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Salmonella enterica, a foodborne pathogen, is one of four key global causes of diarrheal diseases, which affect over 550 million people each year. This rod-shaped, Gram-negative bacterium has tubular, whip-like appendages known as flagella that protrude from its surface. Researchers from the Centre for Structural Systems Biology (CSSB) in collaboration with researchers at Research Center Borstel FZB, as well as Max Plank Institute for Infection Biology, the University of Marburg and the Technische Universität Braunschweig studied biochemical and biophysical properties of these bacterial structures. Their study was recently published in PLoS Pathogens. The CSSB is a common initiative by ten northern German research institutions, including the Helmholtz Centre for Infection Research (HZI) in Braunschweig.

From July 2020 to August 2021, a research team from the HZI, with external support, studied the antibody status of more than 26,000 people in seven county districts and thus collected important data on the pandemic event.

Though the Corona pandemic is not over yet, we should already start preparing for future pandemics. A look at what infection research can contribute.

Hepatitis B is a viral infection of the liver that can lead to cancer and organ failure. Antiviral therapies can suppress the infection, but a functional cure is rare. Novel immunotherapies may lead to an actual cure more often. However, it is still unclear which patients benefit most from these new therapies. Researchers at the Centre for Individualised Infection Medicine (CiiM), a joint institution of the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School (MHH), as well as the MHH and the German Center for Infection Research (DZIF), have now identified a biomarker that intends to enable predictions about the success of the therapy. The results were published in the scientific journal Gut.

The Helmholtz Centre for Infection Research (HZI) in Braunschweig and the McGill Interdisciplinary Initiative in Infection and Immunity (MI4) at McGill University in Montréal, Canada, are organising a joint symposium on personalised infection medicine on 29 November. Three researchers from each of the two institutions will give lectures on various topics of personalised infection medicine. The keynote lecture will be given by Prof Ugur Sahin, co-founder and CEO of BioNTech SE. The symposium kicks off McGill University's “Infection and Immunity Week”, which celebrates its 200th anniversary this year. Interested scientists can register to follow the event online.