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Eliminating hepatitis C viruses effectively
Some 400,000 people around the world succumb to the consequences of a hepatitis C infection each year. The hepatitis C virus is usually transmitted by blood. An infection can remain undetected for long periods of time, because the disease initially progresses largely…
HZI coordinates the development of a nasal vaccination against Chagas disease
Chagas disease, also known as American Trypanosomiasis, is a chronic parasitic disease caused by the flagellated protozoan Trypanosoma cruzi. It is a vector-borne disease, but the parasite can also be transmitted by congenital route, blood transfusions and organ…
Natural antibiotics: Joining forces in the fight against resistant bacteria
The infectious agents Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa are Gram-negative bacteria and much-feared around hospitals. Due to their double cell wall, these germs are difficult to control and are among the most…
HZI Active substance researcher wins DECHEMA-Doktorandenpreis
Biofilms are surface-adherent aggregates of bacteria that are embedded in a slimy matrix, in which the bacteria protect themselves against the immune system or by antibiotics. Infections with these bacteria are therefore particularly difficult to treat. The microporenic…
New Clinical Director at the HZI
"Markus Cornberg being a DZIF professor and an active clinician will allow us to set up an important bridge to the clinical area in general and to the MHH in particular, strengthening the translational goals of the HZI. We are looking forward very much to our future…
The HZI mourns the death of Nobel Prize winner Manfred Eigen
Manfred Eigen received more honours than practically any other German scientist. Eigen was awarded the Nobel Prize in 1967 for his work on ultra-fast chemical reactions; he was the first scientist to measure the miniscule durations of such processes. In addition to the…
Biological diversity of habitats throughout the world is a treasure trove
For drug discovery to be successful, projects with an international scope play a particularly important role, since they make the large biological diversity of unusual habitats accessible. "We have recently obtained so many new and untapped microorganisms and fungi with…
Hunting pathogens at full force
Researchers of the Helmholtz Centre for Infection Research (HZI) and the Technische Universität Braunschweig have now elucidated the molecular mechanisms that allow cells to move forward effectively, using powerful cell edge protrusions. By applying the CRISPR/Cas…
Deciphering the motility apparatus of bacteria
Even for bacteria it is not satisfactory to just drift through life: Because every day is full of situations, in which a bacterium needs to move actively in its environment – for example when it searches for food or a suitable host. Under these circumstances, the…
Vaccination against liver infections
Similar to some other viruses, the hepatitis C virus specifically infects the liver and can cause a life-threatening chronic infection. Discovered in 1989, the virus thus far has managed to evade attempts at developing an effective vaccination. One of the underlying…
