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Molecular Structural Biology
Combating infectious diseases depends critically on a deep understanding of the underlying molecular processes. Structural biology plays a crucial role in advancing biomedicine by providing valuable insights into the structure, function, and interactions of biological macromolecules at the atomic and molecular level. It combines state-of-the-art techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy and cryo-electron microscopy (cryo-EM) as well as advanced computer-based structure prediction methods to elucidate and analyze the three-dimensional structures of proteins, nucleic acids, and other biomolecules. Thus structural biology plays a critical role in infection research by providing a precise view on virulence factors, host-pathogen interactions, and the mechanisms of pathogenesis and host defense, paving the way towards the development of new anti-infectives and vaccines.
Molecular Bacteriology
Hospital-acquired infections are a major challenge and cause suffering, incapacity and death. In many cases the pathogens are resistant to antibiotics and, therefore, very difficult to combat. Read more about how bacteria join forces and what the researchers can do to avoid that. The group Molecular Bacteriology is based at the HZI and the TWINCORE in Hannover.
HZI spin-offs at a glance
HZI spin-offs at a glance Scientists at the HZI regularly and successfully transfer their results and technologies into start-ups and spin-offs. Here we present some of the companies. Leopard Biosciences GmbH SORMAS Foundation gGmbH InSCREENeX GmbH MyxoTech…
About HIRI
© Adobe Stock / Christoph Burgstedt Increasing antibiotic resistance, chronic infections and emerging pathogens pose major challenges for the public health system. While the central importance of RNA in regulatory and sensory cell processes has become…
