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When the hunters become the hunted
The immune system defends the body against pathogens. Macrophages are part of the first line of defence: they identify pathogens that have gained entry and destroy them. Bacteria that infiltrate the body are not powerless to resist the macrophages, however. Substances…
Casting show within the lymph nodes
Lymph nodes are the market place for the immune system; cells exchange information regarding invading pathogens here and prepare an appropriate immune response. What appears from the outside to be meaningless and chaotic teeming of millions of cells is actually a…
Mice with human body’s defences
Mice with human body’s defences 0B New method will simplify study and treatment of diseases Therapeutic antibodies can be an efficient alternative when common drugs do not work anymore. However, antibodies obtained from blood of animals such as mice could not be used:…
Helmholtz Centre for Infection Research mourns Scientific Director
Braunschweig, August 18, 2010 – The Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany is mourning the loss of its Scientific Director, Professor Jürgen Wehland, PhD. On August 16, 2010, Jürgen Wehland died unexpectedly during a vacation in Sweden.…
A new opportunity for hepatitis C research
The hepatitis C virus is highly specialised. We humans are its natural hosts. The only other living organisms that could be infected with the hepatitis C virus in the lab are chimpanzees. Nevertheless it is – from the viewpoint of the virus – highly successful: around…
The right response to every pathogen
In the event of an infection, the immune system releases messenger substances. These molecules can either activate immune cells to defeat invading pathogens, or inhibit them to prevent an excessive immune reaction. For this, the immune system has to decide very quickly…
New pathway to cheap Insulin
More than eight million diabetics live in Germany. Diabetes is not restricted to our prosperous society and the highest growth rates often occur in countries with aspiring economies such as in Asia. Worldwide, more than 285 million people suffer from this illness; with…
Helmholtz Centre for Infection Research receives project funding from the Bill und Melinda Gates Foundation
The Helmholtz Centre for Infection Research (HZI) has received a grant through the current round of the funding programme “Grand Challenges Explorations” of the Bill & Melinda Gates Foundation. The programme is supporting a global health project for development of…
Unexpected diversity of the nose
The human body is colonized by bacteria. They live on our skin, in our body’s orifices and throughout our gastrointestinal tract. There they can prevent dangerous germs (pathogens) from colonising and thus protect us against such infections, or they help in digestion.…
Small molecule with high impact
The adjuvants present in vaccines have a bad reputation. For most people, they are only unnecessary compounds within a medicinal product. This is a misunderstanding since adjuvants have a critical impact on the success of a vaccination. In the best case scenario, one…