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Small molecule with high impact
The adjuvants present in vaccines have a bad reputation. For most people, they are only unnecessary compounds within a medicinal product. This is a misunderstanding since adjuvants have a critical impact on the success of a vaccination. In the best case scenario, one…
Rejuvenating the old immune system
Thanks to the progress in health care and improved living conditions, we live longer. The price we pay: Our immune system loses functionality with advance age and the susceptibility to infections increases. The members of the research group "Infection immunology" at the…
The Exhausted Immune Defence
After an initial acute infection, Staphylococci can persist in our body for a long period of time leading to chronic disease. Scientists from the Helmholtz Centre for Infection Research (Helmholtz-Zentrum für Infektionsforschung, HZI) in Braunschweig, Germany, have…
Intimate Binding to Intestinal Cells
Every year infections with "entero-hemorrhagic Escherichia coli " bacteria (EHEC) keep researchers in industrialised countries busy. During an infection the bacteria colonize the intestinal mucosa and produce a toxin that causes bloody diarrhoea, leading to severe…
Das HZI bekommt Nachwuchs
Marc Erhardt, Till Strowig und Alexander Titz haben sich in einem strengen Wettbewerbsverfahren durchgesetzt und werden nun mit jeweils 250.000 Euro über fünf Jahre gefördert. Sie werden am Helmholtz-Zentrum für Infektionsforschung (HZI) forschen und sich an der Lehre…
Working together against Alzheimer's, Parkinson's and dementia
Two institutions of the Helmholtz Association are joining forces for health research: How does the brain protect itself from pathogens? Can infections favour Alzheimer's disease? Scientists from the German Center for Neurodegenerative Diseases (DZNE) in Bonn and the…
The mystery of the third signal
At least three protective mechanisms defend the lungs against erroneous attacks by the body's own immune system. This was discovered by the Immuneregulation research group headed by Professor Dunja Bruder at the Helmholtz Centre for Infection Research (HZI) in…
Experts on infection meet in Braunschweig
Pathogens and their molecular “weapons“, mechanisms of immune defence, new therapies and agents against bacteria and viruses: this year’s program of the „North Regio Day on Infection“, in short “NoRDI”, offers a multitude of topics dealing with infection research. The…
The body's own recycling system
Times of distress literally eat away at the core of starving cells: They start to digest their own parts and recycle them for metabolic purposes. This process – called autophagy – also plays a role in immune defense. In that context, however, the digestive machinery is…
Salmonella as a tumour medication
Cancer diseases are some of the most common causes of death throughout the world, and they are still gaining in significance as the average general population gets older. However, we still do not have a satisfactory therapy for many types of tumours. One extremely…
