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Displaying results 671 to 680 of 686.
Universal Flu Vaccine Candidate Protects Against Infection in Animal Models
Researchers at Cleveland Clinic’s Lerner Research Institute and the HZI have reported that their universal flu vaccine candidate elicited a strong immune response and provided protection against severe infection and rapid clearance after viral exposure in ferrets. This…
Innate Immunity and Infection
The moment a pathogen, which has successfully entered the body, is recognized, the body quickly mobilizes its defenses. Interferons are molecules that are counted among the body’s first line of defense. They prevent proliferation and the spread of viruses in the body and serve to alert the immune system. Read here about the different ways we use to try and decode this system, all in an effort to find new approaches to infectious disease prevention and therapy.
Why the flu vaccine is less effective in older people
Every year at the beginning of October, the flu epidemic rolls around. “Because older people in particular have an increased risk of a severe course of the disease, effective vaccines are especially important for them,” says Prof. Yang Li, Scientific Director of the…
New drugs from toxic birds
The New Guinea-based regent whistler, or Pachycephala schlegelii in Latin, is a strange bird. It carries batrachotoxin in its black and yellow plumage: a potent neurotoxin, also used by poison dart frogs to effectively protect themselves from predators. This toxin is…
Enter the world of infection research - Open Day at the HZI
During guided tours, HZI researchers explain, for example, how new active substances against infections can be developed from natural products or how they use epidemiological studies to understand the spread of diseases and contribute to the health of the population. In…
Anti-infectives from Microbiota
The department of Prof Christine Beemelmanns focuses on the identification and functional analysis of novel anti-infective natural products from microbial communities. Co-cultivation studies as well as cell-based assays in combination with chemical-analytical and molecular-biological methods are used to evaluate and prioritize novel natural product producers. The department uses established and innovative metabolomic-, activity and genome-based methods to identify and determine the structure of the secreted natural products. Based on the isolated novel natural substances, the functional analysis and evaluation of their range of effects is carried out. This department is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) .
Sounds and Science - Music and Infections
Sounds and Science - Vienna meets Braunschweig The event is based on the successful “Sounds and Science” concert series, which was launched in 2014 with the participation of the Medical University of Vienna in Austria. “With the ‘Sounds and Science - Music and…
Microbiome research: Small RNA plays a crucial role in colonization
The intestinal microbiome is a highly complex ecosystem with thousands of different types of bacteria. Live and let live, that is the motto. Harmonious coexistence is based on the fact that intestinal bacteria occupy different niches and communicate with each other.…
Bacterial Infection Ecology
Microbial communities colonise many parts of our bodies, critically impacting our health such as by protecting against pathogens. But how the diverse microbes arrange and organise themselves to generate health effects is largely unknown. To tackle this challenge, we are developing methods to map the structure of the microbiome and resolve how this structure affects health benefits. In addition, we study how microbiota influence and manipulate us, aiming for real translational and clinical potential including the development of probiotic anti-infectives and microbiota-inspired immunotherapeutics.
