI: 10.1038/s41590-019-0316-2 PubMed

Lagkouvardos I., Lesker T.R., Hitch T.C.A., Gálvez E.J.C., Smit N., Neuhaus K., Wang J., Baines J.F., Abt B., Stecher B., Overmann J., ... , Strowig T., Clavel T. (2019)

Sequence and cultivation study of Muribaculaceae reveals novel species, host preference, and functional potential of this yet undescribed family

Microbiome, 7 (1)

DOI: 10.1186/s40168-019-0637-2 HZI-Repositorium PubMed

Alpizar-Rodriguez D., Lesker T.R., Gronow A., Gilbert B., Raemy E., Lamacchia C., Gabay C., ... , Finckh A., Strowig T. (2019)

Prevotella copri in individuals at risk for rheumatoid arthritis

Ann.Rheum.Dis., 78 (5)

DOI: 10.1136/annrheumdis-2018-214514 HZI-Repositorium PubMed

Mathies F., Steffens N., Kleinschmidt D., Stuhlmann F., Huber F.J., Roy U., Meyer T., Luetgehetmann M., von Petersdorff M., Seiz O., Herkel J., Schramm C., Flavell R.A., Gagliani N., Krebs C., Panzer U., Abdullah Z., Strowig T., ... , Bedke T., Huber S. (2018)

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3(+) Regulatory T Cells

J.Immunol., 201 (12)

DOI: 10.4049/jimmunol.1800711

Pezoldt J., Pasztoi M., Zou M., Wiechers C., Beckstette M., Thierry G.R., Vafadarnejad E., Floess S., Arampatzi P., Buettner M., Schweer J., Fleissner D., Vital M., Pieper D.H., Basic M., Dersch P., Strowig T., Hornef M., Bleich A., Bode U., Pabst O., Bajenoff M., ... , Saliba A.E., Hühn J. (2018)

Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes

Nat.Commun., 9 (1)

DOI: 10.1038/s41467-018-06423-7 HZI-Repositorium

Kindt A., Liebisch G., Clavel T., Haller D., Hörmannsperger G., Yoon H., Kolmeder D., Sigruener A., Krautbauer S., Seeliger C., Ganzha A., Schweizer S., Morisset R., Strowig T., Daniel H., Helm D., Küster B., ... , Krumsiek J., Ecker J. (2018)

The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice

Nat.Commun., 9 (1)

DOI: 10.1038/s41467-018-05767-4

Suwandhi L., Hausmann S., Braun A., Gruber T., Heinzmann S.S., Gálvez E.J.C., Buck A., Legutko B., Israel A., Feuchtinger A., Haythorne E., Staiger H., Heni M., Häring H.-U., Schmitt-Kopplin P., Walch A., Cáceres C.G., Tschöp M.H., Rutter G.A., Strowig T., ... , Elsner M., Ussar S. (2018)

Chronic D-serine supplementation impairs insulin secretion

Molecular Metabolism, 15 (September)

DOI: 10.1016/j.molmet.2018.07.002 HZI-Repositorium PubMed

Just S., Mondot S., Ecker J., Wegner K., Rath E., Gau L., Streidl T., Hery-Arnaud G., Schmidt S., Lesker T.R., Bieth V., Dunkel A., Strowig T., Hofmann T., Haller D., Liebisch G., ... , Rohn S., Lepage P. (2018)

The gut microbiota drives the impact of bile acids and fat source in diet on mouse metabolism

Microbiome, 6 (1)

DOI: 10.1186/s40168-018-0510-8 HZI-Repositorium PubMed

Schneider K.M., Wirtz T.H., Kroy D., Albers S., Neumann U.P., Strowig T., ... , Sellge G., Trautwein C. (2018)

Successful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation

Case.Rep.Gastroenterol., 12 (1)

DOI: 10.1159/000481937 HZI-Repositorium PubMed

Elinav E., Henao-Mejia J., Strowig T., Flavell R. (2018)

NLRP6 and Dysbiosis: Avoiding the Luring Attraction of Over-Simplification

Immunity, 48 (4)

DOI: 10.1016/j.immuni.2018.04.002 HZI-Repositorium PubMed

Heine W., Beckstette M., Heroven A.K., Thiemann S., Heise U., Nuss A.M., Pisano F., ... , Strowig T., Dersch P. (2018)

Loss of CNFY toxin-induced inflammation drives Yersinia pseudotuberculosis into persistency

PLoS.Pathog., 14 (2)

DOI: 10.1371/journal.ppat.1006858 HZI-Repositorium

Galvez E.J.C., Iljazovic A., Gronow A., Flavell R., Strowig T. (2017)

Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure

Cell Rep., 21 (13)

DOI: 10.1016/j.celrep.2017.12.027 HZI-Repositorium PubMed

Lucas S., Omata Y., Hofmann J., Bottcher M., Iljazovic A., Sarter K., Albrecht O., Schulz O., Krishnacoumar B., Kronke G., Herrmann M., Mougiakakos D., Strowig T., ... , Schett G., Zaiss M.M. (2018)

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

Nat.Commun., 9 (1)

DOI: 10.1038/s41467-017-02490-4 HZI-Repositorium

Herndler-Brandstetter D., Shan L., Yao Y., Stecher C., Plajer V., Lietzenmayer M., Strowig T., de Zoete M.R., Palm N.W., Chen J., Blish C.A., Frleta D., Gurer C., Macdonald L.E., Murphy A.J., Yancopoulos G.D., ... , Montgomery R.R., Flavell R.A. (2017)

Humanized mouse model supports development, function, and tissue residency of human natural killer cells

Proc.Natl.Acad.Sci.U.S.A., 114 (45)

