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Who benefits from immunotherapy against hepatitis B?
It is estimated that more than 250 million people worldwide are chronically infected with the hepatitis B virus. Cytotoxic T cells and T helper cells play an important role in fighting viral infections. The constant activation of these immune cells in chronically…
Joint symposium of HZI and McGill University on personalised infection medicine
Personalised infection medicine aims to take into account individual differences in the diagnosis and therapy of infectious diseases. The HZI and McGill University have been building a strategic cooperation on this topic for several years. Clinicians and scientists from…
20 research, medical and pharmaceutical organizations call on G7 to step up action against antibiotic resistance
They emphasise that it is important to ensure that more incentives are provided for research and development on new anti-bacterial drugs, that new antibiotics against problem germs reach patients quickly, that the potential of vaccines to reduce the risk of bacterial…
How molecular forces regulate cell migration
Twisted rods made of the protein actin are major constituents in our muscles. These rods, termed actin filaments, are not only crucial to muscle contraction, but also form networks and bundles that contribute to the skeleton of all our body cells. Such filaments…
Cease-fire for resistant germs
The hospital germ Pseudomonas aeruginosa causes a variety of infectious diseases: from pneumonia to wound, eye and urinary tract infections to sepsis. Pneumonia caused by P. aeruginosa poses a particular threat to cystic fibrosis and Covid-19 patients during artificial…
The HZI is on the leap to new antiviral agents
The Covid-19 pandemic, along with many previous epidemics, has clearly shown that viruses are a threat to human health worldwide. Despite the considerable success of vaccines, antiviral drugs are also needed to help those who are ill. For many viral diseases that have…
BMBF FUNDING "GO-BIO": HIRI RECEIVES UP TO 733,000 EUROS
It was a bit of a sensation earlier this year: The Helmholtz Institute for RNA-based Infection Research (HIRI) Würzburg in collaboration with the Julius Maximilian’s University (JMU) published new findings on CRISPR, the natural gene scissors that are part of bacterial…
A tiny molecule with a big impact
"Nitric oxide has two very different effects during an infection: On the one hand, it can directly destroy pathogens that have been taken up by phagocytes. On the other hand, above a certain concentration, it prevents the recruitment of further phagocytes to the site of…
Be Better Prepared for Pandemics
In the previous 15 years the World Health Organisation alone has had to proclaim six infection-caused global health emergencies. "The occurrence of further severe pandemics is but a matter of time," Prof Hans-Georg Kräusslich, chairman of the German Center for Infection…
Quest for bacterial cocktails to fight infections
The intestine of a healthy person contains hundreds of different bacteria that provide efficient protection against infections. However, if the equilibrium of this community, known as the microbiota, is disturbed – for example, due to antibiotic therapy – pathogens such…
