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Displaying results 81 to 90 of 738.
HZI Molecule Transformed into a Cancer Medicine in the United States
The pharmaceutical company Bristol-Myers Squibb (BMS) recently obtained approval in the American market for IXEMPRA, a semi-synthetic analog of epothilone B, for the treatment of patients with metastatic breast cancer resistant or refractory to anthracyclines, taxanes,…
A new Knowledge Website for Infection Research
From antibiotic resistance to zoonotic diseases, from the developing to the developed world, infectious disease remains a profound health threat. Stay abreast of the latest research in infection at the new knowledge website „Infection Research-News and Perspectives“…
Dumping Useless Genes
Bacteria are genetically equipped with tremendous variability. As a result, these microorganisms are extremely flexible in their responses to the surrounding environment. From the standpoint of biotechnology, many bacterial genes are useful, while others are not.…
Why Mice Succumb to Human Diseases
The bacterium Listeria monocytogenes is able to infect humans causing diarrhea, meningitis, still birth or miscarriage. Mice, by contrast, are largely immune. This difference may be traced to the bacterial protein Internalin (or InlA), a molecular key that provides the…
Award for Indian HZI researcher
In Kochi, India, the HZI scientist Prof Gursharan Singh Chhatwal was honoured today with the Pravasi Bharatiya Samman Award 2013. With this award, the Indian government dignifies the merits of non-resident Indians that have helped to improve the international reputation…
Natural killer cells – the body’s own patrol against viruses and tumours
Scientists at the Helmholtz Centre for Infection Research (HZI) have analysed for the first time all the proteins inside natural killer (NK) cells of healthy individuals. The newly discovered “protein repertoire” shows that these immune cells cannot only defend us…
Serum Institute of India acquires rights to German Tb vaccine
Hopes are high for a new and improved tuberculosis vaccine: Serum Institute of India is planning on taking a promising vaccine - originally developed in Germany - and introducing it into the clinical setting. Studies have shown that the new vaccine is more effective and…
3D molecular syringes
Abdominal pain, fever, diarrhoea – these symptoms could point to an infection with the bacterium Yersinia. The bacterium’s pathogenic potential is based on a syringe-like injection apparatus called injectisome. For the first time, an international team of researchers…
A life-changing decision
A proper immune response relies largely on the right balance between effector and suppressor T cells. This balance is needed to fight off pathogens while at the same time avoiding tissue damage. Researchers at the Helmholtz Centre for Infection Research (HZI) in…
Researchers discover bacteria-killer from natural source
Pathogens of infectious diseases like Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumanii and Pseudomonas aeruginosa, share two major features: They are gram-negative bacteria and they are feared very much in hospital settings. Scientists from the Helmholtz…