DOI: 10.1073/pnas.1705301114 HZI-Repositorium PubMed

Roy U., Gàlvez E.J.C., Iljazovic A., Lesker T.R., Blazejewski A.J., Pils M.C., Heise U., Huber S., ... , Flavell R.A., Strowig T. (2017)

Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells

Cell Reports, 21 (4)

DOI: 10.1016/j.celrep.2017.09.097 HZI-Repositorium PubMed

Fabiani F.D., Renault T.T., Peters B., Dietsche T., Galvez E.J.C., Guse A., Freier K., Charpentier E., Strowig T., Franz-Wachtel M., Macek B., Wagner S., ... , Hensel M., Erhardt M. (2017)

A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum

PLoS Biol., 15 (8)

DOI: 10.1371/journal.pbio.2002267 HZI-Repositorium

Blazejewski A.J., Thiemann S., Schenk A., Pils M.C., Galvez E.J.C., Roy U., Heise U., de Zoete M.R., ... , Flavell R.A., Strowig T. (2017)

Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation

Cell Rep., 19 (11)

DOI: 10.1016/j.celrep.2017.05.058 HZI-Repositorium PubMed

Thiemann S., Smit N., Roy U., Lesker T.R., Galvez E.J.C., Helmecke J., Basic M., Bleich A., Goodman A.L., Kalinke U., Flavell R.A., ... , Erhardt M., Strowig T. (2017)

Enhancement of IFNgamma Production by Distinct Commensals Ameliorates Salmonella-Induced Disease

Cell Host.Microbe, 21 (6)

DOI: 10.1016/j.chom.2017.05.005 HZI-Repositorium PubMed

Friedrich C., Mamareli P., Thiemann S., Kruse F., Wang Z., Holzmann B., Strowig T., ... , Sparwasser T., Lochner M. (2017)

MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium

PLoS Pathog., 13 (5)

DOI: 10.1371/journal.ppat.1006357 HZI-Repositorium PubMed

Rueckert C., Rand U., Roy U., Kasmapour B., Strowig T., Guzmán C.A. (2017)

Cyclic dinucleotides modulate induced type I IFN responses in innate immune cells by degradation of STING

FASEB J., 31 (7)

DOI: 10.1096/fj.201601093R PubMed

Yu H., Borsotti C., Schickel J.N., Zhu S., Strowig T., Eynon E.E., Frleta D., Gurer C., Murphy A.J., Yancopoulos G.D., Meffre E., ... , Manz M.G., Flavell R.A. (2017)

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production

Blood, 129 (8)

DOI: 10.1182/blood-2016-04-709584 HZI-Repositorium PubMed

Horstmann J.A., Zschieschang E., Truschel T., de Diego J., Lunelli M., Rohde M., May T., Strowig T., Stradal T., ... , Kolbe M., Erhardt M. (2017)

Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonization

Cell Microbiol., 19 (8)

DOI: 10.1111/cmi.12739 HZI-Repositorium PubMed

Hu B., Jin C., Li H.B., Tong J., Ouyang X., Cetinbas N.M., Zhu S., Strowig T., Lam F.C., Zhao C., Henao-Mejia J., Yilmaz O., Fitzgerald K.A., Eisenbarth S.C., ... , Elinav E., Flavell R.A. (2016)

The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury

Science, 354 (6313)

DOI: 10.1126/science.aaf7532 HZI-Repositorium PubMed

Pelczar P., Witkowski M., Perez L.G., Kempski J., Hammel A.G., Brockmann L., Kleinschmidt D., Wende S., Haueis C., Bedke T., Witkowski M., Krasemann S., Steurer S., Booth C.J., Busch P., König A., Rauch U., Benten D., Izbicki J.R., Rösch T., Lohse A.W., Strowig T., Gagliani N., ... , Flavell R.A., Huber S. (2016)

A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease

Science, 354 (6310)

DOI: 10.1126/science.aah5903 PubMed

Thiemann S., Smit N., Strowig T. (2016)

Antibiotics and the Intestinal Microbiome : Individual Responses, Resilience of the Ecosystem, and the Susceptibility to Infections

Curr Top.Microbiol.Immunol., 398 (6)

DOI: 10.1007/82_2016_504 PubMed

Rausch P., Basic M., Batra A., Bischoff S.C., Blaut M., Clavel T., Glasner J., Gopalakrishnan S., Grassl G.A., Gunther C., Haller D., Hirose M., Ibrahim S., Loh G., Mattner J., Nagel S., Pabst O., Schmidt F., Siegmund B., Strowig T., Volynets V., Wirtz S., Zeissig S., Zeissig Y., ... , Bleich A., Baines J.F. (2016)

Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities

Int.J Med.Microbiol., 306 (5)

DOI: 10.1016/j.ijmm.2016.03.004 HZI-Repositorium PubMed

Finethy R., Jorgensen I., Haldar A.K., de Zoete M.R., Strowig T., Flavell R.A., Yamamoto M., Nagarajan U.M., ... , Miao E.A., Coers J. (2015)

Guanylate Binding Proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages

Infect.Immun., 83

DOI: 10.1128/IAI.00856-15 HZI-Repositorium PubMed

Wynosky-Dolfi M.A., Snyder A.G., Philip N.H., Doonan P.J., Poffenberger M.C., Avizonis D., Zwack E.E., Riblett A.M., Hu B., Strowig Till, Flavell R.A., Jones R.G., ... , Freedman B.D., Brodsky I.E. (2014)

Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome

Journal of Experimental Medicine, 211 (4)

Prof. Dr. Till Strowig

Publikationen

Forschungsgruppe

Standort

Social Media