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"It's too early to ease restrictions"
At present, there are increasing demands to relax the restrictions on social life that have been imposed since mid-March. So far, it has remained relatively unclear how effective the restrictions are. Scientists led by the physicist Prof Michael Meyer-Hermann, head of…
Step-by-step Plan for after the Shutdown
The strategy envisions the gradual easing of current restrictions in a differentiated way and under continuous consideration of the risks. Priority will be given to restrictions that incur high economic costs or lead to severe social and health burdens. Regions with low…
SORMAS supports German health authorities in contact person management
The mobile eHealth system SORMAS (Surveillance, Outbreak Response Management and Analysis System) was developed at the Helmholtz Centre for Infection Research (HZI) together with national and international partners in response to the Ebola outbreak in West Africa in…
Bacteria alter their surface to infect host cells
The flagellums’ long, external filament is composed of several thousand copies of the same protein known as flagellin. The Gram-negative bacteria Salmonella Typhimurium express two distinct flagellins, FliC and FljB, which undergo the methylation of their lysine…
"We are not defenceless against the novel coronavirus"
Professor Heinz, a contact ban has been in effect in Germany since 23 March to slow down the spread of the novel coronavirus SARS-CoV-2. How sensible is this measure in your view? I currently regard the restriction of social contacts as a very important measure to give…
Population study investigates immunity to Covid-19
“Immune individuals could be issued with a kind of vaccination certificate, which would allow them to be exempted from restrictions on their activities, for example,” said Prof Gérard Krause, head of the HZI Department of Epidemiology, to the SPIEGEL. Project partners…
Attractive target for drug against coronavirus
The crystal structure of the enzyme Mpro was identified at a resolution of 1.75 Angstroms. An Angstrom is a unit of length equal to one ten-millionth of a millimetre. Mpro is a key enzyme in the coronavirus’ life cycle as it processes polyproteins that are translated…
Modified tuberculosis vaccine as a therapy for cancer of the bladder
Already at the end of the 19th century, doctors observed that the tumour in some cancer patients shrank if the patients suffered from a bacterial infection with a high fever. These findings sparked interest in immunotherapy for cancer. Immunomodulatory treatments can…
Hope for hepatitis B patients
Prof Carlos A. Guzmán, head of the HZI department “Vaccinology and Applied Microbiology”, together with his team developed the adjuvant c-di-AMP, which is incorporated in the TherVacB vaccine. “We will not only contribute c-di-AMP but also our expertise in order to…
New coronavirus module in SORMAS
Scientists of the Department "Epidemiology" at the HZI lead by Prof Gérard Krause together with German and international partners developed the mobile information system SORMAS. The system operates as an application on mobile phones and is particularly suitable for use…
