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Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses cause in humans, bats generally do not show obvious signs of viral illness following infection. An international research team led by Dr. Max Kellner and Prof. Josef Penninger, Scientific Director of the Helmholtz Centre for Infection Research (HZI), has developed an innovative organoid research platform that allowed them to closely investigate the cellular antiviral defense mechanisms of mucosal epithelial tissues of bats. The results have now been published in Nature Immunology and could pave the way for the development of new therapies against viral diseases.

21.05.2025

HZI Campus

News

Yesterday, the biomedical project forge of the state of Lower Saxony reviewed the most promising ideas from across the region and selected the winners: At the fourth portfolio conference of the Institute for Biomedical Translation (IBT) Lower Saxony, a high-caliber jury selected projects from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, the University Medical Center Göttingen (UMG) and TWINCORE - Centre for Experimental and Clinical Infection Research, which will receive funding of almost 3 million euros. TWINCORE is a joint institution of the HZI and Hannover Medical School (MHH). A total of 25 million euros will be available to the IBT Lower Saxony until 2028 to accelerate the transfer of cutting-edge research in the life sciences in Lower Saxony and bring it to the world in the form of start-ups and entrepreneurial ideas.

14.05.2025

HZI Campus

TWINCORE

CiiM

Analysis of natural products using liquid chromatography.

News

Natural products are among the most promising candidates for the development of new drugs. However, due to their structural complexity, they are often difficult to access. A team headed by Tobias Gulder from the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has now developed new synthetic strategies for the class of polycyclic tetramate macrolactams (PoTeMs), a group of natural products with a broad spectrum of biological activities. In addition to chemical synthesis, enzymatic catalysis and genetic engineering approaches were used. The strategies established in this way not only allow PoTeMs to be produced in large quantities, but also to modify their carbon structure and thus their pharmaceutical properties. The researchers published their results in the journal Angewandte Chemie International Edition, among others.

12.05.2025

HIPS

News

Influenza viruses are among the most likely triggers of future pandemics. A research team from the Helmholtz Centre for Infection Research (HZI) and the Medical Center - University of Freiburg has developed a method that can be used to study the interaction of viruses with host cells in unprecedented detail. With the help of their new development, they have also analyzed how novel influenza viruses use alternative receptors to enter target cells. The results were recently published in two papers in the journal Nature Communications.

07.05.2025

HZI Campus

News

The Helmholtz Centre for Infection Research (HZI) has a lot to offer its doctoral candidates: Together with renowned partner institutions, the center has developed high-quality doctoral programs that impart in-depth expertise in innovative future disciplines and train the specialists of tomorrow. In addition to a first-class scientific education at one of the leading health research institutions, young scientists at HZI have the opportunity to expand their interdisciplinary knowledge and gain valuable additional skills in areas such as management and soft skills.

30.04.2025

HZI Campus

CiiM

HIRI

TWINCORE

HIPS

News

Every two years, the MDPI Sustainability Foundation presents the Tu Youyou Award for outstanding achievements in the fields of natural product and medicinal chemistry. This year, Rolf Müller is one of two researchers to receive the award for his work on developing new antibiotics based on microbial natural products. The prize was established in 2016 in honor of Chinese Nobel Prize winner Tu Youyou and comes with a total prize money of 100,000 Swiss francs.

30.04.2025

HIPS

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HZI in the media

... “, sagte die Leiterin der Epidemiologie am Braunschweiger Helmholtz-Zentrum für Infektionsforschung.

Lange betonte, flächendeckende ...

28.11.2025

Evangelische Zeitung

... ein Zentrum für Quantentechnologie entstehen und das Helmholtz-Institut für Pharmazeutische Forschung ausgebaut werden.

Mehr ...

27.11.2025

Tagesschau

Euro werden investiert in die Erweiterung des Helmholtz-Instituts für Pharmazeutische Forschung Saarland (HIPS). Und ...

27.11.2025

ZEIT online

s drug tolcapone. HIPS is a site of the Helmholtz Center for Infection Research (HZI) in collaboration with Saarland University.

The

26.11.2025

Medical Xpress

... erhielt das Projekt „Citrapeutics“ vom Helmholtz-Zentrum für Infektionsforschung (HZI) in Braunschweig eine Förderung in Höhe ...

25.11.2025

Bionity.COM

led by Hannover Medical School (MHH) and the Helmholtz Center for Infection Research (HZI) has now discovered clear molecular signatures for

24.11.2025

Medical Xpress

Medizinischen Hochschule Hannover (MHH) und dem Helmholtz-Zentrum für Infektionsforschung (HZI), hat nun eindeutige molekulare Signaturen ...

24.11.2025

DeutschesGesundheitsPortal

Braunschweig. Das Helmholtz-Zentrum für Infektionsforschung (HZI) bringt anlässlich seines 60. Jubiläums seine Forschung vom 3. ...

22.11.2025

Regional Heute

Universität Hannover (LUH), dem Helmholtz Zentrum für Infektionsforschung (HZI) in Braunschweig, der Technischen Universität Braunschweig ...

21.11.2025

Medizinische Hochschule Hannover

... 38100 Braunschweig Das Helmholtz-Zentrum für Infektionsforschung: Wissenschaftler:innen am Helmholtz-Zentrum für Infektionsforschung ( ...

20.11.2025

Bochumer-Zeitung

Dr. Dunja Bruder ist Forschungsgruppenleiterin am Helmholtz-Zentrum für Infektionsforschung in Braunschweig und zugleich Professorin für

20.11.2025

Bilanz

... Wissenschaftler und Wissenschaftlerinnen des Helmholtz-Zentrums für Infektionsforschung (HZI) und der Medizinischen Hochschule ...

19.11.2025

Rheinische Post

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